Page last updated: 2024-08-23

diltiazem and adenosine diphosphate

diltiazem has been researched along with adenosine diphosphate in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199022 (66.67)18.7374
1990's6 (18.18)18.2507
2000's4 (12.12)29.6817
2010's1 (3.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inamasu, M; Morita, T; Sasaki, Y; Shinjo, A1
Ashikawa, K; Bing, RJ; Weishaar, R1
Baydoun, AR; Markham, A; Morgan, RM; Sweetman, AJ1
Belousov, IuB; Leonova, MV; Rumiantsev, DO1
Furui, H; Furumichi, T; Hayashi, H; Saito, H; Suzuki, T; Yamada, Y; Yamauchi, K; Yokota, M1
Falotico, R; Fuller, BL; Moore, JB; Tolman, EL1
Glusa, E1
Bevan, J; Glusa, E; Heptinstall, S1
Gutkin, AB; Khudiakova, ND; Leonova, MV; Razumov, VB1
Johnson, PC; Salzman, EW; Smith, M; Ware, JA1
Corrigan, JJ; Fenster, PE; Ring, ME2
Harwell, T; Maiorano, P; Watts, J1
Altin, JG; Bygrave, FL1
Furui, H; Sotobata, I; Taniguchi, N; Yamauchi, K1
Maiorano, LJ; Maiorano, PC; Watts, JA1
Alusík, S; Hrcková, Y; Kubis, M; Oral, I1
Honn, KV; Onoda, JM; Sloane, BF1
Brigmon, L; Mehta, J; Mehta, P; Ostrowski, N1
Cremer, KF; Joyal, M; Mehta, J; Pieper, JA1
Horwitz, PM; Kadowitz, PJ; Landry, AZ; Lippton, HL; McNamara, DB1
Bando, H; Tsubura, E; Yamashita, T1
Blackburn, KJ; Higgins, AJ1
Kiyomoto, A; Morita, T; Odawara, A; Sasaki, Y1
Kimura, M; Ono, H1
Akhavan, MM; Dehpour, AR; Delfan, A; Meysamee, F; Samadian, T1
Altman, R; Budd, SE; Chernoff, SB; Dollar, LE; Zucker, ML1
Kikuchi, K; Sugawara, H; Tobise, K1
Doi, H; Ikeo, T; Karasawa, T; Katoh, M; Narita, H; Odawara, A; Takagi, M1
Kritz, H; Oguogho, A; Sinzinger, H; Wolfram, RM1
Casley, WL; Ding, L; Yeung, P1
Tang, SW; Wang, HT; Wu, XL; Wu, YL; Zhang, HX; Zhang, YF; Zhu, HM1
Cheng, KT; Huang, Y; Kwan, HY; Ma, Y; Tang, NL; Yao, X; Yu, S1

Trials

2 trial(s) available for diltiazem and adenosine diphosphate

ArticleYear
Antiplatelet effects of oral diltiazem, propranolol, and their combination.
    British journal of clinical pharmacology, 1987, Volume: 24, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Diltiazem; Drug Interactions; Epinephrine; Humans; Male; Platelet Aggregation Inhibitors; Propranolol; Thromboxane A2

1987
Effect of diltiazem and low-dose aspirin on platelet aggregation and ATP release induced by paired agonists.
    Thrombosis and haemostasis, 1993, Aug-02, Volume: 70, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Arachidonic Acid; Aspirin; Bleeding Time; Blood Platelets; Diltiazem; Drug Synergism; Epinephrine; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors

1993

Other Studies

31 other study(ies) available for diltiazem and adenosine diphosphate

ArticleYear
In vitro effect of the coronary vasodilator diltiazem on human and rabbit platelets.
    Thrombosis research, 1978, Volume: 13, Issue:6

    Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Benzazepines; Blood Platelets; Calcium; Collagen; Diltiazem; Egtazic Acid; Humans; Indomethacin; Male; Platelet Aggregation; Rabbits; Vasodilator Agents

