diltiazem has been researched along with bepridil in 67 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (55.22) | 18.7374 |
| 1990's | 14 (20.90) | 18.2507 |
| 2000's | 10 (14.93) | 29.6817 |
| 2010's | 6 (8.96) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Dubinsky, B; Moore, JB; Press, JB; Sanfilippo, PJ; Urbanski, M | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M | 1 |
| Keserü, GM | 1 |
| Li, J; Rajamani, R; Reynolds, CH; Tounge, BA | 1 |
| Cianchetta, G; Cruciani, G; Fravolini, A; Giesing, D; Singleton, RW; Vaz, RJ; Wildgoose, M; Zhang, M | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Jia, L; Sun, H | 1 |
| Caron, G; Ermondi, G; Visentin, S | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Crevat, A; Gallice, P; Kovacic, H | 1 |
| DiBianco, R | 1 |
| Boucher, CA; Christensen, DM; Higgins, J; Zusman, RM | 1 |
| Haas, M; Punt, NC; van Amsterdam, FT; Zaagsma, J | 1 |
| Singh, BN | 1 |
| Fabrègues, E; John, GW; Kamal, M; Massingham, R | 1 |
| Boucher, M; Dubray, C; Duchêne-Marullaz, P | 1 |
| Coudray, P; Funck-Brentano, C; Jaillon, P; Motté, G; Planellas, J | 1 |
| Coudray, P; Coumel, P; Maison Blanche, P; Puech, P | 1 |
| Huff, JW; Reinach, PS | 1 |
| Kojima, M; Sperelakis, N | 1 |
| Barhanin, J; Borsotto, M; Fosset, M; Galizzi, JP; Lazdunski, M; Renaud, JF; Romey, G; Schmid, A | 1 |
| Balwierczak, JL; Johnson, CL; Schwartz, A | 1 |
| Ogawa, N; Ono, H; Yokota, S | 1 |
| Boddeke, HW; Heynis, JB; van Zwieten, PA; Wilffert, B | 1 |
| Lugnier, C; Schaeffer, P; Stoclet, JC | 1 |
| Lamar, JC; Leboeuf, J; Massingham, R; Ponsonnaille, J | 1 |
| Beckeringh, JJ; Hugtenburg, JG; Mathy, MJ; van Zwieten, PA | 1 |
| Allessie, MA; Bonke, FI; Kirchhof, CJ | 1 |
| Balwierczak, JL; Grupp, G; Grupp, IL; Schwartz, A | 1 |
| Brown, NL; Sirugue, O; Worcel, M | 1 |
| Fosset, M; Galizzi, JP; Lazdunski, M | 2 |
| Barhanin, J; Borsotto, M; Fosset, M; Galizzi, JP; Lazdunski, M | 1 |
| Miller, RC; Schoeffter, P | 1 |
| Zannad, F | 1 |
| Cartheuser, CF | 1 |
| Chiba, S; Kobayashi, M; Ogiwara, Y; Shimotori, M | 1 |
| Bajolet, A; Ducloux, G; Guermonprez, JL; Manouvrier, J | 1 |
| Aoki, K; Fujimoto, S; Matsuda, T | 1 |
| Lucchesi, BR; Lynch, JJ; Montgomery, DG | 1 |
| Watts, JA | 1 |
| Alatienne, M; Duchêne-Marullaz, P; Ghyselinck, N; Kantelip, JP; Talmant, JM | 1 |
| Beaughard, M; Lamar, JC; Michelin, MT; Tisne-Versailles, J | 1 |
| Harwell, T; Maiorano, P; Watts, J | 1 |
| Dang Tran, L; Gaillard, G; Montastruc, JL; Montastruc, P; Valet, P | 1 |
| Escoubet, B; Griffaton, G; Lechat, P; Samuel, JL | 1 |
| Balwierczak, J; Lathrop, DA; Matlib, MA; Schwartz, A | 1 |
| Martre, H; Singlas, E; Taburet, AM | 1 |
| Pang, DC; Sperelakis, N | 2 |
| Mras, S; Sperelakis, N | 1 |
| Advenier, C; Cerrina, J; Duroux, P; Floch, A; Renier, A | 1 |
| Allain, P; Leblondel, G | 1 |
| Chauvet-Monges, AM; Crevat, A; Salducci, MD; Tabouy, L | 1 |
| Ito, K; Ito, KM; Murakami, K; Shindo, K | 1 |
| Bory, M; Quilliet, L | 1 |
| Quilliet, L; Sellier, P | 1 |
| Cascio, WE; Chowdhury, MK; Crouse, JR; Jollis, JG; Massing, MW; Simpson, RJ; Smith, SC | 1 |
| Brown, AM; Ransom, BR; Wender, R | 1 |
| Hong, JM; Kim, J; Lee, SH; Ok, SH; Park, J; Shin, IW; Sohn, JT; Woo, MS | 1 |
2 review(s) available for diltiazem and bepridil
| Article | Year |
|---|---|
Bepridil treatment of chronic stable angina: a review of comparative studies versus placebo, nifedipine, and diltiazem.
