dihydroxyphenylalanine has been researched along with methyldopa in 296 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 285 (96.28) | 18.7374 |
| 1990's | 7 (2.36) | 18.2507 |
| 2000's | 3 (1.01) | 29.6817 |
| 2010's | 1 (0.34) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Davidson, L; Hornykiewicz, O; Lloyd, KG | 1 |
| Borison, RL; Giardina, WJ; Mosnaim, AD; Pedemonte, WA; Sabelli, HC; Vazquez, AJ | 1 |
| Owen, CA; Sharpless, NS; Tyce, GM | 2 |
| Kato, T; Nagatsu, T; Oka, K | 1 |
| Cier, JF; Miachon, S; Peyrin, L | 1 |
| Huszti, Z; Sourkes, TL | 1 |
| Aubry, M; Bey, P; Danzin, C; Jung, MJ; Palfreyman, MG; Ribereau-Gayon, G; Sjoerdsma, A; Vevert, JP | 1 |
| Comi, R; Fahn, S; Prasad, AL; Snider, SR | 1 |
| Asmus, PA; Freed, CR | 1 |
| Ernst, AM | 2 |
| Henning, M | 1 |
| Castagnoli, N; Freed, CR; Melmon, KL; Weinkam, RJ | 1 |
| Thut, PD | 1 |
| Ames, MM; Gal, J | 1 |
| Banda, PW; Blois, MS | 1 |
| Geissbühler, F; Widmer, J | 1 |
| Kyncl, J; Minard, F; Plotnikoff, N; Rasmussen, R; Winn, M | 1 |
| Grechishkin, LL | 1 |
| Sabelli, HC; Vazquez, AJ | 1 |
| Charvet, JC; Greffe, J; Mathieu, P | 1 |
| Dehner, EJ; Martin, ET; Schwartz, JB | 1 |
| Firnau, G; Garnett, ES; Missala, K; Sourkes, TL | 1 |
| Loriga, M; Paglietti, G; Pinna, G; Sisini, A; Sparatore, F | 1 |
| Bjurling, P; Hartvig, P; Hörnfelt, K; Långström, B; Lindner, KJ; Tedroff, J | 1 |
| De Klippel, N; Deleu, D; Ebinger, G; Herregodts, P; Michotte, Y; Sarre, S | 1 |
| Melzi d'Eril, GV; Rizzo, V | 1 |
| Bazan, E; de Yebenes, JG; Mena, MA; Muradas, V; Reiriz, J | 1 |
| Nagatsu, T; Naoi, M | 1 |
| Garty, M; Goldstein, DS; Rosenfeld, JB; Steinmetz, Y | 1 |
| Altschule, MD; Hegedus, ZL | 2 |
| Chase, TN; Ng, L; Passananti, GT; Vesell, ES | 1 |
| Gerstenbrand, F; Gründig, E; Schedl, R; Simanyi, M; Weiss, H | 1 |
| Chase, TN; Fermaglich, J | 1 |
| Gray, RM; Harrison, WH; Solomon, LM | 1 |
| Hornykiewicz, O | 1 |
| Lotti, VJ; Stone, CA; Torchiana, ML | 1 |
| van Zwieten, PA | 1 |
| Atkins, FL; Beaven, MA; Keiser, HR | 1 |
| Dhasmana, KM; Spilker, BA | 1 |
| Clark, CM; Lotti, VJ; Stone, CA; Torchiana, ML | 1 |
| Coquillat, G; Kurtz, D; Mack, G; Maitrot, D; Mandel, P; Micheletti, G; Rohmer, F; Warter, JM | 1 |
| Grunstein, JA | 1 |
| Benoiton, NL; D'lorio, A; Sharma, S; Tong, JH | 1 |
| Munro, HN; Roel, LE; Weiss, BF; Wurtman, RJ | 1 |
| Cotzias, GC; Gellene, R; Papavasiliou, PS | 1 |
| Crawford, JP | 1 |
| Böszörményi, Z; Villeneuve, A | 1 |
| Chang, CP | 1 |
| Curzon, G | 1 |
| Hartmann-von Monakow, K | 1 |
| Andén, NE; Engel, J; Rubenson, A | 1 |
| Dunkley, B; Friedman, E; Gershion, S; Sanghvi, I | 1 |
| Constantinidis, J | 1 |
| Senault, B | 1 |
| Modigh, K | 1 |
| Cotzias, GC; Mena, I; Tang, LC | 1 |
| Kopin, IJ; Sedvall, GC; Weise, VK | 1 |
| Brodie, HK; Bunney, WE; Goodwin, FK; Murphy, DL | 1 |
| Robson, RD | 1 |
| Boyd, AE; Feldman, JM; Lebovitz, HE | 1 |
| Gershon, S; Wallach, MB | 2 |
| Delesie, R; Fahn, S; Prasad, AL | 1 |
| Creveling, CR; Daly, J; Morris, N; Ong, HH; Shimizu, H | 1 |
| Chang, BL; Grabowski, BF; Haney, WG | 1 |
| Schwartz, RS; Weens, JH | 1 |
| Norberg, KA | 1 |
| Farmer, JB | 1 |
| Zenker, N | 1 |
| Radwan, AG; West, GB | 1 |
| Bliss, EL; Eyzaguirre, C; Hess, A; Zapata, P | 1 |
| Bartholini, G; Pletscher, A | 3 |
| McGill, JS; Pruss, TP | 1 |
| Day, MD; Owen, DA | 1 |
| Rubenson, A | 1 |
| Porter, CC; Torchiana, ML | 1 |
| Henning, M; Rubenson, A | 1 |
| Karobath, M | 1 |
| Baldessarini, RJ | 1 |
| Axelrod, J; Weinshilboum, R | 1 |
| Eichelman, B; Ng, KY; Thoa, NB | 1 |
| Munro, HN; Ordonez, LA; Weiss, BF; Wurtman, RJ | 1 |
| Henning, M; Rubenson, A; Trolin, G | 1 |
| Bolme, P; Fuxe, K; Lidbrink, P | 1 |
| Calne, DB; Reid, JL | 2 |
| Costea, N; Eipe, J | 1 |
| Rivera-Calimlim, L | 1 |
| Dinapoli, RP; Muenter, MD; Sharpless, NS; Tyce, GM | 2 |
| Kledzik, GS; Meites, J | 1 |
| Horvath, TB; Meares, RA | 1 |
| Hare, TA; Mahoney, K; Vogel, WH | 1 |
| Abou, YZ; Adam, HM; Stephen, WR | 1 |
| González-Bárcena, D; Guzmán-Rangel, Y; López-Luna, M; Siller-Rodríguez, J | 1 |
| Bell, MA; Cotzias, GC; Düby, SE; Fehling, C; Papavasiliou, PS; Steck, AJ | 1 |
| Johnson, DG; Kopin, IJ; Thoa, NB | 1 |
| Duvoisin, RC; Yahr, MD | 1 |
| Allen, JG; Calne, DB; Davies, CA; Reid, JL; Vakil, SD | 1 |
| Calne, DB; Hilson, A; Rao, SK; Vakil, SD | 1 |
| Gibberd, FB; Small, E | 1 |
| Buse, MG; Rossini, AA | 1 |
| Presthus, J | 1 |
| Mones, RJ | 1 |
| Kadzielawa, K | 2 |
| Furuta, Y; Hashimoto, K; Ishii, Y; Iwatsuki, K | 1 |
| Anagnoste, B; Battista, AF; Fuxe, K; Goldstein, M; Ohmoto, T | 1 |
| Bianchine, JR; Hsu, TH; Messiha, FS | 1 |
| Calne, DB; George, CF; Reid, JL; Vakil, SD | 1 |
| Baldessarini, RJ; Karobath, M | 1 |
| Chase, TN; Colburn, RW; Kopin, IJ; Ng, LK | 1 |
| Weinberg, HB | 1 |
| Mars, H | 1 |
| Kledzik, GS; Meites, J; Quadri, SK | 1 |
| Jaeger, I; Lippold, BC | 1 |
| Kofman, OS | 1 |
| Hashida, J | 1 |
| Bartholini, G; Constantinidis, J; de Ajuriaguerra, J; Eisenring, JJ; Geissbühler, F; Tissot, R; Yanniotis, G | 1 |
| Antikainen, PJ; Witikainen, U | 1 |
| Calesnick, B; Irvin, JD; Mathews, GJ; Osterholm, JL | 1 |
| Morrison, AB; Webster, RA | 1 |
| Atkinson, M; Hartley, D; Lunts, LH; Ritchie, AC | 1 |
| Bartholini, G; Lloyd, KG; Pletscher, A | 1 |
| Crespin, SR; Jarett, L; Smith, RM | 1 |
| Duvoisin, RC; Marsden, CD | 1 |
| Fahn, S; Prasad, AL | 1 |
| Andersson, B; Hovmöller, S; Karlsson, CG; Svensson, S | 1 |
| Bell, MA; Mena, I; Potter, DW | 1 |
| Tran, N | 1 |
| Fahn, S | 1 |
| Laverty, R; Taylor, KM | 1 |
| Degkwitz, R | 1 |
| Bartholini, G; Kuruma, I; Pletscher, A | 3 |
| Cotzias, GC; Ginos, JZ; Nicholson, AR; Papavasiliou, PS; Tang, L | 1 |
| Calne, DB; Gawler, J; Hilson, A; Pallis, CA; Petrie, A; Rao, S; Reid, JL; Thomas, PK; Vakil, SD | 1 |
| Bencosme, SA; Berger, JM | 1 |
| Ehinger, B; Falck, B | 2 |
| Anagnoste, B; Battista, AF; Goldstein, M; Nakatani, S | 1 |
| Anton-Lamprecht, I; Jung, EG | 1 |
| Gault, MH; Hebert, MA; Singh, HP | 1 |
| Calne, DB; Petrie, A; Rao, S; Reid, JL; Vakil, SD | 1 |
| Curzon, G; Kantamaneni, BD; Trigwell, J | 1 |
| Muenter, MD; Owen, CA; Sharpless, NS; Tyce, GM | 1 |
| Spoerlein, MT; Vander Wende, C | 1 |
| Jonsson, G; Sachs, C | 1 |
| Eisenring, JJ; Gaillard, JM; Geissbühler, F; Krassoievitch, M; Tissot, R; Yanniotis, G | 1 |
| Macleod, VH | 1 |
| Muenter, MD; Sharpless, NS; Tyce, GM | 1 |
| Chase, TN; Watanabe, AM | 1 |
| Barrera, ER; Bennett, S; Mars, H | 1 |
| Colburn, RW; Kopin, IJ; Ng, LK | 1 |
| Chase, TN; Ng, LK | 1 |
| Finch, L | 1 |
| Constantinidis, J; Eisenring, JJ; Geissbühler, F; Krassoievitch, M; Tissot, R; Yanniotis, G | 1 |
| Dankova, J; Davidson, L; Hornykiewicz, O; Lloyd, K | 1 |
| Krall, J; Mars, H | 1 |
| Tyce, GM | 1 |
| Landsberg, L | 1 |
| Fähse, C; Lietz, W; Matthies, H | 2 |
| Fermaglich, J; O'Doherty, DS | 1 |
| Barrett, RE; Duvoisin, RC; Mendoza, MR; Schear, MJ; Yahr, MD | 1 |
| Lee, JE; McDowell, F; Sweet, RD | 1 |
| Kerkut, GA; Ralph, KL; Walker, RJ; Woodruff, GN | 1 |
| Cotzias, GC | 1 |
| Koe, BK; Weissman, A | 1 |
| De Ropp, RS; Furst, A | 1 |
| Kawabata, K | 1 |
| Brown, RM; Lal, H | 1 |
| Chase, TN | 1 |
| Beaven, MA; Gordon, JW; Jacobsen, S; Severs, WB | 1 |
| Zabrodin, ON | 1 |
| Colburn, RW; Kopin, IJ; Ng, KY | 1 |
| Fyfe, RM | 1 |
| Holldorf, A; Metzel, A; Umbach, W | 1 |
| Hanson, LC; Henning, M | 1 |
| Bartholini, G; Pletscher, A; Tissot, R | 1 |
| Glowinski, J; Kordon, C | 1 |
| Moran, JF; Murphy, GF; Saint Cyr, S; Sourkes, TL; Wiseman-Distler, H | 1 |
| Hajós, A; Sohár, P | 1 |
| Coppola, JA; Leonardi, RG; Lippmann, W; Perrine, JW; Ringler, I | 1 |
| Gunne, LM | 1 |
| Carlsson, A; Utley, JD | 1 |
| Sharma, VN; Sogani, RK | 1 |
| Weber, LJ | 2 |
| Laasberg, LH; Shimosato, S | 1 |
| Ludden, CT; Stavorski, J; Stone, CA; Torchiana, ML; Wenger, HC | 1 |
| Bhagat, B; Dhalla, NS; Gray, L | 1 |
| Mennear, JH; Rudzik, AD | 1 |
| Burcin, A; Porter, CC; Totaro, JA; Wynosky, ER | 1 |
| Kerkut, GA; Sedden, CB; Walker, RJ | 1 |
| Travenets, IA | 1 |
| Aebert, K | 1 |
| Parkinson, D; Rando, RR | 1 |
| D'Erme, M; Di Stazio, G; Fiori, A; Rosei, MA | 1 |
| Garibova, TL; Voronina, TA | 1 |
| de Jong, HJ; Janssen, HJ; Tjaden, UR; Wahlund, KG | 1 |
| Kehr, W; Thiede, HM | 1 |
| Iwao, J; Kato, E; Kawashima, Y; Matsumoto, J; Oya, M | 1 |
| Baughman, R; Masland, RH; Parkinson, D; Rando, RR | 1 |
| Fujita, Y; Kawano, T; Maemura, S; Niwa, M; Ozaki, M | 1 |
| Jung, MJ; Palfreyman, MG; Ribéreau-Gayon, G; Wagner, J; Zraïka, M | 1 |
| Ary, K; Gachályi, B; Klebovich, I; Róna, K | 1 |
| Carlson, J; Gao, H; Heineman, WR; Stalcup, AM | 1 |
| Gübitz, G; Kilár, F; Schmid, MG; Végvári, A | 1 |
| Dolezalová, M; Fanali, S | 1 |
| Parada, A; Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
| BALZER, H; KNELL, J; WESTERMANN, E | 1 |
| DENGLER, H; REICHEL, G | 1 |
| COLLINI, FJ | 1 |
| CLOSE, JH; GOGERTY, JG; PAYNE, RW; WHITSETT, TL | 1 |
| OATES, JA; SJOERDSMA, A; UDENFRIEND, S; ZALTZMAN, P | 1 |
| SMITH, SE | 1 |
| ARNOLD, OH | 1 |
| BAUMGARTEN, A | 1 |
| BAYLISS, RI; HARVEY-SMITH, EA | 1 |
| ANGERS, M; CANNON, PJ; LARAGH, JH; MORRIS, RC; WHITLOCK, RT | 1 |
| CARLSSON, A; LINDQVIST, M | 1 |
| DALEY, D; EVANS, B | 1 |
| ADICOFF, A; ALEXANDER, CS; DAVIS, RB | 1 |
| DOLLERY, CT; HARINGTON, M | 1 |
| DOYLE, A; TREVAKS, G | 1 |
| DRAIN, DJ; HORLINGTON, M; LAZARE, R; POULTER, GA | 1 |
| BLUMBERG, A; DUBACH, UC | 1 |
| FELLINGER, K; GRABNER, G; KRYGICZ, H | 1 |
| CARTIER, P; FABLET, J; GEFFROY, Y; LEGRAND, M; LEMOINE, P; MALANDRIN, C; MOREAU, J | 1 |
| CROUT, JR; GILLESPIE, L; OATES, JA; SJOERDSMA, A | 1 |
| HALLWRIGHT, GP | 2 |
| CONNAMACHER, RH; HESS, SM; OZAKI, M; UDENFRIEND, S | 1 |
| BLESSING, JA; LUDDEN, CT; PORTER, CC; ROSS, CA; STONE, CA; TOTARO, JA; WENGER, HC | 1 |
| LAIBSON, PR; LEOPOLD, IH | 1 |
| KUNO, Y; OYA, T | 1 |
| GIFFORD, RW; TWEED, DC | 1 |
| GOLDBERG, LI; ZIMMERMAN, AM | 1 |
| BAILA, MR; CINTAS, JA | 1 |
| ROOS, BE; WERDINIUS, B | 1 |
| SCHAER, H; ZIEGLER, WH | 1 |
| LEBLANC, J; POULIOT, M | 1 |
| DEGRAFF, AC; SPERBER, RJ | 1 |
| URBINATI, GC | 1 |
| FISHER, FD; KIRKENDALL, WM; WILSON, WR | 1 |
| BONVARLET, A; DREUX, C; DUHAMEL, J; SAVIER, CH; WELTI, JJ | 1 |
| ALEKSANDROW, D; JANUSZEWICZ, W; WOCIAL, B | 1 |
| DAVIS, RA; DRAIN, DJ; HORLINGTON, M; LAZARE, R; URBANSKA, A | 1 |
| DOLLERY, CT | 1 |
| COENEGRACHT, JM; HOLSHUYSEN, N; KOSTER, M; van DOMMELEN, C | 1 |
| ITO, Y; KAJIHARA, T; KISHII, T; KOBAYASHI, T; KOMIZO, H; NAGATA, Y; SHIMIZU, K | 1 |
| HALLIWELL, G; QUINTON, RM | 1 |
| JIMENEZCASADO, M; NAVARRO, V; RAPADOERRAZTI, A; RODRIGUEZSANTOS, A | 1 |
| BESSIRARD, D; DRUDI-BARACCO, C; HALPERN, BN | 1 |
| BRUSCA, A | 1 |
| DEIMEL, M; HEMPEL, K | 1 |
| ROSSI, GV; WEISS, B | 1 |
| TSOU, K; TU, ZH | 1 |
| SMITH, CB | 1 |
| CONTRERAS, E; CROXATTO, R; HUIDOBRO, F | 1 |
| BARRNETT, RJ; LENTZ, TL | 1 |
| FRITEL, D | 1 |
| MAITRE, L; STAEHELIN, M | 1 |
| BAN, TA; DONALD, MW; SAINTJEAN, A | 1 |
| BENZI, G | 1 |
| DAY, MD; RAND, MJ | 1 |
