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diltiazem and isoproterenol

diltiazem has been researched along with isoproterenol in 63 studies

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-199033 (52.38)18.7374
1990's15 (23.81)18.2507
2000's7 (11.11)29.6817
2010's8 (12.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ikegami, K; Sakanashi, M; Ueda, S; Yonemura, KI1
Takenaka, F; Takeo, S1
Drímal, J1
Awunor-Renner, C; Oliver, TB1
Ichikawa, H; Kawashima, Y; Koide, A; Komai, H; Nakashima, N; Ohashi, T; Shibata, T; Tanaka, K; Yamamoto, F; Yamamoto, H1
Mustafa, AA1
Nattel, S; Nayebpour, M1
Chiba, S; Matsuura, M; Zenda, H1
Auclair, MC; Lechat, P; Vernimmen, C1
Huff, JW; Reinach, PS1
Hattori, Y; Hazama, S; Kanno, M; Nakao, Y1
Mitra, R; Morad, M1
Akera, T; Ng, YC; Temma, K1
Hui, KK; Yu, JL1
Hunter, T; Proakis, A; Wu, KM1
Cohen, ML; Schoepp, DD; Secrest, RJ1
Henry, M; Kay, MM; Viccellio, P1
Carruthers, SG; Cordell, BA; McCall, B; Wu, R1
Clusin, W; Coetzee, WA; de Jong, JW; Dennis, SC; Opie, LH1
Brinkman, CJ; Huysmans, HA; Kappetein, AP; Los, GJ; van der Laarse, A; Weening, JJ1
Abdel-Rahman, AR; Ingenito, AJ1
Campbell, WB; Henrich, WL1
Campbell, WB; Henrich, WL; Needleman, P1
Kapur, PA; Sullivan, KB1
Kim, HD; Rah, BJ1
Dimich, I; Griffin, RM; Jurado, R; Kaplan, JA1
Bingham, WT; Duncan, WJ; Kasian, GF; Mersal, A; Ninan, A; Sankaran, K; Tyrrell, MJ1
Jolly, SR; Woltmann, R1
Hori, M; Inoue, M; Ito, H; Iwai, K; Kamada, T; Kitabatake, A; Kitakaze, M; Koretsune, Y; Tamai, J1
Lodge, NJ1
Arnold, TH; Tackett, RL1
Doane, JD; Matlib, MA; Riccippo-Neto, F; Sperelakis, N1
Jain, K; Kaur, AH; Singh, J; Singh, M1
Dobell, AR; Drinkwater, D; Hakim, TS; Hanson, RE; Keith, F; Michel, RP1
Briley, M; Cavero, I; Langer, SZ; Roach, AG1
Billette, J; Caillé, G; Cartier, R; Clozel, JP; Théroux, P1
Acconcia, MC; Gaspardone, A; Pannarale, G; Valente, A1
Kanda, M; Kitao, K; Osumi, S; Toda, N; Usui, H1
Ikezawa, K; Iwasawa, Y; Murata, S; Nagao, T; Sato, M1
Malik, KU; Schwartz, DD; Williams, JL1
Brezina, A; Kolin, A; Mamelak, M; Pandula, E1
Chiba, S; Kawai, K; Nakane, T1
Foot, EA; Leighton, B1
Horton, JW; White, DJ1
Kuettner, I; Ravingerova, T; Will-Shahab, L; Ziegelhoeffer, A1
Araki, H; Higuchi, S; Kishi-Tanikawa, S; Takahashi, K; Takahashi, T; Tsuchida, K1
Herrera, MD; Marhuenda, E; Perez-Guerrero, C1
Meera, P; Prakash, P; Tripathi, O1
Kiyota, T; Matsuda, F; Sadohara, T; Sugahara, K; Sugita, M; Terasaki, H1
Flameng, W; Macianskiene, R; Moccia, F; Mubagwa, K; Sipido, KR1
Carpenter, MK; Police, S; Rao, N; Xu, C1
Barclay, JK; Murrant, CL; Reading, SA1
Balasubramaniam, R; Chawla, S; Grace, AA; Huang, CL; Mackenzie, L; Schwiening, CJ1
Amtorp, O; Christensen, S; Jonassen, TE; Müllertz, KM; Pedersen, LR1
Inoue, T; Kaneko, N; Matsuda, R; Nishino, S; Oda, K; Otani, N1
Belardinelli, L; Machado, AD; Nearing, BD; Sobrado, LF; Varone, BB; Verrier, RL; Zeng, D1
Carrier, L; Eschenhagen, T; Flenner, F; Friedrich, FW; Geertz, B; Reischmann-Düsener, S; Weinberger, F1
Meng, T; Sun, C; Wei, Y1

