Page last updated: 2024-08-23

diltiazem and carbamazepine

diltiazem has been researched along with carbamazepine in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.53)18.7374
1990's7 (18.42)18.2507
2000's12 (31.58)29.6817
2010's12 (31.58)24.3611
2020's3 (7.89)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Grossman, E; Maoz, E; Rosenthal, T; Thaler, M1
Mosley, MR; Shaughnessy, AF1
Bahls, FH; Ozuna, J; Ritchie, DE1
al-Humayyd, MS1
Ahmad, S1
Calabrese, JR; Gadde, K1
Brodie, MJ; MacPhee, GJ1
Ochodnický, M1
Carter, BL; Eimer, M1
Ngan, ET; Vincent, SR1
Arendt, C; Bazzell, MC; Wijdicks, EF1
Choi, K; Jung, J; Kim, PG; Kim, Y; Park, J; Park, S1
Benotti, MJ; Brownawell, BJ1
Ames, A; Czajkowski, KP; Fang, M; Spongberg, AL; Witter, JD; Wu, C1
Bakırdere, S; Gökçay, CF; Komesli, OT; Muz, M; Sönmez, MS1
Brooks, BW; Chambliss, CK; Conkle, JL; Haddad, SP; Matson, CW; Saari, GN; Scott, WC1
Higashi, T; Nakashima, K; Nakatake, Y; Okumura, A; Tabuchi, M; Tsuneoka, Y; Yamada, M; Yoshizawa, K1
Chang, H; Chen, C; Du, H; Guan, C; Li, C; Qiu, L; Wang, S; Wang, T; Wu, Y; Zhang, L; Zhang, S; Zhou, H1
Tan, MH; Yahya, R; Yee, SY1

Reviews

1 review(s) available for diltiazem and carbamazepine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

37 other study(ies) available for diltiazem and carbamazepine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
    Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18

    Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Carbamazepine neurotoxic reaction after administration of diltiazem.
    Archives of internal medicine, 1992, Volume: 152, Issue:12

    Topics: Carbamazepine; Diltiazem; Drug Interactions; Epilepsy; Female; Humans; Hypertension; Middle Aged; Nervous System Diseases; Substance Withdrawal Syndrome

1992
Elevated carbamazepine levels associated with diltiazem use.
    Neurology, 1992, Volume: 42, Issue:4

    Topics: Aged; Carbamazepine; Diltiazem; Humans; Hypertension; Male; Seizures

1992
Interactions between calcium channel blockers and the anticonvulsants carbamazepine and phenytoin.
    Neurology, 1991, Volume: 41, Issue:5

    Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Carbamazepine; Diltiazem; Drug Interactions; Female; Humans; Male; Middle Aged; Nifedipine; Phenytoin; Retrospective Studies; Seizures; Verapamil

1991
Elevation of carbamazepine plasma levels by diltiazem in rabbits: a potentially important drug interaction.
    Biopharmaceutics & drug disposition, 1990, Volume: 11, Issue:5

    Topics: Animals; Carbamazepine; Diltiazem; Drug Interactions; Half-Life; Male; Rabbits; Spectrophotometry, Ultraviolet

1990
Diltiazem-carbamazepine interaction.
    American heart journal, 1990, Volume: 120, Issue:6 Pt 1

    Topics: Aged; Angina Pectoris; Carbamazepine; Diltiazem; Drug Interactions; Female; Humans; Hypertension; Trigeminal Neuralgia

1990
Diltiazem effect on carbamazepine levels in manic depression.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:5

    Topics: Bipolar Disorder; Carbamazepine; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Male; Metabolic Clearance Rate; Middle Aged

1990
Carbamazepine neurotoxicity precipitated by diltiazem.
    British medical journal (Clinical research ed.), 1986, May-03, Volume: 292, Issue:6529

    Topics: Adult; Benzazepines; Carbamazepine; Diltiazem; Drug Interactions; Humans; Male; Nervous System Diseases

1986
[Clinically important interactions of carbamazepine with verapamil and diltiazem].
    Ceskoslovenska neurologie a neurochirurgie, 1988, Volume: 51, Issue:4

    Topics: Carbamazepine; Diltiazem; Drug Interactions; Humans; Verapamil

1988
Elevated serum carbamazepine concentrations following diltiazem initiation.
    Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:4

    Topics: Aged; Carbamazepine; Diltiazem; Drug Interactions; Female; Humans; Nervous System Diseases

1987
Carbamazepine and L-type calcium channel inhibitors: a binding assay study.
    Biological psychiatry, 1996, Jun-01, Volume: 39, Issue:11