Topics: Adult; Aged; Angina Pectoris; Bepridil; Chronic Disease; Diltiazem; Female; Humans; Male; Meta-Analysis as Topic; Middle Aged; Nifedipine | 1992 |
[Clinical pharmacology of calcium inhibitors].
Topics: Age Factors; Animals; Bepridil; Biological Availability; Biotransformation; Calcium Channel Blockers; Diltiazem; Dogs; Half-Life; Humans; Intestinal Absorption; Kidney Failure, Chronic; Kinetics; Liver Diseases; Metabolic Clearance Rate; Nifedipine; Perhexiline; Protein Binding; Pyrrolidines; Rats; Tissue Distribution; Verapamil | 1985 |
6 trial(s) available for diltiazem and bepridil
| Article | Year |
|---|---|
Comparative efficacy and safety of bepridil and diltiazem in chronic stable angina pectoris refractory to diltiazem. The Bepridil Collaborative Study Group.
Topics: Adult; Aged; Angina Pectoris; Bepridil; Chronic Disease; Diltiazem; Double-Blind Method; Drug Tolerance; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged | 1991 |
Effects of bepridil and diltiazem on ventricular repolarization in angina pectoris.
Topics: Angina Pectoris; Bepridil; Diltiazem; Electrocardiography; Electrophysiology; Female; Humans; Male; Middle Aged; Prospective Studies; Ventricular Function | 1990 |
[Comparative study of the mid-term electrocardiographic and clinical tolerability of bepridil versus diltiazem in patients with coronary disease].
Topics: Aged; Bepridil; Coronary Disease; Diltiazem; Double-Blind Method; Electrocardiography; Electrocardiography, Ambulatory; Humans; Time Factors | 1990 |
[Comparison of the effects of bepridil and diltiazem in Prinzmetal's angina. Crossed, randomized, double-blind study. Apropos of 14 cases].
Topics: Adult; Angina Pectoris, Variant; Benzazepines; Bepridil; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Middle Aged; Pyrrolidines; Random Allocation | 1986 |
[Comparative study of the efficacy and tolerability of bepridil and diltiazem in unstable angina. 277 patients].
Topics: Aged; Angina, Unstable; Bepridil; Blood Pressure; Coronary Angiography; Diltiazem; Drug Evaluation; Electrocardiography; Female; Heart Rate; Humans; Male; Middle Aged | 1994 |
[Comparison of anti-ischemic effect of bepridil and diltiazem evaluated by exercise test in patients with coronary disease. A multicenter study. Groupe d'Investigateurs].
Topics: Bepridil; Calcium Channel Blockers; Coronary Disease; Diltiazem; Double-Blind Method; Exercise Test; Female; Humans; Male; Middle Aged; Vasodilator Agents | 1997 |
59 other study(ies) available for diltiazem and bepridil
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Synthesis of (aryloxy)alkylamines. 2. Novel imidazo-fused heterocycles with calcium channel blocking and local anesthetic activity.
Topics: Amines; Anesthetics, Local; Animals; Calcium Channel Blockers; Drug Evaluation, Preclinical; Heterocyclic Compounds; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Rabbits; Trachea | 1988 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2002 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A two-state homology model of the hERG K+ channel: application to ligand binding.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation | 2005 |
A pharmacophore hypothesis for P-glycoprotein substrate recognition using GRIND-based 3D-QSAR.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Fluoresceins; Fluorescent Dyes; Humans; Models, Molecular; Multivariate Analysis; Permeability; Quantitative Structure-Activity Relationship | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship | 2009 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection | 2011 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
Inhibition of sodium pump by bepridil. An in vitro and microcalorimetric study.