| IPPEN, H | 1 |
| JACOBY, GA; LADU, BN | 1 |
| CARDOT, J | 1 |
| CHEMERDA, JM; JACOB, TA; VITALI, RA | 1 |
| EDWARDS, KD; YOUNG, JA | 1 |
| BARRE, N; CAHN, J; HEROLD, M | 1 |
| LEVINE, RJ; SJOERDSMA, A | 1 |
| BROWN, WT; MURPHY, GF; PIVNICKI, D; SAINTCYR, S; SANKOFF, I; SOURKES, TL; WISEMAN-DISTLER, H | 1 |
| MORAN, JF; SOURKES, TL | 1 |
| RIPKA, O | 1 |
| CHO, MH; DOBKIN, AB; LEE, PK | 1 |
| KIRKENDALL, WM; WILSON, WR | 1 |
| GIFFORD, RW; HUMPHREY, DC; LEONARD, JW | 1 |
| LEROY, JG | 1 |
| MATHISEN, HS | 1 |
| NECINA, J | 1 |
| IRVINE, RO; NICHOLSON, GI | 1 |
| NOBLE, NR | 1 |
| BREST, AN; MOYER, JH; NOVACK, P; ONESTI, G | 1 |
| LICHTLEN, P; NAGER, F; SCHAER, H; SCHAUB, F; ZIEGLER, W | 1 |
| Borst, C; Holzgrabe, U | 1 |
20 review(s) available for dihydroxyphenylalanine and methyldopa
| Article | Year |
|---|---|
Biochemical plasticity of synaptic transmission: a critical review of Dale's Principle.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carbidopa; Deamination; Dihydroxyphenylalanine; Evoked Potentials; Humans; Mental Disorders; Methyldopa; Neural Inhibition; Neurons; Neurotransmitter Agents; Phenethylamines; Probenecid; Rabbits; Rats; Receptors, Drug; Synapses; Synaptic Transmission; Visual Perception | 1976 |
Compulsive gnawing.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Behavior, Animal; Benserazide; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Iproniazid; Levodopa; Male; Methyldopa; Methyltyrosines; Rats; Serotonin; Structure-Activity Relationship; Time Factors | 1976 |
Central sympathetic transmitters and hypertension.
Topics: Acetylcholine; Animals; Blood Pressure; Cardiac Output; Cats; Clonidine; Dihydroxyphenylalanine; Dogs; Heart Rate; Humans; Hypertension; Methyldopa; Nordefrin; Norepinephrine; Rabbits; Rats; Serotonin | 1975 |
Parkinson's disease: from brain homogenate to treatment.
Topics: Animals; Brain; Caudate Nucleus; Corpus Striatum; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Dose-Response Relationship, Drug; Globus Pallidus; Homovanillic Acid; Humans; Methyldopa; Parkinson Disease; Phenylacetates; Receptors, Drug; Substantia Nigra; Tyrosine 3-Monooxygenase | 1973 |
The central action of antihypertensive drugs, mediated via central alpha-receptors.
Topics: Adrenergic alpha-Antagonists; Amphetamine; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cardiac Output; Cats; Clonidine; Dihydroxyphenylalanine; Methyldopa; Norepinephrine; Receptors, Adrenergic; Reserpine; Sympathetic Nervous System; Vagus Nerve; Vascular Resistance | 1973 |
The biochemistry of dyskinesias.
Topics: Acetylcholine; Animals; Catecholamines; Cats; Copper; Dihydroxyphenylalanine; Dogs; Hepatolenticular Degeneration; Humans; Huntington Disease; Manganese Poisoning; Melanins; Metals; Methyldopa; Movement Disorders; Parkinson Disease; Phenothiazines; Rabbits; Rats; Reserpine; Serotonin; Telencephalon; Tremorine | 1967 |
Effects of inhibitors and stimulators of protein synthesis on the cerebral actions of L-dopa.
Topics: Animals; Behavior, Animal; Brain; Caudate Nucleus; Chloramphenicol; Cycloheximide; Dactinomycin; Dihydroxyphenylalanine; Growth Hormone; Male; Methyldopa; Mice; Motor Activity; Nerve Tissue Proteins; Niacinamide; Puromycin; Time Factors | 1973 |
Etiologic factors in autoimmune hemolytic anemia.
Topics: Agglutinins; Anemia, Hemolytic, Autoimmune; Animals; Antibody Formation; Autoantibodies; Binding Sites, Antibody; Cold Temperature; Cytomegalovirus; Dihydroxyphenylalanine; DNA; Histocompatibility Antigens; Humans; Immune Tolerance; Immunogenetics; Immunoglobulin E; Immunologic Deficiency Syndromes; Immunosuppression Therapy; Infectious Mononucleosis; Leukemia; Lymphocyte Activation; Lymphocytes; Mefenamic Acid; Methyldopa; Mice; Mitogens; Mycoplasma; Mycoplasma Infections; RNA Viruses; Syphilis; T-Lymphocytes | 1974 |
Catecholamines.
Topics: Adrenal Medulla; Affective Symptoms; Animals; Brain; Catechol O-Methyltransferase; Catecholamines; Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; Humans; Hypertension; Methyldopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nerve Endings; Neurons; Parkinson Disease; Receptors, Drug; Sympathetic Nervous System; Sympathomimetics; Synaptic Transmission; Tyrosine; Tyrosine 3-Monooxygenase | 1972 |
On the function of central catecholamine neurons--their role in cardiovascular and arousal mechanisms.
Topics: Adrenergic alpha-Antagonists; Animals; Bradycardia; Brain; Cardiovascular Physiological Phenomena; Catecholamines; Cats; Cerebral Cortex; Clonidine; Dihydroxyphenylalanine; Dopamine; Electric Stimulation; Hypotension; Methyldopa; Neurons; Norepinephrine; Receptors, Cholinergic; Stimulation, Chemical | 1972 |
Antiparkinsonian drugs: pharmacological and therapeutic aspects.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Amantadine; Amphetamine; Antiparkinson Agents; Apomorphine; Basal Ganglia Diseases; Carboxy-Lyases; Dihydroxyphenylalanine; Dopamine; Histamine H1 Antagonists; Humans; Mental Disorders; Methyldopa; Movement Disorders; Norepinephrine; Parasympatholytics; Serotonin; Synaptic Transmission | 1972 |
Drug therapy of parkinsonism.
Topics: Amantadine; Amitriptyline; Amphetamine; Antiparkinson Agents; Dihydroxyphenylalanine; Drug Antagonism; Drug Synergism; Humans; Imipramine; Methyldopa; Monoamine Oxidase Inhibitors; Parasympatholytics; Parkinson Disease; Phenothiazines | 1972 |
Drugs affecting monoamines in the basal ganglia.
Topics: Amines; Animals; Atropine; Barbiturates; Basal Ganglia; Biogenic Amines; Carbon Isotopes; Chlorpromazine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Haloperidol; Hydroxyindoleacetic Acid; Methyldopa; Norepinephrine; Phenylacetates; Rabbits; Rats; Tranquilizing Agents; Tritium | 1972 |
Augmenting the action of levodopa.
Topics: Amantadine; Antacids; Apomorphine; Carboxy-Lyases; Catechol O-Methyltransferase Inhibitors; Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; Drug Synergism; Humans; Methyldopa; Monoamine Oxidase Inhibitors; Parasympatholytics; Parkinson Disease | 1972 |
[Other trials with drug therapy in parkinsonism].
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Dihydroxyphenylalanine; Disulfiram; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Methyldopa; Monoamine Oxidase Inhibitors; Parkinson Disease; Picolinic Acids; Rats; Serine; Time Factors; Tryptophan; Tyrosine | 1973 |
[l-dopa treatment of Parkinson's syndrome and mechanism of action of neuroleptics].
Topics: Acetylcholine; Basal Ganglia; Butyrophenones; Chorea; Dihydroxyphenylalanine; Dopamine; Extrapyramidal Tracts; Humans; Methyldopa; Monoamine Oxidase Inhibitors; Parkinson Disease; Parkinson Disease, Secondary; Phenothiazines; Reserpine; Tranquilizing Agents; Xanthenes | 1969 |
Specific granules in mammalian and non-mammalian vertebrate cardiocytes.
Topics: Animals; Atropine; Bethanechol Compounds; Catecholamines; Cats; Cattle; Cytoplasmic Granules; Dihydroxyphenylalanine; Fishes; Heart Atria; Heart Ventricles; Hemicholinium 3; Histocytochemistry; Humans; Isoproterenol; Lysosomes; Methyldopa; Microscopy, Electron; Myocardium; Nialamide; Norepinephrine; Propranolol; Rabbits; Rats; Reserpine; Sympatholytics; Sympathomimetics | 1971 |
[THERAPY OF ESSENTIAL HYPERTENSION].
Topics: Adrenalectomy; Antihypertensive Agents; Benzothiadiazines; Coronary Disease; Diazoxide; Diet; Dihydroxyphenylalanine; Diuretics; Essential Hypertension; Ganglionic Blockers; Hydralazine; Hypertension; Hypertension, Renal; Intracranial Arteriosclerosis; Methyldopa; Mineralocorticoid Receptor Antagonists; Personality; Rauwolfia; Sympathectomy; Sympatholytics | 1963 |
[THE MEDICAMENTOUS TREATMENT OF COMMON ARTERIAL HYPERTENSION].
Topics: Antihypertensive Agents; Benzothiadiazines; Dihydroxyphenylalanine; Ganglionic Blockers; Guanethidine; Hydralazine; Hypertension; Methyldopa; Rauwolfia | 1963 |
[ON THE PROBLEMS OF RESEARCH ON PIGMENTATION].
Topics: Antihypertensive Agents; Biomedical Research; Central Nervous System Stimulants; Dihydroxyphenylalanine; Humans; Indoles; Melanins; Melanoma; Methyldopa; Monoamine Oxidase Inhibitors; Pigmentation; Pigmentation Disorders; Research; Sympathomimetics; Tranquilizing Agents | 1964 |
13 trial(s) available for dihydroxyphenylalanine and methyldopa
| Article | Year |
|---|---|
Methyldopa or methyldopahydrazine as levodopa synergists.
Topics: Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Humans; Hydrazines; Methyldopa; Parkinson Disease | 1973 |
[Pharmacological and biochemical approach to a syndrome of action and intention myoclonus in the course of degenerative disease of the nervous system].
Topics: 5-Hydroxytryptophan; Adult; Benzazepines; Cerebellar Ataxia; Clinical Trials as Topic; Diagnosis, Differential; Dibenzazepines; Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; Electroencephalography; Epilepsy; Friedreich Ataxia; Humans; Hydroxyindoleacetic Acid; Ketones; Male; Methyldopa; Methysergide; Myoclonus; Neurotransmitter Agents; Nitro Compounds; Pyridoxine; Serotonin; Synaptic Transmission; Tranquilizing Agents | 1973 |
Modification of Parkinsonism--chronic treatment with L-dopa.
Topics: Adult; Aged; Agranulocytosis; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Urea Nitrogen; Blood-Brain Barrier; Chronic Disease; Dihydroxyphenylalanine; Dopamine; Feeding and Eating Disorders; Female; Humans; Huntington Disease; Male; Manganese; Mental Processes; Methyldopa; Middle Aged; Movement Disorders; Nausea; Neurologic Manifestations; Parkinson Disease; Phenylacetates; Placebos; Thyroid Function Tests; Tyrosine; Vomiting | 1969 |
Treatment of drug-induced dyskinesias.
Topics: Aged; Dihydroxyphenylalanine; Humans; Methyldopa; Middle Aged; Movement Disorders; Parkinson Disease; Reserpine | 1970 |
Regular induction of hypomania by L-dopa in "bipolar" manic-depressive patients.
Topics: Antidepressive Agents; Bipolar Disorder; Catecholamines; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Euphoria; Female; Humans; Hydrazines; Male; Methyldopa; Methyltyrosines; Middle Aged; Phenylacetates; Placebos; Psychomotor Disorders; Sleep, REM; Stereoisomerism; Visual Cortex | 1971 |
Levodopa in Parkinsonism: potentiation of central effects with a peripheral inhibitor.
Topics: Administration, Oral; Adult; Biotransformation; Brain; Carbon Monoxide Poisoning; Cerebral Palsy; Child; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Female; Humans; Hydrazines; Male; Methyldopa; Neurologic Examination; Neuromuscular Diseases; Parkinson Disease; Phenylacetates; Pyridoxine; Time Factors | 1972 |
Plasma concentration of levodopa in Parkinsonism before and after inhibition of peripheral decarboxylase.
Topics: Carboxy-Lyases; Clinical Trials as Topic; Dihydroxyphenylalanine; Humans; Hydrazines; Male; Methyldopa; Movement Disorders; Parkinson Disease | 1972 |
3-O-Methyldopa, L-dopa, and trihexyphenidyl in the treatment of Parkinson's disease.
