dilazep has been researched along with thioinosine in 59 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (35.59) | 18.7374 |
| 1990's | 25 (42.37) | 18.2507 |
| 2000's | 12 (20.34) | 29.6817 |
| 2010's | 1 (1.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cass, CE; Janowska-Wieczorek, A; King, KM; Montaño, JT | 1 |
| Doherty, AJ; Griffith, DA; Jarvis, SM | 1 |
| Dagnino, L; Paterson, AR | 1 |
| Gero, AM; Wood, AM | 1 |
| Van Belle, H; Ver Donck, K; Wynants, J | 1 |
| Baer, HP; Moorji, A; Serignese, V; Van Belle, H | 1 |
| al-Jaser, MH; Baer, HP; Ogbunude, PO | 1 |
| Baer, HP; el-Soofi, A; Haq, A; Paterson, AR; Serignese, V | 1 |
| IJzerman, AP; Voorschuur, AH | 1 |
| Averett, DR; Prus, KL; Zimmerman, TP | 1 |
| Baer, HP; Ogbunude, PO | 2 |
| Baer, HP; Moorji, A | 1 |
| Barrett, J; Beechey, RB; Harris, DI; Linstead, D | 1 |
| Christopherson, RI; Gero, AM; O'Sullivan, WJ; Scott, HV | 1 |
| Gati, WP; Paterson, AR | 1 |
| Gero, AM | 1 |
| Geiger, JD; Johnston, ME | 1 |
| Plagemann, PG; Woffendin, C; Wohlhueter, RM | 1 |
| Jarvis, SM; Lee, CW | 1 |
| Agarwal, KC; Dawicki, DD; Parks, RE | 2 |
| Plagemann, PG; Woffendin, C | 1 |
| Geiger, JD; Johnston, ME; Yago, V | 1 |
| Plagemann, PG | 1 |
| Cha, S; el Kouni, MH | 1 |
| Cha, S; el Kouni, MH; Messier, NJ | 1 |
| Kraupp, M; Plagemann, PG | 1 |
| Shi, MM; Young, JD | 1 |
| Sanderson, G; Scholfield, CN | 1 |
| Clanachan, AS; Williams, EF | 1 |
| Jarvis, SM; Young, JD | 1 |
| Cass, CE; Koren, R; Paterson, AR | 1 |
| Delander, GE; Keil, GJ | 1 |
| Gero, AM; Upston, JM | 1 |
| Sasvari-Szekely, M; Solymossy, M; Staub, M; Szikla, K | 1 |
| Foga, IO; Geiger, JD; Gu, JG; Parkinson, FE | 1 |
| Lee, CW | 1 |
| Griffith, DA; Jarvis, SM | 1 |
| Cass, CE; Fang, X; Mowles, DA; Parkinson, FE; Young, JD | 1 |
| Geiger, JD; Gu, JG; Nath, A | 1 |
| Geiger, JD; Mukherjee, K; Parkinson, FE | 1 |
| Guo, X; Kulkarni, JS; Palmer, KC; Przywara, DA; Wakade, AR; Wakade, TD | 1 |
| Baer, HP; Das, P; Das, SR; Moorji, A | 1 |
| Baldwin, SA; Cass, CE; Griffiths, M; Muzyka, WR; Ng, AM; Yao, SY; Young, JD | 1 |
| Baldwin, SA; Cass, CE; Hogue, DL; Mani, RS; Sundaram, M; Vickers, MF; Young, JD | 1 |
| Camarasa, J; Camins, A; Escubedo, E; Jiménez, A; Lladó, S; Pallàs, M; Pubill, D | 1 |
| Baldwin, SA; Cass, CE; Hyde, RJ; McConkey, GA; McRobert, L; Parker, MD; Yao, SY; Young, JD | 1 |
| Baldwin, SA; Carpenter, P; Cass, CE; Chen, XZ; Graham, K; Hyde, RJ; Karpinski, E; Loewen, SK; Mowles, DA; Ng, AM; Ritzel, MW; Ritzel, RG; Smith, KM; Yao, SY; Young, JD | 1 |
| Baldwin, SA; Cass, CE; Ng, AM; Vickers, MF; Visser, F; Young, JD | 1 |
| Bilan, PJ; Coe, IR; Shuralyova, I; Sweeney, G; Tajmir, P | 1 |
| Endres, CJ; Sengupta, DJ; Unadkat, JD | 1 |
| SenGupta, DJ; Unadkat, JD | 1 |
| Archer, RG; Hammond, JR; McConnell, K; Stolk, M | 1 |
| Archer, RG; Hammond, JR; Pitelka, V | 1 |
| Baldwin, SA; Cass, CE; Damaraju, V; Peng, Y; Robins, MJ; Sun, L; Tackaberry, T; Visser, F; Young, JD | 1 |
| Bone, DB; Hammond, JR | 1 |
| Baldwin, SA; Cass, CE; Damaraju, V; Paproski, RJ; Tackaberry, T; Visser, F; Young, JD; Zhang, J | 1 |
| Lee, SY; Wright, NJ | 1 |
2 review(s) available for dilazep and thioinosine
| Article | Year |
|---|---|
Nucleoside and nucleobase transport in animal cells.
