Page last updated: 2024-08-23

diltiazem and amlodipine

diltiazem has been researched along with amlodipine in 120 studies

Research

Studies (120)

TimeframeStudies, this research(%)All Research%
pre-19904 (3.33)18.7374
1990's52 (43.33)18.2507
2000's43 (35.83)29.6817
2010's18 (15.00)24.3611
2020's3 (2.50)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ali, N; Palit, P1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Mason, RP; Moisey, DM; Shajenko, L1
Simpson, RU; Taylor, JM1
Gambini, F; Gaviraghi, G; Micheli, D; Quartaroli, M; Tarter, G; Trist, DG1
Clozel, JP; Hess, P; Véniant, M; Wolfgang, R1
Cheng, TO1
Bruzzone, F; Canale, C; Caponnetto, S; Masperone, MA; Terrachini, V1
Goldhammer, E; Sharma, SK; Silke, B; Taylor, SH; Verma, SP1
Burges, RA; Carter, AJ; Gardiner, DG1
Bevan, J; Glusa, E; Heptinstall, S1
Jackson, N; Sharma, SK; Silke, B; Taylor, SH; Verma, SP1
Frais, MA; Jackson, N; Midtbo, KA; Reynolds, G; Sharma, S; Silke, B; Taylor, SH; Verma, SP1
Betteridge, L; Chan, P; Gallagher, K; Munro, E; Patel, M; Schachter, M; Sever, P; Wolfe, J1
Chauvet-Monges, AM; Crevat, A; Salducci, MD; Tabouy, L1
Bretnall, AE; Clarke, GS1
Biscione, F; Lanza, GA; Manzoli, A; Natale, A; Santarelli, P1
Locher, R; Lupo, E; Vetter, W; Weisser, B1
Baker, BA; Cacchione, JG1
Cunningham, D; Fox, KM; Mulcahy, D; Purcell, H; Sparrow, J; Wright, C1
Taylor, SH1
Lund-Johansen, P; Omvik, P1
Decrinis, M; Kasper, K; Miyawaki, N; Stark, G; Stark, U; Tritthart, HA1
Block, LH; Eickelberg, O; Erne, P; Kohler, E; Roth, M1
Fourney, A; Leenen, FH1
Bernaud, C; Marchand, X; Morand, P; Tibi, T1
Fourney, A; Leenen, FH; Notman, G; Tanner, J1
Curry, P; Dens, J; Hagel, H; Melcher, A1
Kobrin, I; Lacourcière, Y; Massie, BM; Viskoper, R; Woittiez, A1
Davies, GJ; Kobrin, I; Tzivoni, D1
Boileau, G; Bolli, P; Handa, SP; Larochelle, P; Leenen, FH; Myers, M; Tanner, J; Wilson, TW1
White, CM1
Clegg, L; Horwitz, LD; Weinberger, HD1
Matsumori, A1
Atkinson, JB1
Hintze, TH; Zhang, X1
Haraguchi, K; Iga, T; Ito, K; Kotaki, H; Sawada, Y1
Watts, RW; Wing, LM1
Bieska, G; Charlon, V; Kobrin, I; Lindberg, E; Pordy, R1
Fox, KM; Knight, CJ1
Massie, BM1
van Kesteren, HA; Withagen, AJ1
Deanfield, JE1
Seibold, JR; Sturgill, MG1
Doğrul, A; Yeşilyurt, O1
Butler, TJ; Ellis, JS; Robertson, P; Seymour, RA; Steele, JG; Thomason, JM1
Mason, PE; Mason, RP; Olmstead, EG; Trumbore, MW; Walter, MF1
Chierchia, SL; Fragasso, G; Margonato, A; Rossetti, E; Xuereb, M; Xuereb, RG1
Cleophas, TJ; Daniëls, MC; Hendriks, MG; Holwerda, NJ; Schelling, A; Van Der Vring, JA; Withagen, PJ2
Chen, H; Daloze, P; Dumont, L; Lapointe, N; Qi, S; Xu, D1
Cleophas, TJ; Daniëls, MC; Hendriks, MG; Holwerda, KJ; Schelling, A; van der Sluijs, J; van der Vring, JA; Withagen, AJ; Zwinderman, AH1
Mak, IT; Mason, PE; Mason, RP; Trumbore, MW1
Laufen, H; Riedel, KD; Scharpf, F; Schumacher, T; Yeates, R; Zimmermann, T1
Becker, BF; Möbert, J1
Cascio, WE; Chowdhury, MK; Crouse, JR; Jollis, JG; Massing, MW; Simpson, RJ; Smith, SC1
Göthert, M; Likungu, J; Molderings, GJ1
Bond, BR; Crawford, FA; Crumbley, AJ; Dorman, BH; Kratz, JM; Multani, MM; Spinale, FG; Zellner, JL1
Avdonin, PV; Buhler, FR; Tkachuk, VA1
Cusson, J; Lamarre-Cliche, M; Lambert, R; Larochelle, P; Van Nguyen, P; Wistaff, R1
Marche, P; Stepien, O1
Beckey, NP; Korman, L; Parra, D1
Ikeda, M; Ikeda, U; Minota, S; Ohki, R; Shimada, K; Shimpo, M; Takahashi, M; Yamamoto, K1
Matsumori, A; Nunokawa, Y; Sasayama, S1
Ahn, YK; Bae, Y; Cho, JG; Cho, JH; Jeong, MH; Kang, JC; Kang, KT; Kim, KH; Kim, NH; Kim, SH; Lee, SH; Park, JC; Rhew, JY1
Hintze, TH; Kaley, G; Loke, KE; Messina, EJ; Shesely, EG1
Acuña-Castroviejo, D; Escames, G; García, J; Khaldy, H; León, J; Macías, M; Martín, M; Vives, F1
Fujimura, A; Maeda, A; Sasaki, M1
Chugh, SK; Digpal, K; Hutchinson, T; Lahiri, A; McDonald, CJ; Miller, AJ1
Feely, J; Hennessy, M; Mahmud, A1
Alimova, EV; Kutishenko, NP; Martsevich, SIu; Sementsov, DP1
Horton, JW; Maass, DL; Sanders, B; White, DJ1
Esmore, DS; Rosenfeldt, FL1
Beckerman, B; Brennan, C; Bultas, J; Deanfield, JE; Detry, JM; Lichtlen, PR; Sellier, P; Thaulow, E; Young, ST1
Kritz, H; Oguogho, A; Sinzinger, H; Wolfram, RM1
Pope, J1
Chaitman, BR; Chumakova, G; Kuch, J; Parker, JO; Pepine, CJ; Skettino, SL; Skopal, J; Wang, W; Wolff, AA1
Lee, JD; Mitsuke, Y; Nakano, A; Shimizu, H; Ueda, T; Uzui, H; Yue, H1
Brown, CA; Brown, SA; Cartier, LM; Dietrich, UM; Mathur, S; Munday, JS; Newell, MA; Sheldon, SE1
Albert, KS; Bohannon, K; Gana, TJ; Pascual, LG; Sica, DA; Wright, JT1
Gratsianskiĭ, NA1
Stone, PH1
Aberg, JA; Fichtenbaum, CJ; Gerber, JG; Glesby, MJ; Grosskopf, N; Hafner, R; Hall, S; Kendall, MA; Zolopa, AR1
Barth, J; Bernink, PJ; de Weerd, P; Enthoven, R; Haagen, FD; Holwerda, NJ; Klomps, HC; Remme, WJ; ten, CF1
Canale, C; Caponnetto, S; Masperone, MA; Terrachini, V1
Izumi, T; Kitano, Y; Niwano, S; Sasaki, T1
Bouchard, NC; Hoffman, RS; Kanagarajan, K; Krishnan, P; Marraffa, JM; Stork, CM1
Fujiwara, H; Hattori, A; Hiei, K; Io, K; Kato, T; Kawasaki, M; Matsuo, H; Minatoguchi, S; Morita, N; Nishigaki, K; Noda, T; Ojio, S; Ono, H; Sato, H; Segawa, T; Takemura, G; Tanaka, T; Ueno, K; Watanabe, S1
Fukumoto, Y; Ito, A; Shimokawa, H; Yasuda, S1
Borowicz, KK; Czuczwar, SJ; Kimber-Trojnar, Z; Luszczki, JJ; Szostakiewicz, B; Trojnar, MK; Trojnar, MP; Zadrozniak, A1
Matsumori, A; Nishio, R; Nose, Y1
Fukumoto, Y; Inoue, Y; Minatoguchi, S; Nishigaki, K; Shimokawa, H; Sueda, S; Urata, H; Yamanouchi, Y; Yasuda, S1
Barsys, V; Duburs, G; Garaliene, V; Jakuska, P; Krauze, A1
Barsys, V; Benetis, R; Garaliene, V; Jakuška, P1
Barsys, V; Benetis, R; Garaliene, V; Giedraitis, S; Krauze, A1
Dhana, N; Jongjarearnprasert, K; Khankham, S; Kulthanan, K; Tuchinda, P1
Barceló, D; Esplugas, S; Gonzalez, O; Pérez, S; Qiang, Z; Sans, C; Xu, K; Zhu, B; Zonja, B1
Brandolini, F; Groppi, A; Moretti, M; Morini, L; Osculati, AMM; Vignali, C1
Belbachir, N; Kitani, T; Lam, CK; Ma, N; Rhee, JW; Shrestha, R; Tian, L; Wnorowski, A; Wu, JC1
Catterall, WA; Gamal El-Din, TM; Lenaeus, MJ; Tang, L; Zheng, N1
Ataei-Pirkooh, A; Bokharaei-Salim, F; Esghaei, M; Farahmand, M; Ghorbani, S; Habib, Z; Keyvani, H; Khales, P; Khanaliha, K; Kiani, SJ; Monavari, SH; Saghafi, MM; Sayyahfar, S; Tavakoli, A1
Elton, A; Kwa, M; Singh, J1
Castagnetti, V; Palazzoli, F; Profeta, C; Santunione, AL; Silingardi, E; Vandelli, D; Verri, P1

