Page last updated: 2024-08-23

diltiazem and clonazepam

diltiazem has been researched along with clonazepam in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's2 (13.33)18.2507
2000's7 (46.67)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Carafoli, E; Chiesi, M; Eichenberger, K; Gazzotti, P; Rogg, H1
Doane, JD; Matlib, MA; Riccippo-Neto, F; Sperelakis, N1
Matlib, MA; Schwartz, A1
Conforti, L; Cox, DA; Matlib, MA; Sperelakis, N1
Cox, DA; Matlib, MA1
Cheranov, SY; Jaggar, JH1
Ahn, JR; Thu, le T; Woo, SH1
Jasani, N; Ramdas, S; Riesenberg, LA1

Reviews

1 review(s) available for diltiazem and clonazepam

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

14 other study(ies) available for diltiazem and clonazepam

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Stereospecific action of diltiazem on the mitochondrial Na-Ca exchange system and on sarcolemmal Ca-channels.
    Biochemical pharmacology, 1987, Sep-01, Volume: 36, Issue:17

    Topics: Animals; Carrier Proteins; Clonazepam; Diltiazem; Guinea Pigs; Heart; Ion Channels; Male; Mitochondria, Heart; Mitochondria, Liver; Myocardium; Sarcolemma; Sodium-Calcium Exchanger; Stereoisomerism; Structure-Activity Relationship

1987
Clonazepam and diltiazem both inhibit sodium-calcium exchange of mitochondria, but only diltiazem inhibits the slow action potentials of cardiac muscles.
    Biochemical and biophysical research communications, 1985, Apr-16, Volume: 128, Issue:1

    Topics: Action Potentials; Animals; Benzazepines; Benzodiazepinones; Calcium; Clonazepam; Diltiazem; Guinea Pigs; Isoproterenol; Mitochondria, Heart; Myocardial Contraction; Sodium

1985
Selective effects of diltiazem, a benzothiazepine calcium channel blocker, and diazepam, and other benzodiazepines on the Na+/Ca2+ exchange carrier system of heart and brain mitochondria.
    Life sciences, 1983, Jun-20, Volume: 32, Issue:25

    Topics: Animals; Benzazepines; Benzodiazepines; Benzodiazepinones; Brain; Calcium; Carrier Proteins; Clonazepam; Diazepam; Diltiazem; Flumazenil; Mitochondria; Mitochondria, Heart; Rabbits; Rats; Sodium; Sodium-Calcium Exchanger

1983
Selectivity of inhibition of Na(+)-Ca2+ exchange of heart mitochondria by benzothiazepine CGP-37157.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:4

    Topics: Animals; Calcium; Clonazepam; Diltiazem; Male; Mitochondria, Heart; Rabbits; Sodium; Sodium-Potassium-Exchanging ATPase; Thiazepines

1993
A role for the mitochondrial Na(+)-Ca2+ exchanger in the regulation of oxidative phosphorylation in isolated heart mitochondria.
    The Journal of biological chemistry, 1993, Jan-15, Volume: 268, Issue:2

    Topics: Animals; Calcium; Carrier Proteins; Cell Fractionation; Clonazepam; Diltiazem; Fura-2; Homeostasis; Male; Malonates; Mitochondria, Heart; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Rabbits; Sodium; Sodium-Calcium Exchanger; Spectrometry, Fluorescence; Thiazepines

1993
Mitochondrial modulation of Ca2+ sparks and transient KCa currents in smooth muscle cells of rat cerebral arteries.
    The Journal of physiology, 2004, May-01, Volume: 556, Issue:Pt 3

    Topics: Animals; Bongkrekic Acid; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Calcium-Binding Proteins; Calcium-Transporting ATPases; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cells, Cultured; Cerebral Arteries; Clonazepam; Cyclosporine; Diltiazem; Female; Hydrogen Peroxide; Indazoles; Ion Channels; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria, Muscle; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocytes, Smooth Muscle; Oligomycins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Rhodamines; Rotenone; Ruthenium Compounds; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Thapsigargin; Thiazepines

2004
Inhibition of L-type Ca2+ channel by mitochondrial Na+-Ca2+ exchange inhibitor CGP-37157 in rat atrial myocytes.
    European journal of pharmacology, 2006, Dec-15, Volume: 552, Issue:1-3

    Topics: Animals; Barium; Calcium Channel Blockers; Calcium Channels, L-Type; Chelating Agents; Clonazepam; Diltiazem; Dose-Response Relationship, Drug; Egtazic Acid; Heart Atria; Ion Channels; Male; Membrane Potentials; Mitochondrial Proteins; Myocytes, Cardiac; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Thiazepines

2006
Drug overdose with refractory bradycardia and hypotension.
    Delaware medical journal, 2011, Volume: 83, Issue:6

    Topics: Antihypertensive Agents; Bradycardia; Clonazepam; Diltiazem; Drug Overdose; Female; GABA Modulators; Humans; Hypotension; Metoprolol; Middle Aged

2011