Reviews

2 review(s) available for diltiazem and isoproterenol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Early pulmonary hypertension: current therapeutic prospectives].
    Cardiologia (Rome, Italy), 1982, Volume: 27, Issue:9

    Topics: Calcium Channel Blockers; Captopril; Diazoxide; Diltiazem; Humans; Hydralazine; Hypertension, Pulmonary; Isoproterenol; Nifedipine; Phentolamine; Time Factors

1982

Trials

2 trial(s) available for diltiazem and isoproterenol

ArticleYear
Relationships between heart rate and PR interval during physiological and pharmacological interventions.
    British journal of clinical pharmacology, 1987, Volume: 23, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Atrioventricular Node; Diltiazem; Electrocardiography; Female; Heart Rate; Humans; Isoproterenol; Male; Nifedipine; Physical Exertion; Receptors, Adrenergic, beta; Verapamil

1987
Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia.
    The Canadian journal of cardiology, 1988, Volume: 4, Issue:4

    Topics: Albuterol; Bronchopulmonary Dysplasia; Child, Preschool; Diltiazem; Humans; Hydralazine; Hypertension, Pulmonary; Infant, Newborn; Isoproterenol; Male; Nifedipine; Oxygen Inhalation Therapy; Pulmonary Heart Disease

1988

Other Studies

59 other study(ies) available for diltiazem and isoproterenol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Effects of prostaglandin E1 on isolated dog renal artery.
    Urology, 1979, Volume: 14, Issue:6

    Topics: Animals; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Papaverine; Phenoxybenzamine; Phentolamine; Potassium; Propranolol; Prostaglandin Antagonists; Prostaglandins E; Renal Artery; Theophylline

1979
Effects of diltiazem on high-energy phosphate contents reduced by isoproterenol in rat myocardium.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 228, Issue:2

    Topics: Adenosine Triphosphate; Animals; Benzazepines; Diltiazem; Hemodynamics; Isoproterenol; Lactates; Male; Myocardium; Phosphates; Phosphocreatine; Rats; Time Factors

1977
Modulation of high affinity phenylalkylamine binding sites on cultured human embryonal vascular smooth muscle cells.
    General physiology and biophysics, 1992, Volume: 11, Issue:6

    Topics: Binding Sites; Calcium Channels; Cells, Cultured; Diltiazem; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Kinetics; Magnesium; Muscle, Smooth, Vascular; Potassium; Verapamil

1992
Isoprenaline infusion and right ventricular pacing in severe diltiazem poisoning.
    The New Zealand medical journal, 1992, Nov-25, Volume: 105, Issue:946

    Topics: Adolescent; Cardiac Pacing, Artificial; Diltiazem; Female; Heart Ventricles; Humans; Infusions, Intravenous; Isoproterenol; Poisoning

1992
Harmful effects of inotropic agents on myocardial protection.
    The Annals of thoracic surgery, 1991, Volume: 52, Issue:4

    Topics: Animals; Body Temperature; Bucladesine; Calcium; Cardiotonic Agents; Creatine Kinase; Diltiazem; Hemodynamics; In Vitro Techniques; Isoproterenol; Male; Milrinone; Myocardial Reperfusion Injury; Pyridones; Rats; Rats, Inbred Strains; Ryanodine