Topics: Adenine; Algorithms; Animals; Biological Transport; Dilazep; Dipyridamole; Hypoxanthine; Hypoxanthines; Kinetics; Lidoflazine; Monosaccharide Transport Proteins; Nucleosides; Temperature; Thioinosine; Thionucleosides | 1988 |
Nucleoside transport in animal cells.
Topics: Animals; Biological Transport, Active; Diazepam; Dilazep; Dipyridamole; Erythrocyte Membrane; Erythrocytes; Humans; Inosine; Kinetics; Membrane Proteins; Models, Molecular; Nucleosides; Papaverine; Species Specificity; Thioinosine; Uridine | 1983 |
57 other study(ies) available for dilazep and thioinosine
| Article | Year |
|---|---|
A comparison of the abilities of nitrobenzylthioinosine, dilazep, and dipyridamole to protect human hematopoietic cells from 7-deazaadenosine (tubercidin).
Topics: Adenosine; Colony-Forming Units Assay; Dilazep; Dipyridamole; Hematopoietic Stem Cells; Humans; Leukemia, Promyelocytic, Acute; Thioinosine; Tubercidin; Tumor Cells, Cultured | 1992 |
Nucleoside transport in cultured LLC-PK1 epithelia.
Topics: Affinity Labels; Animals; Biological Transport; Cell Line; Dilazep; Epithelium; Kidney Cortex; Kidney Medulla; Kinetics; Microvilli; Nucleosides; Swine; Thioinosine; Uridine | 1992 |
Sodium-dependent and equilibrative nucleoside transport systems in L1210 mouse leukemia cells: effect of inhibitors of equilibrative systems on the content and retention of nucleosides.
Topics: Animals; Biological Transport; Dilazep; Dipyridamole; Formycins; Leukemia L1210; Mice; Nucleosides; Sodium; Thioinosine; Vidarabine; Vidarabine Phosphate | 1990 |
New nucleoside transport pathways induced in the host erythrocyte membrane of malaria and Babesia infected cells.
Topics: Adenosine; Animals; Babesia bovis; Babesiosis; Biological Transport; Cattle; Cattle Diseases; Dilazep; Drug Therapy, Combination; Erythrocyte Membrane; Erythrocytes; Malaria; Malaria, Falciparum; Mice; Plasmodium falciparum; Pyrimidine Nucleosides; Thioinosine; Thionucleotides; Tubercidin | 1991 |
Comparison of the existing nucleoside transport inhibitors: in vitro and in vivo data.
Topics: Animals; Biological Transport; Dilazep; Dipyridamole; Epinephrine; Erythrocytes; Humans; In Vitro Techniques; Nucleosides; Phosphates; Piperazines; Rabbits; Thioinosine | 1991 |
In vivo effectiveness of several nucleoside transport inhibitors in mice and hamsters.
Topics: Adenosine; Administration, Oral; Animals; Biological Transport; Cardiovascular Agents; Cricetinae; Dilazep; Injections, Intraperitoneal; Mesocricetus; Mice; Mice, Inbred BALB C; Piperazines; Species Specificity; Thioinosine | 1991 |
Leishmania donovani: characteristics of adenosine and inosine transporters in promastigotes of two different strains.
