dihydroxyphenylalanine and probenecid

dihydroxyphenylalanine has been researched along with probenecid in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199041 (97.62)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (2.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellman, K; Knegtel, RM; Settimo, L1
Borison, RL; Giardina, WJ; Mosnaim, AD; Pedemonte, WA; Sabelli, HC; Vazquez, AJ1
Ahtee, L; Carlsson, A1
Dehner, EJ; Martin, ET; Schwartz, JB1
Korf, J; Praag, HM; Schut, T1
MacMillan, V1
Trulson, ME; Ulissey, MJ1
Van Woert, MH; Weintraub, MI1
Korf, J; Lakke, JP; van Praag, HM1
Carlsson, A; Davis, JN1
Weiner, N1
Gordon, EK; Oliver, J1
Chase, TN; Gordon, EK; Ng, LK1
Goodwin, FK; Post, RM1
Garelis, E; Lal, S; Sourkes, TL; Young, SN1
Chase, TN3
Lycke, E; Roos, BE1
Chase, TN; Cramer, H; Ng, LK1
Laaksonen, H; Riekkinen, P; Rinne, UK; Sonninen, V1
Bowers, MB; Extein, I; Roth, RH1
Korf, J; Lakke, JP; Schut, T; Van Praag, HM1
Barbeau, A1
Goodwin, FK; Sack, RL1
Arnold, EL; Back, KC; Gormley, WT; Shaywitz, BA1
Michel, D; Mouret, J; Quenin, P; Renaud, B; Schott, B; Tommasi, M1
Rinne, UK; Siirtola, T; Sonninen, V1
Chase, TN; Glaubiger, GA; Woods, AC1
Engström, G; Svensson, TH; Waldeck, B1
Chase, TN; Ng, LK1
Chase, TN; Engel, WK; Mendell, JR2
Dunner, DL; Gershon, ES; Goodwin, FK1
Brody, JA; Chase, RN; Gordon, EK; Schnur, JA1
Johansson, B; Roos, BE1
Mlejnková, M; Rysánek, K; Spánková, H1
Axelrod, J; Goodwin, FK; Tamarkin, NR1
Bowers, MB; van Woert, MH1
Dresse, A; Gérardy, J; Quinaux, N1
Murphy, GF; Robinson, D; Sharman, DF1
Himmel, CD; Trulson, ME1

Reviews

6 review(s) available for dihydroxyphenylalanine and probenecid

ArticleYear
Biochemical plasticity of synaptic transmission: a critical review of Dale's Principle.
    Biological psychiatry, 1976, Volume: 11, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Brain; Carbidopa; Deamination; Dihydroxyphenylalanine; Evoked Potentials; Humans; Mental Disorders; Methyldopa; Neural Inhibition; Neurons; Neurotransmitter Agents; Phenethylamines; Probenecid; Rabbits; Rats; Receptors, Drug; Synapses; Synaptic Transmission; Visual Perception

1976
A critical assessment of methods for the determination of monoamine synthesis turnover rates in vivo.
    Advances in biochemical psychopharmacology, 1974, Volume: 12, Issue:0

    Topics: Amino Acids; Animals; Biogenic Amines; Carboxy-Lyases; Catecholamines; Chromatography, Gas; Dihydroxyphenylalanine; Dopamine; Evaluation Studies as Topic; Kinetics; Mass Spectrometry; Methods; Norepinephrine; Probenecid; Serotonin; Time Factors; Transaminases; Tritium; Tyrosine; Tyrosine 3-Monooxygenase

1974
Monoamine metabolites in lumbar CSF: the question of their origin in relation to clinical studies.
    Brain research, 1974, Oct-11, Volume: 79, Issue:1

    Topics: Animals; Biological Transport, Active; Brain; Cats; Cerebral Ventricles; Cerebrospinal Fluid; Choroid Plexus; Dihydroxyphenylalanine; Dogs; Dopamine; Fenclonine; Glycols; Haplorhini; Homovanillic Acid; Humans; Hydrocephalus; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Parkinson Disease; Phenylacetates; Probenecid; Serotonin; Spinal Cord; Spinal Cord Injuries; Tryptophan

