Page last updated: 2024-08-23

diltiazem and 1,4-dihydropyridine

diltiazem has been researched along with 1,4-dihydropyridine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19906 (26.09)18.7374
1990's12 (52.17)18.2507
2000's4 (17.39)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Christen, MO; Feron, O; Godfraind, T; Wibo, M1
Howlett, SE; Nicholl, PA1
Bick, IR; Felix, JP; Garcia, ML; Kaczorowski, GJ; King, VF; Shevell, JL; Slaughter, RS1
Glossmann, H; Knaus, HG; Romanin, C; Scheffauer, F; Schindler, HG1
Glossmann, H; Goll, A; Moosburger, K; Striessnig, J1
Atwal, KS; Bergey, JL; Hedberg, A; Moreland, S1
Glossmann, H; Zernig, G1
Cavero, I; Spedding, M1
Ferry, DR; Gadow, C; Glossmann, H; Goll, A1
Ferry, DR; Glossmann, H; Linn, T; Rombusch, M1
Birnbaumer, L; Kim, H; Lang, W; Pan, S; Perez-Reyes, E; Schneider, T; Wei, X1
Kugiyama, K; Ogawa, H; Okumura, K; Tsuchiya, T; Yasue, H1
Enyedi, P; Horváth, A; Rohács, T; Spät, A; Szabadkai, G1
Kuniyasu, A; Nakayama, H1
Grabner, M; Hering, S; Kraus, RL; Ostler, D; Striessnig, J1
Adachi-Akahane, S; Kanda, S; Nagao, T1
Gao, X; Gillman, MW; Goldman, L; Hertzmark, E; McLaughlin, TJ; Ross-Degnan, D; Soumerai, SB; Spiegelman, D1
Drew, T; Jinnah, HA; Kim, BS; Rothstein, JD; Visser, JE; Yitta, S1
Bidet, M; Martial, S; Martin, D; Melendez, E; Namorado, MD; Poujeol, C; Poujeol, P; Reyes, JL; Sanchez, E; Tauc, M; Valencia, L1
Handler, J1
Honda, A; Ishiguro, M; Russell, SR; Tranmer, BI; Wellman, GC; Wellman, TL1
Holstege, C; Winchester, DE1
Bergmann, I; Deters, M; Enden, G; Hentschel, H; Kutz, S; Liebetrau, G; Plenert, B; Prasa, D1

Reviews

2 review(s) available for diltiazem and 1,4-dihydropyridine

ArticleYear
"Calcium antagonists": a class of drugs with a bright future. Part II. Determination of basic pharmacological properties.
    Life sciences, 1984, Aug-06, Volume: 35, Issue:6

    Topics: Animals; Barium; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Electrophysiology; Heart Rate; Ion Channels; Lanthanum; Methods; Muscle, Smooth; Myocardial Contraction; Nifedipine; Potassium; Pyridines; Receptors, Adrenergic, alpha; Stereoisomerism; Verapamil

1984
Identification of binding sites for calcium channel antagonists.
    Japanese heart journal, 1996, Volume: 37, Issue:5

    Topics: Affinity Labels; Benzazepines; Binding Sites; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Drug Interactions; Humans; Muscle, Skeletal; Thiazepines; Verapamil

1996

Other Studies

21 other study(ies) available for diltiazem and 1,4-dihydropyridine

ArticleYear
Interaction of pinaverium (a quaternary ammonium compound) with 1,4-dihydropyridine binding sites in rat ileum smooth muscle.
    British journal of pharmacology, 1992, Volume: 105, Issue:2

    Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Dihydropyridines; Diltiazem; Ileum; In Vitro Techniques; Isradipine; Kinetics; Morpholines; Muscle, Smooth; Parasympatholytics; Rats; Receptors, Nicotinic; Saponins

1992
Density of 1,4-dihydropyridine receptors decreases in the hearts of aging hamsters.
    Journal of molecular and cellular cardiology, 1992, Volume: 24, Issue:8

    Topics: Aging; Allosteric Site; Animals; Calcium Channels; Cricetinae; Dihydropyridines; Diltiazem; In Vitro Techniques; Kinetics; Male; Myocardium; Nifedipine; Verapamil