Topics: Adenosine; Animals; Biological Transport; Diffusion; Dilazep; Inosine; Kinetics; Leishmania donovani; Nucleosides; Thioinosine; Thymidine; Uridine | 1991 |
Potencies of mioflazine and its derivatives as inhibitors of adenosine transport in isolated erythrocytes from different species.
Topics: Adenosine; Animals; Cricetinae; Dilazep; Dimethyl Sulfoxide; Erythrocytes; Humans; In Vitro Techniques; Male; Mesocricetus; Mice; Mice, Inbred BALB C; Papio; Piperazines; Rabbits; Species Specificity; Thioinosine | 1990 |
The relationship between ionization and affinity of nucleoside transport inhibitors.
Topics: Animals; Binding, Competitive; Cattle; Dilazep; Hexobendine; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Membranes; Nucleosides; Piperazines; Spectrophotometry, Ultraviolet; Thermodynamics; Thioinosine | 1990 |
Transport and metabolism of 9-beta-D-arabinofuranosylguanine in a human T-lymphoblastoid cell line: nitrobenzylthioinosine-sensitive and -insensitive influx.
Topics: Arabinonucleosides; Biological Transport; Cell Division; Cell Line; Dilazep; Dipyridamole; Erythrocytes; Humans; Inosine; Kinetics; Leukemia-Lymphoma, Adult T-Cell; Purines; Ribonucleosides; Thioinosine; Tubercidin; Tumor Cells, Cultured | 1990 |
Competition of nucleoside transport inhibitors with binding of 6-[(4-nitrobenzyl)-mercapto]purine ribonucleoside to intact erythrocytes and ghost membranes from different species.
Topics: Adenosine; Animals; Binding, Competitive; Carrier Proteins; Cricetinae; Dilazep; Erythrocyte Membrane; Erythrocytes; Hot Temperature; Humans; Hydrogen-Ion Concentration; Inosine; Membrane Proteins; Mice; Nucleoside Transport Proteins; Piperazines; Rats; Thioinosine | 1990 |
Sodium-dependent and inhibitor-insensitive uptake of adenosine by mouse peritoneal exudate cells.
Topics: Adenosine; Animals; Biological Transport, Active; Cell Adhesion; Dilazep; Erythrocytes; In Vitro Techniques; Macrophages; Mice; Mice, Inbred BALB C; Peritoneal Cavity; Sodium; Thioinosine; Time Factors | 1990 |
Nucleoside uptake by Trichomonas vaginalis.
Topics: Adenosine; Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Cytidine; Dilazep; DNA; Guanosine; Inosine; Kinetics; Nucleosides; RNA; Thioinosine; Thionucleosides; Thymidine; Trichomonas vaginalis; Uridine | 1988 |
Antimalarial action of nitrobenzylthioinosine in combination with purine nucleoside antimetabolites.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Biological Transport; Cell Membrane Permeability; Cells, Cultured; Chromatography, High Pressure Liquid; Dilazep; Dipyridamole; Erythrocytes; Guanosine; Humans; Inosine; Molecular Structure; Nucleosides; Plasmodium falciparum; Thioinosine; Thionucleosides; Tubercidin | 1989 |
Interaction of [3H]dilazep at nucleoside transporter-associated binding sites on S49 mouse lymphoma cells.
Topics: Animals; Azepines; Binding Sites; Carrier Proteins; Dilazep; Hydrogen-Ion Concentration; Inosine; Kinetics; Lymphoma; Membrane Proteins; Mice; Nucleoside Transport Proteins; Physostigmine; Thioinosine; Tumor Cells, Cultured | 1989 |
Induction of nucleoside transport sites into the host cell membrane of Babesia bovis infected erythrocytes.
Topics: Adenosine; Animals; Babesia; Binding Sites; Biological Transport; Cattle; Dilazep; Dipyridamole; Erythrocyte Membrane; Erythrocytes; Guanosine; Humans; Kinetics; Phloretin; Phlorhizin; Thioinosine; Thionucleosides; Verapamil | 1989 |
Binding of [G-3H]6-(4-nitrobenzylmercapto)purine ribonucleoside to isolated membranes. Inhibitory effect of mioflazine and its derivatives.