1974
Drug-induced extrapyramidal disorders.
    Research publications - Association for Research in Nervous and Mental Disease, 1972, Volume: 50

    Topics: Antiparkinson Agents; Apomorphine; Basal Ganglia Diseases; Benztropine; Dihydroxyphenylalanine; Dopamine; Drug-Related Side Effects and Adverse Reactions; Extrapyramidal Tracts; Haloperidol; Humans; Methyltyrosines; Movement Disorders; Phenothiazines; Phenylacetates; Probenecid; Reserpine; Synaptic Transmission; Tetrabenazine; Tranquilizing Agents; Trihexyphenidyl

1972
[Biochemical and clinical correlations in Parkinson's disease].
    Revue neurologique, 1972, Volume: 127, Issue:2

    Topics: Brain; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Humans; Movement Disorders; Norepinephrine; Parkinson Disease; Probenecid

1972
Central dopamine function in affective illness: evidence from precursors, enzyme inhibitors, and studies of central dopamine turnover.
    Advances in biochemical psychopharmacology, 1974, Volume: 12, Issue:0

    Topics: Adult; Affective Symptoms; Anger; Bipolar Disorder; Central Nervous System; Depression; Diagnosis, Differential; Dihydroxyphenylalanine; Dopamine; Dopamine beta-Hydroxylase; Female; Homovanillic Acid; Humans; Male; Methyltyrosines; Middle Aged; Norepinephrine; Picolinic Acids; Probenecid; Psychiatric Nursing; Psychotic Disorders; Time Factors; Tyrosine

1974

Trials

4 trial(s) available for dihydroxyphenylalanine and probenecid

ArticleYear
Estimation of brain amine metabolism in affective illness: cerebrospinal fluid studies utilizing probenecid.
    Psychotherapy and psychosomatics, 1974, Volume: 23, Issue:1-6

    Topics: Bipolar Disorder; Brain; Depression; Dihydroxyphenylalanine; Fenclonine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methyltyrosines; Phenylacetates; Placebos; Probenecid; Stimulation, Chemical; Substance-Related Disorders; Tryptophan

1974
[Predictive value of the probenecid test for the effect of L-DOPA therapy in Parkinson's disease].
    Nature: New biology, 1972, Apr-19, Volume: 236, Issue:68

    Topics: Adult; Aged; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Evaluation Studies as Topic; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Stereoisomerism

1972
Parkinson disease treated with a suspected dopamine receptor agonist.
    Archives of neurology, 1974, Volume: 30, Issue:5

    Topics: Adult; Aged; Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Benztropine; Dihydroxyphenylalanine; Dopamine; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Muscle Rigidity; Parkinson Disease; Piperazines; Placebos; Probenecid; Pyrimidines; Receptors, Cholinergic; Tremor; Trihexyphenidyl

1974
The effect of L-DOPA treatment on brain serotonin metabolism in depressed patients.
    Life sciences. Pt. 1: Physiology and pharmacology, 1971, Jul-01, Volume: 10, Issue:13

    Topics: Brain; Depression; Dihydroxyphenylalanine; Humans; Hydroxyindoleacetic Acid; Phenylacetates; Placebos; Probenecid; Propionates; Serotonin

1971

Other Studies

32 other study(ies) available for dihydroxyphenylalanine and probenecid

ArticleYear
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Dual action of methadone on 5-HT synthesis and metabolism.
    Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 307, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Hydroxyindoleacetic Acid; Male; Methadone; Morphine; Naloxone; Probenecid; Rats; Serotonin; Tryptophan; Tyrosine

1979
Intragranular starch: comparison of starch USP and modified cornstarch.
    Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:2

