Page last updated: 2024-08-23

diltiazem and hexobarbital

diltiazem has been researched along with hexobarbital in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's5 (62.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Caron, G; Ermondi, G1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Koleva, M; Stoytchev, T1
Kastelova, A; Koleva, M; Staneva-Stoytcheva, D; Stoytchev, T1
Kastelova, A; Koleva, M; Staneva-Stoytcheva, D1

Other Studies

8 other study(ies) available for diltiazem and hexobarbital

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Liver monooxygenase activity after multiple application of nifedipin, verapamil and diltiazem.
    Acta physiologica et pharmacologica Bulgarica, 1990, Volume: 16, Issue:4

    Topics: Androstenedione; Animals; Calcium Channel Blockers; Diltiazem; Hexobarbital; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Nifedipine; Rats; Rats, Inbred Strains; Sleep; Verapamil

1990
Combined effect of propranolol with nifedipine or with diltiazem on rat liver monooxygenase activities.
    Toxicology letters, 1999, Mar-29, Volume: 105, Issue:2

    Topics: Adrenergic beta-Antagonists; Aminopyrine N-Demethylase; Animals; Calcium Channel Blockers; Cytochrome P-450 Enzyme System; Cytochromes b5; Diltiazem; Ethylmorphine-N-Demethylase; Hexobarbital; Hypnotics and Sedatives; Liver; Male; NADPH-Ferrihemoprotein Reductase; Nifedipine; Propranolol; Rats; Rats, Wistar; Sleep

1999
Changes in rat liver monooxygenase activities after administration of atenolol, nifedipine and diltiazem alone and in combination.
    Methods and findings in experimental and clinical pharmacology, 2000, Volume: 22, Issue:8

    Topics: Adrenergic beta-Antagonists; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Atenolol; Calcium Channel Blockers; Cytochrome P-450 Enzyme System; Cytochromes b5; Diltiazem; Drug Therapy, Combination; Ethylmorphine-N-Demethylase; Hexobarbital; Hypnotics and Sedatives; Liver; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nifedipine; Oxidoreductases; Rats; Rats, Wistar

2000