Topics: Animals; Binding Sites; Cardiovascular Agents; Cell Membrane; Cricetinae; Dilazep; In Vitro Techniques; Inosine; Liver; Lung; Male; Mesocricetus; Piperazines; Thioinosine | 1989 |
Sodium-dependent uptake of nucleosides by dissociated brain cells from the rat.
Topics: Adenosine; Animals; Brain; Dilazep; Dipyridamole; Kinetics; Male; Nucleosides; Ouabain; Rats; Rats, Inbred Strains; Sodium; Thioinosine; Uridine | 1989 |
Nucleoside transport in rat cerebral-cortical synaptosomes. Evidence for two types of nucleoside transporters.
Topics: Animals; Biological Transport; Cerebral Cortex; Dilazep; Dipyridamole; Male; Nucleosides; Rats; Rats, Inbred Strains; Synaptosomes; Thioinosine; Uridine | 1988 |
Adenosine metabolism in human whole blood. Effects of nucleoside transport inhibitors and phosphate concentration.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Biological Transport; Dilazep; Dipyridamole; Humans; Phosphates; Thioinosine | 1988 |
Species differences in sensitivity of nucleoside transport in erythrocytes and cultured cells to inhibition by nitrobenzylthioinosine, dipyridamole, dilazep and lidoflazine.
Topics: Animals; Azepines; Biological Transport; Carrier Proteins; Cells, Cultured; Dilazep; Dipyridamole; Erythrocytes; Humans; Inosine; Lidoflazine; Membrane Proteins; Nucleoside Transport Proteins; Piperazines; Species Specificity; Thioinosine; Uridine | 1988 |
Pharmacological characterization of rapidly accumulated adenosine by dissociated brain cells from adult rat.
Topics: Adenosine; Adenosine Monophosphate; Animals; Binding, Competitive; Brain; Dilazep; Dipyridamole; Inosine; Kinetics; Male; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Thioinosine; Uridine | 1988 |
Transport and metabolism of adenosine in human erythrocytes: effect of transport inhibitors and regulation by phosphate.
Topics: Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Biological Transport; Coformycin; Dilazep; Dipyridamole; Erythrocytes; Humans; Pentostatin; Phosphates; Phosphorylation; Thioinosine | 1986 |
Metabolism of adenosine analogues by Schistosoma mansoni and the effect of nucleoside transport inhibitors.
Topics: Adenosine; Animals; Biological Transport; Dilazep; Dipyridamole; Kinetics; Nucleosides; Schistosoma mansoni; Structure-Activity Relationship; Thioinosine; Thionucleotides; Uracil | 1987 |
Treatment of schistosomiasis by purine nucleoside analogues in combination with nucleoside transport inhibitors.
Topics: Adenosine; Animals; Biological Transport; Dilazep; Dipyridamole; Drug Therapy, Combination; Female; Mice; Purine Nucleosides; Ribonucleosides; Schistosoma mansoni; Schistosomiasis; Thioinosine; Thionucleotides; Toyocamycin; Tubercidin; Uracil | 1987 |
Inhibition of nucleoside and nucleobase transport and nitrobenzylthioinosine binding by dilazep and hexobendine.
Topics: Animals; Azepines; Benzoates; Biological Transport; Carbon Radioisotopes; Cell Line; Cricetinae; Cricetulus; Dilazep; Dipyridamole; Erythrocytes; Hexobendine; Humans; Hypoxanthine; Hypoxanthines; Inosine; Mice; Nucleosides; Rats; Thioinosine; Uridine | 1986 |
[3H]dipyridamole binding to nucleoside transporters from guinea-pig and rat lung.
Topics: Animals; Carrier Proteins; Cell Membrane; Dilazep; Dipyridamole; Guinea Pigs; Lidoflazine; Lung; Male; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Rats; Rats, Inbred Strains; Thioinosine | 1986 |
Effects of adenosine uptake blockers and adenosine on evoked potentials of guinea-pig olfactory cortex.
Topics: Adenosine; Adenosine Deaminase; Animals; Diazepam; Dilazep; Dipyridamole; Evoked Potentials; Flurazepam; Guanosine; Guinea Pigs; Hexobendine; In Vitro Techniques; Limbic System; Olfactory Pathways; Thioinosine; Thionucleosides | 1986 |
Role of adenosine uptake and metabolism by blood cells in the antiplatelet actions of dipyridamole, dilazep and nitrobenzylthioinosine.
