diltiazem has been researched along with digoxin in 98 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 35 (35.71) | 18.7374 |
1990's | 22 (22.45) | 18.2507 |
2000's | 24 (24.49) | 29.6817 |
2010's | 16 (16.33) | 24.3611 |
2020's | 1 (1.02) | 2.80 |
Authors | Studies |
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Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Gupta, D; Gupta, MS | 1 |
Grupp, G; Grupp, I; Heikkila, J; Luomanmaki, K; Pesola, MK; Ramo, MP; Schroder, T | 1 |
Dahlström, CG; Edvardsson, N; Nasheng, C; Olsson, SB | 1 |
Christensen, C | 1 |
Li, QL; Wu, HS; Zhang, JL | 1 |
Zheng, Z | 1 |
Takahashi, H; Yoshimura, M | 1 |
Lewis, RV; McDevitt, DG | 2 |
Larsson, H; Molin, L; Scherling, IL | 1 |
Agretto, A; Auricchio, A; Barbato, F; De Simone, R; De Stefano, R; Iacono, A; Vitale, N; Vitale, P | 1 |
Henry, M; Kay, MM; Viccellio, P | 1 |
Atwood, JE; Forbes, S; Friis, R; Froelicher, V; Myers, J; Pewen, W; Sullivan, M | 1 |
Aupetit, JF; Gallet, M; Lefrançois, JJ; Lestaevel, M; Lopez, M; Manchon, J | 1 |
Irvine, N; Lewis, RV; McDevitt, DG | 1 |
Laing, E; Lewis, RV; McDevitt, DG; Moreland, TA; Service, E | 1 |
Dalla Volta, S; Gaion, RM; Grion, AM; Maragno, I; Miraglia, G; Santostasi, G; Trento, M | 1 |
Eichler, HG; Gasic, S; Korn, A | 1 |
Andrejak, M; Andrejak, MT; Hary, L; Lesbre, JP | 1 |
Taubert, KA | 1 |
Alitto, F; Buja, G; Dalla Volta, S; Gaion, RM; Maragno, I; Miraglia, G; Santostasi, G | 1 |
Beier-Scott, L; Eliastam, M; Schroeder, JS; Sternbach, GL | 1 |
Hiser, WW; Mattern, AL; North, DS | 1 |
Boden, WE; Bough, EW; Korr, KS; More, G; Sharma, S; Shulman, RS; Young, PM | 1 |
Bliss, M; Goldman, S; Jones, WN; Kern, KB; Mayersohn, M; Rindone, JP | 1 |
Bren, GB; Buff, LA; Katz, RJ; Steinberg, JS; Varghese, PJ | 1 |
Jones, EM; Kasmer, RJ | 1 |
Pfeiffer, G | 1 |
Kenny, J | 1 |
Cohen, J; Elkayam, U; Harrison, E; Mitani, G; Rahimtoola, SH; Roth, A | 1 |
Kuhlmann, J | 1 |
Cohen, JL; Elkayam, U; Parikh, K; Rahimtoola, SH; Torkan, B; Weber, L | 1 |
Kuhlmann, J; Marcin, S | 1 |
Aupetit, JF; Gallet, M; Leizorovicz, A; Lopez, M; Manchon, J; Manchon, M | 1 |
Fujita, M; Ito, K; Owada, E; Yoshida, A | 1 |
Arakawa, M; Fujita, M; Fukuda, R; Ito, K; Kurosawa, N; Nioka, M; Owada, E; Shichinohe, T; Yoshida, A | 1 |
Akino, E; Fujii, S; Goto, K; Kanda, K; Kawasaki, H; Nagata, M; Oyama, Y | 1 |
Ganzinger, U; Magometschnigg, D; Rameis, H | 1 |
Fondacaro, JD; Jacobson, ED; Walus, KM | 1 |
Jutzy, KR; Lewis, SJ; Mason, JW; Mitchell, LB; Schroeder, JS | 1 |
Bloedow, DC; Gal, J; Nies, AS; Piepho, RW | 1 |
Decrinis, M; Kasper, K; Schulze-Bauer, C; Stark, G; Stark, U; Tritthart, HA | 2 |
