Page last updated: 2024-08-23

diltiazem and cyclic gmp

diltiazem has been researched along with cyclic gmp in 63 studies

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-19909 (14.29)18.7374
1990's30 (47.62)18.2507
2000's17 (26.98)29.6817
2010's6 (9.52)24.3611
2020's1 (1.59)2.80

Authors

AuthorsStudies
Kobayashi, A; Ogawa, K1
Haynes, LW1
Farrugia, G; Rae, JL1
Falk, G; Shiells, RA1
Matthews, HR; McLatchie, LM2
Nicol, GD; Quandt, FN; Schnetkamp, PP1
Schnetkamp, PP1
Bühler, FR; Kiowski, W; Linder, L1
Bennett, N; Ildefonse, M1
Holcombe, V; Hurwitz, R1
Akatsuka, N; Hara, K; Kurokawa, K; Ochiai, M; Ohno, M; Taguchi, J1
Cook, NJ; Kaupp, UB; Koch, KW1
Bennett, N; Chapron, Y; Clerc, A; Crouzy, S; Ildefonse, M1
MacLeish, PR; Stern, JH1
Hayaishi, O; Miwa, N; Sugino, H; Ueno, R1
Kaupp, UB; MacLeish, PR; Stern, JH1
Miller, RC; Schoeffter, P1
Knutsson, H; MacLeish, PR; Stern, JH1
Abe, K; Adachi, I; Fujiki, H; Kimura, S; Nagasaki, K; Yamaguchi, K1
Kim, P; Kirino, T; Sasaki, T; Takakura, K; Yoshimoto, Y1
Barnes, S; Kurenny, DE; Moroz, LL; Sharkey, KA; Turner, RW1
Holtzclaw, L; Klein, DC; Rodriguez, IR; Russell, JT; Schaad, NC; Vanecek, J1
Korenbrot, JI; Picones, A1
Ahamed, B; Chen, TY; Dhallan, RS; Peng, YW; Reed, RR; Yau, KW1
Clarke, W; Cohen, AH; Fouty, B; Hanson, K; McMurty, IF; Morris, K; Rodman, DM1
Nagao, T; Ohashi, K; Yamazaki, J1
Gotow, T; Murakami, M; Nishi, T1
Hirashima, O; Kawano, H; Kugiyama, K; Motoyama, T; Ohgushi, M; Sugiyama, S; Yasue, H1
Ciampolillo, F; Green, RB; Stanton, BA; Vandorpe, DH1
Bucossi, G; Nizzari, M; Torre, V1
Gomez, MP; Nasi, E1
Katusic, ZS; Onoue, H1
Hensel, M; Kox, WJ; Mäding, K; Volk, T1
Grunwald, ME; Yau, KW; Yu, HH; Yu, WP1
Hackos, DH; Korenbrot, JI1
Duszyk, M; Thethi, K1
Hoshino, T; Kikkawa, K; Murata, S; Yamauchi-Kohno, R1
Dreyfus, H; Fabre, M; Frasson, M; Picaud, S; Sahel, JA; Simonutti, M1
He, Y; Karpen, JW; Ruiz, M1
Biel, M; Gerstner, A; Hofmann, F; Zong, X1
Bennett, N; Crouzy, S; Ildefonse, M; Pagès, F; Ragno, M1
Doi, H; Ikeo, T; Karasawa, T; Katoh, M; Narita, H; Odawara, A; Takagi, M1
Folkesson, HG; Guggino, SE; Lu, LN; Matthay, MA; Norlin, A1
Charles, A; Costantin, J; Weiner, R1
Kim, W; Lee, HM; Park, CS; Park, YS1
Akaishi, Y; Hattori, Y; Kitabatake, A; Sakuma, I; Sato, A; Tomioka, H1
Townes-Anderson, E; Zhang, N1
Peng, C; Rich, ED; Varnum, MD2
Costa, G; García-Pascual, A; González, M; Triguero, D1
Fabczak, H; Fabczak, S; Walerczyk, M1
Barki-Harrington, L; Rimon, G; Shalom, R1
Cao, LH; Choi, DH; Kang, DG; Kim, JS; Kim, SJ; Lee, H; Lee, HS; Lee, JK1
Akimoto, Y; Daida, H; Suzuki, H; Yokoyama, K1
Feng, Z; Liu, J; Ward, A; Xu, XZ1
Cheng, KT; Huang, Y; Kwan, HY; Ma, Y; Tang, NL; Yao, X; Yu, S1
Horikoshi, T; Pankey, S; Sakakibara, M; Sunada, H1
Cocco, S; D'Ascenzo, M; Grassi, C; Leone, L; Mezzogori, D; Piacentini, R; Podda, MV1
Liu, C; Sherpa, T; Varnum, MD1
Cisneros-Mejorado, A; Hernández-Soberanis, L; Islas-Carbajal, MC; Sánchez, D1
Blood, AB; Liu, T; Longo, LD; Power, GG; Schroeder, HJ; Terry, MH; Wilson, SM; Zhang, M1
Achury, M; Das, S; Euler, T; Groeneveld, K; Melle, C; Nache, V; Paquet-Durand, F; Popp, V; Power, M; Rogerson, L; Schwede, F; Strasser, T; Yan, J1