Topics: Adenosine Triphosphate; Bepridil; Diltiazem; Erythrocytes; Humans; Kinetics; Nicardipine; Nifedipine; Ouabain; Potassium; Sodium-Potassium-Exchanging ATPase; Verapamil | 1992 |
Effects of antianginal therapy on left ventricular systolic and diastolic performance: comparison of the response to bepridil, propranolol, and diltiazem.
Topics: Angina Pectoris; Bepridil; Diastole; Diltiazem; Exercise Test; Humans; Propranolol; Systole; Vascular Resistance; Ventricular Function, Left | 1992 |
Stereoisomers of calcium antagonists distinguish a myocardial and vascular mode of protection against cardiac ischemic injury.
Topics: Animals; Bepridil; Calcium Channel Blockers; Cardiomyopathies; Coronary Circulation; Coronary Disease; Diltiazem; Gallopamil; Hemodynamics; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Rats; Rats, Inbred Strains; Stereoisomerism | 1990 |
Caffeine-induced contractions in rabbit isolated renal artery are differentially inhibited by calcium antagonists.
Topics: Animals; Bepridil; Caffeine; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Fendiline; Flunarizine; Kinetics; Lidoflazine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rabbits; Renal Artery; Verapamil | 1991 |
Effects of bepridil, diltiazem and verapamil on atrial refractoriness and heart rate in the conscious dog: comparison with quinidine.
Topics: Animals; Arrhythmias, Cardiac; Atrial Function, Right; Bepridil; Blood Pressure; Diltiazem; Dogs; Female; Heart; Heart Rate; Male; Pressoreceptors; Quinidine; Tachycardia; Verapamil | 1991 |
Mechanism of inhibition of net ion transport across frog corneal epithelium by calcium channel antagonists.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bepridil; Calcimycin; Calcium Channel Blockers; Cornea; Cyclic AMP; Diltiazem; Electric Conductivity; Epithelium; In Vitro Techniques; Ion Channels; Isoproterenol; Kinetics; Pyrrolidines; Rana catesbeiana; Sodium-Potassium-Exchanging ATPase; Verapamil | 1985 |
Effects of calcium channel blockers on ouabain-induced oscillatory afterpotentials in organ-cultured young embryonic chick hearts.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Bepridil; Calcium Channel Blockers; Chick Embryo; Diltiazem; Ion Channels; Nifedipine; Organ Culture Techniques; Ouabain; Pyrrolidines; Verapamil | 1986 |
Dihydropyridine-sensitive Ca2+ channels: molecular properties of interaction with Ca2+ channel blockers, purification, subunit structure, and differentiation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Bepridil; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Chick Embryo; Cholic Acids; Diltiazem; Ion Channels; Isradipine; Kinetics; Macromolecular Substances; Molecular Weight; Muscles; Myocardial Contraction; Oxadiazoles; Pyridines; Pyrrolidines; Receptors, Nicotinic; Verapamil | 1986 |
The relationship between the binding site of [3H]-d-cis-diltiazem and that of other non-dihydropyridine calcium entry blockers in cardiac sarcolemma.
Topics: Allosteric Regulation; Animals; Bepridil; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Diltiazem; Dogs; In Vitro Techniques; Ion Channels; Kinetics; Pyrrolidines; Sarcolemma; Verapamil | 1987 |
Different interaction of bepridil and diltiazem with BAY K 8644 in the abolition of autoregulation of renal blood flow.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bepridil; Calcium Channel Blockers; Diltiazem; Dogs; Female; Homeostasis; Infusions, Intra-Arterial; Male; Pyrrolidines; Renal Circulation; Vascular Resistance | 1988 |
Investigation of the mechanism of negative inotropic activity of some calcium antagonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Arrhythmia Agents; Bepridil; Calcimycin; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Female; Flunarizine; Guinea Pigs; In Vitro Techniques; Lidoflazine; Male; Myocardial Contraction; Pyrrolidines; Verapamil | 1988 |
Interaction of calmodulin and calcium antagonists with [3H]diltiazem and [3H]nitrendipine binding sites.