    Topics: Acetaminophen; Ascorbic Acid; Biopharmaceutics; Cellulose; Chlorothiazide; Dihydroxyphenylalanine; Excipients; Hardness Tests; Kinetics; Methyldopa; Pressure; Probenecid; Solubility; Starch; Tablets

1975
Dopamine metabolism in depressions, psychoses, and Parkinson's disease: the problem of the specificity of biological variables in behaviour disorders.
    Psychological medicine, 1975, Volume: 5, Issue:2

    Topics: Adjustment Disorders; Bipolar Disorder; Brain; Carboxy-Lyases; Depression; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Humans; Motor Activity; Parkinson Disease; Probenecid; Psychomotor Disorders; Psychotic Disorders

1975
A comparison of the effects of carbon monoxide intoxication and low-oxygen gas mixtures on cerebral biogenic amine metabolism.
    Brain research, 1987, Apr-07, Volume: 408, Issue:1-2

    Topics: 5-Hydroxytryptophan; Animals; Carbon Monoxide Poisoning; Cerebral Cortex; Dihydroxyphenylalanine; Dopamine; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia, Brain; Male; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Serotonin

1987
Chronic cocaine administration decreases dopamine synthesis rate and increases [3H] spiroperidol binding in rat brain.
    Brain research bulletin, 1987, Volume: 19, Issue:1

    Topics: Animals; Brain Chemistry; Cocaine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Injections, Intraperitoneal; Kinetics; Limbic System; Male; Mesencephalon; Probenecid; Rats; Rats, Inbred Strains

1987
Predicting the response to levodopa.
    Lancet (London, England), 1971, May-15, Volume: 1, Issue:7707

    Topics: Calcinosis; Capillaries; Central Nervous System; Cerebrospinal Fluid; Cerebrovascular Disorders; Dihydroxyphenylalanine; Humans; Hypercalcemia; Injections, Intravenous; Male; Middle Aged; Parathyroid Diseases; Parkinson Disease; Phenylacetates; Physostigmine; Probenecid; Prognosis

1971
Predicting response to levodopa.
    Lancet (London, England), 1971, Jul-17, Volume: 2, Issue:7716

    Topics: Brain; Dihydroxyphenylalanine; Dopamine; Humans; Parkinson Disease; Phenylacetates; Probenecid; Time Factors

1971
The effect of hypoxia on monoamine synthesis, levels and metabolism in rat brain.
    Journal of neurochemistry, 1973, Volume: 21, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; Fluorometry; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypoxia; Kinetics; Male; Monoamine Oxidase Inhibitors; Norepinephrine; Probenecid; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase

1973
3 -Methoxy- 4 -hydroxyphenylethylene glycol in human cerebrospinal fluid.
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 35, Issue:1

    Topics: Chromatography, Gas; Depression; Dihydroxyphenylalanine; Down Syndrome; Ethers; Glycols; Humans; Hydroxyindoleacetic Acid; Parkinson Disease; Phenols; Phenylacetates; Probenecid

1971
Norepinephrine metabolism in the central nervous system of man: studies using 3-methoxy-4-hydroxyphenylethylene glycol levels in cerebrospinal fluid.
    Journal of neurochemistry, 1973, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Carbon Radioisotopes; Cerebrospinal Fluid; Child; Chromatography, Gas; Dihydroxyphenylalanine; Dopamine; Down Syndrome; Dystonia Musculorum Deformans; Female; Glycols; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Methyltyrosines; Middle Aged; Norepinephrine; Parkinson Disease; Picolinic Acids; Probenecid; Serotonin; Spinal Cord Diseases; Time Factors

1973
The monoamine metabolism in viral encephalitides of the mouse. II. Turnover of monoamines in mice infected with herpes simplex virus.
    Brain research, 1972, Sep-29, Volume: 44, Issue:2

    Topics: Animals; Brain; Dihydroxyphenylalanine; Disulfides; Dopamine; Herpes Simplex; Hydroxyindoleacetic Acid; Methyltyrosines; Mice; Norepinephrine; Pargyline; Phenylacetates; Probenecid; Reserpine; Serotonin; Simplexvirus