Other Studies

63 other study(ies) available for diltiazem and cyclic gmp

ArticleYear
Effects of coronary vasodilator on cyclic nucleotides. The concentrations of cyclic AMP and cyclic GMP in canine coronary artery and left ventricular muscle following the administration of various coronary vasodilators.
    Japanese circulation journal, 1979, Volume: 43 Suppl 1

    Topics: Amyl Nitrite; Animals; Coronary Vessels; Cyclic AMP; Cyclic GMP; Diltiazem; Dipyridamole; Dogs; Heart Ventricles; Isosorbide Dinitrate; Myocardium; Nifedipine; Nitroglycerin; Papaverine; Radioimmunoassay; Vasodilator Agents

1979
Block of the cyclic GMP-gated channel of vertebrate rod and cone photoreceptors by l-cis-diltiazem.
    The Journal of general physiology, 1992, Volume: 100, Issue:5

    Topics: Animals; Binding Sites; Cell Membrane; Cyclic GMP; Cytoplasm; Diltiazem; Dose-Response Relationship, Drug; Ictaluridae; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kinetics; Membrane Potentials; Photoreceptor Cells

1992
Regulation of a potassium-selective current in rabbit corneal epithelium by cyclic GMP, carbachol and diltiazem.
    The Journal of membrane biology, 1992, Volume: 129, Issue:1

    Topics: Animals; Calcium; Carbachol; Cornea; Cyclic GMP; Diltiazem; Epithelium; Ion Channel Gating; Potassium Channels; Rabbits; Second Messenger Systems

1992
Properties of the cGMP-activated channel of retinal on-bipolar cells.
    Proceedings. Biological sciences, 1992, Jan-22, Volume: 247, Issue:1318

    Topics: Aminobutyrates; Animals; Calcium; Cations, Divalent; Cesium; Chlorides; Cyclic GMP; Dendrites; Diltiazem; Dogfish; Egtazic Acid; In Vitro Techniques; Magnesium; Membrane Potentials; Photoreceptor Cells; Retina; Synapses

1992
Voltage-dependent block by L-cis-diltiazem of the cyclic GMP-activated conductance of salamander rods.
    Proceedings. Biological sciences, 1992, Feb-22, Volume: 247, Issue:1319

    Topics: Ambystoma; Animals; Cyclic GMP; Diltiazem; Electric Conductivity; In Vitro Techniques; Kinetics; Membrane Potentials; Photoreceptor Cells

1992
Voltage-dependent gating and block of the cyclic-GMP-dependent current in bovine rod outer segments.
    Neuroscience, 1991, Volume: 42, Issue:3

    Topics: Animals; Calcium; Calcium Channels; Cattle; Cyclic GMP; Diltiazem; Ion Channel Gating; Membrane Potentials; Rod Cell Outer Segment; Second Messenger Systems; Tetracaine

1991
Cation selectivity of and cation binding to the cGMP-dependent channel in bovine rod outer segment membranes.
    The Journal of general physiology, 1990, Volume: 96, Issue:3

    Topics: Animals; Biological Transport, Active; Cations; Cattle; Cyclic GMP; Diltiazem; In Vitro Techniques; Intracellular Membranes; Ion Channels; Kinetics; Neutral Red; Rod Cell Outer Segment; Sodium; Tetracaine

1990
Arterial vasodilator and antihypertensive effects of diltiazem.
    Journal of cardiovascular pharmacology, 1990, Volume: 16 Suppl 6

