diltiazem has been researched along with endothelin-1 in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (45.83) | 18.2507 |
| 2000's | 8 (33.33) | 29.6817 |
| 2010's | 5 (20.83) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aotsuka, T; Asakura, R; Ashizawa, N; Kobayashi, F; Matsuura, A; Okumura, H | 1 |
| Fujita, M; Kageyama, M; Shirasawa, E | 1 |
| Edenbaum, LR; Gurbel, PA; Herzog, WR; Schlossberg, ML; Serebruany, VL | 3 |
| Keiser, HR; Oriji, GK | 1 |
| Briggs, PJ; Moran, CG; Wood, MB | 1 |
| Asberg, A; Berg, KJ; Christensen, H; Hartmann, A | 1 |
| Fujishima, M; Hirano, K; Hirano, M; Kanaide, H; Kawasaki, J; Nishimura, J | 1 |
| Cao, W; Guo, Z; Luo, W; Zeng, Z; Zhu, Y | 1 |
| Oriji, GK | 1 |
| Ikegaki, I; Sasaki, Y; Uchida, T; Yamamoto, Y | 1 |
| Fleming, JB; Khalil, RA; Sirous, ZN | 1 |
| Chester, MR; Conant, AR; Dihmis, WC; Oo, AY; Shackcloth, MJ; Simpson, AW | 1 |
| Khalil, RA; McNair, LL; Salamanca, DA | 1 |
| Jernigan, NL; Resta, TC; Walker, BR | 1 |
| Lewis, SJ; Lewis, TH; Moore, JN; Noschka, E; Peroni, JF; Robertson, TP | 1 |
| He, H; Li, L; Shi, M; Wu, L; Yang, J; Yang, X; Zeng, X | 1 |
| El-Awady, MS; Smirnov, SV; Watson, ML | 1 |
| Almasri, M; Burger, D; Callera, GE; Chignalia, AZ; He, G; He, Y; Krause, KH; Lambeth, D; Montezano, AC; Paravicini, TM; Quinn, MT; Touyz, RM; Yusuf, H | 1 |
| Li, Q; Li, X; Sun, X; Wu, Z; Yang, H; Yang, J; Zhang, X; Zhao, J | 1 |
| Kathol, I; Loutzenhiser, K; Loutzenhiser, R; Takeya, K; Walsh, MP; Wang, X | 1 |
| Li, J; Li, M; Liu, X; Meng, G | 1 |
| Chen, C; Chen, W; Ma, Y; Nong, Z; Qiu, S; Wu, G | 1 |
1 trial(s) available for diltiazem and endothelin-1
| Article | Year |
|---|---|
Effects of combination of statin and calcium channel blocker in patients with cardiac syndrome X.
Topics: Calcium Channel Blockers; China; Coronary Circulation; Coronary Vessels; Diltiazem; Drug Therapy, Combination; Endothelin-1; Exercise Tolerance; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Microvascular Angina; Middle Aged; Nitric Oxide; Prospective Studies; Time Factors; Treatment Outcome | 2014 |
23 other study(ies) available for diltiazem and endothelin-1
| Article | Year |
|---|---|
Possible involvement of different mechanisms in sudden death induced by endothelin-1 and big endothelin-1.
Topics: Anesthesia; Animals; Death, Sudden, Cardiac; Diltiazem; Electrocardiography; Endothelin-1; Endothelins; Glycopeptides; Kidney; Lung; Male; Mice; Mice, Inbred ICR; Myocardial Ischemia; Myocardium; Potassium; Protease Inhibitors; Protein Precursors | 1995 |
Endothelin-1 mediated Ca2+ influx does not occur through L-type voltage-dependent Ca2+ channels in cultured bovine trabecular meshwork cells.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Carbachol; Cattle; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Endothelin-1; Fluorescent Dyes; Fura-2; Muscarinic Agonists; Norepinephrine; Receptors, Endothelin; Signal Transduction; Trabecular Meshwork | 1996 |
Intracoronary magnesium and diltiazem affect to a similar extent certain hemostatic factors during acute myocardial infarction in swine.
