Page last updated: 2024-08-23

diltiazem and alprostadil

diltiazem has been researched along with alprostadil in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's9 (52.94)18.2507
2000's2 (11.76)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Finn, JC; Pearl, RG1
Francis, GS; Johnson, GJ; Leis, LA1
Miwa, K; Toda, N1
Kawashima, A; Koike, H; Nishio, S; Ueno, Y1
Hibi, M; Iwase, J; Kawamura, M; Murakami, F; Usui, A; Yoshida, K1
Fukasawa, M; Fukui, K; Hirooka, S; Kohi, M; Orita, H; Uchino, H; Washio, M2
Reinecke, P; Sandmann, W; Szabo, Z; Torsello, G1
Kojima, M; Miyakawa, T; Ui, M1
Kusumoto, K; Notodihardjo, HW; Ogawa, Y1
Az-Ma, T; Saeki, N; Yuge, O1

Other Studies

17 other study(ies) available for diltiazem and alprostadil

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Hemodynamic effects of diltiazem during vasoconstrictor pulmonary hypertension in sheep.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:5

    Topics: Alprostadil; Animals; Diltiazem; Hemodynamics; Hypertension, Pulmonary; Male; Nifedipine; Sheep; Vasodilator Agents

1990
Adenosine potentiates the inhibitory effects of calcium channel antagonists on human platelet aggregation induced by thromboxane A2 or U46619.
    Thrombosis research, 1990, Jul-01, Volume: 59, Issue:1

    Topics: Adenosine; Alprostadil; Calcium Channel Blockers; Diltiazem; Drug Synergism; Epinephrine; Humans; In Vitro Techniques; Nifedipine; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2; Verapamil

1990
The regional difference of relaxations induced by various vasodilators in isolated dog coronary and mesenteric arteries.
    Japanese journal of pharmacology, 1985, Volume: 38, Issue:3

    Topics: Adenosine; Alprostadil; Animals; Coronary Vessels; Diltiazem; Dogs; Epoprostenol; Female; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Nitroprusside; Thromboxane A2; Vasodilator Agents

1985
Effect of beraprost sodium, a stable prostacyclin analogue, on pulmonary thromboembolism in mice.
    Thrombosis research, 1995, Jan-15, Volume: 77, Issue:2

    Topics: Administration, Oral; Alprostadil; Animals; Aspirin; Bridged Bicyclo Compounds; Collagen; Diltiazem; Drug Evaluation, Preclinical; Epinephrine; Epoprostenol; Fatty Acids, Monounsaturated; Fibrinolytic Agents; Heparin; Hydralazine; Injections, Intravenous; Isosorbide Dinitrate; Male; Mice; Nifedipine; Nitroprusside; Platelet Aggregation Inhibitors; Pulmonary Embolism; Superoxide Dismutase; Vasodilator Agents

1995
The effects of calcium antagonists and prostaglandin E1 on isolated canine coronary arterial tension.
    Surgery today, 1994, Volume: 24, Issue:12

    Topics: Alprostadil; Animals; Calcium; Calcium Channel Blockers; Coronary Vessels; Data Interpretation, Statistical; Diltiazem; Dogs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Potassium; Sodium; Solutions; Verapamil

1994
In vitro evaluation of nicorandil, diltiazem, and prostaglandin E1 on hypothermic injury to immature myocytes.
    The Journal of surgical research, 1995, Volume: 58, Issue:3

    Topics: Alprostadil; Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cold Temperature; Creatine Kinase; Diltiazem; Female; Heart Rate; Heart Ventricles; L-Lactate Dehydrogenase; Myocardium; Niacinamide; Nicorandil; Rats; Rats, Wistar; Ventricular Function

1995
Cytoprotective effects of nicorandil on hypothermic injury to immature cardiac myocytes--comparison with nitroglycerin, diltiazem and prostaglandin E1.
    Japanese circulation journal, 1994, Volume: 58, Issue:8

    Topics: Alprostadil; Animals; Cells, Cultured; Cold Temperature; Creatine Kinase; Cryopreservation; Cryoprotective Agents; Diltiazem; Heart; L-Lactate Dehydrogenase; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Rats; Vasodilator Agents

1994
[The role of pharmacologic kidney protection in preventing post-ischemic renal failure in animal experiment].
    Zentralblatt fur Chirurgie, 1993, Volume: 118, Issue:7

    Topics: Acute Kidney Injury; Alprostadil; Animals; Creatinine; Diltiazem; Dogs; Drug Therapy, Combination; Ischemia; Kidney; Kidney Function Tests; Renal Circulation; Superoxide Dismutase; Vascular Resistance; Water-Electrolyte Balance

1993
Differential routes of Ca2+ influx in Swiss 3T3 fibroblasts in response to receptor stimulation.
    The Biochemical journal, 1998, Jan-01, Volume: 329 ( Pt 1)

    Topics: 3T3 Cells; Alprostadil; Angiotensin II; Animals; Arachidonic Acid; Bombesin; Bradykinin; Calcium; Calcium Channel Blockers; Diltiazem; Endothelins; Enzyme Activation; GTP-Binding Proteins; Inositol Phosphates; Mice; Nifedipine; Pertussis Toxin; Phospholipases A; Phospholipases A2; Platelet-Derived Growth Factor; Protein Kinase C; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Vasopressins; Virulence Factors, Bordetella

1998
The blood flow patterns of microsurgical procedures in rats with topical and systemic vasodilators.
    Scandinavian journal of plastic and reconstructive surgery and hand surgery, 1998, Volume: 32, Issue:3

    Topics: Administration, Topical; Alprostadil; Analysis of Variance; Anastomosis, Surgical; Anesthetics, Local; Animals; Chlorpromazine; Diltiazem; Dopamine Antagonists; Femoral Artery; Laser-Doppler Flowmetry; Lidocaine; Male; Microsurgery; Rats; Rats, Wistar; Regional Blood Flow; Vasodilator Agents

1998
Differential action of spasmolytic vasodilators on platelet aggregation and endothelial cell-dependent anti-aggregation.
    Acta anaesthesiologica Scandinavica, 2000, Volume: 44, Issue:4

    Topics: Alprostadil; Animals; Aorta; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Nicardipine; Nitroglycerin; Nitroprusside; Papaverine; Pentobarbital; Platelet Aggregation; Platelet Aggregation Inhibitors; Swine; Sympatholytics; Vasodilator Agents

2000