    Topics: Adult; Antihypertensive Agents; Cyclic GMP; Diltiazem; Humans; Hypertension; Male; Middle Aged; Nitroprusside; Vasodilator Agents

1990
Single-channel study of the cGMP-dependent conductance of retinal rods from incorporation of native vesicles into planar lipid bilayers.
    The Journal of membrane biology, 1991, Volume: 123, Issue:2

    Topics: Animals; Calcium; Cattle; Cobalt; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Electric Conductivity; GTP-Binding Proteins; Ion Channels; Lipid Bilayers; Magnesium; Membrane Potentials; Photoreceptor Cells; Silver; Tetracaine

1991
Affinity purification of the photoreceptor cGMP-gated cation channel.
    The Journal of biological chemistry, 1991, May-05, Volume: 266, Issue:13

    Topics: Animals; Blotting, Western; Cattle; Chromatography, Affinity; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Electrophoresis, Polyacrylamide Gel; Eye Proteins; Ion Channels; Photoreceptor Cells; Trypsin

1991
Stretch may enhance the release of endothelium-derived relaxing factor in rabbit aorta.
    Biochemical and biophysical research communications, 1990, Dec-31, Volume: 173, Issue:3

    Topics: Animals; Aorta; Calcium; Calcium Channels; Cyclic GMP; Diltiazem; Endothelium, Vascular; Male; Nicardipine; Nitric Oxide; Physical Stimulation; Rabbits; Radioimmunoassay

1990
The cGMP-dependent channel of vertebrate rod photoreceptors exists in two forms of different cGMP sensitivity and pharmacological behavior.
    The Journal of biological chemistry, 1987, Oct-25, Volume: 262, Issue:30

    Topics: Animals; Calcium; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Ion Channels; Kinetics; Photoreceptor Cells; Rod Cell Outer Segment

1987
Direct activation of cGMP-dependent channels of retinal rods by the cGMP phosphodiesterase.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:10

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cattle; Cyclic GMP; Diltiazem; Electric Conductivity; GTP-Binding Proteins; In Vitro Techniques; Ion Channels; Membrane Potentials; Molecular Weight; Photoreceptor Cells; Sodium

1989
Direct effects of divalent cations and cyclic GMP on excised patches of rod outer segment membrane.
    Neuroscience research. Supplement : the official journal of the Japan Neuroscience Society, 1987, Volume: 6

    Topics: Ambystoma; Animals; Cations, Divalent; Cell Membrane; Cyclic GMP; Diltiazem; In Vitro Techniques; Membrane Potentials; Photoreceptor Cells; Subcellular Fractions

1987
Prostaglandin induces Ca2+ influx and cyclic GMP formation in mouse neuroblastoma X rat glioma hybrid NG108-15 cells in culture.
    Journal of neurochemistry, 1988, Volume: 50, Issue:5

    Topics: Aminoquinolines; Animals; Calcium; Cyclic GMP; Diltiazem; Dinoprost; Dinoprostone; Fluorescent Dyes; Glioma; Hybrid Cells; Kinetics; Mice; Neuroblastoma; Nifedipine; Potassium; Prostaglandin D2; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Rats; Tumor Cells, Cultured; Verapamil

1988
Control of the light-regulated current in rod photoreceptors by cyclic GMP, calcium, and l-cis-diltiazem.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:4

    Topics: Ambystoma; Animals; Benzazepines; Calcium; Cyclic GMP; Depression, Chemical; Diltiazem; Electrophysiology; Extracellular Space; Intracellular Fluid; Membrane Potentials; Models, Neurological; Photic Stimulation; Photoreceptor Cells; Rod Cell Outer Segment

1986
Role of sodium-calcium exchange and effects of calcium entry blockers on endothelial-mediated responses in rat isolated aorta.
    Molecular pharmacology, 1986, Volume: 30, Issue:1

    Topics: Amiloride; Animals; Aorta; Bepridil; Calcium; Calcium Channel Blockers; Choline; Cyclic GMP; Diltiazem; Endothelium; Female; Lithium; Muscle, Smooth, Vascular; Nicergoline; Nifedipine; Pyrrolidines; Rats; Rats, Inbred Strains; Reserpine; Sodium; Verapamil

1986
Divalent cations directly affect the conductance of excised patches of rod photoreceptor membrane.
    Science (New York, N.Y.), 1987, Jun-26, Volume: 236, Issue:4809