Reviews

13 review(s) available for diltiazem and amlodipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Usefulness of amlodipine for angina pectoris.
    The American journal of cardiology, 1994, Jan-27, Volume: 73, Issue:3

    Topics: Amlodipine; Angina Pectoris; Angina Pectoris, Variant; Cardiac Output; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Exercise; Humans; Male; Myocardial Ischemia; Nadolol; Randomized Controlled Trials as Topic

1994
Nisoldipine CC: clinical experience in ischaemic heart disease.
    Cardiology, 1997, Volume: 88 Suppl 1

    Topics: Amlodipine; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Humans; Myocardial Ischemia; Nisoldipine; Randomized Controlled Trials as Topic

1997
Patterns of compliance with once versus twice daily antihypertensive drug therapy in primary care: a randomized clinical trial using electronic monitoring.
    The Canadian journal of cardiology, 1997, Volume: 13, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Canada; Diltiazem; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Patient Compliance; Primary Health Care

1997
Calcium channel blockers in left ventricular dysfunction or congestive heart failure.
    Connecticut medicine, 1997, Volume: 61, Issue:10

    Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Felodipine; Heart Failure; Humans; Nicardipine; Nifedipine; Ventricular Dysfunction, Left; Verapamil

1997
Calcium channel blocker-induced protection against cardiovascular damage.
    International journal of cardiology, 1997, Dec-31, Volume: 62 Suppl 2

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Cardiovirus Infections; Cytokines; Diltiazem; Encephalomyocarditis virus; Heart Failure; Humans; Mice; Myocarditis; Nitric Oxide; RNA, Messenger

1997
Accelerated arteriosclerosis after transplantation: the possible role of calcium channel blockers.
    International journal of cardiology, 1997, Dec-31, Volume: 62 Suppl 2

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Artery Disease; Coronary Vessels; Diltiazem; Drug Therapy, Combination; Heart Transplantation; Humans

1997
Anti-anginal and anti-ischemic effects of mibefradil, a new T-type calcium channel antagonist.
    Cardiology, 1998, Volume: 89 Suppl 1

    Topics: Adolescent; Adult; Amlodipine; Angina Pectoris; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Male; Mibefradil; Middle Aged; Myocardial Ischemia; Safety; Tetrahydronaphthalenes

1998
Mibefradil, a T-type channel-selective calcium antagonist: clinical trials in chronic stable angina pectoris.
    American journal of hypertension, 1998, Volume: 11, Issue:4 Pt 3

    Topics: Amlodipine; Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Chronic Disease; Clinical Trials as Topic; Diltiazem; Humans; Mibefradil; Tetrahydronaphthalenes

1998
Raynaud's phenomenon (primary).
    Clinical evidence, 2003, Issue:9

    Topics: Amlodipine; Diltiazem; Humans; Nafronyl; Nicardipine; Nifedipine; Raynaud Disease; Vasodilator Agents

2003
ST-segment analysis in ambulatory ECG (AECG or Holter) monitoring in patients with coronary artery disease: clinical significance and analytic techniques.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2005, Volume: 10, Issue:2

    Topics: Adrenergic beta-Antagonists; Amlodipine; Cardiovascular Agents; Coronary Artery Disease; Diltiazem; Drug Therapy, Combination; Electrocardiography, Ambulatory; Humans; Hypolipidemic Agents; Prognosis; Randomized Controlled Trials as Topic; Signal Processing, Computer-Assisted; Treatment Outcome

