Page last updated: 2024-08-23

diltiazem and amiloride

diltiazem has been researched along with amiloride in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19903 (9.09)18.7374
1990's16 (48.48)18.2507
2000's10 (30.30)29.6817
2010's4 (12.12)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Horiguchi, M; Kuriyama, S; Nakamura, K; Sakai, O; Uchida, H1
Kurihara, K; Shoji, T1
Rabkin, SW1
Breitbart, H; Cragoe, EJ; Lardy, HA1
Miller, RC; Schoeffter, P1
Fujino, Y; Fujiwara, A; Komukai, M; Yasumasu, I1
LaBelle, EF; Rex, KA; Sordahl, LA1
Czarnowska, E; Karwatowska-Prokopczuk, E; Prokopczuk, A1
Gielow, ML; Gu, GG; Singh, S1
de Haan, HP; Lie, KI; May, JF; Saleh, AE; van Boven, AJ; van Gilst, WH1
Matthews, HR; McLatchie, LM1
Concha, J; Contreras, E; Contreras, G; Norris, B1
Ciampolillo, F; Green, RB; Stanton, BA; Vandorpe, DH1
Gomez, MP; Nasi, E1
Cox, TC1
Chopra, M; Eberl, DF; Hall, LM; Ren, D; Xu, H1
Fitz, JG; Garnovskaya, MN; Liddle, RA; Prpic, V; Raymond, JR; Wang, Y1
Czarnowska, E; Karwatowska-Prokopczuk, E; Kurzydlowski, K1
Duszyk, M; Thethi, K1
Kleene, SJ1
Folkesson, HG; Guggino, SE; Lu, LN; Matthay, MA; Norlin, A1
Horton, JW; Maass, DL; Sanders, B; White, DJ1
White, WB1
Dhalla, NS; Rathi, SS; Saini, HK; Xu, YJ1
Cheng, HW; Cheng, YW; Hu, CM; Kang, JJ; Liao, JW1
Amtorp, O; Christensen, S; Jonassen, TE; Müllertz, KM; Pedersen, LR1
Dupré, G; Fischer, B; Fischer, H; Hazemi, P; Lemmens-Gruber, R; Lucas, R; Pietschmann, H; Prymaka, V; Shabbir, W; Tzotzos, S1

Reviews

2 review(s) available for diltiazem and amiloride

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Clinical trial experience around the globe: focus on calcium-channel blockers.
    Clinical cardiology, 2003, Volume: 26, Issue:2 Suppl 2

    Topics: Amiloride; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Clinical Trials as Topic; Diabetic Angiopathies; Diltiazem; Humans; Hypertension; Meta-Analysis as Topic; Nifedipine; Stroke

2003

Trials

1 trial(s) available for diltiazem and amiloride

ArticleYear
Hypertension and left ventricular hypertrophy in black people.
    Journal of human hypertension, 1995, Volume: 9, Issue:3

    Topics: Amiloride; Black People; Diltiazem; Diuretics; Double-Blind Method; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male

1995

Other Studies

30 other study(ies) available for diltiazem and amiloride

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Decreased insulin-sensitive Ca2+ transport in cultured vascular smooth muscle cells from spontaneously hypertensive rats.
    American journal of hypertension, 1992, Volume: 5, Issue:12 Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cells, Cultured; Diltiazem; Gallic Acid; Homeostasis; Hypertension; Insulin; Isoquinolines; Male; Muscle, Smooth, Vascular; Piperazines; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1992
Sensitivity and transduction mechanisms of responses to general odorants in turtle vomeronasal system.
    The Journal of general physiology, 1991, Volume: 98, Issue:5

    Topics: Amiloride; Animals; Chemoreceptor Cells; Chlorides; Cilia; Diltiazem; Dose-Response Relationship, Drug; Odorants; Olfactory Bulb; Olfactory Pathways; Signal Transduction; Sodium Chloride; Sulfates; Turtles; Verapamil

1991
The effect of alteration of extracellular Na+ or Ca2+ and inhibition of Ca2+ entry, Na(+)-H+ exchange, and Na(+)-Ca2+ exchange by diltiazem, amiloride, and dichlorobenzamil on the response of cardiac cell aggregates to epidermal growth factor.
    Experimental cell research, 1990, Volume: 188, Issue:2

    Topics: Amiloride; Animals; Calcium; Calcium Channels; Carrier Proteins; Cell Aggregation; Cells, Cultured; Chick Embryo; Diltiazem; Epidermal Growth Factor; Myocardial Contraction; Myocardium; Sodium; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers

1990
Stimulation of Ca2+ uptake into epididymal bull spermatozoa by analogues of amiloride.
    European journal of biochemistry, 1990, Sep-11, Volume: 192, Issue:2

    Topics: Amiloride; Animals; Calcium; Cattle; Cell Membrane; Diltiazem; Epididymis; Filipin; Kinetics; Male; Nifedipine; Sodium; Spermatozoa; Structure-Activity Relationship

