Page last updated: 2024-08-23

diltiazem and felodipine

diltiazem has been researched along with felodipine in 61 studies

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-199010 (16.39)18.7374
1990's28 (45.90)18.2507
2000's16 (26.23)29.6817
2010's7 (11.48)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Coassolo, P; Lavé, T; Schneider, G1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Evans, CA; Jolivette, LJ; Nagilla, R; Ward, KW1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Guido, S; Joseph, T1
Cheng, TO1
Fazzini, P; Pollavini, G; Pucci, PD; Zerauscheck, M1
Kjellstedt, A; Ljung, B; Orebäck, B1
Marwood, JF2
Keene, F; Lechner, W; Marth, C; Zech, J1
O'Donnell, SR; Wanstall, JC1
Barbieri, L; Camerini, F; Mestroni, L1
Ceschia, G; Pandullo, C; Pivotti, F; Salvi, A; Scardi, S1
Bush, LR; D'Alonzo, AJ; Evans, RM; Gaul, SL1
Bailey, BL; Johnson, JD; Mills, JS1
Schwartz, A; Tsai, LI; Wang, T1
Garde, E; Jørgensen, HS; Lassen, NA; Olsen, TS1
Bülow, A; Johansson, B1
Almkvist, H; Berglund, L; Björnsson, T; Fagher, B; Henningsen, N; Honkavaara, M; Naukkarinen, V; Nordenström, P; Sillanpää, J; Thulin, T1
Belott, TP; Cook, AK; Inscho, EW; Navar, LG; Ohishi, K1
Boyd, IW1
Lund-Johansen, P; Omvik, P1
Agrotis, A; Bobik, A; Little, PJ; Saltis, J1
Casez, JP; Jaeger, P; Takkinen, R; Villiger, L1
Horwhat, JD; Landry, FJ; Pinski, L; Tomich, D1
Block, LH; Eickelberg, O; Erne, P; Kohler, E; Roth, M1
Afonso, LC; Bedford-Rice, K; Raman, BB; Sowers, JR; Standley, PR1
Lim, YT; Ng, WL; Sim, EK; Yeo, TC1
Kikuchi, K; Sugawara, H; Tobise, K1
Marwood, JF; Okoro, EO1
White, CM1
Bossi, M; Tiberti, G1
Bailey, CP; Little, HJ; Molleman, A1
Mészáros, LG; Minarovic, I1
Seibold, JR; Sturgill, MG1
Bakris, GL; Bidani, AK; Griffin, KA; Picken, MM1
Chen, H; Daloze, P; Dumont, L; Lapointe, N; Qi, S; Xu, D1
Chern, MS; Lin, FC; Wu, D1
Laufen, H; Riedel, KD; Scharpf, F; Schumacher, T; Yeates, R; Zimmermann, T1
Beckey, NP; Korman, L; Parra, D1
Aggeli, C; Economou, E; Pitsavos, C; Stefanadis, C; Toutouza, M; Toutouzas, P; Tsioufis, K; Vasiliadou, K; Zervoudaki, A1
Karotsis, AK; Mastorantonakis, SE; Stergiou, GS; Symeonidis, A1
Minarovic, I; Zahradník, I; Zahradníková, A1
Avery, BA; Boddu, SP; Kuma, SV; Potharaju, S; Rajak, S; Repka, MA; Varanasi, VS; Veeraraghavan, S; Yamsani, MR1

Reviews

3 review(s) available for diltiazem and felodipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Calcium antagonists in congestive heart failure].
    Giornale italiano di cardiologia, 1988, Volume: 18, Issue:11

    Topics: Calcium Channel Blockers; Cardiomyopathy, Dilated; Diltiazem; Felodipine; Heart Failure; Hemodynamics; Humans; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Verapamil

1988
Calcium channel blockers in left ventricular dysfunction or congestive heart failure.
    Connecticut medicine, 1997, Volume: 61, Issue:10

    Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Felodipine; Heart Failure; Humans; Nicardipine; Nifedipine; Ventricular Dysfunction, Left; Verapamil