1992
Bis(benzylisoquinoline) analogs of tetrandrine block L-type calcium channels: evidence for interaction at the diltiazem-binding site.
    Biochemistry, 1992, Dec-01, Volume: 31, Issue:47

    Topics: Alkaloids; Animals; Benzylisoquinolines; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Fluspirilene; Gallopamil; Isoquinolines; Isradipine; Kinetics; Molecular Conformation; Molecular Structure; Myocardium; Sarcolemma; Swine

1992
Heparin binds with high affinity to voltage-dependent L-type Ca2+ channels. Evidence for an agonistic action.
    The Journal of biological chemistry, 1990, Jul-05, Volume: 265, Issue:19

    Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Calcium Channels; Carps; Cell Membrane; Cerebral Cortex; Dihydropyridines; Diltiazem; Electric Conductivity; Guinea Pigs; Heparin; Isradipine; Molecular Sequence Data; Muscles; Myocardium; Nicotinic Antagonists; Oxadiazoles; Polyelectrolytes; Polymers; Rabbits; Receptors, Nicotinic; Stereoisomerism; Verapamil

1990
Purified calcium channels have three allosterically coupled drug receptors.
    FEBS letters, 1986, Mar-03, Volume: 197, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Amines; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Guinea Pigs; Ion Channels; Isradipine; Muscles; Nifedipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil

1986
Synthesis and biological activity of novel calcium channel blockers: 2,5-dihydro-4-methyl-2-phenyl-1,5-benzothiazepine-3-carboxylic acid esters and 2,5-dihydro-4-methyl-2-phenyl-1,5-benzodiazepine-3-carboxylic acid esters.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:4

    Topics: Action Potentials; Animals; Aorta; Benzodiazepines; Calcium Channel Blockers; Calcium Channels; Carboxylic Acids; Chemical Phenomena; Chemistry; Dihydropyridines; Diltiazem; Guinea Pigs; Ion Channels; Pyridines; Rabbits; Receptors, Nicotinic; Structure-Activity Relationship; Thiazepines

1987
A novel 1,4-dihydropyridine-binding site on mitochondrial membranes from guinea-pig heart, liver and kidney.
    The Biochemical journal, 1988, Jul-01, Volume: 253, Issue:1

    Topics: Animals; Binding Sites; Centrifugation, Density Gradient; Dihydropyridines; Diltiazem; Guinea Pigs; Intracellular Membranes; Kidney; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Nitrendipine; Osmolar Concentration; Subcellular Fractions; Verapamil

1988
(-)-3H-desmethoxyverapamil labelling of putative calcium channels in brain: autoradiographic distribution and allosteric coupling to 1,4-dihydropyridine and diltiazem binding sites.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 327, Issue:2

    Topics: Animals; Autoradiography; Benzazepines; Binding Sites; Brain; Dihydropyridines; Diltiazem; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Kinetics; Membranes; Pyridines; Stereoisomerism; Verapamil

1984
Temperature-dependent regulation of d-cis-[3H]diltiazem binding to Ca2+ channels by 1,4-dihydropyridine channel agonists and antagonists.
    FEBS letters, 1983, Aug-22, Volume: 160, Issue:1-2

    Topics: Animals; Benzazepines; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Guinea Pigs; Ion Channels; Kinetics; Microsomes; Muscles; Pyridines; Stereoisomerism; Structure-Activity Relationship; Temperature

1983
Molecular determinants of cardiac Ca2+ channel pharmacology. Subunit requirement for the high affinity and allosteric regulation of dihydropyridine binding.
    The Journal of biological chemistry, 1995, Nov-10, Volume: 270, Issue:45

    Topics: Allosteric Regulation; Animals; Calcium Channels; Cell Line; Dihydropyridines; Diltiazem; DNA, Complementary; Female; Kinetics; Ligands; Molecular Structure; Muscle, Skeletal; Myocardium; Nisoldipine; Oocytes; Protein Conformation; Rabbits; Transfection; Xenopus

1995
Heart period variability in patients with variant angina.
    The American journal of cardiology, 1996, May-01, Volume: 77, Issue:11

    Topics: Aged; Angina Pectoris, Variant; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Electrocardiography, Ambulatory; Female; Heart Conduction System; Heart Rate; Humans; Male; Middle Aged; Nifedipine; Nisoldipine; Sympathetic Nervous System