1990
Role of sodium-calcium exchange and effects of calcium entry blockers on endothelial-mediated responses in rat isolated aorta.
    Molecular pharmacology, 1986, Volume: 30, Issue:1

    Topics: Amiloride; Animals; Aorta; Bepridil; Calcium; Calcium Channel Blockers; Choline; Cyclic GMP; Diltiazem; Endothelium; Female; Lithium; Muscle, Smooth, Vascular; Nicergoline; Nifedipine; Pyrrolidines; Rats; Rats, Inbred Strains; Reserpine; Sodium; Verapamil

1986
The effects of several ion channel blockers and calmodulin antagonists on fertilization-induced acid release and 45Ca2+ uptake in sea urchin eggs.
    Experimental cell research, 1985, Volume: 159, Issue:2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Benzazepines; Calcium; Calmodulin; Diltiazem; Female; Fertilization; Hydrogen; Ovum; Sea Urchins; Verapamil

1985
Amiloride and diltiazem inhibition of microsomal and mitochondrial Na+ and Ca2+ transport.
    The American journal of physiology, 1984, Volume: 246, Issue:1 Pt 1

    Topics: Amiloride; Animals; Benzazepines; Biological Transport, Active; Calcium; Diltiazem; Intracellular Membranes; Kidney Medulla; Kinetics; Membrane Potentials; Microsomes; Mitochondria, Heart; Pyrazines; Rabbits; Sodium

1984
Combined therapy with dimethylthiourea, diltiazem and amiloride/dimethylamiloride in the ischemic/reperfused heart.
    Cardiovascular research, 1995, Volume: 30, Issue:1

    Topics: Amiloride; Animals; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endocardium; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Thiourea

1995
Resolution and pharmacological analysis of the voltage-dependent calcium channels of Drosophila larval muscles.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:9

    Topics: Amiloride; Animals; Calcium Channels; Dihydropyridines; Diltiazem; Drosophila melanogaster; Electrophysiology; Larva; Verapamil

1995
The effect of pH on the block by L-cis-diltiazem and amiloride of the cyclic GMP-activated conductance of salamander rods.
    Proceedings. Biological sciences, 1994, Mar-22, Volume: 255, Issue:1344

    Topics: Ambystoma; Amiloride; Animals; Cyclic GMP; Cytoplasm; Diltiazem; Electric Conductivity; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Membrane Potentials; Retinal Rod Photoreceptor Cells; Rod Cell Outer Segment; Time Factors

1994
Calcium channel blockers apparently decrease noradrenaline release from nerve-skin terminals in Caudiverbera caudiverbera.
    General pharmacology, 1993, Volume: 24, Issue:4

    Topics: Amiloride; Animals; Anura; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Electric Stimulation; Electrophysiology; In Vitro Techniques; Membrane Potentials; Nerve Endings; Nifedipine; Norepinephrine; Skin; Skin Physiological Phenomena; Synapses; Verapamil

1993
Cyclic nucleotide-gated cation channels mediate sodium absorption by IMCD (mIMCD-K2) cells.
    The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 1

    Topics: Amiloride; Amino Acid Sequence; Animals; Biological Transport, Active; Calcium; Clone Cells; Cyclic GMP; Diltiazem; Ion Channel Gating; Ion Channels; Kidney Medulla; Kidney Tubules, Collecting; Magnesium; Membrane Potentials; Mice; Molecular Sequence Data; Nucleotides, Cyclic; Patch-Clamp Techniques; Sodium; Sodium Channels

1997
Antagonists of the cGMP-gated conductance of vertebrate rods block the photocurrent in scallop ciliary photoreceptors.
    The Journal of physiology, 1997, Apr-15, Volume: 500 ( Pt 2)

    Topics: Amiloride; Animals; Calcium Channel Blockers; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Electric Conductivity; Ion Channel Gating; Mollusca; Patch-Clamp Techniques; Photoreceptor Cells, Invertebrate; Retinal Rod Photoreceptor Cells

1997
Apical regulation of nonselective cation channels by ATP in larval bullfrog skin.
    The Journal of experimental zoology, 1997, Oct-15, Volume: 279, Issue:3

    Topics: Acetylcholine; Adenosine Triphosphate; Amiloride; Animals; Atropine; Calcium; Calcium Channels; Diltiazem; Egtazic Acid; Electric Conductivity; In Vitro Techniques; Larva; Potassium Chloride; Rana catesbeiana; Receptors, Purinergic P2; Skin Physiological Phenomena; Sulfonamides; Suramin

1997
A mutation affecting dihydropyridine-sensitive current levels and activation kinetics in Drosophila muscle and mammalian heart calcium channels.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Apr-01, Volume: 18, Issue:7

    Topics: Amiloride; Amino Acid Sequence; Animals; Biological Transport; Calcium Channel Blockers; Calcium Channels; Cysteine; Dihydropyridines; Diltiazem; Diuretics; Drosophila melanogaster; Electric Conductivity; Gene Expression; Kinetics; Larva; Mammals; Molecular Sequence Data; Muscles; Mutagenesis; Myocardium; Oocytes; Patch-Clamp Techniques; Point Mutation; Rabbits; Xenopus