Topics: Adenosine; Azepines; Blood Platelets; Dilazep; Dipyridamole; Erythrocytes; Humans; In Vitro Techniques; Inosine; Mopidamol; Platelet Aggregation; Thioinosine | 1985 |
Saturable, high affinity binding of the nucleoside transport inhibitor, nitrobenzylthioinosine, to guinea pig cardiac membranes.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding Sites; Biological Transport; Dilazep; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Inosine; Membranes; Myocardium; Thioinosine | 1983 |
The kinetics of dissociation of the inhibitor of nucleoside transport, nitrobenzylthioinosine, from the high-affinity binding sites of cultured hamster cells.
Topics: Animals; Binding Sites; Biological Transport; Cell Division; Cell Line; Cell Membrane; Cell Transformation, Viral; Clone Cells; Cricetinae; Dilazep; Fibroblasts; Inosine; Kinetics; Mesocricetus; Nucleosides; Thioinosine; Uridine | 1983 |
Time-dependent antinociceptive interactions between opioids and nucleoside transport inhibitors.
Topics: Adenosine; Analgesics; Animals; Biological Transport; Dilazep; Dipyridamole; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Narcotics; Nucleosides; Receptors, Opioid; Thioinosine; Time Factors | 1995 |
Altered purine nucleoside transport as a target for malaria chemotherapy.
Topics: Adenosine; Affinity Labels; Alkaloids; Animals; Antimalarials; Benzodioxoles; Benzoquinones; Biological Transport; Ciona intestinalis; Crithidia; Dilazep; Erythrocytes; Furosemide; HeLa Cells; Humans; Malaria, Falciparum; Phlorhizin; Piperidines; Plasmodium falciparum; Polyunsaturated Alkamides; Stereoisomerism; Thioinosine; Trichomonas vaginalis | 1994 |
Nucleoside transport and metabolism in lymphocytes, polymorphonuclear cells and cerebral synaptosomes.
Topics: Adenosine; Animals; Biological Transport; Cerebral Cortex; Child; Deoxycytidine; Dilazep; Dipyridamole; DNA; Humans; Kinetics; Lymphocytes; Neutrophils; Nucleosides; Palatine Tonsil; Papaverine; Rats; Synaptosomes; Thioinosine; Thymidine; Uridine | 1994 |
Involvement of bidirectional adenosine transporters in the release of L-[3H]adenosine from rat brain synaptosomal preparations.
Topics: Adenosine; Animals; Biological Transport; Brain; Carrier Proteins; Dilazep; Dipyridamole; Kinetics; Male; Membrane Proteins; Nucleoside Transport Proteins; Potassium Chloride; Rats; Rats, Sprague-Dawley; Synaptosomes; Thioinosine; Tritium | 1995 |
Decrease in equilibrative uridine transport during monocytic differentiation of HL-60 leukaemia: involvement of protein kinase C.
Topics: Affinity Labels; Alkaloids; Binding Sites; Biological Transport; Cell Differentiation; Dilazep; Dipyridamole; Humans; Kinetics; Leukemia; Monocytes; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thioinosine; Thymidine; Tumor Cells, Cultured; Uracil; Uridine | 1994 |
High affinity sodium-dependent nucleobase transport in cultured renal epithelial cells (LLC-PK1).
Topics: Animals; Biological Transport; Cations, Monovalent; Cell Line; Dilazep; Dipyridamole; Epithelium; Hypoxanthine; Hypoxanthines; Kidney; Kinetics; Nucleosides; Purines; Pyrimidines; Sodium; Thioinosine; Tritium | 1993 |
Functional characterization of a recombinant sodium-dependent nucleoside transporter with selectivity for pyrimidine nucleosides (cNT1rat) by transient expression in cultured mammalian cells.
Topics: Adenosine; Amino Acid Sequence; Animals; Base Sequence; Biological Transport; Carrier Proteins; Cells, Cultured; Dilazep; Dipyridamole; Genes, myc; Guanosine; Haplorhini; Intestines; Kidney; Membrane Transport Proteins; Molecular Sequence Data; Nucleosides; Pyrimidine Nucleosides; Rats; Recombinant Proteins; Thioinosine; Transfection; Uridine | 1996 |
Characterization of inhibitor-sensitive and -resistant adenosine transporters in cultured human fetal astrocytes.
