Page last updated: 2024-08-23

diltiazem and hydralazine

diltiazem has been researched along with hydralazine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199012 (57.14)18.7374
1990's1 (4.76)18.2507
2000's4 (19.05)29.6817
2010's4 (19.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Nara, Y; Note, S; Sato, T; Yamori, Y1
Ogihara, M1
Bingham, WT; Duncan, WJ; Kasian, GF; Mersal, A; Ninan, A; Sankaran, K; Tyrrell, MJ1
Nagao, T; Nakajima, H; Narita, H; Yamaguchi, I1
Schroeder, JS1
Russell, IJ; Walsh, RA1
Nagao, T; Narita, H; Yabana, H; Yamaguchi, I1
Acconcia, MC; Gaspardone, A; Pannarale, G; Valente, A1
Achimastos, A; Levenson, J; Safar, M; Simon, A; Temmar, M1
Benetos, AM; Bouthier, JE; Levenson, JA; Safar, ME; Simon, AC1
Howes, LG; Hutchinson, JS; Takata, Y1
Zsotér, TT1
Kawashima, A; Koike, H; Nishio, S; Ueno, Y1
Agodoa, LY; Appel, LJ; Bakris, GL; Charleston, J; Contreras, G; Gabbai, F; Greene, T; Hiremath, L; Jamerson, K; Kendrick, C; Kusek, JW; Lash, JP; Lea, J; Miller, ER; Phillips, RA; Rahman, M; Rostand, S; Toto, R; Wang, X; Wright, JT1

Reviews

4 review(s) available for diltiazem and hydralazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Combination therapy with isosorbide dinitrate: current status and the future.
    American heart journal, 1985, Volume: 110, Issue:1 Pt 2

    Topics: Angina Pectoris; Coronary Vasospasm; Diltiazem; Drug Therapy, Combination; Esophageal Achalasia; Exercise Test; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Nifedipine; Nitroprusside; Propranolol; Verapamil

1985
[Early pulmonary hypertension: current therapeutic prospectives].
    Cardiologia (Rome, Italy), 1982, Volume: 27, Issue:9

    Topics: Calcium Channel Blockers; Captopril; Diazoxide; Diltiazem; Humans; Hydralazine; Hypertension, Pulmonary; Isoproterenol; Nifedipine; Phentolamine; Time Factors

1982
Calcium antagonists.
    American heart journal, 1980, Volume: 99, Issue:6

    Topics: Action Potentials; Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Bronchial Spasm; Calcium; Diazoxide; Diltiazem; Hemodynamics; Humans; Hydralazine; Lanthanum; Muscle, Smooth; Myocardial Contraction; Nifedipine; Nitrites; Nitroprusside; Papillary Muscles; Verapamil

1980

Trials

2 trial(s) available for diltiazem and hydralazine

ArticleYear
Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia.
    The Canadian journal of cardiology, 1988, Volume: 4, Issue:4

    Topics: Albuterol; Bronchopulmonary Dysplasia; Child, Preschool; Diltiazem; Humans; Hydralazine; Hypertension, Pulmonary; Infant, Newborn; Isoproterenol; Male; Nifedipine; Oxygen Inhalation Therapy; Pulmonary Heart Disease

1988
A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:1

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Black or African American; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Diltiazem; Drug Administration Schedule; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Heart Rate; Humans; Hydralazine; Hypertension; Male; Middle Aged; Ramipril; Renal Insufficiency, Chronic; Treatment Outcome

2013

Other Studies

15 other study(ies) available for diltiazem and hydralazine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Effect of calcium antagonists on hypertension and diabetes in new hypertensive diabetic models.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 10

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diltiazem; Disease Models, Animal; Female; Glucose Tolerance Test; Heart; Hydralazine; Hypertension; Kidney; Nifedipine; Organ Size; Rats; Rats, Inbred SHR

1987
Effects of calcium channel blockers and hydralazine on epinephrine-induced hyperglycemia in vivo.
    Japanese journal of pharmacology, 1989, Volume: 50, Issue:2

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Epinephrine; Food Deprivation; Glucose Tolerance Test; Hydralazine; Hyperglycemia; Male; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Verapamil

1989
Calcium entry blockers: antihypertensive and natriuretic effects in experimental animals.
    The American journal of cardiology, 1985, Dec-06, Volume: 56, Issue:16

    Topics: Angiotensin II; Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dogs; Glomerular Filtration Rate; Heart Rate; Hydralazine; Kidney; Natriuresis; Nifedipine; Rana catesbeiana; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Renin-Angiotensin System; Urinary Bladder

1985
Selection of vasodilator therapy for severe Raynaud's phenomenon by sequential arterial infusion.
    Annals of the rheumatic diseases, 1985, Volume: 44, Issue:3

    Topics: Adult; Diltiazem; Female; Humans; Hydralazine; Infusions, Intra-Arterial; Male; Phenoxybenzamine; Plethysmography; Raynaud Disease; Regional Blood Flow; Tolazoline; Vasodilator Agents

1985
Hypotensive and diuretic actions of diltiazem in spontaneously hypertensive and Wistar Kyoto rats.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2

    Topics: Animals; Benzazepines; Blood Pressure; Diltiazem; Diuresis; Heart Rate; Hydralazine; Hypertension; Male; Natriuresis; Rats; Rats, Inbred Strains; Water-Electrolyte Balance

1983
[Comparative hemodynamic effects of 2 vasodilators: dihydralazine and diltiazem in permanent essential arterial hypertension].
    Archives des maladies du coeur et des vaisseaux, 1982, Volume: 75 Spec No

    Topics: Adult; Arteries; Arterioles; Benzazepines; Blood Pressure; Dihydralazine; Diltiazem; Heart Rate; Hemodynamics; Humans; Hydralazine; Hypertension; Middle Aged; Vascular Resistance; Vasodilator Agents

1982
Baroreflex response and vasodilating drugs in essential hypertension.
    Chest, 1983, Volume: 83, Issue:2 Suppl

    Topics: Adult; Benzazepines; Blood Pressure; Brachial Artery; Dihydralazine; Diltiazem; Heart Rate; Humans; Hydralazine; Hypertension; Isosorbide Dinitrate; Male; Middle Aged; Pressoreceptors; Reflex; Vascular Resistance

1983
Antihypertensive effect of diltiazem in young or adult rats of genetically hypertensive strains.
    Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:3

    Topics: Age Factors; Animals; Benzazepines; Blood Pressure; Depression, Chemical; Diltiazem; Dose-Response Relationship, Drug; Female; Hydralazine; Hypertension; Male; Rats; Rats, Inbred Strains; Time Factors

1983
Effect of beraprost sodium, a stable prostacyclin analogue, on pulmonary thromboembolism in mice.
    Thrombosis research, 1995, Jan-15, Volume: 77, Issue:2

    Topics: Administration, Oral; Alprostadil; Animals; Aspirin; Bridged Bicyclo Compounds; Collagen; Diltiazem; Drug Evaluation, Preclinical; Epinephrine; Epoprostenol; Fatty Acids, Monounsaturated; Fibrinolytic Agents; Heparin; Hydralazine; Injections, Intravenous; Isosorbide Dinitrate; Male; Mice; Nifedipine; Nitroprusside; Platelet Aggregation Inhibitors; Pulmonary Embolism; Superoxide Dismutase; Vasodilator Agents

1995