Page last updated: 2024-08-23

diltiazem and atorvastatin

diltiazem has been researched along with atorvastatin in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (36.84)29.6817
2010's10 (52.63)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Dalvie, D; Loi, CM; Smith, DA1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ichihara, K; Kaneta, S; Marumo, H; Satoh, K; Yamamoto, A1
Lewin, JJ; Nappi, JM; Taylor, MH1
Ashby, DT; Conditt, G; Dangas, G; Hirose, M1
Molden, E; Westergren, T1
Chang, KS; Choi, DH; Choi, JS; Hong, SP1
Eckel, RH1
Abeysinghe, N; Aston, J; Polouse, S1
Han, SH; Jang, Y; Koh, KK; Oh, PC; Park, YM1
Carroll, C; Hassanin, A1
Ainsworth, M; Bookstaver, D; Gleaton, M; Milner, E1
Bando, Y; Ishii, H; Otori, K; Yokota, N1

Reviews

2 review(s) available for diltiazem and atorvastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Interaction risk with statin switch].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2007, Feb-15, Volume: 127, Issue:4

    Topics: Anticholesteremic Agents; Anticoagulants; Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Atorvastatin; Diltiazem; Drug Interactions; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Hemorrhages; Muscular Diseases; Pyrroles; Risk Factors; Simvastatin; Warfarin

2007

Other Studies

17 other study(ies) available for diltiazem and atorvastatin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Simvastatin and atorvastatin enhance hypotensive effect of diltiazem in rats.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2001, Volume: 121, Issue:10

    Topics: Animals; Antihypertensive Agents; Atorvastatin; Blood Pressure; Diltiazem; Drug Synergism; Drug Therapy, Combination; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Pravastatin; Pyrroles; Rats; Rats, Sprague-Dawley

2001
Rhabdomyolysis with concurrent atorvastatin and diltiazem.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:10

    Topics: Acute Disease; Acute Kidney Injury; Atorvastatin; Cardiovascular Agents; Chemical and Drug Induced Liver Injury; Diltiazem; Drug Interactions; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pyrroles; Rhabdomyolysis

2002
Coronary artery spasm associated with a moderately severe atherosclerotic stenosis in the proximal LAD.
    The Journal of invasive cardiology, 2002, Volume: 14, Issue:12

    Topics: Adult; Aspirin; Atorvastatin; Cardiac Catheterization; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Coronary Vasospasm; Diltiazem; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Heptanoic Acids; Humans; Isosorbide; Pyrroles; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Ultrasonography, Interventional

2002
Effect of atorvastatin on the pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, in rats.
    Archives of pharmacal research, 2007, Volume: 30, Issue:1

    Topics: Administration, Oral; Animals; Area Under Curve; Atorvastatin; Biological Availability; Biotransformation; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Half-Life; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Intravenous; Male; Metabolic Clearance Rate; Pyrroles; Rats; Rats, Sprague-Dawley

2007
Approach to the patient who is intolerant of statin therapy.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:5

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Atorvastatin; Coronary Disease; Diltiazem; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Middle Aged; Pyrroles; Simvastatin

2010
Diltiazem overdose: a role for high-dose insulin.
    Emergency medicine journal : EMJ, 2010, Volume: 27, Issue:10

    Topics: Anticholesteremic Agents; Atorvastatin; Calcium Channel Blockers; Diltiazem; Fluid Therapy; Heptanoic Acids; Humans; Hypoglycemic Agents; Hypotension; Infusions, Intravenous; Insulin; Male; Prescription Drug Misuse; Pyrroles

2010
Diffuse three-vessel coronary artery spasm.
    International journal of cardiology, 2015, Jan-20, Volume: 179

    Topics: Atorvastatin; Coronary Vasospasm; Diagnosis, Differential; Diagnostic Imaging; Diltiazem; Drug Therapy, Combination; Electrocardiography; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isosorbide Dinitrate; Male; Middle Aged; Nitroglycerin; Pyrroles; Risk Factors; Vasodilator Agents

2015
Polypharmacy in the Elderly-When Good Drugs Lead to Bad Outcomes: A Teachable Moment.
    JAMA internal medicine, 2017, 06-01, Volume: 177, Issue:6

    Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Antihypertensive Agents; Atorvastatin; Atrial Fibrillation; Bone Density Conservation Agents; Deprescriptions; Digoxin; Diltiazem; Diuretics; Drug Overdose; Factor Xa Inhibitors; Female; Furosemide; Heart Failure; Histamine H1 Antagonists, Non-Sedating; Histamine H2 Antagonists; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ibandronic Acid; Lisinopril; Loratadine; Metoprolol; Polypharmacy; Pyrazoles; Pyridones; Ranitidine; Syncope

2017
Assessment of Anti-Xa activity in patients receiving concomitant apixaban with strong p-glycoprotein inhibitors and statins.
    Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:5

    Topics: Adult; Aged; Amiodarone; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diltiazem; Drug Interactions; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pyrazoles; Pyridones; Rosuvastatin Calcium; Simvastatin

2022
[Significant Prolongation of the International Normalized Ratio Associated with COVID-19 Treatment: Possible Drug Interaction with Remdesivir].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2022, Volume: 142, Issue:10

    Topics: Adenosine Monophosphate; Alanine; Amiodarone; Anticoagulants; Atorvastatin; Bisoprolol; COVID-19 Drug Treatment; Dexamethasone; Diltiazem; Drug Interactions; Humans; International Normalized Ratio; Male; Middle Aged; Warfarin

2022