1991
Rapid desensitization of central beta-adrenoceptors in rat after subacute treatment with imipramine and calcium entry blockers.
    Neuropharmacology, 1991, Volume: 30, Issue:8

    Topics: 1-Propanol; Animals; Calcium Channel Blockers; Clonidine; Diltiazem; DOM 2,5-Dimethoxy-4-Methylamphetamine; Drinking Behavior; Fenclonine; Imipramine; Isoproterenol; Ketanserin; Nicardipine; Nifedipine; Oxidopamine; Rats; Receptors, Adrenergic, beta; Verapamil

1991
Pharmacologic response of cesium-induced ventricular tachyarrhythmias in anesthetized dogs.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cesium; Chlorides; Chromatography, High Pressure Liquid; Diltiazem; Dogs; Electric Stimulation; Electrocardiography; Female; Heart Ventricles; Isoproterenol; Lidocaine; Magnesium Chloride; Male; Quinidine; Sodium Channels; Vagus Nerve

1990
Pharmacologic analysis of 7-O-ethyl-fangchinoline-induced vasodilation properties in isolated perfused common carotid arteries of Wistar Kyoto rats and spontaneously hypertensive rats.
    Chemical & pharmaceutical bulletin, 1991, Volume: 39, Issue:10

    Topics: Alkaloids; Animals; Atropine; Benzylisoquinolines; Carotid Arteries; Diltiazem; In Vitro Techniques; Isoproterenol; Male; Phenylephrine; Propranolol; Quinazolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction; Vasodilation; Vasodilator Agents

1991
[Effect of substances modifying calcium movement on the contractility of cultured cardiac cells].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1985, Volume: 179, Issue:1

    Topics: Animals; Caffeine; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Histamine; Imipramine; Ion Channels; Isoproterenol; Myocardial Contraction; Nifedipine; Phenylephrine; Rats; Verapamil

1985
Mechanism of inhibition of net ion transport across frog corneal epithelium by calcium channel antagonists.
    The Journal of membrane biology, 1985, Volume: 85, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bepridil; Calcimycin; Calcium Channel Blockers; Cornea; Cyclic AMP; Diltiazem; Electric Conductivity; Epithelium; In Vitro Techniques; Ion Channels; Isoproterenol; Kinetics; Pyrrolidines; Rana catesbeiana; Sodium-Potassium-Exchanging ATPase; Verapamil

1985
Inotropic effects of Ca2+ channel agonist and antagonists in neuraminidase-treated left atria of rats.
    British journal of pharmacology, 1986, Volume: 87, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Female; Heart Atria; In Vitro Techniques; Ion Channels; Isoproterenol; Male; Myocardial Contraction; N-Acetylneuraminic Acid; Neuraminidase; Nifedipine; Rats; Sialic Acids; Verapamil

1986
Two types of calcium channels in guinea pig ventricular myocytes.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:14

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Diltiazem; Gallopamil; Guinea Pigs; Heart Ventricles; Ion Channels; Isoproterenol; Kinetics; Metals; Myocardium; Nifedipine

1986
Effects of inotropic agents on isolated guinea pig heart under conditions that modify calcium pools involved in contractile activation.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:7

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cardiotonic Agents; Diltiazem; Diterpenes; Female; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Male; Monensin; Nifedipine; Ryanodine; Strophanthidin; Veratridine

1986
The effects of calcium channel blockers on isoproterenol induced cyclic adenosine 3',5'-monophosphate generation in intact human lymphocytes.
    Life sciences, 1988, Volume: 42, Issue:20

    Topics: 1-Methyl-3-isobutylxanthine; Calcium Channel Blockers; Cyclic AMP; Diltiazem; Drug Synergism; Humans; Isoproterenol; Kinetics; Lanthanum; Lymphocytes; Nifedipine; Phenothiazines; Verapamil

1988
Pharmacological characterisation of a re-entry model for atrial tachycardia in conscious dogs.
    Cardiovascular research, 1989, Volume: 23, Issue:5