2005
Prognostic effects of calcium channel blockers in patients with vasospastic angina--a meta-analysis.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:9

    Topics: Amlodipine; Angina Pectoris; Asian People; Calcium Channel Blockers; Coronary Vasospasm; Dihydropyridines; Diltiazem; Humans; Nifedipine; Prognosis; Treatment Outcome

2010
Comparison of various calcium antagonist on vasospastic angina: a systematic review.
    Open heart, 2023, Volume: 10, Issue:1

    Topics: Adult; Amlodipine; Calcium; Calcium Channel Blockers; Coronary Vasospasm; Diltiazem; Humans; Nifedipine; Observational Studies as Topic; Quality of Life

2023

Trials

32 trial(s) available for diltiazem and amlodipine

ArticleYear
Open comparative study to assess the efficacy and safety of two calcium antagonists, amlodipine and diltiazem, in the treatment of symptomatic myocardial ischaemia.
    Postgraduate medical journal, 1991, Volume: 67 Suppl 5

    Topics: Amlodipine; Angina Pectoris; Coronary Disease; Diltiazem; Hemodynamics; Humans; Middle Aged; Nifedipine; Nitroglycerin

1991
An exercise hemodynamic comparison of verapamil, diltiazem, and amlodipine in coronary artery disease.
    Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:2

    Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Cardiac Output; Coronary Disease; Diltiazem; Exercise; Hemodynamics; Humans; Middle Aged; Nifedipine; Prospective Studies; Rest; Verapamil

1990
Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:4

    Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiazem; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Nisoldipine; Prospective Studies; Random Allocation; Verapamil

1987
Electrophysiologic effects of amlodipine vs. diltiazem in patients with coronary artery disease and beta-blocking therapy.
    Cardiovascular drugs and therapy, 1994, Volume: 8, Issue:4

    Topics: Adult; Aged; Amlodipine; Atenolol; Coronary Disease; Diltiazem; Drug Therapy, Combination; Electrophysiology; Female; Heart; Humans; Hypertension; Male; Middle Aged; Myocardial Ischemia

1994
Usefulness of amlodipine for angina pectoris.
    The American journal of cardiology, 1994, Jan-27, Volume: 73, Issue:3

    Topics: Amlodipine; Angina Pectoris; Angina Pectoris, Variant; Cardiac Output; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Exercise; Humans; Male; Myocardial Ischemia; Nadolol; Randomized Controlled Trials as Topic

1994
Comparison of the effects of amlodipine and diltiazem on 24-hour blood pressure, plasma catecholamines, and left ventricular mass.
    The American journal of cardiology, 1996, Jul-15, Volume: 78, Issue:2

    Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Catecholamines; Diltiazem; Female; Heart Rate; Heart Ventricles; Humans; Hypertrophy, Left Ventricular; Male; Middle Aged; Ventricular Function, Left

1996
[Evaluation of amlodipine in stable effort angina. Comparison with diltiazem in terms of efficacy, tolerability and maintenance of the anti-ischemic action 24 hours after the last dose].
    Annales de cardiologie et d'angeiologie, 1996, Volume: 45, Issue:2

    Topics: Adult; Aged; Amlodipine; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Diltiazem; Exercise Test; Heart Rate; Humans; Male; Middle Aged; Physical Exertion; Vasodilator Agents

1996
Persistence of anti-hypertensive effect after 'missed doses' of calcium antagonist with long (amlodipine) vs short (diltiazem) elimination half-life.
    British journal of clinical pharmacology, 1996, Volume: 41, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Drug Administration Schedule; Female; Half-Life; Humans; Male; Middle Aged; Placebos

1996
Mibefradil in the treatment of systemic hypertension: comparative studies with other calcium antagonists.
    The American journal of cardiology, 1997, Aug-21, Volume: 80, Issue:4B

    Topics: Adult; Aged; Amlodipine; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Edema; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Leg; Male; Mibefradil; Middle Aged; Nifedipine; Tetrahydronaphthalenes

1997
Mibefradil in the treatment of chronic stable angina pectoris: comparative studies with other calcium antagonists.
    The American journal of cardiology, 1997, Aug-21, Volume: 80, Issue:4B

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Chronic Disease; Diltiazem; Female; Hemodynamics; Humans; Male; Mibefradil; Middle Aged; Nitroglycerin; Tetrahydronaphthalenes

1997
Patterns of compliance with once versus twice daily antihypertensive drug therapy in primary care: a randomized clinical trial using electronic monitoring.
    The Canadian journal of cardiology, 1997, Volume: 13, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Canada; Diltiazem; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Patient Compliance; Primary Health Care

1997
Comparison of amlodipine and long-acting diltiazem in the treatment of mild or moderate hypertension.
    American journal of hypertension, 1997, Volume: 10, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diltiazem; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Patient Compliance; Patient Dropouts

1997
A placebo-controlled comparison of diltiazem and amlodipine monotherapy in essential hypertension using 24-h ambulatory monitoring.
    Blood pressure, 1998, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Myocardium; Organ Size

1998
Anti-anginal and anti-ischemic effects of mibefradil, a new T-type calcium channel antagonist.
    Cardiology, 1998, Volume: 89 Suppl 1

    Topics: Adolescent; Adult; Amlodipine; Angina Pectoris; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Male; Mibefradil; Middle Aged; Myocardial Ischemia; Safety; Tetrahydronaphthalenes

1998
Amlodipine versus diltiazem as additional antianginal treatment to atenolol. Centralised European Studies in Angina Research (CESAR) Investigators.
    The American journal of cardiology, 1998, Jan-15, Volume: 81, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Amlodipine; Angina Pectoris; Atenolol; Calcium Channel Blockers; Coronary Angiography; Diltiazem; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography, Ambulatory; Exercise Test; Female; Follow-Up Studies; Hemodynamics; Humans; Male; Middle Aged; Safety; Treatment Outcome

1998
A comparative study of once-daily amlodipine versus twice-daily diltiazem controlled release (CR) in the treatment of stable angina pectoris. Amlodipine Study Group.
    Cardiovascular drugs and therapy, 1998, Volume: 12 Suppl 3

    Topics: Adult; Aged; Amlodipine; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Administration Schedule; Exercise Test; Female; Humans; Male; Middle Aged

1998
Combination of calcium channel blockers and beta-adrenoceptor blockers for patients with exercise-induced angina pectoris: a double-blind parallel-group comparison of different classes of calcium channel blockers. Netherlands Working Group on Cardiovascul
    British journal of clinical pharmacology, 1999, Volume: 47, Issue:5