1978
Effect of diltiazem, a calcium antagonist, on myocardial ischemia.
    The American journal of cardiology, 1979, Volume: 43, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzazepines; Blood Pressure; Calcium; Coronary Disease; Diltiazem; Dogs; Drug Evaluation, Preclinical; Fatty Acids, Nonesterified; Glycolysis; Heart Rate; Lactates; Mitochondria, Heart; Myocardial Contraction; Myocardium; Oxygen Consumption; Phosphocreatine

1979
Bay K 8644, modifier of calcium transport and energy metabolism in rat heart mitochondria: a new intracellular site of action.
    British journal of pharmacology, 1990, Volume: 101, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Diphosphate; Animals; Biological Transport, Active; Calcium; Diltiazem; Energy Metabolism; Female; Glutamates; In Vitro Techniques; Malates; Mitochondria, Heart; NAD; Nitrendipine; Oxidation-Reduction; Oxygen Consumption; Rats; Ruthenium Red; Verapamil

1990
[Various aspects of the anti-aggregatory action of diltiazem and cordaphene in patients with ischemic heart disease].
    Kardiologiia, 1991, Volume: 31, Issue:3

    Topics: Adenosine Diphosphate; Adult; Aged; Coronary Disease; Diltiazem; Erythrocyte Membrane; Hemolysis; Humans; Middle Aged; Nifedipine; Platelet Aggregation; Platelet Aggregation Inhibitors

1991
Inhibitory effects of endothelial cells and calcium channel blockers on platelet aggregation.
    Japanese heart journal, 1990, Volume: 31, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Aspirin; Blood Platelets; Bone Marrow Cells; Calcium Channel Blockers; Collagen; Diltiazem; Endothelium, Vascular; Epoprostenol; Fibroblasts; Humans; Nicardipine; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Thromboxane A2; Verapamil

1990
Inhibition of rabbit platelet phosphodiesterase activity and aggregation by calcium channel blockers.
    Thrombosis research, 1985, Nov-01, Volume: 40, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Diphosphate; Animals; Blood Platelets; Calcium Channel Blockers; Cytosol; Diltiazem; Kinetics; Nifedipine; Platelet Aggregation; Rabbits; Structure-Activity Relationship; Verapamil

1985
Effect of verapamil on platelet aggregation.
    Folia haematologica (Leipzig, Germany : 1928), 1988, Volume: 115, Issue:4

    Topics: Adenosine Diphosphate; Collagen; Cyproheptadine; Diltiazem; Epinephrine; Humans; In Vitro Techniques; Platelet Aggregation; Serotonin; Verapamil

1988
Verapamil is a potent inhibitor of 5-HT-induced platelet aggregation.
    Thrombosis research, 1989, Jul-15, Volume: 55, Issue:2

    Topics: Adenosine Diphosphate; Amlodipine; Calcium Channel Blockers; Collagen; Diltiazem; Epinephrine; Humans; In Vitro Techniques; Nifedipine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin Antagonists; Verapamil

1989
[Effect of diltiazem on the functional activity of erythrocytes and thrombocytes in patients with ischemic heart disease].
    Kardiologiia, 1989, Volume: 29, Issue:10

    Topics: Adenosine Diphosphate; Adult; Aged; Calcium; Coronary Disease; Diltiazem; Erythrocytes; Female; Hemolysis; Humans; Male; Middle Aged; Platelet Aggregation

1989
Inhibition of human platelet aggregation and cytoplasmic calcium response by calcium antagonists: studies with aequorin and quin2.
    Circulation research, 1986, Volume: 59, Issue:1

    Topics: Adenosine Diphosphate; Aequorin; Aminoquinolines; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Calcium; Calcium Channel Blockers; Culture Media; Cytoplasm; Diglycerides; Diltiazem; Epinephrine; Fluorescent Dyes; Humans; Luminescent Proteins; Nifedipine; Platelet Aggregation; Thrombin; Verapamil

1986
Comparison of the effects of bepridil and diltiazem upon globally ischemic rat hearts.
    European journal of pharmacology, 1987, Jan-28, Volume: 134, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bepridil; Calcium; Coronary Disease; Diltiazem; Heart; Hemodynamics; In Vitro Techniques; Mitochondria, Heart; Myocardium; Oxygen Consumption; Perfusion; Pyrrolidines; Rats; Rats, Inbred Strains

