Page last updated: 2024-08-23

diltiazem and enalaprilat anhydrous

diltiazem has been researched along with enalaprilat anhydrous in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's4 (30.77)18.2507
2000's3 (23.08)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Appenheimer, M; Düsing, R; Graack, GH; Ko, YD; Sachinidis, A; Vetter, H; Wieczorek, AJ1
Bidiville, J; Brunner, HR; Nussberger, J; Porchet, M; Waeber, B; Waeber, G1
Arnaoudov, PI; Latour, C; Nahas, GG; Trouvé, R1
Hintze, TH; Zhang, X1
Dernellis, J; Diamantopoulos, L; Michaelides, A; Stefanadis, C; Toutouzas, P; Tsiamis, E1
Marwood, JF1

Reviews

1 review(s) available for diltiazem and enalaprilat anhydrous

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for diltiazem and enalaprilat anhydrous

ArticleYear
Individual responses to converting enzyme inhibitors and calcium antagonists.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:2

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Enalapril; Enalaprilat; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Random Allocation; Time Factors

1988

Other Studies

11 other study(ies) available for diltiazem and enalaprilat anhydrous

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Inhibition of angiotensin II and platelet-derived growth factor-induced vascular smooth muscle cell proliferation by calcium entry blockers.
    The Clinical investigator, 1992, Volume: 70, Issue:2

    Topics: Angiotensin II; Animals; Calcium Channel Blockers; Cell Division; Cells, Cultured; Diltiazem; DNA Replication; Dose-Response Relationship, Drug; Enalaprilat; Female; Metoprolol; Muscle, Smooth, Vascular; Nifedipine; Platelet-Derived Growth Factor; Rats; Rats, Inbred WKY

1992
Effects of antidotes to cocaine on the deregulation of the baroreflex by the alkaloid.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1996, Volume: 212, Issue:3

    Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Antidotes; Baroreflex; Blood Pressure; Cocaine; Diltiazem; Enalaprilat; Nicardipine; Rats; Rats, Sprague-Dawley

1996
Amlodipine releases nitric oxide from canine coronary microvessels: an unexpected mechanism of action of a calcium channel-blocking agent.
    Circulation, 1998, Feb-17, Volume: 97, Issue:6

    Topics: Amlodipine; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Dogs; Dose-Response Relationship, Drug; Enalaprilat; In Vitro Techniques; Male; Nitric Oxide; Ramipril; Regression Analysis

1998
Assessment of aortic line of elasticity using polynomial regression analysis.
    Circulation, 2000, Apr-18, Volume: 101, Issue:15

    Topics: Aorta; Blood Pressure; Coronary Disease; Data Interpretation, Statistical; Diltiazem; Elasticity; Enalaprilat; Heart Failure; Humans; Hypertension; Regression Analysis; Risk Factors; Vasodilator Agents

2000
Studies on the interactions between the angiotensin converting enzyme inhibitor enalaprilat and calcium antagonists in rats.
    Journal of hypertension, 1996, Volume: 14, Issue:1

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; Cinnarizine; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Enalaprilat; Felodipine; Female; Male; Models, Animal; Models, Cardiovascular; Rats; Rats, Sprague-Dawley; Verapamil

1996