Topics: Aged; Clinical Trials as Topic; Dihydroxyphenylalanine; Disability Evaluation; Drug Interactions; Female; Humans; Male; Methyldopa; Middle Aged; Parkinson Disease; Time Factors; Trihexyphenidyl | 1973 |
Interaction between levodopa and methyldopa.
Topics: Blood Pressure; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Synergism; Humans; Methyldopa; Parkinson Disease | 1973 |
Evaluation of alpha methyl dopa and alpha methyl dopa hydrazine with L-dopa therapy.
Topics: Adult; Aged; Carbidopa; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrazines; Methyldopa; Middle Aged; Parkinson Disease | 1974 |
Idiopathic Parkinsonism treated with an extracerebral decarboxylase inhibitor in combination with levodopa.
Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Synergism; Female; Humans; Hydrazines; Male; Methyldopa; Middle Aged; Nausea; Parkinson Disease; Vomiting | 1971 |
Action of L- -methyldopa-hydrazine on the blood pressure of patients receiving levodopa.
Topics: Adult; Aged; Blood Pressure; Dihydroxyphenylalanine; Dopamine; Female; Humans; Hydrazines; Hypotension; Male; Methyldopa; Middle Aged; Parkinson Disease; Pulse | 1972 |
Methyldopahydrazine as an adjunct to L-dopa therapy in parkinsonism.
Topics: Adolescent; Adult; Aged; Blood Pressure; Brain; Child; Dihydroxyphenylalanine; Dopamine; Evaluation Studies as Topic; Female; Gastrointestinal Diseases; Heart; Humans; Hydrazines; Hydroxyindoleacetic Acid; Male; Methyldopa; Middle Aged; Motor Skills; Parkinson Disease; Phenylacetates; Serotonin | 1972 |
263 other study(ies) available for dihydroxyphenylalanine and methyldopa
| Article | Year |
|---|---|
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
The neurochemistry of Parkinson's disease: effect of L-dopa therapy.
Topics: Aged; Brain; Catechol O-Methyltransferase; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Female; Homovanillic Acid; Humans; Levodopa; Male; Methyldopa; Middle Aged; Monoamine Oxidase; Parkinson Disease; Tyrosine 3-Monooxygenase | 1975 |
Demethylation in erythrocytes: a reaction involving hemoglobin.
Topics: Animals; Catecholamines; Dihydroxyphenylalanine; Erythrocytes; Hemoglobins; Humans; Hydrogen-Ion Concentration; Methylation; Methyldopa; Oxidoreductases; Oxidoreductases, O-Demethylating; Pyridoxal Phosphate; Rats; Species Specificity; Tetrahydrofolates | 1978 |
Highly sensitive assay for tyrosine hydroxylase activity by high-performance liquid chromatography.
Topics: Animals; Brain Stem; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Humans; Methyldopa; Putamen; Rats; Tyrosine 3-Monooxygenase | 1979 |
[Effects of precursors and metabolites of catecholamines on motricity of isolated rat duodenum. Particular reference to dopamine].
Topics: Animals; Catecholamines; Dihydroxyphenylalanine; Dopamine; Duodenum; Epinephrine; Gastrointestinal Motility; Homovanillic Acid; Male; Metanephrine; Methyldopa; Norepinephrine; Normetanephrine; Rats | 1979 |
Inhibition of histidine, decarboxylation in vivo by 2-hydroxy-5-carbomethoxybenzyloxyamine, a new, potent inhibitor of histidine decarboxylase.
Topics: Animals; Carbon Dioxide; Carboxy-Lyases; Dihydroxyphenylalanine; Glutamates; Histidine; Histidine Ammonia-Lyase; Hydroxylamines; Liver; Male; Methyldopa; Phenols; Pyruvates; Rats; Stomach; Transaminases; Urocanate Hydratase | 1975 |
alpha-difluoromethyl DOPA, a new enzyme-activated irreversible inhibitor of aromatic L-amino acid decarboxylase.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Dihydroxyphenylalanine; Dopamine; In Vitro Techniques; Male; Methyldopa; Mice; Norepinephrine; Rats | 1978 |
Effect of a catechol-O-methyl transferase inhibitor, U-0521, with levodopa administration.
Topics: Animals; Behavior, Animal; Brain; Catechol O-Methyltransferase Inhibitors; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Homovanillic Acid; Levodopa; Male; Methyldopa; Propiophenones; Rats; Time Factors | 1979 |
Brain tissue and plasma assay of L-DOPA and alpha-methyldopa metabolites by high performance liquid chromatography with electrochemical detection.
Topics: Animals; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Humans; Hypothalamus; Male; Methyldopa; Parkinson Disease; Rats | 1979 |
Chemical lonization mass spectrometric measurement of alpha-methyldopa and s-dopa metabolites in rat brain regions.
Topics: Animals; Brain; Brain Stem; Corpus Striatum; Deuterium; Dihydroxyphenylalanine; Hypothalamus; Isotope Labeling; Kinetics; Mass Spectrometry; Methyldopa; Norepinephrine; Organ Specificity; Rats | 1977 |
Effect of L-DOPA analogues in Sidman avoidance performance in mice.
Topics: Animals; Avoidance Learning; Benserazide; Brain; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Levodopa; Male; Methyldopa; Mice; Motor Activity; Norepinephrine; Serotonin | 1977 |
Gas-chromatographic resolution of the enantiomers of 3-(3,4-dihydroxyphenyl)alanine and its alpha-methyl analog.
Topics: Chromatography, Gas; Dihydroxyphenylalanine; Isomerism; Mass Spectrometry; Methyldopa | 1977 |
Detection of occult metastatic melanoma by urine chromatography.
Topics: Chromatography, Ion Exchange; Cysteinyldopa; Dihydroxyphenylalanine; Female; Humans; Male; Melanoma; Methyldopa; Neoplasm Metastasis | 1976 |
[Urinary excretion of 3,4-dihydroxyphenyl-alanine, 3-O-methyldopa, dopamine and homovanillic acid in man. Effects of an inhibitor of decarboxylase of aromatic amino acids (Benserazide) (author's transl)].
Topics: Adult; Benserazide; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Humans; Hydrazines; Male; Methyldopa; Phenylacetates; Time Factors | 1976 |
Homologs of dopa, alpha-methyldopa, and dopamine as potential cardiovascular drugs.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain; Brain Chemistry; Dihydroxyphenylalanine; Dogs; Dopamine; Dopamine beta-Hydroxylase; Drug Synergism; Kidney; Male; Methyldopa; Mice; Myocardium; Rats; Regional Blood Flow; Structure-Activity Relationship | 1975 |
Effects of stress and drugs on the catecholamine and pepsin concentrations in stomach wall of rat.
Topics: Animals; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Electric Stimulation; Gastric Mucosa; Histamine; Immobilization; Male; Methyldopa; Pepsin A; Pepsinogens; Rats; Reserpine; Serotonin; Stimulation, Chemical; Stress, Physiological | 1975 |
Potentiation of the central nervous system effects of DOPA by decarboxylase inhibition: possible direct role of this neuroamino acid in brain mechanisms.
Topics: Agonistic Behavior; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Brain; Depression, Chemical; Dihydroxyphenylalanine; Disulfides; Dopa Decarboxylase; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Evoked Potentials; Methyldopa; Methyltyrosines; Mice; Motor Activity; Pargyline; Phenethylamines; Piperazines; Rabbits; Reserpine; Somatosensory Cortex; Stimulation, Chemical; Sulfhydryl Compounds; Visual Cortex | 1975 |
The 4-o-methyl metabolites of catecholamines. Homo-iso-vanillic acid in rat urine and brain; urinary iso-vanyl compounds after intraperitoneal administration of dopamine and of dopamine precursors and derivatives.
Topics: Animals; Brain Chemistry; Catecholamines; Chromatography, Paper; Dihydroxyphenylalanine; Dopamine; Fasting; Female; Homovanillic Acid; Indicators and Reagents; Isomerism; Male; Methyldopa; Phenols; Phenylacetates; Rats | 1975 |
Intragranular starch: comparison of starch USP and modified cornstarch.
Topics: Acetaminophen; Ascorbic Acid; Biopharmaceutics; Cellulose; Chlorothiazide; Dihydroxyphenylalanine; Excipients; Hardness Tests; Kinetics; Methyldopa; Pressure; Probenecid; Solubility; Starch; Tablets | 1975 |
(18F) Fluoro-Dopa: a unique gamma emitting substrate for Dopa decarboxylase.
Topics: Animals; Brain; Carbon Radioisotopes; Dihydroxyphenylalanine; Dopa Decarboxylase; Fluorine; Gamma Rays; Kidney; Kinetics; Methyldopa; Pyridoxal Phosphate; Rabbits; Radioisotopes; Radionuclide Imaging; Swine | 1975 |
Synthesis of substituted DL-3(5-benzazolyl)alanines as dopa and alpha-methyldopa analogs and their effects on dopamine beta-hydroxylase, tyrosinase and diphenoloxidase.
Topics: Adrenal Glands; Animals; Basidiomycota; Benzimidazoles; Catechol Oxidase; Cattle; Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; Fabaceae; In Vitro Techniques; Methyldopa; Monophenol Monooxygenase; Phenylalanine; Plants, Medicinal | 1992 |
Regional brain kinetics of 6-fluoro-(beta-11C)-L-dopa and (beta-11C)-L-dopa following COMT inhibition. A study in vivo using positron emission tomography.
Topics: Animals; Benzophenones; Brain; Carbon Radioisotopes; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Corpus Striatum; Dihydroxyphenylalanine; Female; Half-Life; Macaca mulatta; Methyldopa; Nitrophenols; Tolcapone; Tomography, Emission-Computed | 1992 |
High-performance liquid chromatography with electrochemical detection for the determination of levodopa, catecholamines and their metabolites in rat brain dialysates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Catecholamines; Caudate Nucleus; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Epinephrine; Homovanillic Acid; Injections, Intraperitoneal; Levodopa; Male; Methyldopa; Norepinephrine; Rats; Rats, Inbred Strains; Substantia Nigra | 1992 |
Determination of free DOPA and 3-O-methyl-DOPA in human plasma by high-performance liquid chromatography with electrochemical detection.
Topics: Dihydroxyphenylalanine; Electrochemistry; Humans; Methyldopa; Ultrafiltration | 1991 |
Pharmacokinetics of L-dopa in patients with Parkinson's disease.
Topics: Biotransformation; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Disability Evaluation; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Humans; Kinetics; Levodopa; Methyldopa; Parkinson Disease; Receptors, Dopamine; Receptors, Dopamine D2; Tiapamil Hydrochloride | 1987 |
Inhibition of monoamine oxidase by 3,4-dihydroxyphenyl L-alanine and its analogues.
Topics: Dihydroxyphenylalanine; Droxidopa; Humans; In Vitro Techniques; Kynuramine; Levodopa; Methyldopa; Mitochondria; Mitochondria, Liver; Monoamine Oxidase Inhibitors; Placenta; Stereoisomerism; Structure-Activity Relationship | 1987 |
Species-dependent differences in recovery of 3,4-dihydroxybenzylamine in assays of plasma catecholamines.
Topics: Animals; Blood Proteins; Catecholamines; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Electrochemistry; Goats; Humans; Indicators and Reagents; Methyldopa; Species Specificity | 1988 |
Studies on rheomelanins. I. The formation of rheomelanins in human blood plasma from catecholamines, from L-dopa and from some of their derivatives.
Topics: Chromatography, Paper; Dihydroxyphenylalanine; Dopamine; Epinephrine; Humans; Melanins; Methyldopa; Norepinephrine; Psychotic Disorders; Spectrophotometry; Stereoisomerism | 1970 |
Inhibition of drug metabolism by levodopa in combination with a dopa-decarboxylase inhibitor.
Topics: Administration, Oral; Adult; Aged; Antipyrine; Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Drug Synergism; Humans; Hydrazines; Methyldopa; Middle Aged; Pharmaceutical Preparations; Time | 1971 |
[Effect of administration of amino acids, especially of L-DOPA and -methyldopa, on the composition of cerebrospinal fluid in extrapyramidal syndromes. 3. Alterations of cerebrospinal fluid in patients with Huntington's chorea after -methyldopa or L-DOPA
Topics: Adult; Aged; Alanine Transaminase; Asparagine; Aspartic Acid; Child; Dihydroxyphenylalanine; Female; Glutamates; Glutamine; Glycine; Humans; Huntington Disease; Male; Methyldopa; Middle Aged; Phenylalanine; Pyruvates; Threonine | 1973 |
Incorporation of L-dopa, L-alpha-methyldopa and DL-isoproterenol into guinea pig hair.
Topics: Animals; Carbon Radioisotopes; Dihydroxyphenylalanine; Guinea Pigs; Hair; Isoproterenol; Melanins; Melanocytes; Methyldopa; Skin; Time Factors; Tritium | 1974 |
The anticonvulsant effect of carbonic anhydrase inhibitors in mice--a noradrenergic mechanism of action.
Topics: Acetazolamide; Amino Acids; Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Carboxy-Lyases; Dichlorphenamide; Dihydroxyphenylalanine; Disulfiram; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Electroshock; Female; Hydrazines; Methazolamide; Methyldopa; Mice; Monoamine Oxidase Inhibitors; Picolinic Acids; Reserpine | 1973 |
Dopa decarboxylase in medullary carcinoma of the thyroid.
Topics: Adrenal Gland Neoplasms; Amine Oxidase (Copper-Containing); Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Carcinoma; Cresols; Dihydroxyphenylalanine; Dopa Decarboxylase; Histamine; Histidine; Humans; Hydrazines; Hydroxylamines; Methyldopa; Methylhistidines; Norepinephrine; Pheochromocytoma; Serotonin; Thyroid Gland; Thyroid Neoplasms; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase | 1973 |
On the mechanism of L-dopa-induced postural hypotension in the cat.
Topics: Adrenergic alpha-Antagonists; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Pressure; Carotid Arteries; Cats; Chemoreceptor Cells; Dihydroxyphenylalanine; Dogs; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Ganglia, Autonomic; Ganglionic Blockers; Intestines; Kidney; Male; Methyldopa; Posture; Pressoreceptors; Rats; Spinal Cord | 1973 |
Comparison of centrally mediated hypotensive action of methyldopa and DOPA in cats.
Topics: Adrenergic alpha-Antagonists; Amino Acids; Animals; Antihypertensive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benzoates; Blood Pressure; Carbidopa; Cats; Cerebral Ventricles; Dihydroxyphenylalanine; Disulfides; Dopamine beta-Hydroxylase; Female; Imidazoles; Male; Methyldopa; Perfusion; Phentolamine; Pyrimidines; Spiro Compounds; Sulfhydryl Compounds; Time Factors | 1973 |
The problem of postural hypotension.
Topics: Adrenergic beta-Antagonists; Aged; Dihydroxyphenylalanine; Diuretics; Female; Guanethidine; Humans; Hypotension, Orthostatic; Male; Methyldopa; Nitrites; Tranquilizing Agents | 1974 |
A new biosynthetic pathway to catecholamines via m-tyrosine.