Topics: Animals; Bepridil; Calcium Channel Blockers; Calcium Channels; Calmodulin; Diltiazem; Imidazoles; Phosphodiesterase Inhibitors; Pyrrolidines; Rats; Receptors, Nicotinic; Sulfonamides; Trifluoperazine | 1988 |
Electrophysiological effects of bepridil and its quaternary derivative CERM 11888 in closed chest anaesthetized dogs: a comparison with verapamil and diltiazem.
Topics: Anesthesia; Animals; Bepridil; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dogs; Electrocardiography; Electrophysiology; Female; Heart; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Sinoatrial Node; Time Factors; Verapamil | 1989 |
The differential effect of calcium antagonists on the positive inotropic effects induced by calcium and monensin in cardiac preparations of rats and guinea-pigs.
Topics: Animals; Bepridil; Calcium; Calcium Channel Blockers; Diltiazem; Gallic Acid; Heart Ventricles; Lidoflazine; Male; Monensin; Myocardial Contraction; Nifedipine; Papillary Muscles; Rats; Rats, Inbred Strains; Ryanodine; Stimulation, Chemical; Verapamil | 1989 |
Effects of verapamil, diltiazem and disopyramide on sinus function: a comparison with bepridil.
Topics: Animals; Bepridil; Diltiazem; Disopyramide; Dose-Response Relationship, Drug; Female; Heart Conduction System; Heart Rate; In Vitro Techniques; Male; Pyrrolidines; Rabbits; Sinoatrial Node; Verapamil | 1989 |
Effects of bepridil and diltiazem on [3H]nitrendipine binding to canine cardiac sarcolemma. Potentiation of pharmacological effects of nitrendipine by bepridil.
Topics: Animals; Benzazepines; Bepridil; Binding Sites; Binding, Competitive; Diltiazem; Dogs; Drug Synergism; In Vitro Techniques; Kinetics; Myocardial Contraction; Nifedipine; Nitrendipine; Pyrrolidines; Rats; Sarcolemma; Temperature | 1986 |
The effects of some slow channel blocking drugs on high affinity serotonin uptake by rat brain synaptosomes.
Topics: Animals; Bepridil; Brain; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Pyrrolidines; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes; Temperature; Time Factors; Verapamil | 1986 |
Characterization of the Ca2+ coordination site regulating binding of Ca2+ channel inhibitors d-cis-diltiazem, (+/-)bepridil and (-)desmethoxyverapamil to their receptor site in skeletal muscle transverse tubule membranes.
Topics: Barium; Benzazepines; Bepridil; Calcium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Gallopamil; Kinetics; Magnesium; Membranes; Microtubules; Muscles; Pyrrolidines; Receptors, Nicotinic; Strontium; Verapamil | 1985 |
Characterization and photoaffinity labeling of receptor sites for the Ca2+ channel inhibitors d-cis-diltiazem, (+/-)-bepridil, desmethoxyverapamil, and (+)-PN 200-110 in skeletal muscle transverse tubule membranes.
Topics: Affinity Labels; Animals; Autoradiography; Benzazepines; Bepridil; Binding, Competitive; Calcium Channels; Diltiazem; Isradipine; Kinetics; Muscles; Oxadiazoles; Photochemistry; Pyrrolidines; Rabbits; Receptors, Nicotinic; Verapamil | 1986 |
Role of sodium-calcium exchange and effects of calcium entry blockers on endothelial-mediated responses in rat isolated aorta.
Topics: Amiloride; Animals; Aorta; Bepridil; Calcium; Calcium Channel Blockers; Choline; Cyclic GMP; Diltiazem; Endothelium; Female; Lithium; Muscle, Smooth, Vascular; Nicergoline; Nifedipine; Pyrrolidines; Rats; Rats, Inbred Strains; Reserpine; Sodium; Verapamil | 1986 |
[Pharmacology of calcium antagonists].
Topics: Bepridil; Calcium Channel Blockers; Cardiovascular System; Diltiazem; Nifedipine; Pyrrolidines; Verapamil | 1988 |
Slow channel inhibitor effects on brain function: tolerance to severe hypoxia in the rat.