    Topics: Animals; Calcium; Cations, Divalent; Cations, Monovalent; Cyclic GMP; Diltiazem; Electric Conductivity; In Vitro Techniques; Light; Magnesium; Membrane Potentials; Permeability; Photoreceptor Cells; Salamandra

1987
Stimulation of hepatic glycogenolysis by 12-O-tetradecanoylphorbol-13-acetate (TPA) via a calcium requiring process.
    Biochemical and biophysical research communications, 1984, Aug-16, Volume: 122, Issue:3

    Topics: Animals; Calcimycin; Calcium Chloride; Cyclic AMP; Cyclic GMP; Diltiazem; Glucose; Kinetics; Liver; Liver Glycogen; Male; Phorbols; Proteins; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Trifluoperazine; Verapamil

1984
Functional changes in cultured strips of canine cerebral arteries after prolonged exposure to oxyhemoglobin.
    Journal of neurosurgery, 1995, Volume: 83, Issue:5

    Topics: Analysis of Variance; Animals; Basilar Artery; Calcium; Calcium Channel Blockers; Compliance; Cyclic GMP; Diltiazem; Dogs; Female; Ischemic Attack, Transient; Male; Muscle Contraction; Nitric Oxide; Organ Culture Techniques; Oxyhemoglobins; Potassium; Subarachnoid Hemorrhage; Uridine Triphosphate; Vasoconstriction; Vasodilation

1995
Modulation of ion channels in rod photoreceptors by nitric oxide.
    Neuron, 1994, Volume: 13, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Calcium Channels; Cyclic GMP; Cysteine; Diltiazem; Ion Channel Gating; Magnesium; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Retinal Rod Photoreceptor Cells; S-Nitrosothiols; Urodela

1994
Vasoactive intestinal peptide elevates pinealocyte intracellular calcium concentrations by enhancing influx: evidence for involvement of a cyclic GMP-dependent mechanism.
    Molecular pharmacology, 1995, Volume: 47, Issue:5

    Topics: Animals; Calcium; Cells, Cultured; Cyclic GMP; Diltiazem; Extracellular Space; Intracellular Fluid; Ion Channels; Ion Transport; Norepinephrine; Nucleotides, Cyclic; Penicillamine; Pineal Gland; Rats; Receptors, Vasoactive Intestinal Peptide; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Vasoactive Intestinal Peptide

1995
Spontaneous, ligand-independent activity of the cGMP-gated ion channels in cone photoreceptors of fish.
    The Journal of physiology, 1995, Jun-15, Volume: 485 ( Pt 3)

    Topics: Animals; Bass; Calcium; Cell Membrane; Cell Membrane Permeability; Cyclic GMP; Cytoplasm; Diltiazem; In Vitro Techniques; Ion Channel Gating; Patch-Clamp Techniques; Phosphoric Diester Hydrolases; Retinal Cone Photoreceptor Cells

1995
A new subunit of the cyclic nucleotide-gated cation channel in retinal rods.
    Nature, 1993, Apr-22, Volume: 362, Issue:6422

    Topics: Adult; Alternative Splicing; Amino Acid Sequence; Animals; Cell Line; Cloning, Molecular; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Electrochemistry; Eye Proteins; Humans; Immunoenzyme Techniques; Ion Channel Gating; Ion Channels; Molecular Sequence Data; Rod Cell Outer Segment; Sequence Alignment; Transfection; Xenopus

1993
The effect of pH on the block by L-cis-diltiazem and amiloride of the cyclic GMP-activated conductance of salamander rods.
    Proceedings. Biological sciences, 1994, Mar-22, Volume: 255, Issue:1344

    Topics: Ambystoma; Amiloride; Animals; Cyclic GMP; Cytoplasm; Diltiazem; Electric Conductivity; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Membrane Potentials; Retinal Rod Photoreceptor Cells; Rod Cell Outer Segment; Time Factors

1994
Inhibition of cyclic 3'-5'-guanosine monophosphate-specific phosphodiesterase selectively vasodilates the pulmonary circulation in chronically hypoxic rats.
    The Journal of clinical investigation, 1996, Jan-01, Volume: 97, Issue:1

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calcium Channel Blockers; Cyclic GMP; Diltiazem; Hemodynamics; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; Nitric Oxide; Perfusion; Phosphodiesterase Inhibitors; Piperidines; Pulmonary Circulation; Purinones; Quinazolines; Rats; Rats, Sprague-Dawley; Vasodilation