Topics: Adenine; Adenosine; Affinity Labels; Astrocytes; Biological Transport; Carrier Proteins; Cells, Cultured; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fetus; Humans; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Thioinosine; Tritium; Tubercidin; Vasodilator Agents | 1996 |
[3H]adenosine transport in DDT1 MF-2 smooth muscle cells: inhibition by metabolites of propentofylline.
Topics: Adenosine; Animals; Binding Sites; Biological Transport; Cricetinae; Dilazep; Dipyridamole; Genital Neoplasms, Male; Kinetics; Leiomyosarcoma; Leukemia L1210; Male; Mesocricetus; Muscle, Smooth; Rats; Thioinosine; Tumor Cells, Cultured; Vas Deferens; Xanthines | 1996 |
2'-deoxyadenosine induces apoptosis in rat chromaffin cells.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Apoptosis; Chromaffin Cells; Deoxyadenosines; Dilazep; Enzyme Inhibitors; Epinephrine; Mutagens; Norepinephrine; Phosphorylation; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Thioinosine; Tubercidin; Vasodilator Agents | 1996 |
Characterization of nucleoside uptake and transport in Entamoeba histolytica.
Topics: Animals; Biological Transport; Dilazep; Entamoeba histolytica; Nucleosides; Purine Nucleosides; Pyrimidine Nucleosides; Thioinosine | 1997 |
Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Carrier Proteins; Cloning, Molecular; Dilazep; Dipyridamole; Electrophoresis, Polyacrylamide Gel; Equilibrative Nucleoside Transport Proteins; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Humans; Membrane Proteins; Molecular Sequence Data; Nuclear Proteins; Nucleoside Transport Proteins; Peptide Mapping; Protein Structure, Secondary; Rats; Sequence Alignment; Thioinosine; Vasodilator Agents; Xenopus | 1997 |
Functional production and reconstitution of the human equilibrative nucleoside transporter (hENT1) in Saccharomyces cerevisiae. Interaction of inhibitors of nucleoside transport with recombinant hENT1 and a glycosylation-defective derivative (hENT1/N48Q).
Topics: Base Sequence; Biological Transport; Carrier Proteins; Dilazep; Dipyridamole; DNA Primers; Equilibrative Nucleoside Transporter 1; Genetic Complementation Test; Glycosylation; Humans; Kinetics; Membrane Proteins; Proteolipids; Recombinant Proteins; RNA, Messenger; Saccharomyces cerevisiae; Thioinosine; Thymidine | 1999 |
Further characterization of an adenosine transport system in the mitochondrial fraction of rat testis.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Benzodiazepinones; Biological Transport; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Guanosine; Hexobendine; Hydrogen-Ion Concentration; Inosine; Isoquinolines; Kinetics; Male; Mitochondria; Osmolar Concentration; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley; Sodium; Subcellular Fractions; Temperature; Testis; Thioinosine; Thionucleosides; Time Factors; Tritium; Uridine | 2000 |
Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy.
Topics: Adenine; Amino Acid Sequence; Animals; Antimalarials; Biological Transport; Blotting, Southern; Carrier Proteins; Cations; Cell Membrane; Cloning, Molecular; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Nucleobase, Nucleoside, Nucleotide, and Nucleic Acid Transport Proteins; Nucleosides; Phylogeny; Piperazines; Plasmodium falciparum; Platelet Aggregation Inhibitors; Protein Structure, Secondary; Protozoan Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Thioinosine; Time Factors; Uridine; Vasodilator Agents; Xenopus | 2000 |
Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).
Topics: Amino Acid Sequence; Animals; Biological Transport; Carrier Proteins; Cell Differentiation; Dilazep; Dipyridamole; Electric Conductivity; Evolution, Molecular; HL-60 Cells; Humans; Membrane Transport Proteins; Mice; Models, Molecular; Molecular Sequence Data; Purine Nucleosides; Pyrimidine Nucleosides; Recombinant Proteins; Sequence Homology, Amino Acid; Sodium; Substrate Specificity; Symporters; Thioinosine; Uridine | 2001 |
Mutation of residue 33 of human equilibrative nucleoside transporters 1 and 2 alters sensitivity to inhibition of transport by dilazep and dipyridamole.