Baik, SH; Cho, SK; Kim, EJ; Kim, SH; Kim, SS; Koh, KK; Kwon, KS; Lee, KH; Park, HB; Park, SJ | 1 |
Shettigar, UR | 1 |
Blackshear, JL; Hammill, SC; Kopecky, SL; Litin, SC; Safford, RE | 1 |
Baik, SH; Cho, SK; In, HH; Koh, KK; Kwon, KS; Moon, TH; Park, GS; Park, HB; Park, YS; Song, JH | 1 |
Gokhroo, RK; Gupta, RP; Mittal, SR | 1 |
Herbert, ME; Rutz, F; Votey, SR | 1 |
Rivera, AR; Schreck, DM; Tricarico, VJ | 1 |
Decrinis, M; Kasper, K; Lindner, W; Schwarzl, I; Stark, G; Stark, U | 1 |
Langan, MN | 1 |
Amar, D; Bains, MS; Burt, ME; Downey, RJ; Ginsberg, RJ; Leung, DH; Roistacher, N; Rusch, VW | 1 |
Bolar-Softich, KL; Elam, K | 1 |
Borzak, S; Frank, DM; Goldberg, AD; Higgins, RS; Padhi, ID; Paone, G; Silverman, NA; Tisdale, JE; Webb, CR | 1 |
Bonini, W; Botto, GL; Broffoni, T | 1 |
Farshi, R; Kistner, D; Longmate, JA; Sarma, JS; Singh, BN | 1 |
Bass, EB; Goodman, SN; Kim, N; McNamara, RL; Miller, MR; Powe, NR; Robinson, K; Segal, JB; Yu, D | 1 |
Cleland, JG; Kaye, GC; Khand, AU; Rankin, AC | 1 |
Arora, P; Khan, IA; Mehta, NJ; Sacchi, TJ; Singh, N; Vasavada, BC; Wattanasuwan, N | 1 |
Abdulatif, AS; El-Medany, AH; Mahgoub, AA | 1 |
Goto, Y; Higuchi, S; Minemoto, M; Ohdo, S; Suematsu, F; Yukawa, E; Yukawa, M | 1 |
Chung, M; Connor, J; Dessoffy, R; Doi, K; Fukamachi, K; Howard, M; Kopcak, M; Mazgalev, TN; McCarthy, PM; Ochiai, Y; Takagaki, M | 1 |
Freestone, B; Kamath, S; Lip, G | 2 |
Burns, M; Dorian, P; Freeman, M; Korley, V; Newman, D; Ng, A; Paquette, M; Pinter, A; Spanu, I | 1 |
Bass, EB; Tamariz, LJ | 1 |
Bauer, A; Donahue, JK; Heldman, AW; McDonald, AD; Miller, JM; Nasir, K; Peller, L; Rade, JJ | 1 |
Freestone, B; Lip, GY | 2 |
Holmes, EC; Samuels, FL; Samuels, LE | 1 |
Cheng, TO | 1 |
Lip, GY | 1 |
Elston Lafata, J; Horn, JR; Kaatz, S; Raebel, MA; Schultz, L; Simpkins, J; Smith, DH; Yood, MU | 1 |
Lam, KF; Lau, CP; Lee, WL; Siu, CW; Tse, HF | 1 |
González Oliva, JC; Pou Potau, M; Ramírez de Arellano Serna, M; Salas Gama, KR; Saurina i Solé, A | 1 |
Globits, S; Hirschl, MM; Wollmann, C | 1 |
Griffiths, LG; Jung, S | 1 |
Drożdż, J; Filipiak, KJ; Grajek, S; Kasprzak, JD; Opolski, G; Rynkiewicz, A; Stępińska, J; Tykarski, A; Wożakowska Kapłon, B | 1 |
Akhtar, MS; Bashir, S; Malik, MN; Manzoor, R | 1 |
Newsome, SD; Probasco, JC; Schneider, L | 1 |
Carroll, C; Hassanin, A | 1 |
Hayes, BD; Roy, N; Sin, JH; Tom, A; Toyoda, A | 1 |
Chang, H; Chen, C; Du, H; Guan, C; Li, C; Qiu, L; Wang, S; Wang, T; Wu, Y; Zhang, L; Zhang, S; Zhou, H | 1 |
16 review(s) available for diltiazem and digoxin
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Interaction between calcium antagonists and digoxin].