1997

Trials

7 trial(s) available for diltiazem and felodipine

ArticleYear
Acute effects on exercise tolerance of felodipine and diltiazem, alone and in combination, in stable effort angina.
    European heart journal, 1991, Volume: 12, Issue:1

    Topics: Angina Pectoris; Blood Pressure; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Felodipine; Heart Rate; Humans; Physical Exertion; Posture

1991
Efficacy and tolerability of felodipine ER and diltiazem SR as monotherapy in primary hypertension: a double-blind randomized study.
    Cardiovascular drugs and therapy, 1994, Volume: 8, Issue:6

    Topics: Blood Pressure; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged

1994
Felodipine as an alternative to more expensive calcium antagonists in mild to moderate hypertension.
    Southern medical journal, 1996, Volume: 89, Issue:6

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Drug Costs; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies; Treatment Outcome

1996
Comparison of clinical efficacy and adverse effects between extended-release felodipine and slow-release diltiazem in patients with isolated systolic hypertension.
    Changgeng yi xue za zhi, 1999, Volume: 22, Issue:1

    Topics: Adult; Aged; Calcium Channel Blockers; Diltiazem; Felodipine; Female; Humans; Hypertension; Male; Middle Aged

1999
The pharmacokinetics of extended-release formulations of calcium antagonists and of amlodipine in subjects with different gastrointestinal transit times.
    Journal of clinical pharmacology, 1999, Volume: 39, Issue:10

    Topics: Adult; Amlodipine; Area Under Curve; Biological Availability; Calcium Channel Blockers; Cross-Over Studies; Delayed-Action Preparations; Diltiazem; Felodipine; Female; Gastrointestinal Diseases; Gastrointestinal Transit; Headache; Humans; Male; Middle Aged; Time Factors

1999
The effect of Ca2+ channel antagonists on plasma concentrations of matrix metalloproteinase-2 and -9 in essential hypertension.
    American journal of hypertension, 2004, Volume: 17, Issue:3

    Topics: Adult; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Diastole; Diltiazem; Felodipine; Female; Heart Ventricles; Humans; Hypertension; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Systole; Treatment Outcome; Vascular Resistance

2004
Additional antihypertensive effect of drugs in hypertensive subjects uncontrolled on diltiazem monotherapy: a randomized controlled trial using office and home blood pressure monitoring.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2006, Volume: 28, Issue:7

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chlorthalidone; Diltiazem; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Office Visits; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome; Valine; Valsartan

2006

Other Studies

51 other study(ies) available for diltiazem and felodipine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
    Journal of medicinal chemistry, 1999, Dec-16, Volume: 42, Issue:25

    Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats

1999
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
    Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18

    Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Extrapolation of preclinical pharmacokinetics and molecular feature analysis of "discovery-like" molecules to predict human pharmacokinetics.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7

    Topics: Animals; Biometry; Dogs; Drug Evaluation, Preclinical; Haloperidol; Haplorhini; Humans; Injections, Intravenous; Liver; Liver Circulation; Metabolic Clearance Rate; Mifepristone; Molecular Structure; Molecular Weight; Rats; Reproducibility of Results

2006
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effect of chemically different calcium antagonists on lipid profile in rats fed on a high fat diet.
    Indian journal of experimental biology, 1992, Volume: 30, Issue:4

    Topics: Animals; Blood; Calcium; Clofibrate; Dietary Fats; Diltiazem; Felodipine; Lipids; Male; Nifedipine; Nimodipine; Rats; Rats, Inbred Strains; Verapamil

1992
All calcium channel blockers are not alike.
    International journal of cardiology, 1991, Volume: 32, Issue:2

    Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Felodipine; Heart Failure; Humans; Nifedipine

1991
Vascular versus myocardial selectivity of calcium antagonists studied by concentration-time-effect relations.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 1

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Felodipine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nitrendipine; Papillary Muscles; Rats; Rats, Inbred Strains; Time Factors; Verapamil

1987
Studies on the site of the interaction between alpha 1-adrenoceptors and 5-HT2 receptors in rat tail arteries.
    Journal of cardiovascular pharmacology, 1988, Volume: 11 Suppl 1