    Topics: Acetylcholine; Action Potentials; Adrenergic Fibers; Animals; Anti-Arrhythmia Agents; Atropine; Cardiac Pacing, Artificial; Diltiazem; Dogs; Heart Atria; Heart Conduction System; Ion Channels; Isoproterenol; Neural Conduction; Ouabain; Propranolol; Tachycardia

1989
Comparison of contractions to serotonin, carbamylcholine and prostaglandin F2 alpha in rat stomach fundus.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:3

    Topics: Animals; Carbachol; Diltiazem; Dinoprost; Gastric Fundus; Guanidines; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Nitrendipine; Nitroglycerin; Phosphatidylinositols; Pinacidil; Rats; Rats, Inbred Strains; Serotonin

1989
Cardiogenic shock associated with calcium-channel and beta blockers: reversal with intravenous calcium chloride.
    The American journal of emergency medicine, 1985, Volume: 3, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Calcium Channel Blockers; Calcium Chloride; Digoxin; Diltiazem; Female; Humans; Isoproterenol; Male; Shock, Cardiogenic; Verapamil

1985
Effects of coronary flow, pacing rate, isoprenaline and diltiazem on ischemic ventricular arrhythmias in guinea pig hearts.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Calcium; Coronary Circulation; Coronary Disease; Diltiazem; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Potassium; Purines

1989
Assessment of hemodynamic function and tolerance to ischemia in the absence or presence of calcium antagonists in hearts of isoproterenol-treated, exercise-trained, and sedentary rats.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1988, Volume: 2, Issue:6

    Topics: Animals; Cardiomegaly; Cardioplegic Solutions; Creatine Kinase; Diltiazem; Fibrosis; Heart Arrest, Induced; Hemodynamics; Isoproterenol; Myocardium; Organ Size; Physical Education and Training; Rats; Verapamil

1988
Similarities and differences in the effects of verapamil, diltiazem and nifedipine on arterial baroreflexes of anesthetized cats.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 275, Issue:1

    Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Carotid Arteries; Cats; Diltiazem; Electric Stimulation; Female; Heart Rate; Isoproterenol; Male; Nifedipine; Pressoreceptors; Receptors, Adrenergic, beta; Receptors, Muscarinic; Reflex; Vagotomy; Vagus Nerve; Verapamil

1985
Importance of calcium in renal renin release.
    The American journal of physiology, 1986, Volume: 251, Issue:1 Pt 1

    Topics: Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; DDT; Diltiazem; Epoprostenol; Gallic Acid; Isoproterenol; Juxtaglomerular Apparatus; Kidney; Kidney Cortex; Male; Rats; Renin; Renin-Angiotensin System; Stimulation, Chemical

1986
Effect of atriopeptin III on renin release in vitro.
    Life sciences, 1986, Sep-15, Volume: 39, Issue:11

    Topics: Animals; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Diltiazem; Gallic Acid; In Vitro Techniques; Isoproterenol; Kidney Cortex; Rats; Renin; Secretory Rate

1986
The effect of beta-adrenergic blockade on the cardiovascular response to diltiazem or verapamil in dogs.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:11

    Topics: Animals; Catecholamines; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Isoproterenol; Male; Pentobarbital; Propranolol; Receptors, Adrenergic, beta; Verapamil

1986
Effects of diltiazem on isoproterenol- or Ca-induced ventricular myocardial cell injuries in isolated perfused rabbit heart: an electron microscopic study.
    The Anatomical record, 1988, Volume: 222, Issue:3

    Topics: Animals; Calcium; Diltiazem; Female; Heart; Heart Injuries; Heart Ventricles; Isoproterenol; Male; Microscopy, Electron; Myocardium; Perfusion; Rabbits

1988
Haemodynamic effects of diltiazem during fentanyl-nitrous oxide anaesthesia. An in vivo study in the dog.
    British journal of anaesthesia, 1988, Volume: 60, Issue:6