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angina Pectoris; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dizziness; Double-Blind Method; Drug Therapy, Combination; Exercise; Exercise Test; Female; Heart Rate; Hemodynamics; Humans; Male; Mibefradil; Middle Aged; Risk Assessment; Tetrahydronaphthalenes

1999
Combination of calcium channel blockers and beta blockers for patients with exercise-induced angina pectoris: a double-blind parallel-group comparison of different classes of calcium channel blockers. The Netherlands Working Group on Cardiovascular Resear
    Angiology, 1999, Volume: 50, Issue:6

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angina Pectoris; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dizziness; Double-Blind Method; Drug Combinations; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Mibefradil; Middle Aged; Myocardial Ischemia; Physical Exertion; Tetrahydronaphthalenes; Time Factors

1999
Combination of calcium channel blockers and beta-blockers for patients with exercise-induced angina pectoris: beneficial effect of calcium channel blockers largely determined by their effect on heart rate.
    Journal of clinical pharmacology, 1999, Volume: 39, Issue:7

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Death, Sudden; Diltiazem; Dizziness; Double-Blind Method; Drug Therapy, Combination; Exercise; Exercise Test; Female; Heart Rate; Humans; Male; Mibefradil; Middle Aged; Regression Analysis; Tetrahydronaphthalenes; Treatment Outcome

1999
The pharmacokinetics of extended-release formulations of calcium antagonists and of amlodipine in subjects with different gastrointestinal transit times.
    Journal of clinical pharmacology, 1999, Volume: 39, Issue:10

    Topics: Adult; Amlodipine; Area Under Curve; Biological Availability; Calcium Channel Blockers; Cross-Over Studies; Delayed-Action Preparations; Diltiazem; Felodipine; Female; Gastrointestinal Diseases; Gastrointestinal Transit; Headache; Humans; Male; Middle Aged; Time Factors

1999
[Calcium channel blocking agents and albuminuria in diabetic and hypertensive patients. A pilot study].
    Archives des maladies du coeur et des vaisseaux, 2000, Volume: 93, Issue:8

    Topics: Absorption; Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Creatinine; Diabetes Complications; Diltiazem; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hypertension; Kidney Glomerulus; Kidney Tubules; Middle Aged; Pilot Projects; Plasma Volume; Pressure; Prospective Studies; Radiopharmaceuticals; Technetium Tc 99m Aggregated Albumin

2000
Influence of diltiazem on the pharmacokinetics of amlodipine in elderly hypertensive patients.
    European journal of clinical pharmacology, 2001, Volume: 57, Issue:1

    Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Diltiazem; Humans; Hypertension

2001
A randomized, double-blind comparison of the efficacy and tolerability of once-daily modified-release diltiazem capsules with once-daily amlodipine tablets in patients with stable angina.
    Journal of cardiovascular pharmacology, 2001, Volume: 38, Issue:3

    Topics: Adult; Aged; Amlodipine; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cardiovascular Agents; Diltiazem; Double-Blind Method; Drug Administration Schedule; Exercise Tolerance; Female; Heart Rate; Humans; Male; Middle Aged; Nitroglycerin; Time Factors; Treatment Outcome; Vasodilator Agents

2001
Effect of sildenafil on blood pressure and arterial wave reflection in treated hypertensive men.
    Journal of human hypertension, 2001, Volume: 15, Issue:10

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Diltiazem; Diuretics; Drug Interactions; Erectile Dysfunction; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Pulsatile Flow; Purines; Receptors, Angiotensin; Sildenafil Citrate; Single-Blind Method; Sulfones

2001
[Effects of long-acting calcium antagonists--amlodipine and diltiazem in patients with stable angina of effort: comparative randomized controlled trial].
    Terapevticheskii arkhiv, 2001, Volume: 73, Issue:9

    Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Exercise Test; Humans; Male; Middle Aged

2001
Medical treatment of myocardial ischemia in coronary artery disease: effect of drug regime and irregular dosing in the CAPE II trial.
    Journal of the American College of Cardiology, 2002, Sep-04, Volume: 40, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Amlodipine; Atenolol; Calcium Channel Blockers; Cardiovascular Agents; Coronary Disease; Diltiazem; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Humans; Isosorbide; Male; Middle Aged; Myocardial Ischemia

2002
Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial.
    JAMA, 2004, Jan-21, Volume: 291, Issue:3

    Topics: Acetanilides; Adrenergic beta-Antagonists; Aged; Amlodipine; Angina Pectoris; Atenolol; Calcium Channel Blockers; Cardiovascular Agents; Chronic Disease; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Physical Exertion; Piperazines; Ranolazine; Survival Analysis

2004
Antihypertensive efficacy of night-time graded-release diltiazem versus morning amlodipine in African Americans.
    American journal of hypertension, 2004, Volume: 17, Issue:9

    Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Black or African American; Blood Pressure; Circadian Rhythm; Delayed-Action Preparations; Diltiazem; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Treatment Outcome

2004
Pharmacokinetic interactions between indinavir plus ritonavir and calcium channel blockers.
    Clinical pharmacology and therapeutics, 2005, Volume: 78, Issue:2

    Topics: Adolescent; Adult; Amlodipine; Calcium Channel Blockers; Diltiazem; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Hypertension; Indinavir; Male; Middle Aged; Ritonavir

2005
An 8-week double-blind study of amlodipine and diltiazem in patients with stable exertional angina pectoris.
    Journal of cardiovascular pharmacology, 1991, Volume: 17 Suppl 1

    Topics: Adult; Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Exercise Test; Female; Humans; Male; Middle Aged; Nitroglycerin; Physical Exertion; Time Factors; Treatment Outcome; Vasodilator Agents

1991
Open comparative study to assess the efficacy and safety of two calcium antagonists: amlodipine and diltiazem in the treatment of symptomatic myocardial ischemia.
    Journal of cardiovascular pharmacology, 1991, Volume: 17 Suppl 1

    Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Diltiazem; Drug Administration Schedule; Female; Heart Rate; Humans; Male; Middle Aged; Myocardial Ischemia; Treatment Outcome

1991
Cutaneous adverse reactions to calcium channel blockers.
    Asian Pacific journal of allergy and immunology, 2014, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Amlodipine; Calcium Channel Blockers; Diltiazem; Drug Eruptions; Female; Humans; Male; Middle Aged

2014

Other Studies

78 other study(ies) available for diltiazem and amlodipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Oral Therapy with Amlodipine and Lacidipine, 1,4-Dihydropyridine Derivatives Showing Activity against Experimental Visceral Leishmaniasis.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1