1996
Contractions and relaxations accompanied by endothelial nitric oxide production induced in the porcine coronary artery by Ca2+, Ba2+ and Sr2+.
    European journal of pharmacology, 1995, Oct-16, Volume: 285, Issue:2

    Topics: Animals; Barium; Calcium; Cations, Divalent; Coronary Vessels; Cyclic GMP; Diltiazem; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Strontium; Swine; Vasodilator Agents

1995
4-aminopyridine and l-cis-diltiazem block the cGMP-activated K+ channels closed by light in the molluscan extra-ocular photoreceptors.
    Brain research, 1997, Jan-16, Volume: 745, Issue:1-2

    Topics: 4-Aminopyridine; Animals; Calcium Channel Blockers; Cyclic GMP; Diltiazem; Ganglia, Invertebrate; Light; Membrane Potentials; Mollusca; Neurons; Photoreceptor Cells, Invertebrate; Potassium Channels

1997
Supersensitive dilator response to nitroglycerin but not to atrial natriuretic peptide in spastic coronary arteries in coronary spastic angina.
    The American journal of cardiology, 1997, Mar-01, Volume: 79, Issue:5

    Topics: Adult; Aged; Angina Pectoris; Atrial Natriuretic Factor; Biological Availability; Coronary Angiography; Coronary Vasospasm; Coronary Vessels; Cyclic GMP; Diltiazem; Female; Guanylate Cyclase; Humans; Injections, Intra-Arterial; Male; Middle Aged; Nitric Oxide; Nitroglycerin; Vasodilator Agents

1997
Cyclic nucleotide-gated cation channels mediate sodium absorption by IMCD (mIMCD-K2) cells.
    The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 1

    Topics: Amiloride; Amino Acid Sequence; Animals; Biological Transport, Active; Calcium; Clone Cells; Cyclic GMP; Diltiazem; Ion Channel Gating; Ion Channels; Kidney Medulla; Kidney Tubules, Collecting; Magnesium; Membrane Potentials; Mice; Molecular Sequence Data; Nucleotides, Cyclic; Patch-Clamp Techniques; Sodium; Sodium Channels

1997
Single-channel properties of ionic channels gated by cyclic nucleotides.
    Biophysical journal, 1997, Volume: 72, Issue:3

    Topics: Amino Acid Sequence; Animals; Cattle; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Female; Humans; Ion Channel Gating; Ion Channels; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Oocytes; Point Mutation; Probability; Recombinant Proteins; Retinal Rod Photoreceptor Cells; RNA, Messenger; Sequence Homology, Amino Acid; Thermodynamics; Xenopus laevis

1997
Antagonists of the cGMP-gated conductance of vertebrate rods block the photocurrent in scallop ciliary photoreceptors.
    The Journal of physiology, 1997, Apr-15, Volume: 500 ( Pt 2)

    Topics: Amiloride; Animals; Calcium Channel Blockers; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Electric Conductivity; Ion Channel Gating; Mollusca; Patch-Clamp Techniques; Photoreceptor Cells, Invertebrate; Retinal Rod Photoreceptor Cells

1997
Role of potassium channels in relaxations of canine middle cerebral arteries induced by nitric oxide donors.
    Stroke, 1997, Volume: 28, Issue:6

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; 4-Aminopyridine; Animals; Barium Compounds; Cerebral Arteries; Charybdotoxin; Chlorides; Cyclic GMP; Diltiazem; Dogs; Glyburide; In Vitro Techniques; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Potassium Channels; Purinones; Vasodilation; Vasodilator Agents

1997
Nitric oxide induces transient Ca2+ changes in endothelial cells independent of cGMP.
    Journal of cellular physiology, 1997, Volume: 172, Issue:3

    Topics: Adenosine Triphosphate; Caffeine; Calcium; Cell Line; Cyclic GMP; Dantrolene; Diltiazem; Endothelium, Vascular; Enzyme Activation; Guanylate Cyclase; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Nitric Oxide; Nitroprusside; Penicillamine; Procaine; Ryanodine; S-Nitroso-N-Acetylpenicillamine; Thapsigargin

1997
Identification of a domain on the beta-subunit of the rod cGMP-gated cation channel that mediates inhibition by calcium-calmodulin.
    The Journal of biological chemistry, 1998, Apr-10, Volume: 273, Issue:15

    Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium; Calmodulin; Cattle; Cloning, Molecular; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Egtazic Acid; Humans; Ion Channels; Macromolecular Substances; Molecular Sequence Data; Peptide Fragments; Recombinant Proteins; Retinal Rod Photoreceptor Cells; Sequence Alignment; Sequence Homology, Amino Acid

1998
Divalent cation selectivity is a function of gating in native and recombinant cyclic nucleotide-gated ion channels from retinal photoreceptors.
    The Journal of general physiology, 1999, Volume: 113, Issue:6

    Topics: Ambystoma; Animals; Bass; Calcium; Calcium Channel Blockers; Calcium Channels; Cations, Divalent; Cattle; Cesium; Cyclic GMP; Diltiazem; Dimethylamines; Dose-Response Relationship, Drug; Electrophysiology; Ion Channel Gating; Ligands; Membrane Potentials; Methylamines; Mutagenesis; Oocytes; Quaternary Ammonium Compounds; Recombinant Proteins; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Sodium; Xenopus

1999
Nitric oxide inhibits whole-cell current in cystic fibrosis pancreatic epithelial cells.
    Pancreas, 1999, Volume: 19, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Calcium Channel Blockers; Cell Line; Charybdotoxin; Cyclic AMP; Cyclic GMP; Cystic Fibrosis; Diltiazem; Enzyme Inhibitors; Epithelial Cells; Glutathione; Humans; Membrane Potentials; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Pancreas; Patch-Clamp Techniques; Penicillamine; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione

1999
Characteristics of heterogeneity in the expression of vasoconstriction in response to N(G)-monomethyl-L-arginine in isolated canine arteries.
    European journal of pharmacology, 1999, Aug-27, Volume: 379, Issue:2-3

    Topics: Animals; Arteries; Charybdotoxin; Cyclic GMP; Diltiazem; Dogs; Enzyme Inhibitors; Nicardipine; Nitric Oxide; omega-N-Methylarginine; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents

1999
Retinitis pigmentosa: rod photoreceptor rescue by a calcium-channel blocker in the rd mouse.
    Nature medicine, 1999, Volume: 5, Issue:10

    Topics: Animals; Calcium Channel Blockers; Cyclic GMP; Diltiazem; Disease Models, Animal; Electroretinography; Ion Channel Gating; Mice; Mice, Mutant Strains; Neuroprotective Agents; Phosphoric Diester Hydrolases; Retina; Retinal Rod Photoreceptor Cells; Retinitis Pigmentosa

1999
Constraining the subunit order of rod cyclic nucleotide-gated channels reveals a diagonal arrangement of like subunits.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Jan-18, Volume: 97, Issue:2

    Topics: Animals; Cattle; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Dimerization; Drug Synergism; Electrophysiology; Female; Ion Channels; Membrane Potentials; Nickel; Oocytes; Protein Structure, Quaternary; RNA, Messenger; Xenopus

2000
Molecular cloning and functional characterization of a new modulatory cyclic nucleotide-gated channel subunit from mouse retina.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Feb-15, Volume: 20, Issue:4

    Topics: Amino Acid Sequence; Animals; Calcium; Cell Line; Cloning, Molecular; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Humans; Ion Channels; Macromolecular Substances; Membrane Potentials; Mice; Molecular Sequence Data; Rats; Recombinant Proteins; Retina; Sequence Alignment; Sequence Homology, Amino Acid; Transfection

2000
Coexpression of alpha and beta subunits of the rod cyclic GMP-gated channel restores native sensitivity to cyclic AMP: role of D604/N1201.
    Biophysical journal, 2000, Volume: 78, Issue:3

    Topics: Amino Acid Substitution; Animals; Cattle; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Ion Channel Gating; Ion Channels; Macromolecular Substances; Membrane Potentials; Models, Biological; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Probability; Retinal Rod Photoreceptor Cells

2000
Antiplatelet mechanisms of TA-993 and its metabolite MB3 in ADP-induced platelet aggregation.
    European journal of pharmacology, 2000, Jul-07, Volume: 399, Issue:2-3

    Topics: Actins; Adenosine Diphosphate; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Fibrinogen; Fura-2; Humans; Male; Oligopeptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Binding

2000
Contribution of amiloride-insensitive pathways to alveolar fluid clearance in adult rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 90, Issue:4

    Topics: Adrenergic beta-Agonists; Amiloride; Animals; Body Fluids; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Diltiazem; Hemodynamics; Ion Channels; Male; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Terbutaline; Vasodilator Agents