Topics: Atrial Fibrillation; Calcium Channel Blockers; Digoxin; Diltiazem; Drug Interactions; Humans; Nifedipine; Verapamil | 1991 |
The central nervous system and effective antihypertensive effects of a calcium channel blocker.
Topics: Animals; Blood Platelets; Blood Proteins; Calcium; Calcium Channel Blockers; Cardenolides; Central Nervous System; Digoxin; Diltiazem; Humans; Hypertension; Hypothalamo-Hypophyseal System; Rats; Rats, Inbred SHR; Saponins; Sodium-Potassium-Exchanging ATPase | 1987 |
Calcium channel blocking agents and the heart.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Vasospasm; Digoxin; Diltiazem; Heart Block; Heart Diseases; Heart Rate; Humans; Hypertension; Nifedipine; Verapamil | 1985 |
Management of rapid ventricular rate in acute atrial fibrillation.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Heart Rate; Humans; Propranolol; Verapamil; Wolff-Parkinson-White Syndrome | 1994 |
Management of atrial fibrillation in adults: prevention of thromboembolism and symptomatic treatment.
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Aspirin; Atrial Fibrillation; Catheter Ablation; Cerebrovascular Disorders; Diabetes Complications; Digoxin; Diltiazem; Embolism; Humans; Hypertension; Thromboembolism; Verapamil; Warfarin | 1996 |
Dilemmas in the acute pharmacologic treatment of uncontrolled atrial fibrillation.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium Channel Blockers; Digoxin; Diltiazem; Emergency Medical Services; Humans; Propanolamines | 1997 |
The evidence regarding the drugs used for ventricular rate control.
Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Bias; Calcium Channel Blockers; Digoxin; Diltiazem; Evidence-Based Medicine; Exercise; Heart Rate; Humans; Research Design; Rest; Treatment Outcome; Ventricular Function; Verapamil | 2000 |
Systematic review of the management of atrial fibrillation in patients with heart failure.
Topics: Acute Disease; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Chronic Disease; Clinical Trials as Topic; Digoxin; Diltiazem; Electric Countershock; Heart Failure; Humans; Retrospective Studies | 2000 |
Acute atrial fibrillation.
Topics: Acute Disease; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Electrocardiography; Fibrinolytic Agents; Humans; Prognosis; Randomized Controlled Trials as Topic; Thromboembolism; Timolol; Treatment Outcome; Verapamil | 2002 |
Pharmacological rate control of atrial fibrillation.
Topics: Amiodarone; Atenolol; Atrial Fibrillation; Cardiotonic Agents; Digoxin; Diltiazem; Heart Rate; Humans; Metoprolol; Randomized Controlled Trials as Topic; Verapamil | 2004 |
Atrial fibrillation (acute).
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Humans; Timolol; Verapamil | 2003 |
Atrial fibrillation (acute).
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Flecainide; Humans; Propafenone; Timolol; Verapamil | 2003 |
Selective use of amiodarone and early cardioversion for postoperative atrial fibrillation.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Coronary Artery Bypass; Digoxin; Diltiazem; Drug Therapy, Combination; Electric Countershock; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Length of Stay; Male; Middle Aged; Postoperative Complications; Procainamide; Retrospective Studies; Treatment Outcome | 2005 |
Atrial fibrillation (acute).
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Flecainide; Humans; Propafenone; Verapamil | 2004 |
Atrial fibrillation (recent onset).
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Flecainide; Humans; Propafenone; Verapamil | 2005 |
21 trial(s) available for diltiazem and digoxin
Article | Year |
---|---|
Effects of diltiazem, propranolol, and their combination in the control of atrial fibrillation.
Topics: Atrial Fibrillation; Digoxin; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Humans; Male; Middle Aged; Propranolol | 1992 |
The relative effects of digoxin and diltiazem upon ventricular ectopic activity in patients with chronic atrial fibrillation.
Topics: Aged; Atrial Fibrillation; Cardiac Complexes, Premature; Chronic Disease; Digoxin; Diltiazem; Female; Humans; Male; Middle Aged | 1988 |
[Effectiveness of diltiazem in controlling ventricular response and improving exercise capacity in chronic atrial fibrillation. Double-blind, cross-over study].