    Topics: Administration, Oral; Amlodipine; Animals; Antiprotozoal Agents; Dihydropyridines; Leishmania donovani; Leishmaniasis, Visceral; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Parasitic Sensitivity Tests; Treatment Outcome

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Cholesterol alters the binding of Ca2+ channel blockers to the membrane lipid bilayer.
    Molecular pharmacology, 1992, Volume: 41, Issue:2

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cell Membrane; Cholesterol; Dihydropyridines; Diltiazem; Electrons; Isradipine; Lipid Bilayers; Myocardium; Nifedipine; Nimodipine; Nitrendipine; Phosphatidylcholines; Rabbits; Verapamil

1992
Inhibition of cancer cell growth by calcium channel antagonists in the athymic mouse.
    Cancer research, 1992, May-01, Volume: 52, Issue:9

    Topics: Amlodipine; Animals; Breast Neoplasms; Calcium; Calcium Channel Blockers; Cell Division; Culture Media; Diltiazem; DNA, Neoplasm; Drug Screening Assays, Antitumor; Mice; Mice, Nude; Nifedipine; Tumor Cells, Cultured; Verapamil

1992
The hemodynamic effects of lacidipine in anesthetized dogs: comparison with nitrendipine, amlodipine, verapamil, and diltiazem.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:3

    Topics: Amlodipine; Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Diltiazem; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Stroke Volume; Vascular Resistance; Verapamil

1991
Hemodynamic profile of Ro 40-5967 in conscious rats: comparison with diltiazem, verapamil, and amlodipine.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 10

    Topics: Amlodipine; Animals; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Hemodynamics; Male; Mibefradil; Nifedipine; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Verapamil

1991
All calcium channel blockers are not alike.
    International journal of cardiology, 1991, Volume: 32, Issue:2

    Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Felodipine; Heart Failure; Humans; Nifedipine

1991
Natriuretic activity of amlodipine, diltiazem, and nitrendipine in saline-loaded anesthetized dogs.
    Journal of cardiovascular pharmacology, 1988, Volume: 12 Suppl 7

    Topics: Amlodipine; Anesthesia; Animals; Calcium Channel Blockers; Diltiazem; Dogs; Female; Hemodynamics; Natriuresis; Nifedipine; Nitrendipine; Sodium; Time Factors

1988
Verapamil is a potent inhibitor of 5-HT-induced platelet aggregation.
    Thrombosis research, 1989, Jul-15, Volume: 55, Issue:2

    Topics: Adenosine Diphosphate; Amlodipine; Calcium Channel Blockers; Collagen; Diltiazem; Epinephrine; Humans; In Vitro Techniques; Nifedipine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin Antagonists; Verapamil

1989
A hemodynamic comparison of verapamil, diltiazem, and amlodipine in coronary artery disease.
    American heart journal, 1989, Volume: 118, Issue:5 Pt 2

    Topics: Amlodipine; Calcium Channel Blockers; Coronary Disease; Diltiazem; Female; Hemodynamics; Humans; Male; Middle Aged; Nifedipine; Physical Exertion; Rest; Verapamil

1989
Effect of calcium channel blockers on the growth of human vascular smooth muscle cells derived from saphenous vein and vascular graft stenoses.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:5

    Topics: Amlodipine; Cell Division; Cells, Cultured; Diltiazem; DNA; Graft Occlusion, Vascular; Humans; L-Lactate Dehydrogenase; Muscle, Smooth, Vascular; Saphenous Vein; Verapamil

1994
Protective effect of some calcium antagonists against mitochondrial calcium injury.
    International journal of tissue reactions, 1994, Volume: 16, Issue:5-6

    Topics: Adenosine Triphosphate; Amlodipine; Animals; Antihypertensive Agents; Bepridil; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Male; Mitochondria, Liver; Myocardial Ischemia; Nicardipine; Rats; Rats, Wistar; Verapamil

1994
Investigation and optimisation of the use of micellar electrokinetic chromatography for the analysis of six cardiovascular drugs.
    Journal of chromatography. A, 1995, May-12, Volume: 700, Issue:1-2

    Topics: Amlodipine; Atenolol; Cardiovascular Agents; Chromatography; Diltiazem; Electrochemistry; Hydrogen-Ion Concentration; Kinetics; Micelles; Nicardipine; Nifedipine; Osmosis; Sodium Dodecyl Sulfate; Verapamil

1995
In vitro antioxidant activity of calcium antagonists against LDL oxidation compared with alpha-tocopherol.
    Biochemical and biophysical research communications, 1994, Sep-30, Volume: 203, Issue:3

    Topics: Adult; Amlodipine; Antioxidants; Calcium Channel Blockers; Copper; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Humans; Isradipine; Lipoproteins, LDL; Oxidation-Reduction; Reference Values; Thiobarbituric Acid Reactive Substances; Verapamil; Vitamin E

1994
Dermatologic cross-sensitivity between diltiazem and amlodipine.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:1

    Topics: Amlodipine; Diltiazem; Diphenhydramine; Drug Eruptions; Humans; Hydroxyzine; Male; Methylprednisolone; Middle Aged; Pruritus

1994
Effects of amlodipine versus diltiazem on morning peak in myocardial ischemic activity in angina pectoris.
    The American journal of cardiology, 1993, Nov-15, Volume: 72, Issue:15

    Topics: Aged; Amlodipine; Angina Pectoris; Circadian Rhythm; Diltiazem; Female; Humans; Male; Middle Aged; Myocardial Ischemia

1993
Long-term hemodynamic effects at rest and during exercise of newer antihypertensive agents and salt restriction in essential hypertension: review of epanolol, doxazosin, amlodipine, felodipine, diltiazem, lisinopril, dilevalol, carvedilol, and ketanserin.
    Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:2

    Topics: Adult; Amlodipine; Antihypertensive Agents; Benzeneacetamides; Carbazoles; Carvedilol; Diet, Sodium-Restricted; Diltiazem; Dipeptides; Doxazosin; Exercise; Felodipine; Female; Hemodynamics; Humans; Hypertension; Ketanserin; Labetalol; Lisinopril; Longitudinal Studies; Male; Middle Aged; Propanolamines

1993
Effects of semotiadil, a novel Ca2+ channel antagonist, on the electrical activity of Langendorff-perfused guinea pig hearts in comparison with diltiazem, amlodipine and nifedipine.
    European journal of pharmacology, 1995, Nov-03, Volume: 286, Issue:1

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Electrocardiography; Female; Guinea Pigs; Heart Conduction System; Heart Rate; In Vitro Techniques; Male; Nifedipine; Thiazoles

1995
Ca2+ channel blockers modulate metabolism of collagens within the extracellular matrix.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11