2001
cAMP modulates the excitability of immortalized H=hypothalamic (GT1) neurons via a cyclic nucleotide gated channel.
    Molecular endocrinology (Baltimore, Md.), 2001, Volume: 15, Issue:6

    Topics: Adrenergic alpha-Agonists; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Diltiazem; Enzyme Inhibitors; Hypothalamus; Ion Channels; Isoquinolines; Microscopy, Fluorescence; Microscopy, Video; Neurons; Patch-Clamp Techniques; Sulfonamides

2001
Electrophysiological characteristics of rat gustatory cyclic nucleotide--gated channel expressed in Xenopus oocytes.
    Journal of neurophysiology, 2001, Volume: 85, Issue:6

    Topics: Amino Acid Sequence; Animals; Calcium Channel Blockers; Cations, Monovalent; Cloning, Molecular; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; DNA, Complementary; Electric Conductivity; Female; Gene Expression; Ion Channel Gating; Ion Channels; Kinetics; Magnesium; Membrane Potentials; Microinjections; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Rats; Xenopus laevis

2001
Interactions of sildenafil with various coronary vasodilators in isolated porcine coronary artery.
    European journal of pharmacology, 2002, Feb-22, Volume: 437, Issue:3

    Topics: Animals; Celiprolol; Coronary Vessels; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Nicorandil; Nitroprusside; Pinacidil; Piperazines; Propanolamines; Purines; Sildenafil Citrate; Sulfones; Swine; Vasodilation; Vasodilator Agents

2002
Regulation of structural plasticity by different channel types in rod and cone photoreceptors.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Aug-15, Volume: 22, Issue:16

    Topics: Ambystoma; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Cobalt; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Eye Proteins; Ion Channels; Membrane Glycoproteins; Nerve Tissue Proteins; Neurites; Neuronal Plasticity; Nicardipine; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Rod Opsins; Synaptic Vesicles; Synaptophysin; Verapamil

2002
Achromatopsia-associated mutation in the human cone photoreceptor cyclic nucleotide-gated channel CNGB3 subunit alters the ligand sensitivity and pore properties of heteromeric channels.
    The Journal of biological chemistry, 2003, Sep-05, Volume: 278, Issue:36

    Topics: Amino Acid Sequence; Animals; Calcium Channel Blockers; Cell Membrane; Color Vision Defects; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Dimerization; Dose-Response Relationship, Drug; Electrophysiology; Green Fluorescent Proteins; Humans; Ion Channels; Kinetics; Ligands; Luminescent Proteins; Microscopy, Confocal; Models, Biological; Molecular Sequence Data; Mutation; Oocytes; Photoreceptor Cells; Potassium; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Retinal Cone Photoreceptor Cells; RNA, Messenger; Sequence Homology, Amino Acid; Xenopus laevis

2003
Atypical relaxation by scorpion venom in the lamb urethral smooth muscle involves both NO-dependent and -independent responses.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:3

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cyclic GMP; Diltiazem; Female; In Vitro Techniques; Ion Channel Gating; Isometric Contraction; Muscle Relaxation; Muscle, Smooth; Neuromuscular Depolarizing Agents; Nitric Oxide; omega-Conotoxin GVIA; omega-Conotoxins; Scorpion Venoms; Sheep; Sodium Channels; Tetrodotoxin; Urethra

2003
Subunit configuration of heteromeric cone cyclic nucleotide-gated channels.
    Neuron, 2004, May-13, Volume: 42, Issue:3

    Topics: Animals; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Dose-Response Relationship, Drug; Female; Humans; Ion Channels; Protein Subunits; Retinal Cone Photoreceptor Cells; Xenopus laevis

2004
Detection and localization of a putative cyclic-GMP-activated channel protein in the protozoan ciliate Stentor coeruleus.
    Protoplasma, 2006, Volume: 227, Issue:2-4

    Topics: Animals; Carrier Proteins; Cattle; Ciliophora; Cyclic AMP; Cyclic GMP; Diltiazem; Immunoblotting; Intracellular Signaling Peptides and Proteins; Ion Channels; Liposomes; Protein Transport; Protozoan Proteins; Rod Cell Outer Segment

2006
Interaction between prostaglandin E2 and l-cis-diltiazem, a specific blocker of cyclic nucleotide gated channels in bovine aortic endothelial cells.
    European journal of pharmacology, 2006, Aug-14, Volume: 543, Issue:1-3