1987
The influx of Ca2+ induced by the administration of glucagon and Ca2+-mobilizing agents to the perfused rat liver could involve at least two separate pathways.
    The Biochemical journal, 1987, Feb-15, Volume: 242, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Diltiazem; Epidermal Growth Factor; Glucagon; Liver; Male; Neomycin; Nifedipine; Perfusion; Rats; Rats, Inbred Strains; Verapamil

1987
Effects of diltiazem hydrochloride on cardiovascular response, platelet aggregation and coagulating activity during exercise testing in systemic hypertension.
    The American journal of cardiology, 1986, Mar-01, Volume: 57, Issue:8

    Topics: Adenosine Diphosphate; Adult; Antithrombin III; Benzazepines; Blood Coagulation; Cardiovascular System; Diltiazem; Exercise Test; Female; Fibrinogen; Heart Rate; Humans; Hypertension; Male; Middle Aged; Partial Thromboplastin Time; Platelet Aggregation; Prothrombin Time; Renin

1986
Effects of oral diltiazem on platelet function: alone and in combination with "low dose" aspirin.
    Thrombosis research, 1986, Nov-01, Volume: 44, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Administration, Oral; Aspirin; Bleeding Time; Blood Platelets; Diltiazem; Epinephrine; Humans; Male; Platelet Aggregation; Thromboxane A2

1986
Comparison of the protective effects of verapamil, diltiazem, nifedipine, and buffer containing low calcium upon global myocardial ischemic injury.
    Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzazepines; Blood Pressure; Buffers; Calcium; Coronary Disease; Diltiazem; Heart Rate; Myocardial Contraction; Nifedipine; Perfusion; Phosphocreatine; Rats; Verapamil

1986
[The antiaggregation effect of diltiazem].
    Vnitrni lekarstvi, 1985, Volume: 31, Issue:9

    Topics: Adenosine Diphosphate; Adult; Benzazepines; Diltiazem; Epinephrine; Female; Humans; Male; Platelet Aggregation

1985
Antithrombogenic effects of calcium channel blockers: synergism with prostacyclin and thromboxane synthase inhibitors.
    Thrombosis research, 1984, Jun-01, Volume: 34, Issue:5

    Topics: Adenosine Diphosphate; Benzofurans; Blood Platelets; Calcium Channel Blockers; Diltiazem; Drug Synergism; Epoprostenol; Humans; Nicotinic Acids; Nifedipine; Nimodipine; Oxidoreductases; Platelet Aggregation; Thrombin; Thromboxane A2; Thromboxane-A Synthase; Verapamil

1984
Inhibitory effects of diltiazem on platelet activation caused by ionophore A23187 plus ADP or epinephrine in subthreshold concentrations.
    The Journal of laboratory and clinical medicine, 1983, Volume: 102, Issue:3

    Topics: Adenosine Diphosphate; Adult; Benzazepines; Calcimycin; Calcium Chloride; Diltiazem; Epinephrine; Epoprostenol; Humans; Platelet Aggregation; Thromboxane A2; Thromboxane B2

1983
Effects of diltiazem, dipyridamole, and their combination on hemostasis.
    Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Adult; Benzazepines; Bleeding Time; Blood Pressure; Calcimycin; Diltiazem; Dipyridamole; Drug Therapy, Combination; Epinephrine; Heart Rate; Hemostasis; Humans; Male; Partial Thromboplastin Time; Platelet Aggregation; Prothrombin Time; Thromboxane B2

1984
Influence of verapamil and diltiazem on aggregatory responses in cat and rabbit platelet rich plasma.
    Prostaglandins, leukotrienes, and medicine, 1984, Volume: 16, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Benzazepines; Calcium Channel Blockers; Cats; Diltiazem; Female; In Vitro Techniques; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Rabbits; Verapamil

1984
Effects of antiplatelet agents on pulmonary metastases.
    Gan, 1984, Volume: 75, Issue:3

    Topics: Adenosine Diphosphate; Animals; Depression, Chemical; Diltiazem; Dipyridamole; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Platelet Aggregation; Thiophenes; Ticlopidine; Trapidil