    Topics: Amlodipine; Becaplermin; Calcium Channel Blockers; Cells, Cultured; Collagen; Collagenases; Dihydropyridines; Diltiazem; Enzyme Activation; Extracellular Matrix; Felodipine; Fibroblasts; Humans; Kinetics; Lung; Metalloendopeptidases; Muscle, Smooth, Vascular; Nitrobenzenes; Piperazines; Platelet-Derived Growth Factor; Procollagen; Proline; Proto-Oncogene Proteins c-sis; Transcription, Genetic; Verapamil

1996
Amlodipine releases nitric oxide from canine coronary microvessels: an unexpected mechanism of action of a calcium channel-blocking agent.
    Circulation, 1998, Feb-17, Volume: 97, Issue:6

    Topics: Amlodipine; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Dogs; Dose-Response Relationship, Drug; Enalaprilat; In Vitro Techniques; Male; Nitric Oxide; Ramipril; Regression Analysis

1998
Catalepsy induced by calcium channel blockers in mice.
    Biopharmaceutics & drug disposition, 1998, Volume: 19, Issue:2

    Topics: Amlodipine; Animals; Binding, Competitive; Calcium Channel Blockers; Catalepsy; Dihydropyridines; Diltiazem; Disease Models, Animal; Flunarizine; Male; Mice; Muscarinic Antagonists; Nitrobenzenes; Piperazines; Predictive Value of Tests; Receptors, Cholinergic; Receptors, Dopamine D1; Receptors, Dopamine D2; Scopolamine; Time Factors; Verapamil

1998
Amlodipine versus diltiazem CR in the reduction of the total ischemic burden: the Circadian Anti-Ischemia Program in Europe (CAPE) II trial--clinical rationale and methodology.
    Cardiovascular drugs and therapy, 1998, Volume: 12 Suppl 3

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Circadian Rhythm; Delayed-Action Preparations; Diltiazem; Europe; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Research Design

1998
Rational use of calcium-channel antagonists in Raynaud's phenomenon.
    Current opinion in rheumatology, 1998, Volume: 10, Issue:6

    Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Felodipine; Humans; Isradipine; Nicardipine; Nifedipine; Raynaud Disease

1998
Effects of Ca2+ channel blockers on apomorphine, bromocriptine and morphine-induced locomotor activity in mice.
    European journal of pharmacology, 1999, Jan-08, Volume: 364, Issue:2-3

    Topics: Amlodipine; Animals; Apomorphine; Benzazepines; Bromocriptine; Calcium Channel Blockers; Diltiazem; Dopamine Antagonists; Female; Haloperidol; Heterocyclic Compounds, 4 or More Rings; Mice; Morphine; Motor Activity; Nicardipine; Time Factors; Verapamil

1999
Prevalence of gingival overgrowth induced by calcium channel blockers: a community-based study.
    Journal of periodontology, 1999, Volume: 70, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Analysis of Variance; Calcium Channel Blockers; Dental Plaque Index; Diltiazem; Dose-Response Relationship, Drug; England; Female; Gingival Hyperplasia; Gingivitis; Humans; Logistic Models; Male; Middle Aged; Nifedipine; Periodontal Index; Prevalence; Sex Ratio; Time Factors

1999
Membrane antioxidant effects of the charged dihydropyridine calcium antagonist amlodipine.
    Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Antioxidants; Calcium; Calorimetry, Differential Scanning; Diltiazem; Dimyristoylphosphatidylcholine; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Inhibitory Concentration 50; Lipid Peroxidation; Phosphatidylcholines; Verapamil

1999
Long-term preservation of left ventricular function in medically treated patients with coronary artery disease and persistent exercise-induced ischemia.
    Cardiologia (Rome, Italy), 1999, Volume: 44, Issue:3

    Topics: Aged; Amlodipine; Anti-Arrhythmia Agents; Atenolol; Cardiovascular Agents; Coronary Disease; Data Interpretation, Statistical; Diastole; Diltiazem; Drug Therapy, Combination; Echocardiography; Electrocardiography, Ambulatory; Exercise Test; Follow-Up Studies; Humans; Middle Aged; Nifedipine; Nitrates; Stroke Volume; Systole; Time Factors; Vasodilator Agents; Ventricular Function, Left

1999
Immunomodulating effects of second-generation calcium channel blockers on experimental heart transplantation.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1999, Volume: 31, Issue:3

    Topics: Adjuvants, Immunologic; Amlodipine; Animals; Benzimidazoles; Calcium Channel Blockers; Cyclosporine; Diltiazem; Drug Therapy, Combination; Felodipine; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Male; Mibefradil; Rats; Rats, Inbred Lew; Tetrahydronaphthalenes; Time Factors

1999
Antioxidant properties of calcium antagonists related to membrane biophysical interactions.
    The American journal of cardiology, 1999, Aug-19, Volume: 84, Issue:4A

    Topics: Amlodipine; Animals; Antioxidants; Calcium Channel Blockers; Calorimetry, Differential Scanning; Diltiazem; Dose-Response Relationship, Drug; Intracellular Membranes; Lipid Peroxidation; Male; Microsomes, Liver; Radioligand Assay; Rats; Rats, Sprague-Dawley; Verapamil; X-Ray Diffraction

1999
Low-dose calcium antagonists reduce energy demand and cellular damage of isolated hearts during both ischemia and reperfusion.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:3

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dose-Response Relationship, Drug; Energy Metabolism; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nifedipine; Purines; Pyruvates

1999
Calcium channel blockers and mortality in elderly patients with myocardial infarction.
    Archives of internal medicine, 1999, Oct-25, Volume: 159, Issue:19

    Topics: Aged; Aged, 80 and over; Amlodipine; Bepridil; Calcium Channel Blockers; Diltiazem; Female; Humans; Logistic Models; Male; Myocardial Infarction; Nifedipine; Retrospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome; United States; Verapamil

1999
N-Type calcium channels control sympathetic neurotransmission in human heart atrium.
    Circulation, 2000, Feb-01, Volume: 101, Issue:4

    Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Calcium Channels, N-Type; Diltiazem; Electric Stimulation; Female; Heart; Heart Atria; Humans; Male; Mibefradil; Middle Aged; Norepinephrine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Sympathetic Nervous System; Synaptic Transmission; Verapamil

2000
Differential effects of calcium channel antagonists in the amelioration of radial artery vasospasm.
    The Annals of thoracic surgery, 2000, Volume: 69, Issue:4

    Topics: Amlodipine; Calcium Channel Blockers; Coronary Artery Bypass; Diltiazem; Female; Humans; Male; Middle Aged; Nifedipine; Radial Artery; Vasoconstriction

2000
Ca2+-agonistic effect of a T-type Ca-channel blocker mibefradil (Ro 40-5967).
    Membrane & cell biology, 2000, Volume: 13, Issue:5