Topics: Animals; Bencyclane; Bepridil; Brain; Calcium Channel Blockers; Cinnarizine; Diltiazem; Electroencephalography; Fendiline; Flunarizine; Gallopamil; Heart Rate; Hypoxia; Nimodipine; Prenylamine; Pyrrolidines; Rats; Rats, Inbred Strains; Respiration; Verapamil | 1988 |
Effects of calcium channel blockers on sinoatrial conduction in the isolated and blood-perfused dog atrium.
Topics: Animals; Bepridil; Calcium Channel Blockers; Dilazep; Diltiazem; Dogs; Heart Rate; In Vitro Techniques; Isoindoles; Myocardial Contraction; Phthalimides; Pyrrolidines; Sinoatrial Node; Verapamil | 1986 |
Comparative effects of bepridil and diltiazem on systemic blood pressure and isolated peripheral arteries in spontaneously hypertensive rats.
Topics: Animals; Arteries; Benzazepines; Bepridil; Blood Pressure; Calcium Channel Blockers; Diltiazem; Heart Rate; Hypertension; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Pyrrolidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1986 |
The effects of calcium entry blockade on the vulnerability of infarcted canine myocardium toward ventricular fibrillation.
Topics: Animals; Benzothiazoles; Bepridil; Calcium Channel Blockers; Diltiazem; Dogs; Electrocardiography; Electrophysiology; Heart; Heart Rate; Male; Myocardial Infarction; Pyrrolidines; Thiazoles; Ventricular Fibrillation | 1986 |
Protection of ischemic hearts by Ca2+ antagonists.
Topics: Animals; Bepridil; Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Energy Metabolism; Lactates; Lactic Acid; Mitochondria, Heart; Myocardial Contraction; Nifedipine; Pyrrolidines; Rats; Rats, Inbred Strains; Verapamil | 1986 |
Comparative electrophysiologic effects of bepridil, verapamil and diltiazem in conscious and anesthetized dogs.
Topics: Anesthesia, General; Animals; Atrioventricular Node; Bepridil; Calcium Channel Blockers; Diltiazem; Dogs; Female; Heart Conduction System; Hemodynamics; Male; Pentobarbital; Pyrrolidines; Sinoatrial Node; Verapamil | 1986 |
Comparative effects of bepridil, diltiazem, nifedipine and verapamil on haemodynamic parameters and myocardial oxygen consumption in anaesthetized dogs.
Topics: Animals; Bepridil; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dogs; Female; Heart; Hemodynamics; Male; Myocardium; Nifedipine; Oxygen Consumption; Pyrrolidines; Vascular Resistance; Verapamil | 1986 |
Comparison of the effects of bepridil and diltiazem upon globally ischemic rat hearts.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bepridil; Calcium; Coronary Disease; Diltiazem; Heart; Hemodynamics; In Vitro Techniques; Mitochondria, Heart; Myocardium; Oxygen Consumption; Perfusion; Pyrrolidines; Rats; Rats, Inbred Strains | 1987 |
Effects of calcium entry blockers on blood pressure and heart rate in neurogenic hypertensive dogs.
Topics: Animals; Bepridil; Blood Pressure; Calcium Channel Blockers; Denervation; Diltiazem; Dogs; Female; Heart Rate; Hypertension; Male; Nicardipine; Nifedipine; Pyrrolidines; Sinoatrial Node; Verapamil | 1987 |
Calcium antagonists stimulate prostaglandin synthesis by cultured rat cardiac myocytes and prevent the effects of hypoxia.
Topics: Animals; Bepridil; Calcium Channel Blockers; Cells, Cultured; Cobalt; Diltiazem; Dinoprostone; Epoprostenol; Fibroblasts; Glycogen; Heart; Hypoxia; Myocardium; Prostaglandins E; Pyrrolidines; Rats; Rats, Inbred Strains; Verapamil | 1986 |
Pharmacology of calcium antagonists.
Topics: Action Potentials; Animals; Atrioventricular Node; Bepridil; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Guinea Pigs; Heart; Heart Rate; Humans; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Pyrrolidines; Rats; Vasodilation; Ventricular Fibrillation; Verapamil | 1985 |
Properties of receptors for the Ca2+-channel blocker verapamil in transverse-tubule membranes of skeletal muscle. Stereospecificity, effect of Ca2+ and other inorganic cations, evidence for two categories of sites and effect of nucleoside triphosphates.