1998
Inhibition of Na+/H+ exchange stimulates CCK secretion in STC-1 cells.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Amiloride; Animals; Antigens, Polyomavirus Transforming; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Membrane; Cell Membrane Permeability; Cholecystokinin; Diltiazem; Hydrogen-Ion Concentration; Insulin; Intestinal Neoplasms; Mice; Mice, Transgenic; Polyomavirus; Potassium; Potassium Channels; Promoter Regions, Genetic; Rats; Simian virus 40; Sodium; Sodium-Hydrogen Exchangers

1998
Ultrastructural study of calcium shift in ischemic/reperfused rat heart under treatment with dimethylthiourea, diltiazem and amiloride.
    Basic research in cardiology, 1998, Volume: 93, Issue:4

    Topics: Amiloride; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Free Radical Scavengers; Heart; Hydroxyl Radical; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Wistar; Sarcolemma; Sodium-Hydrogen Exchangers; Thiourea

1998
Nitric oxide inhibits whole-cell current in cystic fibrosis pancreatic epithelial cells.
    Pancreas, 1999, Volume: 19, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Calcium Channel Blockers; Cell Line; Charybdotoxin; Cyclic AMP; Cyclic GMP; Cystic Fibrosis; Diltiazem; Enzyme Inhibitors; Epithelial Cells; Glutathione; Humans; Membrane Potentials; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Pancreas; Patch-Clamp Techniques; Penicillamine; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione

1999
Spontaneous gating of olfactory cyclic-nucleotide-gated channels.
    The Journal of membrane biology, 2000, Nov-01, Volume: 178, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Cations, Divalent; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Electric Conductivity; Electrophysiology; Enzyme Inhibitors; Ion Channel Gating; Ion Channels; Magnesium; Neurons; Olfactory Mucosa; Rana pipiens; Second Messenger Systems; Sodium Channel Blockers; Sulfonamides

2000
Contribution of amiloride-insensitive pathways to alveolar fluid clearance in adult rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 90, Issue:4

    Topics: Adrenergic beta-Agonists; Amiloride; Animals; Body Fluids; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Diltiazem; Hemodynamics; Ion Channels; Male; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Terbutaline; Vasodilator Agents

2001
Cardiomyocyte intracellular calcium and cardiac dysfunction after burn trauma.
    Critical care medicine, 2002, Volume: 30, Issue:1

    Topics: Amiloride; Amlodipine; Animals; Burns; Calcium; Calcium Channel Blockers; Dantrolene; Diltiazem; Myocardial Contraction; Myocardium; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium; Tumor Necrosis Factor-alpha; Ventricular Function, Left

2002
Mechanisms of low Na+-induced increase in intracellular calcium in KCl-depolarized rat cardiomyocytes.
    Molecular and cellular biochemistry, 2004, Volume: 263, Issue:1-2

    Topics: Amiloride; Animals; Calcium; Calcium Channels, L-Type; Diltiazem; Fluorescent Dyes; Fura-2; In Vitro Techniques; Intracellular Fluid; Male; Membrane Potentials; Myocytes, Cardiac; Nickel; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Sodium; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Verapamil

2004
Induction of contracture and extracellular Ca2+ influx in cardiac muscle by sanguinarine: a study on cardiotoxicity of sanguinarine.
    Journal of biomedical science, 2005, Volume: 12, Issue:2

    Topics: Alkaloids; Amiloride; Animals; Antioxidants; Benzophenanthridines; Calcium; Calcium Channels; Cardiotonic Agents; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Egtazic Acid; Heart; Heart Ventricles; Isoquinolines; Lanthanum; Lipid Peroxidation; Male; Manganese; Myocardium; Nickel; Nifedipine; Rats; Rats, Wistar; Time Factors; Verapamil

2005
Enhanced alveolar fluid clearance following 72 h of continuous isoproterenol infusion in rats.
    Acta physiologica (Oxford, England), 2012, Volume: 206, Issue:2

    Topics: Adrenergic beta-Agonists; Albumins; Amiloride; Animals; Blotting, Western; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Dose-Response Relationship, Drug; Epithelial Sodium Channels; Infusion Pumps, Implantable; Infusions, Subcutaneous; Isoproterenol; Male; Permeability; Pulmonary Alveoli; Rats; Rats, Wistar; Respiration, Artificial; Sodium Channel Blockers; Time Factors

2012
AP301, a synthetic peptide mimicking the lectin-like domain of TNF, enhances amiloride-sensitive Na(+) current in primary dog, pig and rat alveolar type II cells.
    Pulmonary pharmacology & therapeutics, 2013, Volume: 26, Issue:3

    Topics: Amiloride; Animals; Cell Line, Tumor; Diltiazem; Dogs; Dose-Response Relationship, Drug; Epithelial Sodium Channels; Lectins; Peptides, Cyclic; Pulmonary Alveoli; Rats; Swine; Tumor Necrosis Factor-alpha; Zinc

2013