Topics: Atrial Fibrillation; Chronic Disease; Depression, Chemical; Digitalis; Digoxin; Diltiazem; Double-Blind Method; Drug Evaluation; Female; Heart Rate; Heart Ventricles; Humans; Male; Middle Aged; Plants, Medicinal; Plants, Toxic; Random Allocation | 1989 |
Perceived exertion and gas exchange after calcium and beta-blockade in atrial fibrillation.
Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Blood Pressure; Carbon Dioxide; Celiprolol; Chronic Disease; Clinical Trials as Topic; Digoxin; Diltiazem; Double-Blind Method; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Oxygen; Oxygen Consumption; Physical Exertion; Propanolamines; Random Allocation | 1987 |
Factors affecting the clinical response to treatment with digoxin and two calcium antagonists in patients with atrial fibrillation.
Topics: Atrial Fibrillation; Calcium Channel Blockers; Clinical Trials as Topic; Digoxin; Diltiazem; Double-Blind Method; Heart Rate; Humans; Physical Exertion; Random Allocation; Rheumatic Heart Disease; Verapamil | 1988 |
Relationships between heart rate, exercise tolerance and cardiac output in atrial fibrillation: the effects of treatment with digoxin, verapamil and diltiazem.
Topics: Aged; Atrial Fibrillation; Cardiac Output; Chronic Disease; Digoxin; Diltiazem; Heart Rate; Humans; Middle Aged; Physical Exertion; Verapamil | 1988 |
A comparison of digoxin, diltiazem and their combination in the treatment of atrial fibrillation.
Topics: Aged; Atrial Fibrillation; Chronic Disease; Clinical Trials as Topic; Digoxin; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Random Allocation | 1988 |
Low- and medium-dose diltiazem in chronic atrial fibrillation: comparison with digoxin and correlation with drug plasma levels.
Topics: Adult; Aged; Atrial Fibrillation; Blood Pressure; Chronic Disease; Digoxin; Diltiazem; Drug Therapy, Combination; Electrocardiography; Female; Heart Rate; Humans; Male; Middle Aged; Physical Exertion | 1988 |
[Simultaneous administration of digoxin and diltiazem in patients with cardiac insufficiency and coronary heart disease].
Topics: Aged; Benzazepines; Bradycardia; Clinical Trials as Topic; Coronary Disease; Digoxin; Diltiazem; Drug Therapy, Combination; Female; Heart Failure; Humans; Male; Placebos | 1985 |
The diltiazem-digoxin interaction.
Topics: Adult; Benzazepines; Digoxin; Diltiazem; Drug Interactions; Humans; Kinetics; Male; Metabolic Clearance Rate; Protein Binding | 1984 |
Efficacy and safety of digoxin alone and in combination with low-dose diltiazem or betaxolol to control ventricular rate in chronic atrial fibrillation.
Topics: Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Betaxolol; Chronic Disease; Digoxin; Diltiazem; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Prospective Studies; Ventricular Function | 1995 |
Comparative study of efficacy and safety of low-dose diltiazem or betaxolol in combination with digoxin to control ventricular rate in chronic atrial fibrillation: randomized crossover study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Betaxolol; Blood Pressure; Calcium Channel Blockers; Chronic Disease; Cross-Over Studies; Digoxin; Diltiazem; Drug Therapy, Combination; Exercise Tolerance; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Prospective Studies; Ventricular Dysfunction, Left | 1995 |
Emergency management of atrial fibrillation and flutter: intravenous diltiazem versus intravenous digoxin.
Topics: Acute Disease; Aged; Aged, 80 and over; Analysis of Variance; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Digoxin; Diltiazem; Emergency Medical Services; Female; Heart Rate; Humans; Infusions, Intravenous; Male; Middle Aged; Prospective Studies; Treatment Outcome | 1997 |
Effects of diltiazem versus digoxin on dysrhythmias and cardiac function after pneumonectomy.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Digoxin; Diltiazem; Echocardiography, Doppler; Female; Heart; Humans; Lung Neoplasms; Male; Middle Aged; Pleural Neoplasms; Pneumonectomy; Prospective Studies; Treatment Outcome; Ventricular Pressure | 1997 |
A randomized, double-blind comparison of intravenous diltiazem and digoxin for atrial fibrillation after coronary artery bypass surgery.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Digoxin; Diltiazem; Double-Blind Method; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Infusions, Intravenous; Male; Middle Aged; Postoperative Complications; Treatment Outcome; Vasodilator Agents | 1998 |
Modulation of ventricular rate in permanent atrial fibrillation: randomized, crossover study of the effects of slow-release formulations of gallopamil, diltiazem, or verapamil.
Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium Channel Blockers; Cardiotonic Agents; Cross-Over Studies; Delayed-Action Preparations; Digoxin; Diltiazem; Electrocardiography, Ambulatory; Female; Gallopamil; Heart Rate; Humans; Male; Middle Aged; Verapamil | 1998 |
Ventricular rate control in chronic atrial fibrillation during daily activity and programmed exercise: a crossover open-label study of five drug regimens.
Topics: Aged; Anti-Arrhythmia Agents; Atenolol; Atrial Fibrillation; Calcium Channel Blockers; Circadian Rhythm; Cross-Over Studies; Digoxin; Diltiazem; Drug Therapy, Combination; Electrocardiography, Ambulatory; Exercise; Female; Follow-Up Studies; Heart Rate; Heart Ventricles; Humans; Male; Middle Aged | 1999 |
Acute ventricular rate control in atrial fibrillation: IV combination of diltiazem and digoxin vs. IV diltiazem alone.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Cardiovascular Agents; Digoxin; Diltiazem; Drug Therapy, Combination; Female; Heart Rate; Humans; Male; Middle Aged; Prospective Studies | 2001 |
A comparison between the effects of diltiazem and isosorbide dinitrate on digoxin pharmacodynamics and kinetics in the treatment of patients with chronic ischemic heart failure.
Topics: Analysis of Variance; Digoxin; Diltiazem; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Electrolytes; Enzyme Inhibitors; Female; Half-Life; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Ischemia; Vasodilator Agents | 2002 |
Left ventricular performance during acute rate control in atrial fibrillation: the importance of heart rate and agent used.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Blood Pressure; Cardiac Output; Digoxin; Diltiazem; Female; Heart Rate; Humans; Injections, Intravenous; Male; Middle Aged; Single-Blind Method; Stroke Volume; Time Factors | 2003 |
Intravenous diltiazem is superior to intravenous amiodarone or digoxin for achieving ventricular rate control in patients with acute uncomplicated atrial fibrillation.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Studies; Digoxin; Diltiazem; Female; Humans; Infusions, Intravenous; Length of Stay; Male; Middle Aged; Tachycardia, Ventricular; Treatment Outcome | 2009 |
61 other study(ies) available for diltiazem and digoxin
Article | Year |
---|---|
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Diltiazem as adjunctive oral therapy in patients with chronic atrial fibrillation.
Topics: Administration, Oral; Aged; Atrial Fibrillation; Chronic Disease; Digoxin; Diltiazem; Drug Therapy, Combination; Exercise; Female; Heart Rate; Humans; Male; Middle Aged | 1992 |
Cardiac glycosides in the treatment of experimental overdose with calcium-blocking agents.
Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Calcium Gluconate; Depression, Chemical; Digoxin; Diltiazem; Dogs; Drug Overdose; Electrocardiography; Female; Hemodynamics; Humans; Male; Myocardium; Verapamil | 1992 |
[Effect of combined treatment of diltiazem and digoxin on serum digoxin concentration].
Topics: Adult; Digoxin; Diltiazem; Drug Therapy, Combination; Female; Heart Failure; Humans; Male; Middle Aged | 1990 |
[The use of digoxin and diltiazem in controlling ventricular rate in chronic atrial fibrillation].
Topics: Adult; Atrial Fibrillation; Depression, Chemical; Digoxin; Diltiazem; Drug Therapy, Combination; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Male; Middle Aged | 1990 |
No significant in vitro interference of diltiazem and metabolites in digoxin radioimmunoassay (four assay methods).
Topics: Digoxin; Diltiazem; Drug Therapy, Combination; Humans; Radioimmunoassay; Random Allocation | 1989 |
Cardiogenic shock associated with calcium-channel and beta blockers: reversal with intravenous calcium chloride.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Calcium Channel Blockers; Calcium Chloride; Digoxin; Diltiazem; Female; Humans; Isoproterenol; Male; Shock, Cardiogenic; Verapamil | 1985 |
[Diltiazem and digoxin interaction. Development of digoxin plasma levels and electrocardiographic parameters in healthy subjects].