1984
Prevention of reperfusion damage in working rat hearts by calcium antagonists and calmodulin antagonists.
    Journal of molecular and cellular cardiology, 1984, Volume: 16, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calmodulin; Cardiac Output; Coronary Circulation; Coronary Disease; Diltiazem; L-Lactate Dehydrogenase; Male; Myocardium; Nifedipine; Perfusion; Phosphocreatine; Rats; Rats, Inbred Strains; Sulfonamides; Verapamil

1984
Inhibition of platelet aggregation by diltiazem. Comparison with verapamil and nifedipine and inhibitory potencies of diltiazem metabolites.
    Circulation research, 1983, Volume: 52, Issue:2 Pt 2

    Topics: Adenosine Diphosphate; Animals; Benzazepines; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Nifedipine; Platelet Aggregation; Pyridines; Rabbits; Stereoisomerism; Verapamil

1983
Effect of Ca2+-antagonistic vasodilators, diltiazem, nifedipine, perhexiline and verapamil, on platelet aggregation in vitro.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:7

    Topics: Adenosine Diphosphate; Adolescent; Adult; Calcium; Collagen; Diltiazem; Epinephrine; Humans; In Vitro Techniques; Male; Nifedipine; Perhexiline; Platelet Aggregation; Vasodilator Agents; Verapamil

1981
Effects of diltiazem and verapamil on ADP-induced rabbit platelet shape change and aggregation.
    General pharmacology, 1995, Volume: 26, Issue:6

    Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Female; Male; Platelet Aggregation; Rabbits; Verapamil

1995
Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1996, Volume: 19, Issue:4

    Topics: Adenosine Diphosphate; Animals; Antioxidants; Calcium Channel Blockers; Cell Membrane; Dihydropyridines; Diltiazem; Felodipine; Fumarates; Heart; Iron; Lipid Peroxidation; Male; Myocardium; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Verapamil

1996
Antiplatelet mechanisms of TA-993 and its metabolite MB3 in ADP-induced platelet aggregation.
    European journal of pharmacology, 2000, Jul-07, Volume: 399, Issue:2-3

    Topics: Actins; Adenosine Diphosphate; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Fibrinogen; Fura-2; Humans; Male; Oligopeptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Binding

2000
Antiplatelet activity of semotiadil fumarate.
    Thrombosis research, 2002, May-15, Volume: 106, Issue:4-5

    Topics: Adenosine Diphosphate; Adult; Amlodipine; Calcium Channel Blockers; Case-Control Studies; Collagen; Diltiazem; Humans; Hypertension; Middle Aged; Nifedipine; Platelet Aggregation; Platelet Aggregation Inhibitors; Thiazoles

2002
HPLC assay with UV detection for determination of RBC purine nucleotide concentrations and application for biomarker study in vivo.
    Journal of pharmaceutical and biomedical analysis, 2008, Jun-09, Volume: 47, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biological Assay; Biomarkers; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diltiazem; Erythrocytes; Guanosine Triphosphate; Male; Physical Conditioning, Animal; Pilot Projects; Purine Nucleotides; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Reference Standards; Sensitivity and Specificity; Solid Phase Extraction; Species Specificity; Spectrophotometry, Ultraviolet

2008
[Protective effect of Tongxinluo Ultramicro-pulverization on experimental myocardial infarction of rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:15

    Topics: Adenosine Diphosphate; Animals; Aspirin; Diltiazem; Drugs, Chinese Herbal; Female; Male; Medicine, Chinese Traditional; Myocardial Infarction; Platelet Aggregation; Random Allocation; Rats; Rats, Sprague-Dawley; Tetrazolium Salts

2008
CNGA2 contributes to ATP-induced noncapacitative Ca2+ influx in vascular endothelial cells.
    Journal of vascular research, 2010, Volume: 47, Issue:2

    Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aminoquinolines; Aniline Compounds; Animals; Calcium Channel Blockers; Calcium Signaling; Cattle; Cells, Cultured; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Endothelial Cells; Enzyme Inhibitors; Imines; Male; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; RNA Interference; Thionucleotides; Time Factors; Transfection; Vasodilation; Xanthenes

2010