Topics: Adrenal Glands; Animals; Benzyl Compounds; Brain; Carbon Radioisotopes; Catalysis; Catecholamines; Dihydroxyphenylalanine; Hydroxylation; In Vitro Techniques; Iron; Liver; Methyldopa; Methyltyrosines; Mice; Monoiodotyrosine; NADP; Phenylalanine; Phenylalanine Hydroxylase; Phosphates; Pterins; Rats; Structure-Activity Relationship; Tyrosine | 1974 |
The effect of L-DOPA on brain polysomes and protein synthesis: probable mediation by intracellular dopamine.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carbon Radioisotopes; Decarboxylation; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Enzyme Inhibitors; Hydrazines; Leucine; Levodopa; Lysine; Male; Methyldopa; Nerve Tissue Proteins; Norepinephrine; Polyribosomes; Rats; S-Adenosylmethionine; Time Factors | 1974 |
DOPA in Parkinson's disease.
Topics: Animals; Dihydroxyphenylalanine; Humans; Methyldopa; Parkinson Disease; Parkinson Disease, Postencephalitic | 1969 |
Dopa in Parkinson's disease.
Topics: Dihydroxyphenylalanine; Humans; Methyldopa; Parkinson Disease; Tranquilizing Agents | 1969 |
[Methyldopa and levodopa].
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Humans; Hypertension; Methyldopa; Parkinson Disease | 1974 |
[Specific therapy of extrapyramidal-motor syndromes].
Topics: Analgesics; Athetosis; Chorea; Datura stramonium; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Extrapyramidal Tracts; Female; Humans; Huntington Disease; Methyldopa; Movement Disorders; Myoclonus; Parasympatholytics; Parkinson Disease; Parkinson Disease, Postencephalitic; Phenothiazines; Physical Therapy Modalities; Phytotherapy; Plants, Medicinal; Plants, Toxic; Pregnancy; Pyridoxine; Reserpine; Scopolamine; Stereotaxic Techniques; Tranquilizing Agents | 1969 |
Central decarboxylation and uptake of L-DOPA.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Capillaries; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Hydrazines; Male; Methyldopa; Nerve Endings; Rats; Receptors, Adrenergic; Spinal Cord | 1972 |
Comparison of behavioral and cardiovascular effects of L-DOPA and 5-HTP in conscious dogs.
Topics: Animals; Behavior, Animal; Blood Pressure; Cardiovascular System; Dihydroxyphenylalanine; Dogs; Female; Fenclonine; Haloperidol; Hydrazines; Injections, Intramuscular; Injections, Intraperitoneal; Injections, Intravenous; Male; Methyldopa; Methysergide; Serotonin | 1972 |
[Monoamines and choreic syndromes].
Topics: Amines; Butyrophenones; Chorea; Diazepam; Dihydroxyphenylalanine; Dopamine; Ganglia; Globus Pallidus; Homovanillic Acid; Humans; Huntington Disease; Mental Disorders; Methyldopa; Methyltyrosines; Models, Neurological; Movement Disorders; Phenothiazines; Physostigmine; Reserpine; Thalamus; Tranquilizing Agents; Tyrosine | 1972 |
Orthohydroxyhippuric (salicyluric) acid--its physiologic and clinical significance.
Topics: Anemia; Animals; Cattle; Dihydroxyphenylalanine; Dogs; Down Syndrome; Fever; Glycine; Humans; Hypertension; Liver Diseases; Methyldopa; Mitochondria, Liver; Pheochromocytoma; Rats; Salicylates; Swine; Uremia; Wounds and Injuries | 1974 |
[Brain amines and apomorphine-induced intraspecific aggressive behavior in the rat (author's transl)].
Topics: 5-Hydroxytryptophan; Aggression; Animals; Apomorphine; Biogenic Amines; Brain; Brain Chemistry; Clonidine; Dihydroxyphenylalanine; Dioxoles; Disulfides; Fenclonine; Humans; Hydrazines; Hydroxybutyrates; Imidazoles; Iproniazid; Male; Methyldopa; Methyltyrosines; Phenoxybenzamine; Piperazines; Rats; Reserpine; Serotonin; Thiocarbamates; Time Factors | 1974 |
Functional aspects of 5-hydroxytryptamine turnover in the central nervous system.
Topics: 5-Hydroxytryptophan; Acetamides; Animals; Antidepressive Agents; Brain; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Fenclonine; Humans; Hydrazines; Imipramine; Male; Methyldopa; Motor Activity; Nialamide; Receptors, Drug; Reserpine; Serotonin; Stimulation, Chemical; Stress, Psychological; Tryptophan; Tyrosine | 1974 |
Effect of false transmitters on norepinephrine synthesis.
Topics: Animals; Carbon Isotopes; Chlorisondamine; Dihydroxyphenylalanine; Dopamine; Heart; In Vitro Techniques; Metaraminol; Methyldopa; Mixed Function Oxygenases; Myocardium; Norepinephrine; Octopamine; Pempidine; Rats; Synaptic Transmission; Time Factors; Tritium; Tyrosine | 1969 |
Modification of the cardiovascular effects of L-dopa in anesthetized dogs by inhibitors of enzymes involved in catecholamine metabolism.
Topics: Angiotensin II; Animals; Blood Pressure; Bradycardia; Carboxy-Lyases; Cresols; Dihydroxyphenylalanine; Dogs; Dopamine; Female; Heart Rate; Hydrazines; Hypertension; Hypotension; Male; Methyldopa; Monoamine Oxidase Inhibitors; Norepinephrine; Tachycardia; Thiocarbamates | 1971 |
Structural determinants of catecholamine action on in vitro insulin release.
Topics: Animals; Butyrates; Catecholamines; Cricetinae; Cyclic AMP; Dihydroxyphenylalanine; Dopamine; Epinephrine; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Isoproterenol; Methyldopa; Norepinephrine; Pancreas; Phenethylamines; Phentolamine; Phenylacetates; Phenylalanine; Phenylephrine; Structure-Activity Relationship; Tyramine; Tyrosine | 1971 |
A neuropsychopharmacological comparison of d-amphetamine, L-dopa and cocaine.
Topics: Animals; Behavior, Animal; Cats; Cocaine; Cortical Synchronization; Dextroamphetamine; Dihydroxyphenylalanine; Electroencephalography; Female; Hair; Humans; Hydrazines; Male; Methyldopa; Paranoid Disorders; Parkinson Disease; Phenethylamines; Reticular Formation; Salivation; Sleep, REM; Stereoisomerism | 1971 |
A reliable and simple method for simultaneous determination of DOPA and 3-O-methyldopa in plasma and brain.
Topics: Antiparkinson Agents; Brain Chemistry; Carbon Isotopes; Chromatography, Ion Exchange; Cold Temperature; Dihydroxyphenylalanine; Edetic Acid; Epinephrine; Ferricyanides; Humans; Hydrazines; Hydrogen-Ion Concentration; Iodine; Methods; Methyldopa; Norepinephrine; Oxidation-Reduction; Parkinson Disease; Perchlorates; Periodic Acid; Spectrometry, Fluorescence | 1972 |
Catechol O-methyltransferase. IV. Factors affecting m- and p-methylation of substituted catechols.
Topics: Aluminum; Animals; Catechol O-Methyltransferase; Catechols; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Thin Layer; Dihydroxyphenylalanine; Dopamine; Epinephrine; Hydrogen-Ion Concentration; Hydrolysis; Lithium; Liver; Methylation; Methyldopa; Methyltransferases; Norepinephrine; Normetanephrine; Oxidation-Reduction; Periodic Acid; Rats; Stereoisomerism; Structure-Activity Relationship | 1972 |
Complete analysis of levodopa capsules and tablets by GLC.
Topics: Amino Acids; Capsules; Chemical Phenomena; Chemistry; Chromatography, Gas; Dihydroxyphenylalanine; Drug Stability; Methods; Methyldopa; Silicon Dioxide; Tablets; Time Factors | 1973 |
Drug-induced changes in monoamine levels in the sympathetic adrenergic ganglion cells and terminals. A histochemical study.
Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Dihydroxyphenylalanine; Dopamine; Ephedrine; Ganglia, Autonomic; Hydrazines; Methyldopa; Microscopy, Fluorescence; Nerve Endings; Neurochemistry; Nialamide; Pargyline; Rats; Reserpine; Tranylcypromine; Tyrosine | 1965 |
Impairment of sympathetic nerve responses by dopa, dopamine and their alpha-methyl analogues.
Topics: Animals; Cats; Dihydroxyphenylalanine; Dopamine; Epinephrine; Methyldopa; Nictitating Membrane; Norepinephrine; Pargyline; Sympathetic Nervous System; Sympathomimetics | 1965 |
The interaction of pyridoxal phosphate with tyrosine analogs.
Topics: Animals; Dihydroxyphenylalanine; Dopamine; Enzymes; Epinephrine; In Vitro Techniques; Liver; Male; Methyldopa; Methyltyrosines; Normetanephrine; Octopamine; Phenylalanine; Pyridoxal Phosphate; Rats; Transaminases; Tyramine; Tyrosine; Tyrosine Transaminase; Ultraviolet Rays | 1966 |
Histidine decarboxylase in the stomach of the rat.
Topics: Animals; Benzene; Carbon Isotopes; Carboxy-Lyases; Dihydroxyphenylalanine; Gastric Mucosa; Histamine; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Methyldopa; Pylorus; Rats; Serotonin; Starvation; Stomach; Temperature | 1967 |
Chemical, electron microscopic and physiological observations on the role of catecholamines in the carotid body.
Topics: Adrenalectomy; Animals; Carotid Body; Catecholamines; Cats; Chemoreceptor Cells; Dihydroxyphenylalanine; Dopamine; Epinephrine; In Vitro Techniques; Injections, Intravenous; Isoproterenol; Methyldopa; Microscopy, Electron; Norepinephrine; Peripheral Nerves; Pressoreceptors; Reserpine; Sympathectomy; Tyramine | 1969 |
Effect of various decarboxylase inhibitors on the cerebral metabolism of dihydroxyphenylalanine.
Topics: Amino Acids; Animals; Brain; Carbon Isotopes; Carboxy-Lyases; Catecholamines; Dihydroxyphenylalanine; Methyldopa; Rats | 1969 |
The effect of various agents on the pressor response to dopa in the anesthetized dog.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Arteries; Blood Pressure; Bretylium Compounds; Cocaine; Cresols; Dihydroxyphenylalanine; Dogs; Dopamine Antagonists; Female; Guanethidine; Hydrazines; Male; Methyldopa; Norepinephrine; Oxidoreductases; Stimulation, Chemical; Thiocarbamates | 1969 |
The effect of reserpine on the pressor responses to angiotensin in the conscious cat.
Topics: Angiotensin II; Animals; Blood Pressure; Carbamates; Cats; Dihydroxyphenylalanine; Methyldopa; Norepinephrine; Quaternary Ammonium Compounds; Reserpine; Tetrabenazine; Tranylcypromine; Tyramine | 1970 |
Further studies on the mechanism of the central hypotensive effect of L-dopa, DL-m-tyrosine and L-alpha-methyldopa.
Topics: Animals; Arteries; Blood Pressure; Brain; Brain Chemistry; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Male; Methyldopa; Norepinephrine; Propionates; Rats; Tyrosine | 1971 |
4,4,6-trimethyl-3,4-dihydropyrimidine-2-thiol, an effective inhibitor of dopamine-beta-hydroxylation in vivo.
Topics: Acetaldehyde; Amino Alcohols; Animals; Benzyl Compounds; Blood Pressure; Brain Chemistry; Carbon Isotopes; Cattle; Dihydroxyphenylalanine; Disulfiram; Dopamine; Ethanol; Ethylamines; Female; Heart; Hydrazines; Iodine; Male; Metaraminol; Methyldopa; Methyltyrosines; Mice; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Normetanephrine; Propylthiouracil; Pyrimidines; Rats; Reserpine; Stereoisomerism; Sulfhydryl Compounds; Thyroid Gland; Tyramine | 1971 |
Evidence for a centrally mediated hypotensive effect of L-dopa in the rat.
Topics: Animals; Blood Pressure; Central Nervous System; Depression, Chemical; Dihydroxyphenylalanine; Disulfides; Disulfiram; Dopamine beta-Hydroxylase; Hydrazines; Imidazoles; Male; Methyldopa; Rats; Rats, Inbred Strains | 1970 |
Catecholamines and the hydroxylation of tyrosine in synaptosomes isolated from rat brain.
Topics: Animals; Autoradiography; Brain; Catecholamines; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Dopamine; Male; Methyldopa; Methyltyrosines; Mixed Function Oxygenases; Monoiodotyrosine; Norepinephrine; Normetanephrine; Octopamine; Phenethylamines; Rats; Serotonin; Synaptic Vesicles; Time Factors; Tritium; Tyramine; Tyrosine; Tyrosine 3-Monooxygenase | 1971 |
Inhibition of catechol-O-methyl transferase by L-dopa and decarboxylase inhibitors.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Catechols; Dihydroxyphenylalanine; Hydrazines; Liver; Methyldopa; Methyltransferases; Norepinephrine; Normetanephrine; Propionates; Pyrogallol; Rats; Tritium | 1972 |
Aggression in rats treated with dopa and 6-hydroxydopamine.
Topics: Adrenal Glands; Aggression; Animals; Apomorphine; Dihydroxyphenylalanine; Humans; Hydrazines; Methyldopa; Phenethylamines; Propionates; Rats; Thiocarbamates; Tyrosine 3-Monooxygenase | 1972 |
Dopamine: mediator of brain polysome disaggregation after L-dopa.
Topics: Animals; Benzyl Compounds; Brain; Brain Chemistry; Carboxy-Lyases; Dihydroxyphenylalanine; Dopamine; Hydrazines; Injections, Intraperitoneal; Male; Methyldopa; Norepinephrine; Rats; Rats, Inbred Strains; Ribosomes; S-Adenosylmethionine; Serine | 1972 |
On the localization of the hypotensive effect of L-dopa.
Topics: Animals; Arteries; Blood Pressure; Brain Chemistry; Cordotomy; Decerebrate State; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Hydrazines; Male; Methyldopa; Norepinephrine; Propionates; Rats | 1972 |
Erythrocyte antibodies in autoimmune hemolytic anemia.
Topics: Anemia, Hemolytic, Autoimmune; Antibody Specificity; Autoantibodies; Bilirubin; Bone Marrow Examination; Cold Temperature; Complement Fixation Tests; Coombs Test; Dihydroxyphenylalanine; Erythrocytes; Hemagglutination Tests; Humans; Immunoglobulin Fc Fragments; Immunoglobulin G; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Macrophages; Methyldopa; Penicillins; Phagocytosis; Spleen | 1974 |
Absorption, metabolism and distribution of (14C)-O-methyldopa and (14C)-L-dopa after oral administration to rats.
Topics: Administration, Oral; Animals; Brain Chemistry; Carbon Radioisotopes; Dihydroxyphenylalanine; Intestines; Male; Methyldopa; Phenylacetates; Rats; Stomach | 1974 |
Dopa, 3-O-methyldopa, and metabolites in urine during oral L-3-O-methyldopa therapy.
Topics: Administration, Oral; Autoanalysis; Catecholamines; Dealkylation; Decarboxylation; Dihydroxyphenylalanine; Fluorometry; Homovanillic Acid; Humans; Lactates; Male; Methoxyhydroxyphenylglycol; Methyldopa; Parkinson Disease; Vanilmandelic Acid | 1974 |
Reinitiation of estrous cycles in light-induced constant estrous female rats by drugs.
Topics: Amphetamine; Amphetamines; Animals; Autonomic Agents; Brain; Catecholamines; Dihydroxyphenylalanine; Estrus; Female; Iproniazid; Light; Luteinizing Hormone; Methyldopa; Ovulation; Periodicity; Pregnancy; Rats; Reserpine; Serotonin; Tyrosine | 1974 |
The relevance of the neurophysiological concepts of excitation and inhibition to clinical psychiatry.