1972
Adenosine 3',5'-monophosphate in cerebrospinal fluid. Effect of drugs and neurologic disease.
    Archives of neurology, 1973, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Aged; Cerebellar Diseases; Child; Cyclic AMP; Dihydroxyphenylalanine; Female; Homovanillic Acid; Humans; Huntington Disease; Male; Middle Aged; Movement Disorders; Muscular Diseases; Parkinson Disease; Peripheral Nervous System Diseases; Probenecid; Spinal Cord Diseases

1973
Serotonergic-dopaminergic interactions and extrapyramidal function.
    Advances in biochemical psychopharmacology, 1974, Volume: 11, Issue:0

    Topics: Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; Extrapyramidal Tracts; Humans; Huntington Disease; Motor Activity; Nerve Degeneration; Neurons; Parkinson Disease; Probenecid; Serotonin; Stereotaxic Techniques; Synaptic Transmission

1974
Dopaminergic nervous transmission in Parkinson's disease.
    Medical biology, 1974, Volume: 52, Issue:3

    Topics: Acetylcholinesterase; Aromatic Amino Acid Decarboxylase Inhibitors; Autopsy; Brain; Brain Chemistry; Dihydroxyphenylalanine; DNA; Dopa Decarboxylase; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Norepinephrine; Parkinson Disease; Probenecid; RNA; Serotonin; Stimulation, Chemical; Synaptic Transmission; Time Factors

1974
Accumulation of 3H-homovanillic acid in rabbit brain and cerebrospinal fluid following intravenous 3H-L-dopa.
    Biological psychiatry, 1974, Volume: 9, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Carboxy-Lyases; Cerebrospinal Fluid; Chlorpromazine; Chromatography, Thin Layer; Deamination; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Injections, Intravenous; Male; Methylation; Neurons; Phenylacetates; Probenecid; Rabbits; Stimulation, Chemical; Time Factors; Tritium

1974
Mechanisms for the efflux of [14C]DOPA and[14C]dopamine from the CSF of rhesus monkeys.
    Journal of neurochemistry, 1972, Volume: 19, Issue:7

    Topics: Animals; Benzyl Compounds; Carbon Isotopes; Caudate Nucleus; Chromatography, Gas; Dihydroxyphenylalanine; Dopamine; Female; Haplorhini; Hydrazines; Macaca; Male; Mathematics; Mesencephalon; Methyltyrosines; Norepinephrine; Perfusion; Probenecid; Serine

1972
[Monoamines and the regulation of wakefulness. II. Lesional syndromes of the central nervous system].
    Revue neurologique, 1972, Volume: 127, Issue:1

    Topics: Attention; Brain Diseases; Catecholamines; Coma; Dihydroxyphenylalanine; Electroencephalography; Eye Movements; Humans; Probenecid; Serotonin; Sleep; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Time Factors; Wakefulness

1972
Acid monoamine metabolites in the cerebrospinal fluid of Parkinsonian patients treated with levodopa alone or combined with a decarboxylase inhibitor.
    European neurology, 1973, Volume: 9, Issue:6

    Topics: Adult; Aged; Carboxy-Lyases; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Libido; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Serotonin

1973
Thyroxine and brain catecholamines: increased transmitter synthesis and increased receptor sensitivity.
    Brain research, 1974, Sep-13, Volume: 77, Issue:3

    Topics: Animals; Brain; Clonidine; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Exploratory Behavior; Female; Heart; Homovanillic Acid; Locomotion; Male; Mice; Norepinephrine; Organ Size; Probenecid; Receptors, Adrenergic; Reserpine; Stimulation, Chemical; Thyroxine; Tritium; Tyrosine

1974
Fusaric acid in Parkinson's disease.
    Neurology, 1974, Volume: 24, Issue:7

    Topics: Aged; Antiparkinson Agents; Dihydroxyphenylalanine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Parkinson Disease; Picolinic Acids; Probenecid