    Topics: Animals; Arteries; Binding Sites; Diltiazem; Felodipine; In Vitro Techniques; Male; Manganese; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Tail; Verapamil

1988
Calcium and calmodulin antagonism for inhibition of uterine contractions.
    Archives of gynecology and obstetrics, 1989, Volume: 244, Issue:3

    Topics: Calcium; Calmodulin; Culture Techniques; Diltiazem; Felodipine; Female; Humans; Nitrendipine; Pregnancy; Uterine Contraction

1989
Influence of age on calcium entry blocking drugs in rat aorta is spasmogen-dependent.
    European journal of pharmacology, 1989, Jan-17, Volume: 159, Issue:3

    Topics: Aging; Animals; Aorta; Calcium; Calcium Channel Blockers; Diltiazem; Drug Interactions; Felodipine; Male; Nitrendipine; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Serotonin

1989
Exercise-induced intermittent angina and ST-segment elevation in Prinzmetal's angina.
    European heart journal, 1988, Volume: 9, Issue:1

    Topics: Angina Pectoris, Variant; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Diltiazem; Electrocardiography; Exercise Test; Felodipine; Heart Conduction System; Humans; Male; Middle Aged; Nitrendipine

1988
Comparative effects of verapamil, diltiazem and felodipine during experimental digitalis-induced arrhythmias.
    Pharmacology, 1987, Volume: 34, Issue:2-3

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem; Dogs; Felodipine; Female; Male; Nitrendipine; Ouabain; Verapamil

1987
Cooperativity among calmodulin's drug binding sites.
    Biochemistry, 1985, Aug-27, Volume: 24, Issue:18

    Topics: Antihypertensive Agents; Benzazepines; Binding Sites; Calcium; Calmodulin; Diltiazem; Felodipine; Kinetics; Nifedipine; Prenylamine; Protein Binding; Spectrometry, Fluorescence

1985
Effects of verapamil, diltiazem, nisoldipine and felodipine on sarcoplasmic reticulum.
    European journal of pharmacology, 1984, May-04, Volume: 100, Issue:3-4

    Topics: Animals; Calcium Channel Blockers; Calcium-Transporting ATPases; Centrifugation, Density Gradient; Diltiazem; Dogs; Felodipine; In Vitro Techniques; Microsomes; Muscles; Myocardium; Nifedipine; Nisoldipine; Potassium Chloride; Rabbits; Sarcoplasmic Reticulum; Species Specificity; Verapamil

1984
[Reducing hypertension may worsen symptoms of acute apoplexy].
    Ugeskrift for laeger, 1995, Jun-19, Volume: 157, Issue:25

    Topics: Acute Disease; Aged; Cerebrovascular Disorders; Diltiazem; Felodipine; Humans; Hypertension; Male; Radionuclide Imaging; Risk Factors

1995
Membrane stretch evoked by cell swelling increases contractile activity in vascular smooth muscle through dihydropyridine-sensitive pathways.
    Acta physiologica Scandinavica, 1994, Volume: 152, Issue:4

    Topics: Animals; Calcium; Calcium Channel Blockers; Cell Membrane; Cell Size; Dihydropyridines; Diltiazem; Felodipine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Osmosis; Portal Vein; Rats; Rats, Sprague-Dawley; Stress, Mechanical; Verapamil

1994
Calcium activation mechanisms in the renal microvascular response to extracellular ATP.
    The American journal of physiology, 1995, Volume: 268, Issue:5 Pt 2

    Topics: Adenosine Triphosphate; Animals; Calcium; Diltiazem; Extracellular Space; Felodipine; Intracellular Membranes; Male; Microcirculation; Norepinephrine; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasoconstriction

1995
Adverse Drug Reactions Advisory Committee. Gynaecomastia in association with calcium antagonists.
    The Medical journal of Australia, 1994, Sep-05, Volume: 161, Issue:5

    Topics: Adult; Aged; Calcium Channel Blockers; Diltiazem; Felodipine; Gynecomastia; Humans; Male; Middle Aged; Nifedipine; Verapamil