Topics: Acoustic Stimulation; Adolescent; Adult; Aged; Alcohol Amnestic Disorder; Anxiety; Arousal; Dihydroxyphenylalanine; Electroencephalography; Galvanic Skin Response; Habituation, Psychophysiologic; Humans; Hysteria; Mental Disorders; Methyldopa; Middle Aged; Obsessive-Compulsive Disorder; Parkinson Disease; Personality Inventory; Schizophrenia; Schizophrenia, Paranoid | 1973 |
Inhibition of dopa decarboxylation by RO4-4602, MK 485 and MK 486 in human liver homogenates.
Topics: 5-Hydroxytryptophan; Aromatic Amino Acid Decarboxylase Inhibitors; Benzyl Compounds; Binding Sites; Carbon Isotopes; Copper; Decarboxylation; Depression, Chemical; Dihydroxyphenylalanine; Humans; Hydrazines; In Vitro Techniques; Kinetics; Liver; Methyldopa; Serine | 1972 |
Concentration of histamine in different parts of the brain and hypophysis of rabbit: effect of treatment with histidine, certain other amino acids and histamine.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Biological Assay; Brain Chemistry; Caudate Nucleus; Cerebellum; Cerebral Cortex; Dihydroxyphenylalanine; Hippocampus; Histamine; Histidine; Hypothalamus; Injections, Intravenous; Male; Methyldopa; Pituitary Gland; Rabbits; Thalamus | 1973 |
[Influence of various neurotropic drugs (L-dopa and alphamethyl-dopa) in Cushing's disease].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Circadian Rhythm; Corticotropin-Releasing Hormone; Cushing Syndrome; Dexamethasone; Dihydroxyphenylalanine; Drug Evaluation; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Methyldopa; Stimulation, Chemical; Vasopressins | 1974 |
Inhibition of norepinephrine biosynthesis by -methyl amino acids in the guinea-pig vas deferens.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbon Isotopes; Dihydroxyphenylalanine; Dopamine; Guinea Pigs; Hypogastric Plexus; In Vitro Techniques; Male; Methylamines; Methyldopa; Methyltyrosines; Norepinephrine; Octopamine; Tritium; Tyramine; Tyrosine; Vas Deferens | 1972 |
The effect of L-dopa on insulin release by isolated pancreatic islets of the rat.
Topics: Animals; Dihydroxyphenylalanine; Drug Synergism; Insulin; Insulin Secretion; Islets of Langerhans; Male; Methyldopa; Organ Culture Techniques; Radioimmunoassay; Rats; Species Specificity; Structure-Activity Relationship; Tyrosine | 1973 |
The action of alpha-methyldopa in the cerveau isole preparation.
Topics: Animals; Blood Pressure; Brain; Brain Stem; Cats; Cerebellum; Cerebral Cortex; Cortical Synchronization; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Electroencephalography; Gallamine Triethiodide; Infusions, Parenteral; Male; Methyldopa; Optical Rotation; Phenoxybenzamine; Propranolol; Reserpine; Stereoisomerism; Stereotaxic Techniques; Structure-Activity Relationship; Time Factors | 1974 |
Modification by drugs of the secretagogue effect of dopamine on the pancrease.
Topics: Animals; Apomorphine; Catecholamines; Cholecystokinin; Dihydroxyphenylalanine; Dogs; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Female; Hydroxydopamines; Male; Methyldopa; Norepinephrine; Octopamine; Pancreas; Perfusion; Reserpine; Secretin; Spectrometry, Fluorescence; Stimulation, Chemical; Time Factors | 1974 |
Tremor and involuntary movements in monkeys: effect of L-dopa and of a dopamine receptor stimulating agent.
Topics: 5-Hydroxytryptophan; Animals; Benzyl Compounds; Dihydroxyphenylalanine; Dioxoles; Drug Interactions; Electroencephalography; Haloperidol; Haplorhini; Humans; Hydrazines; Hyperkinesis; Injections, Intraperitoneal; Methyldopa; Methyltyrosines; Picolinic Acids; Piperazines; Pyrimidines; Tremor | 1973 |
Effects of peripheral aromatic L-amino acids decarboxylase inhibitor on L-(2- 14 C)-3,4-dihydroxyphenylalanine metabolism in man.
Topics: Amino Acids; Carbon Isotopes; Carboxy-Lyases; Catecholamines; Dihydroxyphenylalanine; Dopamine; Hydrazines; Methyldopa; Phenols; Phenylacetates; Time Factors | 1972 |
The action of L(-)-dopa on baroreflexes in Parkinsonism.
Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Dihydroxyphenylalanine; Female; Humans; Hydrazines; Male; Methyldopa; Middle Aged; Parkinson Disease; Posture; Pressoreceptors; Reflex; Valsalva Maneuver | 1972 |
Isolation of metabolites of L-dopa--a possible source of error.
Topics: Amino Acids; Animals; Bile; Carbon Isotopes; Catecholamines; Chromatography, Ion Exchange; Chromatography, Paper; Dihydroxyphenylalanine; Dopamine; Fluorometry; Glucuronates; In Vitro Techniques; Liver; Methods; Methyldopa; Perfusion; Proteins; Rats | 1972 |
Effects of L-DOPA and L-3-O-methyl-DOPA on uptake of (3H)L-methionine by synaptosomes.
Topics: Animals; Binding, Competitive; Biological Transport, Active; Brain; Centrifugation; Cocaine; Depression, Chemical; Desipramine; Dihydroxyphenylalanine; Dinitrophenols; In Vitro Techniques; Kinetics; Male; Methionine; Methyldopa; Mitochondria; Nerve Endings; Ouabain; Rats; Sodium; Synaptosomes; Temperature; Time Factors; Tritium | 1972 |
L-dopa in Parkinsonism. A possible mechanism of action.
Topics: Amines; Animals; Basal Ganglia; Brain; Carbon Isotopes; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Frontal Lobe; Hydroxydopamines; Methyldopa; Norepinephrine; Parkinson Disease; Rats; Serotonin; Tritium; Tyrosine; Urea | 1972 |
Prescription change: methyldopa for levodopa.
Topics: Dihydroxyphenylalanine; Drug Prescriptions; Humans; Medication Errors; Methyldopa | 1972 |
Modification of levodopa effect by systemic decarboxylase inhibition.
Topics: Arrhythmias, Cardiac; Carboxy-Lyases; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Electrocardiography; Humans; Hydrazines; Methyldopa; Parkinson Disease | 1973 |
Effects of L-dopa and methyldopa on growth of mammary cancers in rats.
Topics: Animals; Benz(a)Anthracenes; Dihydroxyphenylalanine; Female; Injections, Subcutaneous; Mammary Neoplasms, Experimental; Methyldopa; Rats; Time Factors | 1973 |
[Stability and dissociation constants of L-dopa and alpha-L-methyldopa].
Topics: Dihydroxyphenylalanine; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Methyldopa; Oxidation-Reduction | 1973 |
Action of levodopa on the blood pressure of conscious rabbits.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Dihydroxyphenylalanine; Hydrazines; Iproniazid; Methyldopa; Rabbits | 1973 |
A therapeutic paradox? Combined treatment of Parkinson's disease with levodopa and methyldopa.
Topics: Dihydroxyphenylalanine; Drug Synergism; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Male; Methyldopa; Middle Aged; Muscle Rigidity; Parkinson Disease; Tremor | 1973 |
[Hypertension: 3 H-catecholamine metabolism in the adrenal glands and brain and tissue metabolism of 3 3 H-DOPA during reserpine, alpha-methyl DOPA and ST-155 administration in spontaneously hypertensive rats].
Topics: Adrenal Glands; Animals; Blood Pressure; Body Weight; Brain; Catecholamines; Clonidine; Dihydroxyphenylalanine; Dopamine; Female; Hypertension; Male; Methyldopa; Norepinephrine; Organ Size; Rats; Reserpine; Tritium | 1973 |
[Treatment of Parkinson's syndrome with L-dopa and its methylated derivatives: 3-OMD and 4-OMD associated with a decarboxylase inhibitor. Clinical and biochemical study].
Topics: Aged; Benserazide; Carboxy-Lyases; Depression; Dihydroxyphenylalanine; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrazines; Methyldopa; Middle Aged; Paralysis; Parkinson Disease; Sleep Wake Disorders; Time Factors | 1973 |
A comparative study on the ionization of catechol amines in aqueous solutions.
Topics: Boric Acids; Catecholamines; Dihydroxyphenylalanine; Dopamine; Isoproterenol; Methyldopa; Potassium Chloride; Potentiometry | 1973 |
Chapter 29. Anti-norepinephrine therapy against traumatic hemorrhagic necrosis of the spinal cord: preliminary report.
Topics: Animals; Bretylium Compounds; Cats; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Guanethidine; Hemorrhage; Hydroxydopamines; Methyldopa; Necrosis; Norepinephrine; Phenoxybenzamine; Reserpine; Spinal Cord; Spinal Cord Injuries; Sympatholytics | 1973 |
Reserpine rigidity and adrenergic neurones.
Topics: Animals; Dihydroxyphenylalanine; Iproniazid; Male; Methyldopa; Methyltyrosines; Monoamine Oxidase Inhibitors; Neurons; Norepinephrine; Rats; Reserpine; Serotonin; Sympathetic Nervous System; Tetrabenazine; Time Factors; Tranylcypromine; Vas Deferens | 1973 |
Saligenin analogs of l-DOPA and dl-alpha-methyl-DOPA.
Topics: Animals; Antiparkinson Agents; Blood Pressure; Desoxycorticosterone; Dihydroxyphenylalanine; Dopa Decarboxylase; Guinea Pigs; Haloperidol; Kidney; Methanol; Methyldopa; Methyltyrosines; Mice; Myocardium; Norepinephrine; Rats; Tyrosine | 1974 |
Regional distribution of catecholamines in rat brain after L-3-O-methyldopa and L-dopa.
Topics: Aluminum; Animals; Brain; Carbon Radioisotopes; Cerebellum; Cerebral Cortex; Chromatography, Ion Exchange; Chromatography, Paper; Corpus Striatum; Diencephalon; Dihydroxyphenylalanine; Dopamine; Female; Hypothalamus; Male; Medulla Oblongata; Mesencephalon; Methyldopa; Norepinephrine; Organ Specificity; Pons; Rats | 1974 |
Epinephrine binding to rat adipocytes and their subcellular fractions.
Topics: Adipose Tissue; Animals; Binding Sites; Cell Membrane; Dihydroxyphenylalanine; Epinephrine; Isoproterenol; Liver; Methyldopa; Microsomes; Mitochondria; Mitochondria, Liver; Phentolamine; Propranolol; Rats; Tritium; Tyrosine | 1974 |
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi.
Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Methyldopa; Mice; Movement Disorders; Parkinson Disease; Phenoxybenzamine; Pimozide; Reserpine | 1974 |
3-O-methyl metabolites of catecholamines: automated fluorometric assay and their plasma levels in patients receiving levodopa and carbidopa.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Autoanalysis; Blood-Brain Barrier; Brain Chemistry; Carbidopa; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Dopamine; Evaluation Studies as Topic; Homovanillic Acid; Humans; Methods; Methyldopa; Microchemistry; Phenylacetates; Spectrometry, Fluorescence; Time Factors | 1974 |
Analysis of urinary catecholamines: an improved auto-analyzer fluorescence method.
Topics: Autoanalysis; Dihydroxyphenylalanine; Drug Stability; Epinephrine; Evaluation Studies as Topic; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Indoles; Mathematics; Methods; Methyldopa; Microchemistry; Norepinephrine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors | 1974 |
Ergometry in the clinical evaluation of Parkinsonism.
Topics: Allied Health Personnel; Circadian Rhythm; Computers; Dietary Proteins; Dihydroxyphenylalanine; Hand; Humans; Mathematics; Methods; Methyldopa; Neurologic Examination; Parkinson Disease; Pressure; Time Factors; Work | 1974 |
Automated radiometric assays of enzymatic and nonenzymatic oxidation of DOPA in vitro.
Topics: Animals; Automation; Bicarbonates; Biological Assay; Carbon Dioxide; Carbon Radioisotopes; Decarboxylation; Dihydroxyphenylalanine; Dopa Decarboxylase; In Vitro Techniques; Liver; Methyldopa; Nitrogen; Oxidation-Reduction; Oxygen; Radiometry; Rats | 1974 |
"On-off" phenomenon with levodopa therapy in Parkinsonism. Clinical and pharmacologic correlations and the effect of intramuscular pyridoxine.
Topics: Adult; Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hydrazines; Injections, Intramuscular; Male; Methyldopa; Middle Aged; Movement Disorders; Parkinson Disease; Pyridoxine | 1974 |
The fluorometric assay of catecholamines and related compounds: improvements and extensions to the hydroxyindole technique.
Topics: Animals; Brain Chemistry; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Fluorometry; Hydrogen-Ion Concentration; Indoles; Iodine; Methyldopa; Methyltyrosines; Norepinephrine; Normetanephrine; Octopamine; Oxidation-Reduction; Phenethylamines; Rats; Tissue Extracts; Tyramine; Tyrosine | 1968 |
3-O-methyldopa, a new precursor of dopamine.
Topics: Animals; Brain; Brain Chemistry; Carbon Isotopes; Dealkylation; Dihydroxyphenylalanine; Dopamine; Female; Male; Methyldopa; Norepinephrine; Normetanephrine; Pargyline; Phenylacetates; Rats; Tyramine | 1971 |
Block of cerebral actions of L-dopa with methyl receptor substances.
Topics: Age Factors; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Hydrazines; Lethal Dose 50; Methyldopa; Mice; Phenylacetates; Postural Balance; Time Factors | 1971 |
Uptake of some catecholamines and their precursors into neurons of the rat ciliary ganglion.
Topics: Animals; Catecholamines; Cats; Ciliary Body; Dihydroxyphenylalanine; Dogs; Dopa Decarboxylase; Ganglia, Autonomic; Goats; Guinea Pigs; Haplorhini; Methyldopa; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Neurons; Nialamide; Rats; Reserpine | 1970 |
Drug-induced relief of experimental tremor in monkeys.
Topics: 5-Hydroxytryptophan; Animals; Basal Ganglia; Brain Stem; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Haplorhini; Methyldopa; Monoamine Oxidase Inhibitors; Parasympatholytics; Rats; Tremor | 1970 |
Cellular uptake of some amino acids and amines in vitro into rabbit and monkey anterior eye segment preparations.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Biological Transport, Active; Capillaries; Ciliary Body; Cocaine; Desipramine; Dihydroxyphenylalanine; Dopamine; Epithelium; Formaldehyde; Haplorhini; In Vitro Techniques; Iris; Melanocytes; Methyldopa; Methyltyrosines; Microscopy, Fluorescence; Norepinephrine; Normetanephrine; Ouabain; Pilocarpine; Quaternary Ammonium Compounds; Rabbits | 1970 |
Investigation of a case of oculocutaneous albinism.
Topics: Adult; Albinism; Catechol Oxidase; Catecholamines; Dihydroxyphenylalanine; Eye; Golgi Apparatus; Humans; Male; Melanins; Melanocytes; Methyldopa; Microscopy, Electron; Mitochondria; Skin; Skin Pigmentation; Ultraviolet Rays | 1971 |
Effect of some drugs on clinical laboratory values as determined by the Technicon SMA 12-60.