Topics: Adult; Digoxin; Diltiazem; Drug Interactions; Electrocardiography; Female; Heart; Heart Rate; Humans; Male | 1986 |
Diltiazem counteracts digitalis-dependent splanchnic vasoconstriction in man.
Topics: Adult; Blood Pressure; Cardiac Output; Digoxin; Diltiazem; Heart Rate; Humans; Infusions, Intravenous; Liver; Male; Splanchnic Circulation; Vascular Resistance; Vasoconstriction | 1987 |
Diltiazem increases steady state digoxin serum levels in patients with cardiac disease.
Topics: Adult; Aged; Aged, 80 and over; Creatinine; Digoxin; Diltiazem; Drug Interactions; Female; Heart Diseases; Heart Rate; Humans; Male; Middle Aged | 1987 |
Tissue distribution of digoxin in the presence of calcium channel blockers.
Topics: Animals; Calcium Channel Blockers; Digoxin; Diltiazem; Guinea Pigs; Male; Tissue Distribution; Verapamil | 1987 |
[Efficacy of diltiazem in the control of ventricular frequency in chronic atrial fibrillation].
Topics: Adult; Aged; Atrial Fibrillation; Blood Pressure; Chronic Disease; Digoxin; Diltiazem; Female; Heart Rate; Humans; Male; Middle Aged | 1987 |
Intravenous diltiazem for the treatment of supraventricular tachycardia.
Topics: Adult; Atrioventricular Node; Benzazepines; Blood Pressure; Digoxin; Diltiazem; Female; Heart Rate; Humans; Infusions, Parenteral; Male; Middle Aged; Tachycardia, Paroxysmal; Verapamil | 1986 |
The influence of diltiazem hydrochloride on trough serum digoxin concentrations.
Topics: Adult; Benzazepines; Digoxin; Diltiazem; Drug Interactions; Female; Humans; Male | 1986 |
No increase in serum digoxin concentration with high-dose diltiazem.
Topics: Benzazepines; Digoxin; Diltiazem; Drug Administration Schedule; Female; Heart Rate; Humans; Male | 1986 |
Digoxin-diltiazem interaction: a pharmacokinetic evaluation.
Topics: Adult; Digoxin; Diltiazem; Drug Interactions; Half-Life; Humans; Kinetics; Male; Regression Analysis | 1986 |
Efficacy of oral diltiazem to control ventricular response in chronic atrial fibrillation at rest and during exercise.
Topics: Adult; Aged; Atrial Fibrillation; Digoxin; Diltiazem; Drug Evaluation; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Physical Exertion; Rest; Tachycardia, Supraventricular | 1987 |
Diltiazem-nifedipine-digoxin interaction.
Topics: Aged; Digoxin; Diltiazem; Drug Interactions; Humans; Male; Nifedipine | 1986 |
Efficacy and safety of medium- and high-dose diltiazem alone and in combination with digoxin for control of heart rate at rest and during exercise in patients with chronic atrial fibrillation.
Topics: Adult; Atrial Fibrillation; Benzazepines; Blood Pressure; Digoxin; Diltiazem; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Rest | 1986 |
Effects of nifedipine and diltiazem on plasma levels and renal excretion of beta-acetyldigoxin.
Topics: Acetyldigoxins; Aged; Benzazepines; Digoxin; Diltiazem; Drug Therapy, Combination; Female; Heart Failure; Humans; Kinetics; Male; Middle Aged; Nifedipine | 1985 |
Effect of diltiazem on renal clearance and serum concentration of digoxin in patients with cardiac disease.
Topics: Adult; Aged; Arrhythmias, Cardiac; Benzazepines; Cross Reactions; Digoxin; Diltiazem; Female; Heart Failure; Humans; Kidney; Male; Middle Aged; Radioimmunoassay | 1985 |
[Pharmacokinetic and cardiac efficacy of beta-acetyldigoxin and digitoxin in combination therapy with diltiazem].
Topics: Acetyldigoxins; Aged; Benzazepines; Blood Pressure; Digitoxin; Digoxin; Diltiazem; Drug Therapy, Combination; Electrocardiography; Female; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Pulse | 1985 |
[Effect of diltiazem on the serum concentrations of digoxin].