    Topics: Animals; Aorta; Binding, Competitive; Calcium Channel Blockers; Calcium Signaling; Calcium-Transporting ATPases; Cattle; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Dinoprostone; Endothelial Cells; Enzyme Inhibitors; Ion Channel Gating; Ion Channels; Nucleotides, Cyclic; Thapsigargin

2006
Endothelium-dependent induction of vasorelaxation by the butanol extract of Phellinus igniarius in isolated rat aorta.
    The American journal of Chinese medicine, 2006, Volume: 34, Issue:4

    Topics: Animals; Aorta; Atropine; Butanols; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; In Vitro Techniques; Indomethacin; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Oxadiazoles; Polyporaceae; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Vasodilation; Vasodilator Agents; Verapamil

2006
Clinical efficacy of benidipine for vasospastic angina pectoris.
    Arzneimittel-Forschung, 2007, Volume: 57, Issue:1

    Topics: Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Coronary Vasospasm; Cyclic GMP; Dihydropyridines; Diltiazem; Female; Heart Rate; Humans; Male; Middle Aged; Nitric Oxide; Treatment Failure; Treatment Outcome; Vasodilator Agents

2007
Light-sensitive neurons and channels mediate phototaxis in C. elegans.
    Nature neuroscience, 2008, Volume: 11, Issue:8

    Topics: Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enzyme Inhibitors; Guanylate Cyclase; Ion Channels; Light; Motor Activity; Neurons, Afferent; Paralysis; Patch-Clamp Techniques; Ultraviolet Rays; Vision, Ocular

2008
CNGA2 contributes to ATP-induced noncapacitative Ca2+ influx in vascular endothelial cells.
    Journal of vascular research, 2010, Volume: 47, Issue:2

    Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aminoquinolines; Aniline Compounds; Animals; Calcium Channel Blockers; Calcium Signaling; Cattle; Cells, Cultured; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Endothelial Cells; Enzyme Inhibitors; Imines; Male; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; RNA Interference; Thionucleotides; Time Factors; Transfection; Vasodilation; Xanthenes

2010
Cyclic nucleotide-gated channels are involved in phototransduction of dermal photoreceptors in Lymnaea stagnalis.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2010, Volume: 180, Issue:8

    Topics: Animals; Boron Compounds; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Interneurons; Light Signal Transduction; Lymnaea; Photic Stimulation; Photoreceptor Cells; Skin Physiological Phenomena

2010
Expression of olfactory-type cyclic nucleotide-gated channels in rat cortical astrocytes.
    Glia, 2012, Volume: 60, Issue:9

    Topics: Animals; Astrocytes; Cerebral Cortex; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Ion Channel Gating; Patch-Clamp Techniques; Rats; Rats, Wistar

2012
Disease-associated mutations in CNGB3 promote cytotoxicity in photoreceptor-derived cells.
    Molecular vision, 2013, Volume: 19

    Topics: Animals; Annexin A5; Calcium; Cell Death; Cell Survival; Color Vision Defects; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Extracellular Space; Ion Channel Gating; Ligands; Mutation; Photoreceptor Cells, Vertebrate; Protective Agents; Xenopus

2013
Capacitation and Ca(2+) influx in spermatozoa: role of CNG channels and protein kinase G.
    Andrology, 2014, Volume: 2, Issue:1

    Topics: Animals; Calcium; Calcium Channel Blockers; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Ion Transport; Male; Mice; Patch-Clamp Techniques; Protein Kinase Inhibitors; Sperm Capacitation; Spermatozoa

2014
S-nitrosothiols dilate the mesenteric artery more potently than the femoral artery by a cGMP and L-type calcium channel-dependent mechanism.
    Nitric oxide : biology and chemistry, 2016, 08-31, Volume: 58

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cyclic GMP; Cysteine; Diltiazem; Female; Femoral Artery; Fetus; Indazoles; Male; Mesenteric Arteries; Nifedipine; Oxadiazoles; Quinoxalines; S-Nitrosoglutathione; S-Nitrosothiols; Sheep; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents

2016
Redefining the role of Ca
    Cell death & disease, 2022, 01-10, Volume: 13, Issue:1

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Death; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Ion Channel Gating; Kinetics; Mice; Proteolysis; Retinal Cone Photoreceptor Cells; Retinal Degeneration; Retinal Rod Photoreceptor Cells

2022