    Topics: Analgesics, Non-Narcotic; Animals; Binding, Competitive; Calcium Channel Blockers; Carbamazepine; Diltiazem; In Vitro Techniques; Isradipine; Lithium; Male; Phenethylamines; Rats; Rats, Wistar; Verapamil

1996
Postoperative ophthalmoplegia and ataxia due to carbamazepine toxicity facilitated by diltiazem.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2004, Volume: 24, Issue:1

    Topics: Anastomosis, Surgical; Antimanic Agents; Aorta; Ataxia; Carbamazepine; Cardiovascular Agents; Diltiazem; Drug Interactions; Female; Humans; Iliac Artery; Middle Aged; Ophthalmoplegia; Postoperative Complications

2004
Aquatic toxicity of acetaminophen, carbamazepine, cimetidine, diltiazem and six major sulfonamides, and their potential ecological risks in Korea.
    Environment international, 2007, Volume: 33, Issue:3

    Topics: Acetaminophen; Aliivibrio fischeri; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Carbamazepine; Cimetidine; Daphnia; Diltiazem; Environmental Monitoring; Histamine H2 Antagonists; Korea; Lethal Dose 50; Oryzias; Quantitative Structure-Activity Relationship; Risk Assessment; Sulfonamides; Water Pollutants, Chemical

2007
Microbial degradation of pharmaceuticals in estuarine and coastal seawater.
    Environmental pollution (Barking, Essex : 1987), 2009, Volume: 157, Issue:3

    Topics: Absorption; Antipyrine; Bacteria; Biodegradation, Environmental; Caffeine; Carbamazepine; Cotinine; Diltiazem; Ecology; Endocrine Disruptors; Half-Life; New York; Nifedipine; Pharmaceutical Preparations; Seawater; Solubility; Sulfamethoxazole; Trimethoprim; Waste Disposal, Fluid; Water Microbiology; Water Pollutants, Chemical

2009
Dissipation and leaching potential of selected pharmaceutically active compounds in soils amended with biosolids.
    Archives of environmental contamination and toxicology, 2010, Volume: 59, Issue:3

    Topics: Carbamazepine; Clindamycin; Diltiazem; Diphenhydramine; Environmental Restoration and Remediation; Fluoxetine; Pharmaceutical Preparations; Sewage; Soil Pollutants

2010
Determination of selected natural hormones and endocrine disrupting compounds in domestic wastewater treatment plants by liquid chromatography electrospray ionization tandem mass spectrometry after solid phase extraction.
    The Analyst, 2012, Feb-21, Volume: 137, Issue:4

    Topics: Carbamazepine; Diltiazem; Endocrine Disruptors; Environmental Monitoring; Estrone; Progesterone; Sewage; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Turkey; Water Pollutants, Chemical

2012
Influence of salinity and pH on bioconcentration of ionizable pharmaceuticals by the gulf killifish, Fundulus grandis.
    Chemosphere, 2019, Volume: 229

    Topics: Animals; Carbamazepine; Diltiazem; Diphenhydramine; Estuaries; Fundulidae; Gulf of Mexico; Humans; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Pharmacokinetics; Salinity; Texas; Water Pollutants, Chemical

2019
Benzothiazepines, diltiazem and JTV-519, exert an anxiolytic-like effect via neurosteroid biosynthesis in mice.
    Journal of pharmacological sciences, 2020, Volume: 143, Issue:3

    Topics: 5-alpha Reductase Inhibitors; Animals; Anti-Anxiety Agents; Behavior, Animal; Carbamazepine; Diltiazem; Dose-Response Relationship, Drug; Finasteride; Male; Mice, Inbred C57BL; Neurosteroids; Pregnanolone; Thiazepines; Valproic Acid

2020
Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats.
    Pharmacology research & perspectives, 2021, Volume: 9, Issue:5

    Topics: Animals; Antipyrine; Atenolol; Carbamazepine; Cell Membrane; Digoxin; Diltiazem; Diphenhydramine; Drug Elimination Routes; Gabapentin; Lamotrigine; Liver; Memantine; Membrane Transport Proteins; Microdialysis; Muscle, Skeletal; Ofloxacin; Pharmaceutical Preparations; Propranolol; Pyrilamine; Quinidine; Rats; Terfenadine

2021
Lessons of the month 2: A case of inappropriate drug-drug interaction in kidney transplant.
    Clinical medicine (London, England), 2022, Volume: 22, Issue:2

    Topics: Anticonvulsants; Carbamazepine; Child; Diltiazem; Diplopia; Drug Interactions; Gait; Gait Disorders, Neurologic; Humans; Kidney Transplantation; Nystagmus, Pathologic

2022