1996
The role of voltage-dependent calcium channels in angiotensin-stimulated glomerulosa cells.
    Endocrine research, 1996, Volume: 22, Issue:4

    Topics: Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Radioisotopes; Cytoplasm; Dihydropyridines; Diltiazem; Electrophysiology; Inositol 1,4,5-Trisphosphate Receptors; Manganese; Membrane Potentials; Potassium; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Zona Glomerulosa

1996
Molecular mechanism of diltiazem interaction with L-type Ca2+ channels.
    The Journal of biological chemistry, 1998, Oct-16, Volume: 273, Issue:42

    Topics: Alanine; Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Dihydropyridines; Diltiazem; DNA Mutational Analysis; Electric Conductivity; Electrophysiology; Ion Channel Gating; Isradipine; Muscle, Skeletal; Mutagenesis

1998
Functional interaction between benzothiazepine- and dihydropyridine binding sites of cardiac L-type Ca2+ channels.
    European journal of pharmacology, 1998, Oct-09, Volume: 358, Issue:3

    Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cell Line; Dihydropyridines; Diltiazem; Membrane Potentials; Myocardium; Nitrendipine; Patch-Clamp Techniques; Temperature; Thiazepines; Time Factors

1998
Effects of long-acting versus short-acting calcium channel blockers among older survivors of acute myocardial infarction.
    Journal of the American Geriatrics Society, 1999, Volume: 47, Issue:5

    Topics: Aged; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Female; Humans; Male; Myocardial Infarction; Nicardipine; Nifedipine; Proportional Hazards Models; Retrospective Studies; Risk; Survival Analysis; Survivors; Verapamil

1999
Calcium channel activation and self-biting in mice.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Dec-21, Volume: 96, Issue:26

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Animals; Behavior, Animal; Bites and Stings; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diltiazem; Ion Channel Gating; Mice; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Pyrroles; Self-Injurious Behavior

1999
Nifedipine-activated Ca(2+) permeability in newborn rat cortical collecting duct cells in primary culture.
    American journal of physiology. Cell physiology, 2001, Volume: 280, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Biological Transport; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cells, Cultured; Cytosol; Dihydropyridines; Diltiazem; Egtazic Acid; Gadolinium; Hydrogen Peroxide; Isradipine; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Lanthanum; Nifedipine; Protamines; Rats; Rats, Sprague-Dawley; Thapsigargin; Verapamil

2001
Case studies in hypertension. Dihydropyridine/nondihydropyridine calcium channel blocker combination therapy.
    Journal of clinical hypertension (Greenwich, Conn.), 2005, Volume: 7, Issue:1

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Drug Therapy, Combination; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Nifedipine; Verapamil

2005
Emergence of a R-type Ca2+ channel (CaV 2.3) contributes to cerebral artery constriction after subarachnoid hemorrhage.
    Circulation research, 2005, Mar-04, Volume: 96, Issue:4

    Topics: Animals; Blood; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, R-Type; Cerebral Arteries; Cisterna Magna; Dihydropyridines; Diltiazem; Disease Models, Animal; Drug Resistance; Injections; Ion Transport; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Rabbits; Spider Venoms; Subarachnoid Hemorrhage; Vasoconstriction; Vasospasm, Intracranial

2005
Inclusion of patients who overdose with dihydropyridine calcium channel blockers would potentially increase clinical utility of hyperglycemia.
    Critical care medicine, 2008, Volume: 36, Issue:2

    Topics: Calcium Channel Blockers; Dihydropyridines; Diltiazem; Drug Overdose; Heart Rate; Humans; Hyperglycemia; Patient Selection; Verapamil

2008
Calcium channel antagonist exposures reported to the Poisons Information Center Erfurt.
    European journal of internal medicine, 2011, Volume: 22, Issue:6

    Topics: Adolescent; Adult; Age Distribution; Aged; Calcium Channel Blockers; Child; Dihydropyridines; Diltiazem; Drug Overdose; Drug Synergism; Germany; Humans; Infant; Middle Aged; Poison Control Centers; Retrospective Studies; Verapamil; Young Adult

2011