    Topics: Anesthesia, General; Animals; Calcium Chloride; Diltiazem; Dogs; Electrocardiography; Fentanyl; Hemodynamics; Isoproterenol; Nitrous Oxide; Time Factors

1988
Examination of diltiazem for preservation of myocardial function after brief regional ischemia.
    Pharmacology, 1987, Volume: 35, Issue:1

    Topics: Animals; Coronary Circulation; Coronary Disease; Diltiazem; Dogs; Heart; Hemodynamics; Isoproterenol; Male

1987
Cardiotonic activity of a new inotropic agent, 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), in the dog with and without beta-blocker and Ca++-antagonist pretreatment.
    Japanese circulation journal, 1986, Volume: 50, Issue:1

    Topics: Animals; Benzazepines; Blood Pressure; Cardiac Output; Cardiotonic Agents; Diltiazem; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Isoproterenol; Pharmaceutical Vehicles; Pyrazines; Quinolines; Thiophenes

1986
Ca2+ transport systems mediating the high K+/low Na+-induced uptake of Ca2+ into rat atrium.
    Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:11

    Topics: Animals; Biological Transport; Cadmium; Calcium; Choline; Diltiazem; In Vitro Techniques; Isoproterenol; Myocardium; Phosphates; Potassium; Rats; Sodium; Sodium Chloride

1986
Effects of magnesium on the action of vasodilatory agents.
    Pharmacology, 1985, Volume: 31, Issue:4

    Topics: Animals; Aorta, Thoracic; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Isoproterenol; Magnesium; Nitroglycerin; Rabbits; Vasodilation; Vasodilator Agents; Verapamil

1985
Clonazepam and diltiazem both inhibit sodium-calcium exchange of mitochondria, but only diltiazem inhibits the slow action potentials of cardiac muscles.
    Biochemical and biophysical research communications, 1985, Apr-16, Volume: 128, Issue:1

    Topics: Action Potentials; Animals; Benzazepines; Benzodiazepinones; Calcium; Clonazepam; Diltiazem; Guinea Pigs; Isoproterenol; Mitochondria, Heart; Myocardial Contraction; Sodium

1985
Effect of verapamil, nifedipine and diltiazem on experimental myocardial infarction in rats.
    Indian journal of experimental biology, 1985, Volume: 23, Issue:1

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Female; Isoproterenol; Male; Myocardial Infarction; Nifedipine; Rats; Verapamil

1985
Distribution of lung vascular resistance after chronic systemic-to-pulmonary shunts.
    The American journal of physiology, 1985, Volume: 249, Issue:6 Pt 2

    Topics: Animals; Blood Pressure; Diltiazem; Dogs; Histamine; Isoproterenol; Portasystemic Shunt, Surgical; Pulmonary Circulation; Serotonin; Vascular Resistance

1985
Evidence against beta-adrenoceptor blocking activity of diltiazem, a drug with calcium antagonist properties.
    British journal of pharmacology, 1980, Volume: 69, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Benzazepines; Calcium; Dihydroalprenolol; Diltiazem; Dose-Response Relationship, Drug; Heart Atria; Heart Rate; Isoproterenol; Male; Propranolol; Rats

1980
Effects of diltiazem on atrioventricular conduction and arterial blood pressure: correlation with plasma drug concentrations.
    Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:12

    Topics: Animals; Atrioventricular Node; Benzazepines; Blood Pressure; Diltiazem; Dogs; Heart Conduction System; Isoproterenol; Refractory Period, Electrophysiological; Verapamil

1984
Influence of trimetazidine, an antianginal drug, on isolated dog arteries and veins.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 260, Issue:2

    Topics: Animals; Diltiazem; Dinoprost; Dogs; Electric Stimulation; Female; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Nitroglycerin; Norepinephrine; Piperazines; Prostaglandins F; Trimetazidine

1982
[Bronchodilator actions of diltiazem in vitro and in vivo (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1981, Volume: 77, Issue:5

    Topics: Animals; Benzazepines; Bronchi; Bronchodilator Agents; Calcium; Cats; Diltiazem; Dogs; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth

1981
Contribution of calcium to isoproterenol-stimulated lipolysis in the isolated perfused rabbit heart.
    The American journal of physiology, 1993, Volume: 265, Issue:3 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium Channel Blockers; Cyclic AMP; Diltiazem; Gallic Acid; Glycerol; Heart; In Vitro Techniques; Isoproterenol; Lipolysis; Male; Myocardium; Quinolones; Rabbits

1993
Morphometry of reversible myocardial damage.
    Annals of the New York Academy of Sciences, 1994, Jun-17, Volume: 723

    Topics: Allopurinol; Animals; Cardiomyopathies; Cytoplasm; Diltiazem; Gerbillinae; Hydroxybutyrates; Isoproterenol; Lipid Metabolism; Male; Myocardium

1994
Mechanism of pindolol-induced vasoconstriction in isolated and perfused dog coronary arteries.
    Japanese journal of pharmacology, 1993, Volume: 62, Issue:1

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Coronary Vessels; Diltiazem; Dogs; Female; Femoral Artery; Histamine Antagonists; In Vitro Techniques; Isoproterenol; Male; Parasympatholytics; Perfusion; Pindolol; Potassium Chloride; Propranolol; Stereoisomerism; Vasoconstriction

1993
Effects of calcium antagonists on insulin-mediated glucose metabolism in skeletal muscle.
    Diabetes, 1994, Volume: 43, Issue:1

    Topics: Animals; Calcium Channel Blockers; Carbon Radioisotopes; Cyclic AMP; Diltiazem; Dose-Response Relationship, Drug; Glucose; Glycogen; Glycolysis; In Vitro Techniques; Insulin; Isoproterenol; Kinetics; Lactates; Male; Muscles; Nifedipine; Rats; Rats, Wistar; Verapamil

1994
Diminished cardiac contractile response to burn injury in aged guinea pigs.
    The Journal of trauma, 1993, Volume: 34, Issue:3

    Topics: Aging; Animals; Burns; Calcium Channels; Depression, Chemical; Diltiazem; Guinea Pigs; Isoproterenol; Male; Myocardial Contraction; Ventricular Function, Left

1993
Diltiazem prevents the depression of adenylyl cyclase activity induced by the calcium paradox in rat.
    Cardioscience, 1993, Volume: 4, Issue:3

    Topics: Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP; Diltiazem; Enzyme Activation; Isoproterenol; Male; Myocardium; Perfusion; Rats; Receptors, Adrenergic, beta; Sodium Fluoride

1993
Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; Dogs; Female; Heart Rate; Isoproterenol; Male; Myocardial Ischemia; Niacinamide; Nifedipine

1996
Smooth muscle relaxant effects of tetrazepam on isolated guinea-pig and rat trachealis.
    Journal of autonomic pharmacology, 1996, Volume: 16, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Calcium Channel Blockers; Carbachol; Diltiazem; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Isoquinolines; Male; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth; Potassium; Propranolol; Rats; Receptors, GABA-A; Trachea

1996
Effects of calcium channel blockers on spontaneous electrical activity of freshly isolated three-day-old embryonic chick ventricle.
    Reproduction, fertility, and development, 1996, Volume: 8, Issue:5

    Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Chick Embryo; Diltiazem; Dose-Response Relationship, Drug; Fendiline; Heart Ventricles; In Vitro Techniques; Isoproterenol; Nifedipine; Regression Analysis; Tetrodotoxin; Ventricular Function; Verapamil

1996
Comparative effect of amrinone, aminophylline and diltiazem on rat airway smooth muscle.
    Acta anaesthesiologica Scandinavica, 2000, Volume: 44, Issue:6

    Topics: Acetylcholine; Adrenergic beta-Agonists; Aminophylline; Amrinone; Animals; Bronchodilator Agents; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Isoproterenol; Milrinone; Muscle Relaxation; Muscle, Smooth; Rats; Rats, Wistar; Trachea