Topics: Animals; Bepridil; Binding, Competitive; Calcium; Calcium Channels; Cations, Divalent; Cations, Monovalent; Diltiazem; Electrochemistry; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; In Vitro Techniques; Muscles; Nifedipine; Nitrendipine; Nucleotides; Pyrrolidines; Rabbits; Receptors, Nicotinic; Stereoisomerism; Verapamil | 1984 |
Nifedipine, diltiazem, bepridil and verapamil uptakes into cardiac and smooth muscles.
Topics: Animals; Benzazepines; Bepridil; Calcium Channel Blockers; Cats; Chick Embryo; Diltiazem; Ileum; In Vitro Techniques; Muscle, Smooth; Myocardium; Nifedipine; Papillary Muscles; Pyridines; Pyrrolidines; Rabbits; Time Factors; Verapamil | 1983 |
Depression of contractions of rabbit aorta and guinea pig vena cava by mesudipine and other slow channel blockers.
Topics: Animals; Aorta, Thoracic; Bepridil; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Guinea Pigs; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Potassium; Pyridines; Pyrrolidines; Rabbits; Vena Cava, Inferior; Verapamil | 1983 |
Effects of five different organic calcium antagonists on guinea-pig isolated trachea.
Topics: Animals; Anti-Arrhythmia Agents; Bepridil; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicardipine; Nifedipine; Pyrrolidines; Trachea; Verapamil | 1984 |
Ca2+ uptake and energy supply of sheep heart mitochondria in presence of some calcium antagonists.
Topics: Animals; Bepridil; Calcium; Calcium Channel Blockers; Diltiazem; Energy Metabolism; Mitochondria, Heart; Nifedipine; Prazosin; Pyrrolidines; Sheep | 1984 |
Differential actions of calcium antagonists on calcium binding to cardiac sarcolemma.
Topics: Animals; Bepridil; Binding Sites; Calcium; Calcium Channel Blockers; Diltiazem; Guinea Pigs; In Vitro Techniques; Myocardium; Nifedipine; Pyrrolidines; Sarcolemma; Verapamil | 1982 |
Protective effect of some calcium antagonists against mitochondrial calcium injury.
Topics: Adenosine Triphosphate; Amlodipine; Animals; Antihypertensive Agents; Bepridil; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Male; Mitochondria, Liver; Myocardial Ischemia; Nicardipine; Rats; Rats, Wistar; Verapamil | 1994 |
Effects of semotiadil fumarate (SD-3211) and its enantiomer, SD-3212, on the changes in cytosolic Ca2+ and tension caused by KCl and norepinephrine in isolated rat aortas.
Topics: Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; Bepridil; Calcium; Calcium Channel Blockers; Cytosol; Diltiazem; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Rats; Rats, Wistar; Stereoisomerism; Thiazoles | 1995 |
Calcium channel blockers and mortality in elderly patients with myocardial infarction.
Topics: Aged; Aged, 80 and over; Amlodipine; Bepridil; Calcium Channel Blockers; Diltiazem; Female; Humans; Logistic Models; Male; Myocardial Infarction; Nifedipine; Retrospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome; United States; Verapamil | 1999 |
Ionic mechanisms of aglycemic axon injury in mammalian central white matter.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Axons; Bepridil; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Electrophysiology; Excitatory Amino Acid Antagonists; Extracellular Space; Glucose; Kynurenic Acid; Mammals; Nifedipine; Optic Nerve; Optic Nerve Diseases; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Sodium; Sodium-Calcium Exchanger | 2001 |
Lipid emulsion alleviates the vasodilation and mean blood pressure decrease induced by a toxic dose of verapamil in isolated rat aortae and an in vivo rat model.
Topics: Animals; Aorta, Thoracic; Bepridil; Blood Pressure; Calcium Channel Blockers; Diltiazem; Emulsions; In Vitro Techniques; Male; Nifedipine; Phenylephrine; Phospholipids; Rats; Rats, Sprague-Dawley; Soybean Oil; Vasodilation; Vasodilator Agents; Verapamil | 2018 |