Topics: Adult; Benzazepines; Digoxin; Diltiazem; Drug Interactions; Female; Humans; Male | 1984 |
Effects of diltiazem on plasma and tissue digoxin levels in mice.
Topics: Animals; Benzazepines; Blood Proteins; Digoxin; Diltiazem; Drug Interactions; Male; Mice; Mice, Inbred Strains; Protein Binding; Quinidine | 1984 |
Effects of diltiazem on plasma level and urinary excretion of digoxin in healthy subjects.
Topics: Absorption; Administration, Oral; Adult; Benzazepines; Chromatography, Gas; Digoxin; Diltiazem; Drug Interactions; Female; Humans; Kinetics; Male | 1984 |
Digoxin-diltiazem interaction.
Topics: Atrial Fibrillation; Benzazepines; Digoxin; Diltiazem; Drug Interactions; Humans | 1984 |
Effects of calcium and its antagonists on the canine mesenteric circulation.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Calcium; Calcium Chloride; Digoxin; Diltiazem; Dogs; Dose-Response Relationship, Drug; Egtazic Acid; Female; Male; Mesenteric Arteries; Muscle Contraction; Nifedipine; Norepinephrine; Salts; Splanchnic Circulation | 1981 |
Intracardiac electrophysiologic study of intravenous diltiazem and combined diltiazem-digoxin in patients.
Topics: Adult; Atrioventricular Node; Benzazepines; Coronary Disease; Digoxin; Diltiazem; Drug Therapy, Combination; Electrocardiography; Female; Heart; Humans; Male; Middle Aged; Sinoatrial Node | 1982 |
Serum binding of diltiazem in humans.
Topics: Adult; Benzazepines; Binding, Competitive; Blood Proteins; Dialysis; Digoxin; Diltiazem; Female; Humans; Male; Propranolol; Protein Binding | 1982 |
Comparison of the frequency-dependent effects on the atrioventricular node of verapamil, amiodarone, digoxin, and diltiazem in isolated guinea pig hearts.
Topics: Amiodarone; Animals; Atrioventricular Node; Cardiac Pacing, Artificial; Computer Simulation; Digoxin; Diltiazem; Electric Stimulation; Electrocardiography; Female; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male; Verapamil | 1995 |
Efficacy of oral diltiazem and digoxin alone and in combination in chronic atrial fibrillation.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium Channel Blockers; Digoxin; Diltiazem; Drug Therapy, Combination; Humans; Prospective Studies | 1995 |
New treatment of atrial fibrillation.
Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Calcium Channel Blockers; Digoxin; Diltiazem; Drug Therapy, Combination; Emergency Medicine; Heart Failure; Humans; Propanolamines; Verapamil | 1996 |
How to measure AV nodal refractoriness in the presence of verapamil, amiodarone, digoxin, and diltiazem.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Cardiac Pacing, Artificial; Digoxin; Diltiazem; Electrocardiography; Female; Fourier Analysis; Guinea Pigs; Heart Rate; Male; Signal Processing, Computer-Assisted; Verapamil | 1996 |
Quantification of rate-dependent effects of verapamil, diltiazem, and digoxin on atrioventricular conduction.
Topics: Adaptation, Physiological; Animals; Atrioventricular Node; Calcium Channel Blockers; Digoxin; Diltiazem; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Sinoatrial Node; Time Factors; Verapamil | 1996 |
The acute treatment of supraventricular tachycardia.
Topics: Acute Disease; Adenosine; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Calcium Channel Blockers; Catheter Ablation; Digoxin; Diltiazem; Electrocardiography; Humans; Tachycardia, Supraventricular | 1997 |
Pharmacoepidemiologic detection of calcium channel blocker-induced change on digoxin clearance using multiple trough screen analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Calcium Channel Blockers; Creatinine; Digoxin; Diltiazem; Drug Interactions; Female; Heart Failure; Humans; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Models, Statistical; Nifedipine; Pharmacoepidemiology; Regression Analysis; Reproducibility of Results; Spironolactone; Verapamil | 2002 |
Preload-adjusted maximal power: a novel index of left ventricular contractility in atrial fibrillation.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiovascular Agents; Digoxin; Diltiazem; Myocardial Contraction; Sheep; Ventricular Function, Left | 2002 |
Inhibitory G protein overexpression provides physiologically relevant heart rate control in persistent atrial fibrillation.