Topics: Animals; Antithrombin III; Blood Coagulation Factors; Calcium Channel Blockers; Diltiazem; Eicosanoids; Endothelin-1; Female; Fibronectins; Hemodynamics; Magnesium; Myocardial Infarction; Myocardial Reperfusion Injury; Protein C; Protein S; Swine | 1996 |
Role of calcium in endothelin-induced contractions and prostacyclin release.
Topics: Animals; Aorta; Calcium; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Endothelin-1; Epoprostenol; Male; Muscle Contraction; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Thapsigargin | 1996 |
Effects of intracoronary diltiazem on certain hemostatic parameters during acute myocardial infarction in swine.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Disease Models, Animal; Eicosanoids; Endothelin-1; Female; Fibronectins; Hemostasis; Infusions, Intra-Arterial; Myocardial Infarction; Swine | 1997 |
Actions of endothelin-1, 2, and 3 in the microvasculature of bone.
Topics: Animals; Bone and Bones; Diltiazem; Dogs; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-2; Endothelin-3; Microcirculation; Norepinephrine | 1998 |
Serial changes of soluble endothelin-1 levels during myocardial ischaemia-reperfusion. Effects of magnesium, diltiazem and a novel MAC-1 inhibitor.
Topics: Animals; Diltiazem; Endothelin-1; Female; Leucine; Macrophage-1 Antigen; Magnesium; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Swine | 1998 |
Diltiazem modulates cyclosporin A induced renal hemodynamic effects but not its effect on plasma endothelin-1.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cyclosporine; Diltiazem; Endothelin-1; Female; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Renal Circulation; Vasoconstriction | 1998 |
Troglitazone inhibits the capacitative Ca2+ entry in endothelial cells.
Topics: Adenosine Triphosphate; Animals; Aorta; Bradykinin; Calcium; Calcium Channel Blockers; Cells, Cultured; Chromans; Diltiazem; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; Swine; Thapsigargin; Thiazoles; Thiazolidinediones; Time Factors; Troglitazone; Vasodilator Agents | 1999 |
[Effects of calcium channel blockers and calmodulin inhibitors on the secretion of endothelin-1 in cultured endothelial cells].
Topics: Alkaloids; Benzylisoquinolines; Calcium Channel Blockers; Calmodulin; Cells, Cultured; Chlorpromazine; Diltiazem; Endothelin-1; Endothelium, Vascular; Humans; Nitroglycerin; Umbilical Veins; Verapamil | 1997 |
Endothelin-induced prostacyclin production in rat aortic endothelial cells: role of calcium.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Diltiazem; Endothelin-1; Endothelium, Vascular; Epoprostenol; Male; Phorbol 12,13-Dibutyrate; Rats; Thapsigargin | 1999 |
The protein kinase inhibitor fasudil protects against ischemic myocardial injury induced by endothelin-1 in the rabbit.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Movement; Diltiazem; Electrocardiography; Endothelin-1; Enzyme Inhibitors; Heart Ventricles; Macrophages; Male; Microscopy; Myocardial Ischemia; Necrosis; Neutrophils; Nicorandil; Nifedipine; Papillary Muscles; Rabbits; Random Allocation; Vasodilator Agents | 2000 |
Endothelin-1 enhances eicosanoids-induced coronary smooth muscle contraction by activating specific protein kinase C isoforms.
Topics: Animals; Blotting, Western; Calcium; Calcium Channel Blockers; Cell Separation; Coronary Vasospasm; Coronary Vessels; Diltiazem; Dinoprost; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Activation; Fura-2; In Vitro Techniques; Isoenzymes; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phorbol Esters; Protein Kinase C; Subcellular Fractions; Swine | 2001 |
Phenoxybenzamine treatment is insufficient to prevent spasm in the radial artery: the effect of other vasodilators.
Topics: Adrenergic alpha-Agonists; Aged; Angiotensin II; Coronary Artery Bypass; Diltiazem; Dose-Response Relationship, Drug; Endothelin-1; Humans; Middle Aged; Nitroglycerin; Norepinephrine; Papaverine; Peripheral Vascular Diseases; Phenoxybenzamine; Phosphodiesterase Inhibitors; Radial Artery; Spasm; Time Factors; Treatment Outcome; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins | 2003 |
Endothelin-1 promotes Ca2+ antagonist-insensitive coronary smooth muscle contraction via activation of epsilon-protein kinase C.