Topics: Acetaminophen; Alkaline Phosphatase; Aminosalicylic Acids; Ascorbic Acid; Aspartate Aminotransferases; Autoanalysis; Bilirubin; Blood Chemical Analysis; Blood Glucose; Chemical Phenomena; Chemistry; Cholesterol; Clinical Laboratory Techniques; Dihydroxyphenylalanine; Evaluation Studies as Topic; Humans; Isoniazid; L-Lactate Dehydrogenase; Mercaptopurine; Methyldopa; Pharmaceutical Preparations; Spectrophotometry; Sulfathiazoles; Uric Acid | 1972 |
A method for the determination of dopa and 3-O-methyldopa in the plasma of Parkinsonian patients.
Topics: Chromatography, Ion Exchange; Dihydroxyphenylalanine; Ferricyanides; Hot Temperature; Humans; Iodine; Kinetics; Methods; Methyldopa; Oxidation-Reduction; Parkinson Disease; Spectrometry, Fluorescence | 1972 |
3-methoxy-4-hydroxyphenylalanine (3-O-methyldopa) in plasma during oral L-dopa therapy of patients with Parkinson's disease.
Topics: Administration, Oral; Aluminum; Buffers; Chromatography; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Fasting; Humans; Hydrogen-Ion Concentration; Kinetics; Methods; Methyldopa; Parkinson Disease; Phenylacetates; Spectrometry, Fluorescence | 1972 |
Antagonism by dopa of morphine analgesia. A hypothesis for morphine tolerance.
Topics: Animals; Brain; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Drug Combinations; Drug Interactions; Drug Tolerance; Male; Methyldopa; Mice; Mice, Inbred Strains; Morphine; Norepinephrine; Serotonin; Time Factors | 1972 |
The induction and antagonism of central nervous system stimulant-induced stereotyped behavior in the cat.
Topics: Amphetamine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Benzyl Compounds; Cats; Central Nervous System; Cocaine; Dextroamphetamine; Dihydroxyphenylalanine; Drug Antagonism; Hydrazines; Methyldopa; Methylphenidate; Methyltyrosines; Pemoline; Reserpine; Serine; Stimulation, Chemical | 1972 |
Degeneration of central and peripheral noradrenaline neurons produced by 6-hydroxy-DOPA.
Topics: Alcohols; Animals; Animals, Newborn; Basal Ganglia; Brain; Carbon Isotopes; Cerebral Cortex; Dihydroxyphenylalanine; Heart Atria; Histocytochemistry; Hydrazines; Iris; Male; Metaraminol; Methyldopa; Mice; Microscopy, Fluorescence; Neurons; Nialamide; Norepinephrine; Receptors, Adrenergic; Receptors, Drug; Sensory Receptor Cells; Serotonin; Tritium | 1972 |
[Therapy of parkinsonian syndromes and plasmatic DOPA levels. Effects of L-DOPA and 3-OMD, administered alone or combined, with or without a decarboxylase inhibitor].
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Drug Combinations; Drug Synergism; Humans; Methyldopa; Parkinson Disease; Phenylacetates; Time Factors | 1972 |
The influence of some centrally acting drugs on sympathetic nerve activity.
Topics: Animals; Cats; Dihydroxyphenylalanine; Injections, Intraperitoneal; Methyldopa; Reserpine; Sympathetic Nervous System | 1972 |
Plasma 3-0-methyldopa in L-dopa therapy of Parkinson's disease.
Topics: Dihydroxyphenylalanine; Fasting; Humans; Methyldopa; Parkinson Disease; Phenylacetates; Time Factors | 1972 |
Levadopa and pyridoxine.
Topics: Animals; Brain; Carboxy-Lyases; Decarboxylation; Dihydroxyphenylalanine; Drug Interactions; Humans; Hydrazines; Injections, Intraperitoneal; Methyldopa; Mice; Parkinson Disease; Propionates; Pyridoxine | 1972 |
The metabolic pathways of L-3-O-methyldopa.
Topics: Amides; Animals; Brain; Carbon Dioxide; Carbon Isotopes; Catecholamines; Chromatography, Paper; Dihydroxyphenylalanine; Dopamine; Male; Methyldopa; Phenylacetates; Rats | 1972 |
Effects of L-dopa on accumulation and efflux of monoamines in particles of rat brain homogenates.
Topics: Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Dihydroxyphenylalanine; Dopamine; Hydrazines; Male; Methyldopa; Microsomes; Mitochondria; Myelin Sheath; Norepinephrine; Rats; Serotonin; Stimulation, Chemical; Synaptosomes; Tritium | 1972 |
Central monoamine metabolism in Parkinson's disease.
Topics: Adult; Aged; Dihydroxyphenylalanine; Dopamine; Evaluation Studies as Topic; Female; Humans; Hydroxyindoleacetic Acid; Male; Methyldopa; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Serotonin | 1972 |
The neurogenic component in the experimental hypertensive rat.
Topics: Animals; Blood Pressure; Depression, Chemical; Desoxycorticosterone; Dihydroxyphenylalanine; Dopamine; Furosemide; Guanidines; Hypertension, Renal; Male; Mecamylamine; Methyldopa; Methyltyrosines; Pentobarbital; Rats; Reserpine; Sodium Chloride; Sympathetic Nervous System | 1971 |
[Parkinsonism and plasma metabolism of dihydroxyphenylalanine administered with an inhibitor of decarboxylase].
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Humans; Hydrazines; Hydrochloric Acid; Methyldopa; Parkinson Disease; Phenylacetates; Sodium Hydroxide | 1971 |
L-DOPA treatment in Parkinson's disease: effect on dopamine and related substances in discrete brain regions.
Topics: Brain; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Humans; Methyldopa; Parkinson Disease; Phenylacetates | 1971 |
L-dopa and cardiac arrhythmias.
Topics: Arrhythmias, Cardiac; Dihydroxyphenylalanine; Humans; Hydrazines; Methyldopa; Parkinson Disease; Propionates | 1971 |
Metabolism of 3,4-dihydroxyphenylalanine by isolated perfused rat liver.
Topics: Amines; Animals; Ascorbic Acid; Autoradiography; Bile; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Dihydroxyphenylalanine; Erythrocytes; Glucuronates; In Vitro Techniques; Liver; Male; Methyldopa; Perfusion; Phenylacetates; Rats | 1971 |
L-3,4-dihydroxyphenylalanine-induced of norepinephrine from the rat heart.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Chlorisondamine; Dihydroxyphenylalanine; Dopamine; Female; Heart; Hydrazines; Methyldopa; Myocardium; Nerve Endings; Norepinephrine; Rats; Stimulation, Chemical; Sympathetic Nervous System; Tritium | 1971 |
[Dopa metabolism in relation to the therapy of Parkinson's syndrome].
Topics: Animals; Brain; Carboxy-Lyases; Dihydroxyphenylalanine; Humans; Methyldopa; Mice; Myocardium; Parkinson Disease; Rats | 1971 |
[Methamphetamine stimulation in mice].
Topics: Animals; Dihydroxyphenylalanine; Methamphetamine; Methyldopa; Mice; Mice, Inbred Strains; Motor Activity; Reserpine; Stimulation, Chemical; Tetrabenazine; Yohimbine | 1971 |
Synergism of levodopa by alpha methyldopa.
Topics: Aged; Dihydroxyphenylalanine; Drug Synergism; Female; Humans; Male; Methyldopa; Middle Aged; Parkinson Disease | 1971 |
Modification of L-dopa therapy of Parkinsonism by alpha-methyldopa hydrazine (MK-486).
Topics: Dihydroxyphenylalanine; Drug Synergism; Humans; Hydrazines; Methyldopa; Parkinson Disease | 1971 |
Alpha-methyldopa as an adjunct to levodopa treatment of Parkinson's disease.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Drug Synergism; Humans; Methyldopa; Parkinson Disease | 1971 |
Evidence for a dopamine inhibitory post-synaptic potential in the brain of Helix aspersa.
Topics: Action Potentials; Animals; Brain; Chlorides; Diffusion; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; Ergonovine; Glutamates; Hydroxydopamines; In Vitro Techniques; Membrane Potentials; Methyldopa; Methyltyrosines; Neural Inhibition; Osmolar Concentration; Ouabain; Potassium; Reserpine; Snails; Synapses | 1971 |
Levodopa in the treatment of Parkinsonism.
Topics: Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Dihydroxyphenylalanine; Dopamine; Esters; Humans; Hydrazines; Manganese Poisoning; Methylation; Methyldopa; Mice; Movement; Parkinson Disease; Parkinson Disease, Secondary; Phenylacetates | 1971 |
m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anticonvulsants; Atropine; Azoles; Brain; Chlordiazepoxide; Chlorpromazine; Citrates; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Drug Synergism; Kidney; Lysergic Acid Diethylamide; Male; Methyldopa; Mice; Morphine; Nialamide; Norepinephrine; Pargyline; Phenobarbital; Phenytoin; Reserpine; Seizures; Serotonin; Strychnine; Tetrabenazine; Trimethadione; Tyrosine; Urea | 1967 |
Effect of analogs of phenylalanine and tryptophan on kinetics of DOPA decarboxylase in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Dopa Decarboxylase; Hydrogen-Ion Concentration; Kinetics; Male; Methyldopa; Phenylalanine; Pyridoxal Phosphate; Rats; Tryptophan; Tyrosine | 1966 |
[Autoradiographic study of the basal clear cell in the gastric gland].
Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Chromium; Dihydroxyphenylalanine; Gastric Mucosa; Histocytochemistry; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Methyldopa; Mice; Rats; Reserpine; Serotonin; Silver; Tryptophan; Tyrosine | 1967 |
Studies on the pharmacology of alpha-methyl-3,4-dihydroxyphenylalanine (alpha-methyl-dopa) and alpha-methylnorepinephrine. II.
Topics: 5-Hydroxytryptophan; Animals; Arousal; Brain; Cats; Caudate Nucleus; Columbidae; Dihydroxyphenylalanine; Electric Stimulation; Electroencephalography; Hippocampus; Injections; Lysergic Acid Diethylamide; Methyldopa; Mice; Monoamine Oxidase Inhibitors; Nialamide; Normetanephrine; Rabbits; Reticular Formation; Sleep; Sound | 1967 |
A possible relationship between catecholamines and acute toxicity of desipramine.
Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Chlorpromazine; Desipramine; Dihydroxyphenylalanine; Disulfiram; Male; Methyldopa; Mice; Mortality; Phenylalanine; Reserpine | 1968 |
Cerebrospinal fluid monoamine metabolites and peripheral decarboxylase inhibitors in parkinsonism.
Topics: 5-Hydroxytryptophan; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; Drug Synergism; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Methyldopa; Middle Aged; Parkinson Disease; Phenylacetates | 1970 |
Some observations on aminoguanidine pharmacology.
Topics: Amino Acids; Animals; Brain; Carbachol; Carboxy-Lyases; Cats; Denervation; Dihydroxyphenylalanine; Guanidines; Guinea Pigs; Histamine; Histidine; Mecamylamine; Methyldopa; Rats; Salivation; Stomach; Submandibular Gland; Transferases | 1970 |
L-dopa-induced accumulation of 3-O-metyldopa in brain and heart.
Topics: Animals; Brain; Brain Chemistry; Carbon Isotopes; Dihydroxyphenylalanine; Dopamine; Male; Methyldopa; Myocardium; Norepinephrine; Rats; Time Factors | 1970 |
[Effect of DOPA and alpha-methyl-DOPA on the development of neurogenic dystrophy of the gastric wall and catecholamine content of the stomach].
Topics: Animals; Dihydroxyphenylalanine; Electric Stimulation; Epinephrine; Male; Methyldopa; Norepinephrine; Rats; Stomach Ulcer | 1970 |
Effects of L-dopa on efflux of cerebral monoamines from synaptosomes.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbon Isotopes; Dihydroxyphenylalanine; Dopamine; Hydrazines; Methyldopa; Nerve Endings; Neurosecretion; Norepinephrine; Propionates; Rats; Serotonin; Synapses; Tritium | 1971 |
Errors in dispensing of levodopa.
Topics: Dihydroxyphenylalanine; Drug Prescriptions; Humans; Medication Errors; Methyldopa | 1971 |
The effect of methyldopa on the excretion of catecholamines in patients with extrapyramidal disorders.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Humans; Mandelic Acids; Methyldopa; Movement Disorders; Norepinephrine; Phenylacetates | 1967 |
[Studies of the modification of central effects of 3,4-dioxyphenyl-alanine (DOPA) by alpha-methyl-dioxyphenylalanine (alpha-methyl-DOPA)].
Topics: Animals; Behavior, Animal; Dihydroxyphenylalanine; Drug Synergism; Injections, Intraperitoneal; Methyldopa; Mice; Reserpine; Stimulation, Chemical | 1967 |
Effects of alpha-methyl-dopa on conditioned behaviour in the cat.
Topics: Animals; Cats; Conditioning, Operant; Depression, Chemical; Dextroamphetamine; Dihydroxyphenylalanine; Escape Reaction; Female; Male; Methyldopa; Methyltyrosines; Reserpine | 1967 |
Mode of action of apomorphine and dexamphetamine on gnawing compulsion in rats.
Topics: Animals; Apomorphine; Chemistry, Pharmaceutical; Compulsive Behavior; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Extrapyramidal Tracts; Humans; Iproniazid; Male; Methyldopa; Parkinson Disease; Phenethylamines; Psychopharmacology; Rats | 1967 |
Drug-induced changes of extracerebral dopa metabolism in man.
Topics: Blood-Brain Barrier; Carbon Isotopes; Dihydroxyphenylalanine; Humans; Hydrazines; Intestinal Absorption; Methyldopa; Phenylacetates | 1969 |
Selective inhibition of superovulation by blockade of dopamine synthesis during the "critical period" in the immature rat.
Topics: Age Factors; Animals; Chorionic Gonadotropin; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Estrus; Female; Gonadotropins, Equine; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Methyldopa; Methyltyrosines; Norepinephrine; Normetanephrine; Organ Size; Ovary; Ovulation; Pregnancy; Rats; Time Factors; Uterus | 1969 |
Comparative metabolism of D-and L-3,4-dihydroxyphenylalanine in normal and pyridoxine-deficient rats.
Topics: Animals; Carbon Dioxide; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Methyldopa; Methyltyrosines; Rats; Urine; Vitamin B 6 Deficiency | 1964 |
[On new geminal aminocarbinol].
Topics: Aldehydes; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Methyldopa | 1965 |
Induction of pseudopregnancy in rats by depletors of endogenous catecholamines.
Topics: Aminocaproates; Amphetamine; Animals; Brain; Dihydroxyphenylalanine; Estrus; Female; Guanethidine; Iproniazid; Methyldopa; Norepinephrine; Normetanephrine; Pregnancy; Pseudopregnancy; Rats; Reserpine; Serotonin; Tetrabenazine | 1965 |
Some pharmacological agents modifying the morphine abstinence syndrome in dogs.
Topics: Animals; Dihydroxyphenylalanine; Dogs; Drug Tolerance; Humans; Methyldopa; Methyltyrosines; Morphine; Nalorphine; Nialamide; Reserpine; Substance Withdrawal Syndrome | 1965 |
Relative effects of L-DOPA and its methyl ester given orally or intraperitoneally to reserpine-treated mice.
Topics: Animals; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Methyldopa; Mice; Reserpine | 1965 |
Modification of vascular actions of sympathomimetic drugs by methyldopa.
Topics: Amphetamine; Animals; Blood Pressure; Carotid Arteries; Dihydroxyphenylalanine; Dopamine; Epinephrine; Methyldopa; Norepinephrine; Rabbits; Tyramine; Vagus Nerve | 1966 |
Drug interactions between disulfiram and alpha-methyldopa and related agents in reserpine-pretreated rats.