    Topics: Amlodipine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Cells, Cultured; Coronary Vessels; Diltiazem; Mibefradil; Muscle, Smooth, Vascular; Swine; Verapamil

2000
Amlodipine inhibits thapsigargin-sensitive CA(2+) stores in thrombin-stimulated vascular smooth muscle cells.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:3

    Topics: Amlodipine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium-Transporting ATPases; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Enzyme Inhibitors; Intracellular Fluid; Isradipine; Muscle, Smooth, Vascular; Potassium Chloride; Rats; Rats, Inbred WKY; Sarcoplasmic Reticulum; Signal Transduction; Thapsigargin; Thrombin; Verapamil

2000
Retrospective evaluation of the conversion of amlodipine to alternative calcium channel blockers.
    Pharmacotherapy, 2000, Volume: 20, Issue:9

    Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Diltiazem; Felodipine; Female; Humans; Hypertension; Male; Nifedipine; Retrospective Studies

2000
Amlodipine increases nitric oxide synthesis in cytokine-stimulated cultured vascualar smooth muscle cells.
    Journal of hypertension, 2000, Volume: 18, Issue:11

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Animals; Aorta, Thoracic; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Diltiazem; Gene Expression Regulation, Enzymologic; Interleukin-1; Muscle, Smooth, Vascular; NF-kappa B; Nifedipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Sprague-Dawley; RNA, Messenger

2000
Nifedipine inhibits activation of transcription factor NF-kappaB.
    Life sciences, 2000, Oct-13, Volume: 67, Issue:21

    Topics: Amlodipine; Calcium Channel Blockers; Cell Migration Inhibition; Diltiazem; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Interleukin-1; Lipopolysaccharides; Luciferases; Lung Neoplasms; Lymphocyte Activation; Macrophages; NF-kappa B; Nifedipine; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Verapamil

2000
Successful management of intractable coronary spasm with a coronary stent.
    Japanese circulation journal, 2000, Volume: 64, Issue:11

    Topics: Adult; Amlodipine; Aspirin; Calcium Channel Blockers; Cardiovascular Agents; Coronary Angiography; Coronary Artery Disease; Coronary Vasospasm; Diltiazem; Doxazosin; Drug Resistance; Drug Therapy, Combination; Ergonovine; Humans; Isosorbide Dinitrate; Male; Myocardial Infarction; Nicorandil; Nitrates; Pyridines; Stents; Ticlopidine; Ventricular Fibrillation

2000
Potential role of eNOS in the therapeutic control of myocardial oxygen consumption by ACE inhibitors and amlodipine.
    Cardiovascular research, 2001, Volume: 49, Issue:1

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Carbachol; Cardiotonic Agents; Culture Techniques; Diltiazem; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred C57BL; Myocardium; Nitric Oxide Donors; Nitric Oxide Synthase; Oxygen Consumption; Ramipril; S-Nitroso-N-Acetylpenicillamine; Substance P; Vasodilator Agents

2001
Calcium-dependent effects of melatonin inhibition of glutamatergic response in rat striatum.
    Journal of neuroendocrinology, 2001, Volume: 13, Issue:5

    Topics: Amlodipine; Animals; Anticonvulsants; Biological Transport; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Corpus Striatum; Diltiazem; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Ionophores; Iontophoresis; Male; Melatonin; omega-Conotoxins; Rats; Rats, Wistar; Synaptosomes; Tritium

2001
Cutaneous drug reaction case reports: from the world literature.
    American journal of clinical dermatology, 2001, Volume: 2, Issue:4

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Aged; Amlodipine; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Anticonvulsants; Antihypertensive Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antirheumatic Agents; BCG Vaccine; Cefotetan; Cephamycins; Contrast Media; Cysteine; Dapsone; Diltiazem; Dipyrone; Docetaxel; Drug Eruptions; Echinacea; Enoxaparin; Female; Fructose; Glucans; Glucose; Gold Sodium Thiomalate; Humans; Ibuprofen; Icodextrin; Ioxaglic Acid; Male; Middle Aged; Minocycline; Paclitaxel; Pregnancy; Solvents; Taxoids; Topiramate; Triamcinolone; Trichloroethylene

2001
Cardiomyocyte intracellular calcium and cardiac dysfunction after burn trauma.
    Critical care medicine, 2002, Volume: 30, Issue:1

    Topics: Amiloride; Amlodipine; Animals; Burns; Calcium; Calcium Channel Blockers; Dantrolene; Diltiazem; Myocardial Contraction; Myocardium; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium; Tumor Necrosis Factor-alpha; Ventricular Function, Left

2002
Preventing radial artery spasm.
    The Annals of thoracic surgery, 2002, Volume: 73, Issue:5

    Topics: Amlodipine; Arteries; Coronary Vasospasm; Diltiazem; Humans; Nifedipine; Organ Culture Techniques; Radial Artery

2002
Antiplatelet activity of semotiadil fumarate.
    Thrombosis research, 2002, May-15, Volume: 106, Issue:4-5

    Topics: Adenosine Diphosphate; Adult; Amlodipine; Calcium Channel Blockers; Case-Control Studies; Collagen; Diltiazem; Humans; Hypertension; Middle Aged; Nifedipine; Platelet Aggregation; Platelet Aggregation Inhibitors; Thiazoles

2002
Parkinsonian syndrome and calcium channel blockers.
    Prescrire international, 2003, Volume: 12, Issue:64

    Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Humans; Parkinsonian Disorders; Verapamil

2003
Different effects of calcium channel blockers on matrix metalloproteinase-2 expression in cultured rat cardiac fibroblasts.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:2

    Topics: Amlodipine; Animals; Animals, Newborn; Benzoquinones; Calcium; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fibroblasts; Genistein; Lactams, Macrocyclic; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Myocardium; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide; Nitroprusside; Protein Kinase Inhibitors; Quinones; Rats; Rats, Wistar; Rifabutin; Verapamil

2004
Evaluation of a technique of inducing hypertensive renal insufficiency in cats.
    American journal of veterinary research, 2004, Volume: 65, Issue:7

    Topics: Amlodipine; Analysis of Variance; Animals; Blood Pressure; Blood Pressure Determination; Cat Diseases; Cats; Diltiazem; Enalapril; Heart Rate; Hypertension, Renal; Infarction; Kidney; Ligation; Losartan; Nephrectomy; Renal Insufficiency; Telemetry; Time Factors

2004
[Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina. Results of CARISA].
    Kardiologiia, 2004, Volume: 44, Issue:3