Topics: Amino Acid Sequence; Animals; Biological Transport; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Humans; Membrane Transport Proteins; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Recombinant Proteins; Structure-Activity Relationship; Thioinosine; Uridine; Xenopus laevis | 2002 |
Inhibition of glucose uptake in murine cardiomyocyte cell line HL-1 by cardioprotective drugs dilazep and dipyridamole.
Topics: Adenosine; Animals; Biological Transport; Cardiotonic Agents; Cell Line; Deoxyglucose; Dilazep; Dipyridamole; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Kinetics; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Myocytes, Cardiac; Thioinosine | 2004 |
Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1.
Topics: Adenosine; Amino Acid Substitution; Biological Transport; Dilazep; Dipyridamole; Drug Resistance; Equilibrative Nucleoside Transporter 1; Guanosine; Humans; Inhibitory Concentration 50; Inosine; Leucine; Mutagenesis; Mutation, Missense; Point Mutation; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Thioinosine | 2004 |
Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep.
Topics: Biological Transport; Dilazep; Dipyridamole; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Glycine; Humans; Nucleosides; Thioinosine; Vasodilator Agents | 2004 |
Pharmacological analysis and molecular cloning of the canine equilibrative nucleoside transporter 1.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Carrier Proteins; Cell Line; Cloning, Molecular; Dilazep; Dipyridamole; DNA, Complementary; Dogs; Dose-Response Relationship, Drug; Equilibrative Nucleoside Transporter 1; Formycins; Kinetics; Molecular Sequence Data; Piperazines; Protein Binding; Protein Conformation; Radioligand Assay; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Structure-Activity Relationship; Thioinosine; Tritium | 2004 |
Nucleoside transporter subtype expression and function in rat skeletal muscle microvascular endothelial cells.
Topics: Animals; Capillaries; Cell Separation; Cells, Cultured; Dilazep; Dipyridamole; DNA Primers; Endothelial Cells; Formycins; Muscle, Skeletal; Nucleoside Transport Proteins; Piperazines; Radioligand Assay; Rats; Reverse Transcriptase Polymerase Chain Reaction; Thioinosine; Vasodilator Agents | 2004 |
Residues 334 and 338 in transmembrane segment 8 of human equilibrative nucleoside transporter 1 are important determinants of inhibitor sensitivity, protein folding, and catalytic turnover.
Topics: Adenosine; Amino Acid Sequence; Biological Transport; Dilazep; Equilibrative Nucleoside Transporter 1; Genetic Complementation Test; Heterocyclic Compounds; Humans; Membrane Proteins; Molecular Sequence Data; Mutagenesis; Mutation; Nucleosides; Protein Conformation; Protein Folding; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Thioinosine | 2007 |
Nucleoside and nucleobase transporters of primary human cardiac microvascular endothelial cells: characterization of a novel nucleobase transporter.
Topics: 2-Chloroadenosine; Animals; Cell Culture Techniques; Cell Line; Cells, Cultured; Child, Preschool; Coronary Vessels; Dilazep; Dipyridamole; Dogs; Endothelial Cells; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Female; Humans; Hypoxanthine; Kinetics; Microcirculation; Nucleobase Transport Proteins; Piperazines; Protein Binding; Purines; Rats; Swine; Thioinosine; Transfection; Tritium | 2007 |
Mutation of Trp29 of human equilibrative nucleoside transporter 1 alters affinity for coronary vasodilator drugs and nucleoside selectivity.
Topics: Adenosine; Biological Transport; Dilazep; Dipyridamole; Enzyme Activation; Equilibrative Nucleoside Transporter 1; Humans; Kinetics; Models, Biological; Mutation; Nucleosides; Piperazines; Protein Binding; Thioinosine; Tryptophan; Vasodilator Agents | 2008 |
Structures of human ENT1 in complex with adenosine reuptake inhibitors.
Topics: Adenosine; Crystallography, X-Ray; Dilazep; Equilibrative Nucleoside Transporter 1; Humans; Models, Molecular; Protein Conformation; Thioinosine | 2019 |