Topics: Animals; Blood Pressure; Carbamates; Catecholamines; Dihydroxyphenylalanine; Disulfiram; Dopamine; Methyldopa; Norepinephrine; Rats; Reserpine; Tyramine | 1966 |
Paper chromatographic identification of catecholamines.
Topics: Adrenal Medulla; Adult; Animals; Catecholamines; Child; Chromatography, Paper; Dihydroxyphenylalanine; Dogs; Dopamine; Epinephrine; Female; Fluorometry; Humans; Mandelic Acids; Methyldopa; Myocardium; Norepinephrine; Normetanephrine; Pheochromocytoma | 1966 |
Effect of methyldopa and related agents on pressor responses to tyramine in reserpine-pretreated rats and dogs.
Topics: Animals; Blood Pressure; Dihydroxyphenylalanine; Dogs; Dopamine; Hormones; Mecamylamine; Metaraminol; Methyldopa; Monoamine Oxidase Inhibitors; Norepinephrine; Normetanephrine; Rats; Reserpine; Serine; Sympathomimetics; Tyramine | 1966 |
Restoration of the response of the isolated atria of guinea-pigs to tyramine and possible significance of beta-hydroxylation.
Topics: Amines; Animals; Dihydroxyphenylalanine; Disulfiram; Dopamine; Guinea Pigs; Heart Atria; Heart Conduction System; In Vitro Techniques; Male; Methyldopa; Myocardium; Norepinephrine; Rats; Reserpine; Sinoatrial Node; Tritium; Tyramine | 1966 |
The mechanism of action of anticonvulsants. II. Acetazolamide.
Topics: Acetazolamide; Animals; Dextroamphetamine; Dihydroxyphenylalanine; Electric Stimulation; Electroshock; Enzymes; Male; Methyldopa; Mice; Reserpine; Seizures; Stress, Physiological; Tyrosine | 1966 |
The effect of the optical isomers of alpha-methyl-p-tyrosine upon brain and heart catecholamines in the mouse.
Topics: Animals; Brain; Carbon Isotopes; Catecholamines; Dihydroxyphenylalanine; Enzymes; Female; Methyldopa; Methyltyrosines; Mice; Myocardium; Norepinephrine; Tritium; Tyrosine | 1966 |
The effect of DOPA, alpha-methyldopa and reserpine on the dopamine content of the brain of the snail, Helix aspersa.
Topics: Animals; Brain Chemistry; Catecholamines; Chromatography, Paper; Crustacea; Dihydroxyphenylalanine; Dopamine; Leeches; Methyldopa; Nervous System; Reserpine; Snails | 1966 |
[On the problem of the metabolism of dopamine in the brain of patients with parkinsonism].
Topics: Brain; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Humans; Methyldopa; Parkinson Disease | 1966 |
[What success does L-Dopa have in the treatment of parkinsonian akinesia?].
Topics: Aged; Biperiden; Blood-Brain Barrier; Desipramine; Dihydroxyphenylalanine; Dopa Decarboxylase; Female; Humans; Infusions, Parenteral; Male; Methyldopa; Middle Aged; Parasympatholytics; Parkinson Disease | 1967 |
Antagonism of the conversion of alpha-methyldopa to an active symphathomimetic by 3-hydroxy-4-bromobenzyloxyamine (NSD 1055) and 3-hydroxybenzyloxyamine (NSD 1024).
Topics: Aniline Compounds; Animals; Blood Pressure; Dihydroxyphenylalanine; Dopamine; Methyldopa; Mixed Function Oxygenases; Norepinephrine; Rats; Sympathomimetics; Tyramine | 1967 |
Evidence for a neurotransmitter role for 5-hydroxytryptamine in chick retina.
Topics: 5-Hydroxytryptophan; Animals; Chickens; Darkness; Dihydroxyphenylalanine; Dopamine; Kinetics; Light; Methyldopa; Neurotransmitter Agents; Pargyline; Retina; Serotonin | 1981 |
Assay of L-aromatic amino acid decarboxylase by high performance liquid chromatography.
Topics: Aromatic-L-Amino-Acid Decarboxylases; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopa Decarboxylase; Methyldopa | 1980 |
[Role of GABA-ergic and dopaminergic mechanisms in the withdrawal syndrome after discontinuation of long-term phenazepam administration].
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Brain; Dihydroxyphenylalanine; Disulfiram; Dopamine; gamma-Aminobutyric Acid; Humans; Male; Methyldopa; Rats; Semicarbazides; Substance Withdrawal Syndrome; Valproic Acid | 1980 |
Reversed-phase ion-pair partion chromatography of biogenic catecholamines and their alpha-methyl homologues with tributylphosphate as stationary phase.
Topics: 5-Methoxytryptamine; Catecholamines; Chromatography, Ion Exchange; Deoxyepinephrine; Dihydroxyphenylalanine; Dopamine; Epinephrine; Metanephrine; Methyldopa; Norepinephrine | 1980 |
Endogenous dopa in rat brain. Occurrence, distribution and relationship to changes i catecholamine synthesis.
Topics: alpha-Methyltyrosine; Animals; Brain; Brain Chemistry; Catecholamines; Dihydroxyphenylalanine; Male; Methyldopa; Methyltyrosines; Rats | 1981 |
Thiol compounds. III Synthesis and antihypertensive activity of mercaptoacylamino acids.
Topics: Amino Acids; Animals; Antihypertensive Agents; Dihydroxyphenylalanine; Methyldopa; Phenylalanine; Sulfhydryl Compounds; Tyrosine | 1981 |
Dopamine metabolism following irreversible inactivation of aromatic amino acid decarboxylase in retina.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Chickens; Darkness; Dihydroxyphenylalanine; Dopamine; Kinetics; Light; Methyldopa; Rabbits; Retina | 1981 |
[Alpha-methyldopa and brain monoamines].
Topics: Animals; Antihypertensive Agents; Biotransformation; Brain; Catecholamines; Dihydroxyphenylalanine; Female; Gestational Age; Hypertension; Male; Methyldopa; Neurons; Nordefrin; Pregnancy; Rats; Rats, Inbred Strains; Spinal Cord; Sympathectomy, Chemical | 1982 |
Irreversible inhibition of aromatic-L-amino acid decarboxylase by alpha-difluoromethyl-DOPA and metabolism of the inhibitor.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Catechol O-Methyltransferase; Dihydroxyphenylalanine; Kidney; Levodopa; Methylation; Methyldopa; Pyridoxal Phosphate; Rats; Swine | 1980 |
Determination of alpha-methyldopa in human plasma by validated high-performance liquid chromatography with fluorescence detection.
Topics: Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Humans; Indicators and Reagents; Methyldopa; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 1996 |
Separation of aromatic acids, DOPA, and methyl-DOPA by capillary electrophoresis with dendrimers as buffer additives.
Topics: Biocompatible Materials; Buffers; Carboxylic Acids; Dendrimers; Dihydroxyphenylalanine; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Methyldopa; Polyamines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 1998 |
Chiral separation of alpha-amino acids by ligand-exchange capillary electrophoresis using N-(2-hydroxy-octyl)-L-4-hydroxyproline as a selector.
Topics: Amino Acids; Copper; Dihydroxyphenylalanine; Electrolytes; Electrophoresis, Capillary; Histidine; Hydrogen-Ion Concentration; Hydroxyproline; Methyldopa; Octanes; Sodium Hydroxide; Stereoisomerism | 1998 |
Enantiomeric separation of dihydroxyphenylalanine (DOPA), methyldihydroxyphenylalanine (MDOPA) and hydrazinomethyldihydroxyphenylalanine (CDOPA) by using capillary electrophoresis with sulfobutyl ether-beta-cyclodextrin as a chiral selector.
Topics: beta-Cyclodextrins; Carbidopa; Cyclodextrins; Dihydroxyphenylalanine; Electrophoresis, Capillary; Indicators and Reagents; Methyldopa; Stereoisomerism | 2000 |
Catechol-O-methyltransferase inhibition in erythrocytes and liver by BIA 3-202 (1-[3,4-dibydroxy-5-nitrophenyl]-2-phenyl-ethanone).
Topics: Acetophenones; Administration, Oral; Animals; Antiparkinson Agents; Benserazide; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Drug Interactions; Erythrocytes; Humans; In Vitro Techniques; Levodopa; Liver; Methylation; Methyldopa; Microdialysis; Rats; Rats, Wistar | 2003 |
[Inhibition of serotonin formation by alpha-methyl-DOPA].
Topics: Antihypertensive Agents; Biochemical Phenomena; Dihydroxyphenylalanine; Methyldopa; Serotonin; Serotonin Antagonists | 1958 |
[Inhibition of DOPA decarboxylase by alpha-methyl-DOPA in vivo].
Topics: Dihydroxyphenylalanine; Dopa Decarboxylase; Lyases; Methyldopa | 1958 |
Use of alpha-methyl-dopa (alpha-methyl-3,4-dihydroxy-DL-phenylalanine) in the management of the carcinoid syndrome.
Topics: Dihydroxyphenylalanine; Disease Management; Humans; Lyases; Malignant Carcinoid Syndrome; Methyldopa; Phenylalanine | 1961 |
Preliminary report on trial of l-alpha-methyl dopa (Aldomet) in the treatment of hypertension.
Topics: Dihydroxyphenylalanine; Hypertension; Methyldopa | 1961 |
Serotonin synthesis in carcinoid patients. Its inhibition by alpha-methyl-dopa, with measurement of associated increases in urinary 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Carcinoid Tumor; Carcinoma, Neuroendocrine; Dihydroxyphenylalanine; Humans; Malignant Carcinoid Syndrome; Methyldopa; Serotonin | 1960 |
The pharmacological actions of 3,4-dihydroxyphenyl-alpha-methylalanine (alpha-methyldopa), an inhibitor of 5-hydroxytryptophan decarboxylase.
Topics: Aminoisobutyric Acids; Animals; Aromatic-L-Amino-Acid Decarboxylases; Brain; Dihydroxyphenylalanine; Lyases; Methyldopa; Mice; Reserpine; Serotonin | 1960 |
[Value of alpha-methyl-dopa for the treatment of chronic hypertension].
Topics: Dihydroxyphenylalanine; Hypertension; Methyldopa | 1962 |
Clinical trial of a new hypotensive drug, methyldopa ("aldomet").
Topics: Antihypertensive Agents; Dihydroxyphenylalanine; Hypertension; Methyldopa | 1962 |
Methyldopa in the treatment of hypertension.
Topics: Dihydroxyphenylalanine; Hypertension; Methyldopa | 1962 |
Effect of alpha-methyl DOPA in severe and malignant hypertension.
Topics: Dihydroxyphenylalanine; Hypertension; Hypertension, Malignant; Methyldopa | 1962 |
In-vivo decarboxylation of alpha-methyl DOPA and alpha-methyl metatyrosine.
Topics: Decarboxylation; Dihydroxyphenylalanine; Humans; Methyldopa; Methyltyrosines | 1962 |
Another hypotensive agent--methyldopa.
Topics: Antihypertensive Agents; Dihydroxyphenylalanine; Methyldopa | 1962 |
Metabolic studies in carcinoid syndrome: observations on use of alpha-methyl DOPA, isonicotinic acid hydrazide and selective tryptophan deficiency.
Topics: Dihydroxyphenylalanine; Humans; Isoniazid; Malignant Carcinoid Syndrome; Methyldopa; Serotonin; Tryptophan | 1961 |
Methyldopa in hypertension. Clinical and pharmacological studies.
Topics: Dihydroxyphenylalanine; Hypertension; Methyldopa; Research | 1962 |
Alpha methyl dopa in the treatment of hypertension.
Topics: Dihydroxyphenylalanine; Hypertension; Methyldopa | 1962 |
The effect of alpha-methyl DOPA and some other decarboxylase inhibitors on brain 5-hydroxtryptamine.
Topics: Brain; Carboxy-Lyases; Dihydroxyphenylalanine; Methyldopa | 1962 |
[On the therapeutic use of alpha-methyl-DOPA in the carcinoid syndrome].
Topics: Dihydroxyphenylalanine; Humans; Malignant Carcinoid Syndrome; Methyldopa | 1961 |
[Preliminary report on the clinical effectiveness of 1-alpha-methyl-DOPA (Aldomet) in the treatment of hypertension].
Topics: Dihydroxyphenylalanine; Hypertension; Methyldopa; Treatment Outcome | 1961 |
[Trial of alpha-methyl-dopa in a case of carcinoidosis].
Topics: Carcinoid Tumor; Dihydroxyphenylalanine; Humans; Methyldopa; Serotonin; Tryptophan | 1962 |
Clinical and chemical studies with alpha-methyl-dopa in patients with hypertension.
Topics: Dihydroxyphenylalanine; Hypertension; Methyldopa | 1962 |
Agranulocytosis caused by methyl dopa (Aldomet).
Topics: Agranulocytosis; Dihydroxyphenylalanine; Methyldopa | 1961 |
The effects of alpha-methyl-DOPA and alpha-methyl-metatyrosine on the metabolism of norepinephrine and serotonin in vivo.
Topics: Dihydroxyphenylalanine; Methyldopa; Methyltyrosines; Norepinephrine; Serotonin; Tyrosine | 1961 |
Effect of alpha-methyl-3,4-dihydroxyphenylalanine (methyldopa), reserpine and related agents on some vascular responses in the dog.
Topics: Animals; Dihydroxyphenylalanine; Dogs; Methyldopa; Reserpine | 1962 |
Intraocular pressure studies with alpha-methyl-dopa.
Topics: Dihydroxyphenylalanine; Humans; Intraocular Pressure; Methyldopa; Tonometry, Ocular | 1962 |
[Etiology and treatment of retinitis pigmentosa. XI. Clinical results with alpha-methyl-DOPA].
Topics: Dihydroxyphenylalanine; Humans; Methyldopa; Retinitis Pigmentosa | 1963 |
Spurious elevation of urinary catecholamines during therapy with alpha-methyl-dopa. A diagnostic pitfall.
Topics: Catecholamines; Dihydroxyphenylalanine; Humans; Hypertension; Methyldopa | 1962 |
Guanethidine and methyldopa as therapeutic agents in hypertension. A comparative review.
Topics: Dihydroxyphenylalanine; Guanethidine; Humans; Hypertension; Methyldopa | 1963 |
Agranulocytosis with alpha methyl DOPA.
Topics: Agranulocytosis; Dihydroxyphenylalanine; Drug Hypersensitivity; Humans; Methyldopa | 1962 |
[The use of the combination of L-alpha-methyldopa and dichlorothiazide in the treatment of arterial hypertension].
Topics: Chlorothiazide; Dihydroxyphenylalanine; Hypertension; Methyldopa | 1962 |
The effect of alpha-methyl DOPA on the metabolism of 5-hydroxythryptamine in brain.
Topics: Brain; Dihydroxyphenylalanine; Methyldopa; Monoamine Oxidase Inhibitors; Serotonin | 1963 |
[The effect of intravenously administered DOPA on the blood pressure in pretreated alpha-methyl-DOPA hypertensives. Studies on the blood pressure-lowering mechanism of alpha-methyl-DOPA].
Topics: Antihypertensive Agents; Blood Pressure; Carboxy-Lyases; Dihydroxyphenylalanine; Hypertension; Hypotension; Methyldopa; Norepinephrine | 1962 |
[The effects of reserpine, guanethidine and alpha-methyl-DOPA on resistance to cold].