2000
Channels involved in transient currents unmasked by removal of extracellular calcium in cardiac cells.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cesium; Chelating Agents; Diltiazem; Drug Resistance; Egtazic Acid; Electric Conductivity; Heart Ventricles; Isoproterenol; Kinetics; Magnesium; Membrane Potentials; Myocardium; Nifedipine; Patch-Clamp Techniques; Potassium; Receptors, Adrenergic, beta; Swine; Verapamil

2002
Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells.
    Circulation research, 2002, Sep-20, Volume: 91, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Azacitidine; Cell Differentiation; Cell Size; Decitabine; Diltiazem; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Embryo, Mammalian; Gene Expression Regulation; Humans; Immunohistochemistry; Isoproterenol; Ki-67 Antigen; Myocardium; Myosin Heavy Chains; Phenylephrine; Stem Cells; Time Factors; Tretinoin; Troponin I

2002
Increased cAMP as a positive inotropic factor for mammalian skeletal muscle in vitro.
    Canadian journal of physiology and pharmacology, 2003, Volume: 81, Issue:10

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Bucladesine; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cyclic AMP; Dantrolene; Diltiazem; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Mice; Muscle Relaxants, Central; Muscle, Skeletal; Sarcolemma; Sarcoplasmic Reticulum; Time Factors

2003
Nifedipine and diltiazem suppress ventricular arrhythmogenesis and calcium release in mouse hearts.
    Pflugers Archiv : European journal of physiology, 2004, Volume: 449, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Calcium; Calcium Channel Blockers; Cytosol; Diltiazem; Electric Stimulation; Heart; In Vitro Techniques; Isoproterenol; Mice; Mice, Inbred Strains; Myocytes, Cardiac; Nifedipine; Tachycardia, Ventricular

2004
Enhanced alveolar fluid clearance following 72 h of continuous isoproterenol infusion in rats.
    Acta physiologica (Oxford, England), 2012, Volume: 206, Issue:2

    Topics: Adrenergic beta-Agonists; Albumins; Amiloride; Animals; Blotting, Western; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Dose-Response Relationship, Drug; Epithelial Sodium Channels; Infusion Pumps, Implantable; Infusions, Subcutaneous; Isoproterenol; Male; Permeability; Pulmonary Alveoli; Rats; Rats, Wistar; Respiration, Artificial; Sodium Channel Blockers; Time Factors

2012
Protective effect of K201 on isoproterenol-induced and ischemic-reperfusion-induced ventricular arrhythmias in the rat: comparison with diltiazem.
    Journal of cardiovascular pharmacology and therapeutics, 2013, Volume: 18, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Diltiazem; Isoproterenol; Male; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Thiazepines

2013
Dronedarone's inhibition of If current is the primary mechanism responsible for its bradycardic effect.
    Journal of cardiovascular electrophysiology, 2013, Volume: 24, Issue:8

    Topics: Amiodarone; Analysis of Variance; Animals; Arterial Pressure; Benzazepines; Blood Pressure; Bradycardia; Diltiazem; Dronedarone; Isoproterenol; Ivabradine; Myocardial Contraction; Swine

2013
Diltiazem prevents stress-induced contractile deficits in cardiomyocytes, but does not reverse the cardiomyopathy phenotype in Mybpc3-knock-in mice.
    The Journal of physiology, 2017, 06-15, Volume: 595, Issue:12

    Topics: Animals; Calcium; Cardiomyopathy, Hypertrophic; Carrier Proteins; Diastole; Diltiazem; Heart Ventricles; Isoproterenol; Mice; Mutation; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Phenotype; Sarcomeres

2017
Protective effect of diltiazem on myocardial ischemic rats induced by isoproterenol.
    Molecular medicine reports, 2018, Volume: 17, Issue:1

    Topics: Animals; Calcium; Cardiotonic Agents; Connexin 43; Diltiazem; Disease Models, Animal; Isoproterenol; Male; Myocardial Ischemia; Myocardium; Rats; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1

2018