1994
Long-term hemodynamic effects at rest and during exercise of newer antihypertensive agents and salt restriction in essential hypertension: review of epanolol, doxazosin, amlodipine, felodipine, diltiazem, lisinopril, dilevalol, carvedilol, and ketanserin.
    Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:2

    Topics: Adult; Amlodipine; Antihypertensive Agents; Benzeneacetamides; Carbazoles; Carvedilol; Diet, Sodium-Restricted; Diltiazem; Dipeptides; Doxazosin; Exercise; Felodipine; Female; Hemodynamics; Humans; Hypertension; Ketanserin; Labetalol; Lisinopril; Longitudinal Studies; Male; Middle Aged; Propanolamines

1993
Dihydropyridine Ca2+ channel antagonists inhibit the salvage pathway for DNA synthesis in human vascular smooth muscle cells.
    European journal of pharmacology, 1993, Feb-15, Volume: 244, Issue:3

    Topics: Calcium Channel Blockers; Cell Division; Cells, Cultured; Dihydropyridines; Diltiazem; DNA; Epidermal Growth Factor; Felodipine; Gene Expression Regulation; Genes, fos; Humans; Immunoblotting; Mammary Arteries; Muscle, Smooth, Vascular; Nisoldipine; Thymidine; Verapamil

1993
Diltiazem stimulates parathyroid hormone secretion in vivo whereas felodipine does not.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:4

    Topics: Adult; Analysis of Variance; Calcium; Diltiazem; Edetic Acid; Felodipine; Humans; Male; Parathyroid Hormone

1993
Ca2+ channel blockers modulate metabolism of collagens within the extracellular matrix.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11

    Topics: Amlodipine; Becaplermin; Calcium Channel Blockers; Cells, Cultured; Collagen; Collagenases; Dihydropyridines; Diltiazem; Enzyme Activation; Extracellular Matrix; Felodipine; Fibroblasts; Humans; Kinetics; Lung; Metalloendopeptidases; Muscle, Smooth, Vascular; Nitrobenzenes; Piperazines; Platelet-Derived Growth Factor; Procollagen; Proline; Proto-Oncogene Proteins c-sis; Transcription, Genetic; Verapamil

1996
Effects of antihypertensive therapy on platelet cytosolic calcium responses to low density lipoprotein cholesterol.
    Journal of human hypertension, 1996, Volume: 10, Issue:3

    Topics: Aged; Aged, 80 and over; Blood Platelets; Calcium; Cholesterol, LDL; Cytosol; Diltiazem; Drug Therapy, Combination; Enalapril; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Prospective Studies

1996
Surgery for left main spasm. Is it indicated?
    International journal of cardiology, 1996, Volume: 54, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiac Surgical Procedures; Chest Pain; Coronary Angiography; Coronary Vasospasm; Diltiazem; Drug Therapy, Combination; Felodipine; Humans; Isosorbide Dinitrate; Male; Nitroglycerin; Vasodilator Agents

1996
Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1996, Volume: 19, Issue:4

    Topics: Adenosine Diphosphate; Animals; Antioxidants; Calcium Channel Blockers; Cell Membrane; Dihydropyridines; Diltiazem; Felodipine; Fumarates; Heart; Iron; Lipid Peroxidation; Male; Myocardium; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Verapamil

1996
Effects of 5HT2 receptor antagonists on responses to potassium depolarization in rat isolated aorta.
    Clinical and experimental pharmacology & physiology, 1997, Volume: 24, Issue:1

    Topics: Animals; Aorta, Thoracic; Cinnarizine; Cyproheptadine; Diltiazem; Drug Synergism; Felodipine; Female; In Vitro Techniques; Ketanserin; Male; Mianserin; Muscle Contraction; Nifedipine; Potassium; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reproducibility of Results; Ritanserin; Serotonin Antagonists; Verapamil

1997
[Stable angina pectoris: what is the role of calcium antagonists?].
    Giornale italiano di cardiologia, 1997, Volume: 27, Issue:10