Topics: Cold Temperature; Dihydroxyphenylalanine; Guanethidine; Methyldopa; Reserpine | 1963 |
Clinical evaluation of alpha methyl-dopa.
Topics: Dihydroxyphenylalanine; Humans; Hypertension; Methyldopa | 1963 |
[A new hypotensive drug: a-methylDopa].
Topics: Antihypertensive Agents; Dihydroxyphenylalanine; Methyldopa | 1962 |
The acute hemodynamic eeffects of alpha-methyldopa in man.
Topics: Dihydroxyphenylalanine; Hemodynamics; Hypertension; Methyldopa | 1962 |
[Trial treatment of 2 cases of carcinoid syndrome with alpha-methyl-dopa].
Topics: Dihydroxyphenylalanine; Humans; Malignant Carcinoid Syndrome; Methyldopa | 1962 |
[Evaluation of the hypotensive effect of aldomet (alpha-methyl DOPA) in the treatment of arterial hypertension, with reference to its effect on the metabolism of catecholamines].
Topics: Catecholamines; Dihydroxyphenylalanine; Hypertension; Hypotension; Methyldopa | 1962 |
The effect of L-alpha-methyl DOPA and N-2-hydroxybenzyl-N-methyl hydrazine (NSD 1039) on the blood pressure of renal hypertensive rates.
Topics: Blood Pressure; Dihydroxyphenylalanine; Hydrazines; Hypertension; Hypertension, Renal; Kidney; Methyldopa; Methylhydrazines | 1963 |
Methyldopa in hypertension.
Topics: Dihydroxyphenylalanine; Humans; Hypertension; Methyldopa | 1963 |
[Methyl-DOPA (Aldomet) in the treatment of high blood pressure].
Topics: Dihydroxyphenylalanine; Hypertension; Methyldopa | 1963 |
[Clinical experience with alpha-methyl DOPA and its effect on the metabolism of serotonin and catecholmine].
Topics: Catecholamines; Dihydroxyphenylalanine; Methyldopa; Serotonin | 1962 |
EFFECTS OF ALPHA-METHYL DOPA AND DOPA ON THE AMPHETAMINE EXCITATORY RESPONSE IN RESERPINIZED RATS.
Topics: Amphetamine; Amphetamines; Antihypertensive Agents; Dihydroxyphenylalanine; Metabolism; Methyldopa; Pharmacology; Rats; Research; Reserpine | 1963 |
[PHEOCHROMOCYTOMA AS A CAUSE OF CURABLE ARTERIAL HYPERTENSION. PRESENTATION OF A NEW CASE].
Topics: Adolescent; Angiography; Antihypertensive Agents; Dihydroxyphenylalanine; Hypertension; Methyldopa; Pathology; Phentolamine; Pheochromocytoma; Surgical Procedures, Operative | 1963 |
[ACTION OF ALPHA-METHYLDOPA (AMD) ON EMOTIONAL BEHAVIOR OBJECTIFIED BY "GROUP TOXICITY" PRODUCED BY DL-AMPHETAMINE AND DL-DIHYDROXYPHENYLALANINE IN MICE].
Topics: Amphetamine; Amphetamines; Behavior, Animal; Dihydroxyphenylalanine; Emotions; Methyldopa; Mice; Pharmacology; Research; Toxicology | 1963 |
[EFFECT OF THE DOPA-DECARBOXYLASE INHIBITOR ALPHA-METHYLDOPA ON THE INCORPORATION OF DOPA INTO MELANIN AND PYROCATECHOLAMINE. IN VIVO STUDIES ON MELANOMA MICE WITH TRITIATED DOPA].
Topics: Animals; Antihypertensive Agents; Autoradiography; Catecholamines; Dihydroxyphenylalanine; Dopa Decarboxylase; Enzyme Inhibitors; Melanins; Melanoma; Metabolism; Methyldopa; Mice; Neoplasms, Experimental; Pharmacology; Research; Tritium | 1963 |
METABOLISM OF DOPA-14C IN THE NORMAL AND ALPHA-METHYLDOPATREATED MOUSE.
Topics: Animals; Antihypertensive Agents; Carbon Isotopes; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Enzyme Inhibitors; Epinephrine; Metabolism; Methyldopa; Mice; Norepinephrine; Pharmacology; Research | 1963 |
[EFFECTS OF RESERPINE, ALPHA-METHYL-DOPA AND THEIR INTERACTIONS ON MORPHINE ANALGESIA].
Topics: Analgesia; Animals; Antihypertensive Agents; Catecholamines; Dihydroxyphenylalanine; Electricity; Hot Temperature; Injections; Methyldopa; Mice; Morphine; Pain; Pharmacology; Research; Reserpine; Selective Serotonin Reuptake Inhibitors; Serotonin | 1963 |
ENHANCEMENT BY RESERPINE AND ALPHA-METHYL DOPA OF THE EFFECTS OF D-AMPHETAMINE UPON THE LOCOMOTOR ACTIVITY OF MICE.
Topics: Antihypertensive Agents; Brain; Cocaine; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Locomotion; Methyldopa; Mice; Motor Activity; Pharmacology; Piperidines; Research; Reserpine; Serotonin | 1963 |
STUDIES ON MORPHINE. III. ACTION OF METABOLIC PRECURSORS TO SEROTONIN AND NORADRENALINE AND RELATED SUBSTANCES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
Topics: Brain; Catecholamines; Dihydroxyphenylalanine; Ergot Alkaloids; Iproniazid; Kynurenine; Lysergic Acid Diethylamide; Methyldopa; Mice; Morphine; Nalorphine; Norepinephrine; ortho-Aminobenzoates; Pharmacology; Phenylalanine; Research; Serotonin; Shikimic Acid; Toxicology; Tryptophan; Tyrosine | 1963 |
THE ROLE OF THE NERVOUS SYSTEM IN REGENERATING HYDRA: THE EFFECT OF NEUROPHARMACOLOGICAL AGENTS.
Topics: Amphetamine; Amphetamines; Animals; Atropine; Autonomic Agents; Biphenyl Compounds; Chlorpromazine; Cnidaria; Decamethonium Compounds; Dihydroxyphenylalanine; Enzyme Inhibitors; Ergotamine; Hexamethonium Compounds; Histocytochemistry; Histology; Hydra; Isoflurophate; Lidocaine; Methyldopa; Nervous System; Pharmacology; Physostigmine; Regeneration; Research; Reserpine; Tubocurarine | 1963 |
EFFECT OF ALPHA-METHYL-DOPA ON MYOCARDIAL CATECHOLAMINES.
Topics: Animals; Blood Pressure; Blood Pressure Determination; Catecholamines; Dihydroxyphenylalanine; Guinea Pigs; Metabolism; Methyldopa; Mice; Myocardium; Norepinephrine; Pharmacology; Rats; Research; Tissue Extracts | 1963 |
[THE PSYCHOPHYSIOLOGICAL EFFECTS OF METHYLDOPA].
Topics: Blood Pressure; Blood Pressure Determination; Depression; Depressive Disorder; Dihydroxyphenylalanine; Hypertension; Imipramine; Methyldopa; Psychopharmacology; Schizophrenia | 1963 |
[ANTIHYPERTENSIVE ACTION OF A DOPA-DECARBOXYLASE INHIBITOR: METHYLDOPA].
Topics: Antihypertensive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Carboxy-Lyases; Chemistry, Pharmaceutical; Dihydroxyphenylalanine; Methyldopa; Pharmacology; Pharmacy | 1963 |
SOME OBSERVATIONS ON THE PHARMACOLOGY OF ALPHA-METHYLDOPA.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Carotid Sinus; Cats; Deoxyepinephrine; Dihydroxyphenylalanine; Dogs; Dopamine; Guinea Pigs; Humans; Ileum; Lagomorpha; Male; Methyldopa; Nictitating Membrane; Nordefrin; Norepinephrine; Pharmacology; Pressoreceptors; Rabbits; Rats; Research; Reserpine; Spleen; Sympathetic Nervous System; Tyramine; Vas Deferens | 1964 |
STUDIES ON THE SPECIFICITY OF TYROSINE-ALPHA-KETOGLUTARATE TRANSAMINASE.
Topics: 5-Hydroxytryptophan; Alanine; Amphetamine; Benzoates; Butyrates; Catecholamines; Dihydroxyphenylalanine; Enzyme Inhibitors; Ephedrine; Indoleacetic Acids; Ketoglutaric Acids; Lactates; Liver; Mandelic Acids; Methyldopa; Normetanephrine; Pharmacology; Phenylacetates; Phenylalanine; Propionates; Rats; Research; Transaminases; Tryptophan; Tyramine; Tyrosine; Tyrosine Transaminase | 1964 |
[5-HYDROXYTRYPTOPHAN DOPA DECARBOXYLASE IN NERVOUS AND CARDIAC TISSUES IN THE MOLLUSC HELIX POMATIA. INTERACTION OF SUBSTRATES IN VITRO].
Topics: 5-Hydroxytryptophan; Aromatic-L-Amino-Acid Decarboxylases; Dihydroxyphenylalanine; Dopa Decarboxylase; Heart; In Vitro Techniques; Methyldopa; Mollusca; Myocardium; Nerve Tissue; Physiology, Comparative; Research; Serotonin; Tryptophan; Tyrosine | 1964 |
ANALOGS OF METHYLDOPA AND DOPA. HYDANTOIC ACIDS AND HYDANTOINS.
Topics: Antihypertensive Agents; Chemistry, Pharmaceutical; Dihydroxyphenylalanine; Hydantoins; Methyldopa; Organic Chemicals; Research; Urea | 1964 |
STUDIES ON THE ABSORPTION, METABOLISM AND EXCRETION OF METHYLDOPA AND OTHER CATECHOLS AND THEIR INFLUENCE ON AMINO ACID TRANSPORT IN RATS.
Topics: Absorption; Amino Acids; Bile; Biological Transport; Blood; Body Fluids; Catechols; Dihydroxyphenylalanine; Dopamine; Fluids and Secretions; Glucuronates; Kidney; Metabolism; Methyldopa; Pharmacology; Rats; Renal Aminoacidurias; Research; Serum Albumin; Serum Globulins; Urine | 1964 |
[ACTION OF 5-HTP/DOPA DECARBOXYLASE INHIBITORS ON DIURESIS, URINARY ELECTROLYTES AND RELEASE OF THE ANTIDIURETIC HORMONE].
Topics: 5-Hydroxytryptophan; Arginine Vasopressin; Aromatic Amino Acid Decarboxylase Inhibitors; Carboxy-Lyases; Cinnamates; Dihydroxyphenylalanine; Diuresis; Electrolytes; Enzyme Inhibitors; Methyldopa; Natriuresis; Physiology; Potassium; Rats; Research; Serotonin; Urine; Vasopressins | 1964 |
DISSOCIATION OF THE DECARBOXYLASE-INHIBITING AND NOREPINEPHRINE-DEPLETING EFFECTS OF ALPHA-METHYL-DOPA, ALPHA-ETHYL-DOPA, 4-BROMO-3-HYDROXY-BENZYLOXYAMINE AND RELATED SUBSTANCES.
Topics: Amines; Brain Chemistry; Carboxy-Lyases; Dihydroxyphenylalanine; Enzyme Inhibitors; Guinea Pigs; Hydroxylamines; Metabolism; Methyldopa; Myocardium; Norepinephrine; Pharmacology; Research | 1964 |
A CLINICAL AND METABOLIC STUDY OF DOPA (3, 4-DIHYDROXYPHENYLALANINE) AND METHYLDOPA IN HUNTINGTON'S CHOREA.
Topics: Body Fluids; Chorea; Dihydroxyphenylalanine; Drug Therapy; Electroencephalography; Fluids and Secretions; Humans; Huntington Disease; Injections; Injections, Intravenous; Leriche Syndrome; Metabolism; Methyldopa; Parkinsonian Disorders; Urine | 1965 |
MULTIPLE INHIBITORY EFFECTS OF ALPHA-METHYLAMINO ACIDS ON THE METABOLISM OF C14-LABELED TYROSINE, DOPA AND ALPHA-METHYLDOPA.
Topics: Amino Acid Oxidoreductases; Amino Acids; Carbon Isotopes; Carboxy-Lyases; D-Amino-Acid Oxidase; Dihydroxyphenylalanine; Enzyme Inhibitors; Metabolism; Methyldopa; Pharmacology; Radiometry; Rats; Research; Tyrosine | 1965 |
[CLINICAL EXPERIENCES WITH ALPHA-METHYL-DOPA, A DECARBOXYLASE INHIBITOR].
Topics: Carboxy-Lyases; Dihydroxyphenylalanine; Enzyme Inhibitors; Methyldopa | 1965 |
EFFECT OF CATECHOLAMINE PRECURSORS AND PHENYLETHYLAMINES ON SPONTANEOUS ACTIVITY AND ON THE RESPONSE TO METHOHEXITAL ANAESTHESIA.
Topics: Amphetamine; Amphetamines; Anesthesia; Anesthetics; Animals; Arousal; Behavior, Animal; Catecholamines; Dihydroxyphenylalanine; Dopamine; Electroencephalography; Hypnosis; Hypnosis, Anesthetic; Methohexital; Methyldopa; Phenethylamines; Psychopharmacology; Rats; Research; Tyramine; Tyrosine | 1965 |
Pharmacodynamics and clinical use of guanethidine, bretylium and methyldopa.
Topics: Amidines; Antitubercular Agents; Bretylium Compounds; Dihydroxyphenylalanine; Guanethidine; Humans; Hypertension; Lyases; Methyldopa; Sympatholytics | 1962 |
Febrile reactions to L-alpha-methyl-dopa. Report of three cases.
Topics: Dihydroxyphenylalanine; Fever; Methyldopa | 1962 |
5-Hydroxytryptamine levels in brain of mice pretreated with Alpha-methyl-dopa.
Topics: Animals; Brain; Dihydroxyphenylalanine; Methyldopa; Mice; Neurochemistry; Serotonin | 1961 |
[Methyl-dopa (Aldomet), a new principle in the treatment of high blood pressure].
Topics: Dihydroxyphenylalanine; Hypertension; Methyldopa | 1962 |
Antagonism between L-alpha-methyl DOPA and reserpine.
Topics: Dihydroxyphenylalanine; Methyldopa; Reserpine | 1962 |
Effect of methyldopa in carcinoid disease.
Topics: Carcinoid Tumor; Carcinoma, Neuroendocrine; Dihydroxyphenylalanine; Humans; Malignant Carcinoid Syndrome; Methyldopa | 1962 |
A case of carcinoid syndrome, with an account of the use of alpha-methyl-dopa.
Topics: Dihydroxyphenylalanine; Humans; Malignant Carcinoid Syndrome; Methyldopa | 1961 |
Pharmacodynamic effects and clinical use of alpha methyldopa in the treatment of essential hypertension.
Topics: Antihypertensive Agents; Dihydroxyphenylalanine; Essential Hypertension; Humans; Hypertension; Methyldopa | 1962 |
[alpha-Methyl-DOPA. Therapeutic experiences in hypertension and biochemical research on its mode of action].
Topics: Dihydroxyphenylalanine; Hypertension; Methyldopa; Research | 1962 |
Enantioseparation of dopa and related compounds by cyclodextrin-modified microemulsion electrokinetic chromatography.
Topics: Amino Acids, Aromatic; Chromatography; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Dihydroxyphenylalanine; Hydrogen-Ion Concentration; Methyldopa; Phenylalanine; Reproducibility of Results; Stereoisomerism; Tyrosine | 2008 |