1974
Central monoamine metabolism in Parkinson's disease.
    Archives of neurology, 1972, Volume: 27, Issue:6

    Topics: Adult; Aged; Dihydroxyphenylalanine; Dopamine; Evaluation Studies as Topic; Female; Humans; Hydroxyindoleacetic Acid; Male; Methyldopa; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Serotonin

1972
Amyotrophic lateral sclerosis. A study of central monoamine metabolism and therapeutic trial of levodopa.
    Archives of neurology, 1971, Volume: 25, Issue:4

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Dihydroxyphenylalanine; Dopamine; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Phenylacetates; Probenecid

1971
Parkinsonism-dementia and amyotrophic lateral sclerosis of Guam. Effect of probenecid on monoamine catabolite levels in cerebrospinal fluid.
    Archives of neurology, 1971, Volume: 25, Issue:1

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Dihydroxyphenylalanine; Dopamine; Female; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Micronesia; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Serotonin

1971
5-Hydroxyindoleacetic acid in cerebrospinal fluid of patients with Parkinson's syndrome treated with L dopa.
    European journal of clinical pharmacology, 1971, Volume: 3, Issue:4

    Topics: Adult; Aged; Dihydroxyphenylalanine; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Serotonin

1971
Amyotrophic lateral sclerosis: metabolism of central monoamines and treatment with L-dopa.
    Transactions of the American Neurological Association, 1971, Volume: 96

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Central Nervous System; Dihydroxyphenylalanine; Dopamine; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Phenylacetates; Probenecid; Serotonin

1971
The way of excretion of 5-hydroxyindole acetic acid.
    Activitas nervosa superior, 1970, Jan-12, Volume: 12, Issue:1

    Topics: Administration, Oral; Aminohippuric Acids; Animals; Dihydroxyphenylalanine; Drug Antagonism; Humans; Hydroxyindoleacetic Acid; Probenecid

1970
Rapid elevation of biogenic amine metabolites in human CSF following probenecid.
    Life sciences. Pt. 1: Physiology and pharmacology, 1970, Dec-15, Volume: 9, Issue:24

    Topics: Administration, Oral; Affective Symptoms; Dihydroxyphenylalanine; Female; Headache; Humans; Hydroxyindoleacetic Acid; Male; Methadone; Nausea; Phenylacetates; Probenecid; Spinal Puncture; Vomiting

1970
Homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5HIAA) during L-dopa therapy of Parkinson's disease.
    Neurology, 1970, Volume: 20, Issue:4

    Topics: Dementia; Dihydroxyphenylalanine; Humans; Hydroxyindoleacetic Acid; Parkinson Disease; Phenylacetates; Probenecid

1970
[Determination of noradrenaline, of dopamine and dihydroxyphenylacetic acid in certain nuclei of rat brain].
    Experientia, 1971, Jan-15, Volume: 27, Issue:1

    Topics: Animals; Ascorbic Acid; Catecholamines; Caudate Nucleus; Chromatography, Thin Layer; Dihydroxyphenylalanine; Dopamine; Female; Fluorometry; Haloperidol; Hypothalamus; Male; Norepinephrine; Phenylacetates; Probenecid; Rats; Reserpine; Tranylcypromine

1971
The effect of tropolone on the formation of 3,4-dihydroxyphenylacetic acid and 4-hydroxy-3-methoxyphenylacetic acid in the brain of the mouse.
    British journal of pharmacology, 1969, Volume: 36, Issue:1

    Topics: Animals; Brain; Cycloparaffins; Dihydroxyphenylalanine; Female; Fluorometry; Ketones; Mice; Phenylacetates; Probenecid

1969
Decreased brain dopamine synthesis rate and increased [3H]spiroperidol binding in streptozotocin-diabetic rats.
    Journal of neurochemistry, 1983, Volume: 40, Issue:5

    Topics: Animals; Brain; Butyrophenones; Diabetes Mellitus, Experimental; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Insulin; Kinetics; Probenecid; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone

1983