Topics: Acute Disease; Adenoviridae; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrioventricular Node; Cardiac Pacing, Artificial; Digoxin; Diltiazem; Gene Expression Regulation; Genetic Therapy; Genetic Vectors; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Heart Failure; Heart Rate; Propanolamines; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Stroke Volume; Sus scrofa; Ultrasonography | 2004 |
Pseudo-cardioversion of atrial fibrillation.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Heart Rate; Humans; Infusions, Intravenous; Remission, Spontaneous | 2005 |
What do medical records tell us about potentially harmful co-prescribing?
Topics: Adult; Ambulatory Care; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Anticoagulants; Antihypertensive Agents; Digoxin; Diltiazem; Drug Interactions; Drug Utilization Review; Health Maintenance Organizations; Humans; Lovastatin; Medical Audit; Medication Errors; Office Visits; Polypharmacy; United States; Verapamil; Warfarin | 2007 |
[Difficult-to-treat atrial fibrillation in a patient on haemodialysis].
Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Atrial Fibrillation; Bisoprolol; Bradycardia; Calcium Channel Blockers; Cardiovascular Agents; Combined Modality Therapy; Digoxin; Diltiazem; Female; Humans; Hypothyroidism; Kidney Failure, Chronic; Myocardial Infarction; Pacemaker, Artificial; Renal Dialysis | 2010 |
A 2-year survey of treatment of acute atrial fibrillation in an ED.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Emergency Service, Hospital; Female; Flecainide; Humans; Male; Middle Aged; Sulfonamides; Time Factors; Treatment Outcome | 2011 |
ECG of the Month. Atrial fibrillation.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Dog Diseases; Dogs; Electrocardiography; Female | 2011 |
[Optimum heart rate - the current goal of cardiovascular therapy. Position statement of the Polish Cardiac Society Working Group on Cardiovascular Drug Therapy].
Topics: Adrenergic beta-Agonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Digoxin; Diltiazem; Heart Diseases; Heart Rate; Humans; Hypertension; Ivabradine; Verapamil | 2012 |
Cardiotonic activity of methanolic extract of Saussurea lappa Linn roots.
Topics: Animals; Cardiotonic Agents; Digoxin; Diltiazem; Female; Male; Plant Extracts; Plant Roots; Rabbits; Saussurea | 2013 |
Clinical reasoning: A 68-year-old man with a first presentation of status epilepticus.
Topics: Aged; Digoxin; Diltiazem; Humans; Male; Risk Factors; Scopolamine Derivatives; Status Epilepticus; Tiotropium Bromide | 2014 |
Polypharmacy in the Elderly-When Good Drugs Lead to Bad Outcomes: A Teachable Moment.
Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Antihypertensive Agents; Atorvastatin; Atrial Fibrillation; Bone Density Conservation Agents; Deprescriptions; Digoxin; Diltiazem; Diuretics; Drug Overdose; Factor Xa Inhibitors; Female; Furosemide; Heart Failure; Histamine H1 Antagonists, Non-Sedating; Histamine H2 Antagonists; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ibandronic Acid; Lisinopril; Loratadine; Metoprolol; Polypharmacy; Pyrazoles; Pyridones; Ranitidine; Syncope | 2017 |
High-dose intravenous lipid emulsion affecting successful initiation of continuous venovenous hemofiltration and extracorporeal membrane oxygenation.
Topics: Alprazolam; Antidotes; Digoxin; Diltiazem; Extracorporeal Membrane Oxygenation; Fat Emulsions, Intravenous; Fatal Outcome; Female; Hemofiltration; Humans; Middle Aged; Multiple Organ Failure; Poisoning | 2018 |
Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats.
Topics: Animals; Antipyrine; Atenolol; Carbamazepine; Cell Membrane; Digoxin; Diltiazem; Diphenhydramine; Drug Elimination Routes; Gabapentin; Lamotrigine; Liver; Memantine; Membrane Transport Proteins; Microdialysis; Muscle, Skeletal; Ofloxacin; Pharmaceutical Preparations; Propranolol; Pyrilamine; Quinidine; Rats; Terfenadine | 2021 |