    Topics: Acetanilides; Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Atenolol; Cardiovascular Agents; Chronic Disease; Diltiazem; Double-Blind Method; Exercise Test; Humans; Multicenter Studies as Topic; Piperazines; Placebos; Randomized Controlled Trials as Topic; Ranolazine; Time Factors; Vasodilator Agents

2004
Adult hypertension: reducing cardiovascular morbidity and mortality.
    Prescrire international, 2005, Volume: 14, Issue:75

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Alcohol Drinking; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Complications; Diltiazem; Diuretics; Drug Evaluation; Health Behavior; Humans; Hypertension; Losartan; Obesity; Renal Insufficiency; Sodium; Stroke; Verapamil

2005
Two cases of Brugada syndrome associated with spontaneous clinical episodes of coronary vasospasm.
    Internal medicine (Tokyo, Japan), 2006, Volume: 45, Issue:2

    Topics: Acetylcholine; Amlodipine; Calcium Channel Blockers; Cardiovascular Agents; Coronary Vasospasm; Defibrillators, Implantable; Diltiazem; Electric Countershock; Electrocardiography; Fatal Outcome; Heart Function Tests; Humans; Male; Middle Aged; Myocardial Ischemia; Syncope; Ventricular Fibrillation

2006
The use of vasopressin in the setting of recalcitrant hypotension due to calcium channel blocker overdose.
    Clinical toxicology (Philadelphia, Pa.), 2007, Volume: 45, Issue:1

    Topics: Adult; Amlodipine; Antidotes; Blood Pressure; Calcium Channel Blockers; Diazepam; Diltiazem; Drug Overdose; Drug Therapy, Combination; Female; Humans; Hypotension; Middle Aged; Treatment Outcome; Vasoconstrictor Agents; Vasopressins

2007
Effects of benidipine and some other calcium channel blockers on the prognosis of patients with vasospastic angina. Cohort study with evaluation of the ergonovine coronary spasm induction test.
    Arzneimittel-Forschung, 2007, Volume: 57, Issue:9

    Topics: Adult; Aged; Aging; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Cohort Studies; Coronary Angiography; Coronary Stenosis; Coronary Vasospasm; Diabetes Complications; Dihydropyridines; Diltiazem; Ergonovine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nifedipine; Oxytocics; Prognosis; Risk Factors

2007
Prognostic effects of benidipine in patients with vasospastic angina: comparison with diltiazem and amlodipine.
    Journal of cardiovascular pharmacology, 2008, Volume: 51, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Diseases; Cohort Studies; Coronary Vasospasm; Dihydropyridines; Diltiazem; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multivariate Analysis; Prognosis; Retrospective Studies; Risk Factors

2008
Effects of amlodipine, diltiazem, and verapamil on the anticonvulsant action of topiramate against maximal electroshock-induced seizures in mice.
    Canadian journal of physiology and pharmacology, 2008, Volume: 86, Issue:3

    Topics: Amlodipine; Animals; Anticonvulsants; Behavior, Animal; Brain; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Electroshock; Fluorescence Polarization Immunoassay; Fructose; Mice; Motor Skills; Seizures; Topiramate; Verapamil

2008
Calcium channel blockers differentially modulate cytokine production by peripheral blood mononuclear cells.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:3

    Topics: Amlodipine; Calcium Channel Blockers; Cytokines; Diltiazem; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-1alpha; Interleukin-1beta; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Nifedipine; Tumor Necrosis Factor-alpha; Verapamil

2010
Effects of calcium antagonists and agonists on isolated human v. saphena magna used for coronary artery bypass grafting and guinea pig's papillary muscle.
    Arzneimittel-Forschung, 2011, Volume: 61, Issue:7

    Topics: Action Potentials; Adult; Aged; Aged, 80 and over; Amlodipine; Animals; Benzimidazoles; Calcium Channel Agonists; Calcium Channel Blockers; Coronary Artery Bypass; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; In Vitro Techniques; Isometric Contraction; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Papillary Muscles; Phenylephrine; Saphenous Vein; Vasoconstrictor Agents

2011
Action of calcium antagonists and agonists on isolated human thoracic arteries used for coronary artery bypass grafting.
    Pharmacological reports : PR, 2012, Volume: 64, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Benzimidazoles; Calcium Channel Agonists; Calcium Channel Blockers; Carbachol; Coronary Artery Bypass; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Pyridines; Thoracic Arteries

2012
The role of external Ca²⁺ in the action of Ca²⁺-channel agonists and antagonists on isolated human thoracic arteries.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2014, Volume: 65, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Benzimidazoles; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Female; Humans; In Vitro Techniques; Isometric Contraction; Male; Middle Aged; Milrinone; Thoracic Arteries

2014
Degradation kinetics and pathways of three calcium channel blockers under UV irradiation.
    Water research, 2015, Dec-01, Volume: 86

    Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Disinfection; Kinetics; Photolysis; Ultraviolet Rays; Verapamil; Wastewater; Water Pollutants, Chemical

2015
Two Fatal Cases Involving Cardiovascular Drugs Diltiazem and Amlodipine.
    Journal of analytical toxicology, 2018, Jan-01, Volume: 42, Issue:1

    Topics: Amlodipine; Autopsy; Calcium Channel Blockers; Cause of Death; Chromatography, Liquid; Diltiazem; Drug Overdose; Fatal Outcome; Female; Humans; Male; Medication Adherence; Middle Aged; Spectrometry, Mass, Electrospray Ionization; Suicide; Tandem Mass Spectrometry

2018
Identifying the Transcriptome Signatures of Calcium Channel Blockers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
    Circulation research, 2019, 07-05, Volume: 125, Issue:2

    Topics: Amlodipine; Calcium Channel Blockers; Cell Differentiation; Cells, Cultured; Diltiazem; Humans; Induced Pluripotent Stem Cells; Myocytes, Cardiac; Myosin Heavy Chains; Nifedipine; Transcriptome; Verapamil

2019
Structural Basis for Diltiazem Block of a Voltage-Gated Ca
    Molecular pharmacology, 2019, Volume: 96, Issue:4

    Topics: Allosteric Regulation; Amlodipine; Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Crystallography, X-Ray; Diltiazem; Humans; Models, Molecular; Protein Conformation; Verapamil

2019
Amlodipine and Diltiazem Significantly Repress Human Rotavirus Infection
    Recent advances in anti-infective drug discovery, 2023, Volume: 18, Issue:3

    Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Humans; Rotavirus; Rotavirus Infections

2023
Cardiovascular drugs and suicide death: Determination of carvedilol, amlodipine, doxazosin and diltiazem in two fatal cases.
    Journal of pharmaceutical and biomedical analysis, 2024, Jan-20, Volume: 238

    Topics: Amlodipine; Cardiovascular Agents; Carvedilol; Diltiazem; Doxazosin; Humans; Suicide

2024