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Calcium Channel Blockers; Clinical Trials as Topic; Dihydropyridines; Diltiazem; Drug Therapy, Combination; Felodipine; Humans; Metoprolol; Multicenter Studies as Topic; Nifedipine; Randomized Controlled Trials as Topic; Verapamil

1997
Comparison of the effects of drugs on hyperexcitability induced in hippocampal slices by withdrawal from chronic ethanol consumption.
    British journal of pharmacology, 1998, Volume: 123, Issue:2

    Topics: Acetates; Alcoholism; Amines; Animals; Behavior, Animal; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Diltiazem; Ethanol; Felodipine; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Isradipine; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Substance Withdrawal Syndrome

1998
Fluorescent probing with felodipine of the dihydropyridine receptor and its interaction with the ryanodine receptor calcium release channel.
    Biochemical and biophysical research communications, 1998, Mar-17, Volume: 244, Issue:2

    Topics: Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Diltiazem; Dogs; Felodipine; Fluorescent Dyes; In Vitro Techniques; Isradipine; Kinetics; Muscle, Skeletal; Myocardium; Protein Conformation; Rabbits; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcolemma; Sarcoplasmic Reticulum; Spectrometry, Fluorescence

1998
Rational use of calcium-channel antagonists in Raynaud's phenomenon.
    Current opinion in rheumatology, 1998, Volume: 10, Issue:6

    Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Felodipine; Humans; Isradipine; Nicardipine; Nifedipine; Raynaud Disease

1998
Class differences in the effects of calcium channel blockers in the rat remnant kidney model.
    Kidney international, 1999, Volume: 55, Issue:5

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Disease Models, Animal; Drinking; Felodipine; Glomerulosclerosis, Focal Segmental; Homeostasis; Hypertension, Renal; Hypertrophy; Kidney Glomerulus; Male; Nephrectomy; Proteinuria; Radio Waves; Rats; Rats, Sprague-Dawley; Telemetry; Verapamil

1999
Immunomodulating effects of second-generation calcium channel blockers on experimental heart transplantation.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1999, Volume: 31, Issue:3

    Topics: Adjuvants, Immunologic; Amlodipine; Animals; Benzimidazoles; Calcium Channel Blockers; Cyclosporine; Diltiazem; Drug Therapy, Combination; Felodipine; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Male; Mibefradil; Rats; Rats, Inbred Lew; Tetrahydronaphthalenes; Time Factors

1999
Retrospective evaluation of the conversion of amlodipine to alternative calcium channel blockers.
    Pharmacotherapy, 2000, Volume: 20, Issue:9

    Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Diltiazem; Felodipine; Female; Humans; Hypertension; Male; Nifedipine; Retrospective Studies

2000
Studies on the interactions between the angiotensin converting enzyme inhibitor enalaprilat and calcium antagonists in rats.
    Journal of hypertension, 1996, Volume: 14, Issue:1

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; Cinnarizine; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Enalaprilat; Felodipine; Female; Male; Models, Animal; Models, Cardiovascular; Rats; Rats, Sprague-Dawley; Verapamil

1996
Competitive and cooperative effects of Bay K8644 on the L-type calcium channel current inhibition by calcium channel antagonists.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Algorithms; Allosteric Regulation; Animals; Binding Sites; Binding, Competitive; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Felodipine; Ion Channel Gating; Male; Membrane Potentials; Models, Biological; Myocytes, Cardiac; Patch-Clamp Techniques; Protein Binding; Rats; Rats, Wistar; Verapamil

2007
Influence of grapefruit juice on the pharmacokinetics of diltiazem in Wistar rats upon single and multiple dosage regimens.
    Die Pharmazie, 2009, Volume: 64, Issue:8

    Topics: Animals; Beverages; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Citrus paradisi; Cytochrome P-450 CYP3A; Diltiazem; Drug Interactions; Duodenum; Felodipine; In Vitro Techniques; Intestinal Absorption; Liver; Male; Pharmaceutical Preparations; Rats; Rats, Wistar; Subcellular Fractions

2009