diltiazem has been researched along with allopurinol in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (25.00) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 7 (25.00) | 29.6817 |
| 2010's | 7 (25.00) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Mielke, W; Pethö-Schramm, A; Schmidt, G; Vetterlein, F | 1 |
| Auch-Schwelk, W; Katusic, ZS; Vanhoutte, PM | 1 |
| Murata, K; Noda, K; Samejima, M; Tagawa, K | 1 |
| Bergmann, SR; Koller, PT | 1 |
| Robak, J; Shridi, F | 1 |
| Burghardt, B; Janero, DR; Lopez, R | 1 |
| Kohno, K; Murata, K; Noda, K; Samejima, M | 1 |
| Burris, KD; Conroy, WG; Isom, GE; Johnson, JD | 1 |
| Di Giacomo, C; La Delfa, C; Perez-Polo, JR; Renis, M; Russo, A; Sorrenti, V; Vanella, A | 1 |
| Brezina, A; Kolin, A; Mamelak, M; Pandula, E | 1 |
| Bertuglia, S; Colantuoni, A; Intaglietta, M | 1 |
| Gurbel, PA; Herzog, WR; Serebruany, VL | 1 |
| Obata, T; Yamanaka, Y | 1 |
| Lähteenvuo, M; Lintunen, J; Taipale, H; Tanskanen, A; Tiihonen, J | 1 |
1 review(s) available for diltiazem and allopurinol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
27 other study(ies) available for diltiazem and allopurinol
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effects of diltiazem and allopurinol in postischemic microcirculatory changes in the rat kidney.
Topics: Allopurinol; Animals; Capillaries; Capillary Permeability; Diltiazem; Drug Interactions; Erythrocyte Aggregation; Globulins; Kidney; Male; Microcirculation; Rats; Rats, Inbred Strains; Regional Blood Flow; Reperfusion Injury; Time Factors | 1991 |
Contractions to oxygen-derived free radicals are augmented in aorta of the spontaneously hypertensive rat.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Allopurinol; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Diltiazem; Endothelium, Vascular; Free Radicals; Hypertension; Male; Oxygen; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction; Xanthine Oxidase | 1989 |
Pharmacokinetic analysis of single- or multiple-dose plasma drug concentration data with a microcomputer using multi-fraction absorption models.
Topics: Administration, Oral; Allopurinol; Bayes Theorem; Cimetidine; Delayed-Action Preparations; Diltiazem; Intestinal Absorption; Microcomputers; Models, Biological; Nalidixic Acid; Pharmaceutical Preparations; Pharmacokinetics; Regression Analysis; Software; Sulfisoxazole | 1989 |
Reduction of lipid peroxidation in reperfused isolated rabbit hearts by diltiazem.
Topics: Animals; Coronary Disease; Diltiazem; Heart; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kinetics; Lipid Peroxidation; Male; Malonates; Malondialdehyde; Myocardial Reperfusion; Myocardium; Rabbits; Xanthine Oxidase | 1989 |
The influence of calcium channel blockers on superoxide anions.
Topics: Animals; Anions; Calcium Channel Blockers; Diltiazem; Fendiline; Free Radicals; In Vitro Techniques; Microsomes, Liver; Nifedipine; Oxidation-Reduction; Rats; Superoxides; Verapamil; Xanthine Oxidase | 1988 |
Protection of cardiac membrane phospholipid against oxidative injury by calcium antagonists.
Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Heart; In Vitro Techniques; Lipid Peroxides; Male; Membrane Lipids; Myocardium; Nifedipine; Phospholipids; Rats; Verapamil; Xanthine Oxidase | 1988 |
Pharmacokinetic analysis of concentration data of drugs with irregular absorption profiles using multi-fraction absorption models.
Topics: Allopurinol; Animals; Diltiazem; Dogs; Humans; Intestinal Absorption; Kinetics; Male; Models, Biological; Pharmaceutical Preparations; Pindolol; Sulfisoxazole | 1987 |
Peroxidation of brain lipids following cyanide intoxication in mice.
Topics: Allopurinol; Animals; Brain; Calcium; Cyanides; Diltiazem; Dose-Response Relationship, Drug; Lipid Peroxides; Male; Mice; Xanthine Oxidase | 1987 |
Lipid peroxidation and survival in rats following cerebral post-ischaemic reperfusion: effect of drugs with different molecular mechanisms.
Topics: Allopurinol; Animals; Antioxidants; Brain Ischemia; Deferoxamine; Diltiazem; Lipid Peroxidation; Male; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury; Verapamil; Vitamin E | 1994 |
Morphometry of reversible myocardial damage.
Topics: Allopurinol; Animals; Cardiomyopathies; Cytoplasm; Diltiazem; Gerbillinae; Hydroxybutyrates; Isoproterenol; Lipid Metabolism; Male; Myocardium | 1994 |
Effect of leukocyte adhesion and microvascular permeability on capillary perfusion during ischemia-reperfusion injury in hamster cheek pouch.
Topics: Adenosine; Allopurinol; Animals; Capillary Permeability; Cell Adhesion; Cheek; Cricetinae; Diltiazem; Leukocytes; Male; Mesocricetus; Perfusion; Pyrazoles; Reperfusion Injury; Verapamil | 1993 |
Serial changes of natural antithrombotics during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor.
Topics: Animals; Antithrombins; Diltiazem; Heart; Macrophage-1 Antigen; Magnesium; Myocardial Infarction; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Swine; Xanthine Oxidase | 1996 |
Protective effect of diltiazem on myocardial ischemic injury associated with .OH generation.
Topics: Allopurinol; Animals; Calcium Channel Blockers; Diltiazem; Heart Rate; Hydroxybenzoates; Hydroxyl Radical; Male; Myocardial Reperfusion Injury; Norepinephrine; Rats; Rats, Wistar; Salicylates; Salicylic Acid; Xanthine; Xanthine Oxidase; Xanthines | 1997 |
Allopurinol, dipyridamole and calcium channel blockers in the treatment of bipolar disorder - A nationwide cohort study.
Topics: Adenosine; Allopurinol; Bipolar Disorder; Calcium Channel Blockers; Cohort Studies; Dihydropyridines; Diltiazem; Dipyridamole; Humans | 2022 |