Topics: Animals; Calcium; Calcium Channel Blockers; Coronary Vasospasm; Coronary Vessels; Diltiazem; Disease Models, Animal; Drug Resistance; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Naphthalenes; Peptide Fragments; Protein Kinase C; Protein Kinase C-epsilon; Protein Transport; Signal Transduction; Swine; Tetradecanoylphorbol Acetate; Vasoconstriction; Verapamil | 2004 |
Endothelium-derived reactive oxygen species and endothelin-1 attenuate NO-dependent pulmonary vasodilation following chronic hypoxia.
Topics: Animals; Diltiazem; Endothelin-1; Hypoxia; Kinetics; Male; Microcirculation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Potassium Chloride; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spermine; Vasodilation | 2004 |
Effect of voltage-gated and capacitative calcium entry blockade on agonist-induced constriction of equine laminar blood vessels.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Dinoprost; Endothelin-1; Hoof and Claw; Horses; Imidazoles; In Vitro Techniques; Logistic Models; Muscle, Smooth, Vascular; Phenylephrine; Serotonin; Vasoconstriction | 2007 |
Protective effects of hydroxysafflor yellow A on acute and chronic congestive cardiac failure mediated by reducing ET-1, NOS and oxidative stress in rats.
Topics: Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Viscosity; Cardiotonic Agents; Chalcone; Chronic Disease; Coronary Vessels; Creatine Kinase; Diltiazem; Disease Models, Animal; Echocardiography; Endothelin-1; Heart Failure; Hemodynamics; L-Lactate Dehydrogenase; Ligation; Malondialdehyde; Nitric Oxide Synthase; Oxidative Stress; Quinones; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2008 |
Voltage-independent calcium channels mediate lipopolysaccharide-induced hyporeactivity to endothelin-1 in the rat aorta.
Topics: Aminoquinolines; Animals; Aorta, Thoracic; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Diltiazem; Dose-Response Relationship, Drug; Endothelin-1; Lipopolysaccharides; Male; Muscle Proteins; Muscle, Smooth, Vascular; Nifedipine; Organ Culture Techniques; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; rho-Associated Kinases; RNA, Messenger; Time Factors; Vasoconstriction; Vasodilator Agents | 2009 |
Nicotinamide adenine dinucleotide phosphate reduced oxidase 5 (Nox5) regulation by angiotensin II and endothelin-1 is mediated via calcium/calmodulin-dependent, rac-1-independent pathways in human endothelial cells.
Topics: Angiotensin II; Calcium; Calcium Channel Blockers; Calmodulin; Cells, Cultured; Diltiazem; Endothelial Cells; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Inflammation; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidase 5; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proliferating Cell Nuclear Antigen; Pyrones; Quinolines; rac1 GTP-Binding Protein; RNA Interference; RNA, Messenger; Signal Transduction; Superoxides; Time Factors; Vascular Cell Adhesion Molecule-1 | 2010 |
Endothelin-1, but not angiotensin II, induces afferent arteriolar myosin diphosphorylation as a potential contributor to prolonged vasoconstriction.
Topics: Angiotensin II; Animals; Arterioles; Calcium Channel Blockers; Calcium Signaling; Diltiazem; Endothelin A Receptor Antagonists; Endothelin-1; Models, Cardiovascular; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; rho-Associated Kinases; Signal Transduction; Vasoconstriction | 2015 |
Protective effects of diltiazem against vascular endothelial cell injury induced by angiotensin-II and hypoxia.
Topics: Angiotensin II; Animals; Apoptosis; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Cytoprotection; Diltiazem; Disease Models, Animal; Endothelial Cells; Endothelin-1; Humans; Hypoxia; Male; Membrane Potential, Mitochondrial; Mitochondria; Nitric Oxide; Nitric Oxide Synthase Type III; Rats, Wistar; Vascular Diseases | 2015 |
Cardioprotective Effects of Combined Therapy with Hyperbaric Oxygen and Diltiazem Pretreatment on Myocardial Ischemia-Reperfusion Injury in Rats.
Topics: Animals; bcl-2-Associated X Protein; Caspase 3; Combined Modality Therapy; Diltiazem; Disease Models, Animal; Down-Regulation; Endothelin-1; Female; Heart; Hyperbaric Oxygenation; Ischemic Preconditioning; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type III; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Up-Regulation | 2016 |