dihydroxyphenylalanine has been researched along with entacapone in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (71.43) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lindén, IB; Nissinen, E; Pohto, P; Schultz, E | 1 |
| Lang, A; Männistö, PT; Rauhala, P; Vasar, E | 1 |
| Gordin, A; Kaakkola, S; Männistö, PT | 1 |
| Brooks, DJ; Burn, DJ; Lammertsma, AA; Luthra, S; Morrish, PK; Osman, S; Sawle, GV; Snow, BJ | 1 |
| Dethy, S; Goldman, S; Luxen, A; Monclus, M; Pauwels, T | 1 |
| Cedarbaum, JM; Evans, A; Gjedde, A; Guttman, M; Kuwabara, H; Léger, G; Reches, A | 1 |
| Kaakkola, S; Wurtman, RJ | 1 |
| Antonini, A; Beer, HF; Günther, I; Nickles, RJ; Psylla, M; Reddy, GN; Reist, HW; Schubiger, PA; Vontobel, P; Zollinger, A | 1 |
| Belakhlef, A; Chaly, T; Dahl, R; Dhawan, V; Eidelberg, D; Ishikawa, T; Mandel, F; Margouleff, C; Robeson, W | 1 |
| Bergman, JR; Haaparanta, MT; Laihinen, AO; Oikonen, VJ; Rinne, JO; Rinne, UK; Ruotsalainen, UH; Ruottinen, HM; Solin, OH | 1 |
| Bergman, J; Eronen, E; Eskola, O; Niinivirta, M; Oikonen, V; Rinne, UK; Ruottinen, HM; Solin, O; Sonninen, P | 1 |
| Muhlack, S; Müller, T | 1 |
| Cardoso, MA; de Carvalho, KA; de Francisco, TM; de Oliveira Vilhena, R; Gasparetto, JC; Guimarães de Francisco, TM; Martins, CA; Pontarolo, R; Ribeiro, RP | 1 |
| Asanuma, M; Miyazaki, I | 1 |
1 review(s) available for dihydroxyphenylalanine and entacapone
| Article | Year |
|---|---|
General properties and clinical possibilities of new selective inhibitors of catechol O-methyltransferase.
Topics: Animals; Behavior, Animal; Benzophenones; Catechol O-Methyltransferase Inhibitors; Catecholamines; Catechols; Dihydroxyphenylalanine; Humans; Levodopa; Microdialysis; Nitriles; Nitrophenols; Pentanones; Tolcapone; Tomography, Emission-Computed | 1994 |
2 trial(s) available for dihydroxyphenylalanine and entacapone
| Article | Year |
|---|---|
The effect of entacapone (OR-611) on brain [18F]-6-L-fluorodopa metabolism: implications for levodopa therapy of Parkinson's disease.
Topics: Aged; Brain; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Drug Synergism; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Nitriles; Occipital Lobe; Parkinson Disease; Tomography, Emission-Computed | 1994 |
Striatal [18F]fluorodopa utilization after COMT inhibition with entacapone studied with PET in advanced Parkinson's disease.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitriles; Parkinson Disease; Tomography, Emission-Computed | 1995 |
11 other study(ies) available for dihydroxyphenylalanine and entacapone
| Article | Year |
|---|---|
Biochemical and pharmacological properties of a peripherally acting catechol-O-methyltransferase inhibitor entacapone.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Duodenum; Erythrocytes; Homovanillic Acid; In Vitro Techniques; Liver; Male; Nitriles; Rats; Rats, Wistar; Tyrosine | 1992 |
Beneficial effects of co-administration of catechol-O-methyltransferase inhibitors and L-dihydroxyphenylalanine in rat models of depression.
Topics: Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Depression; Desipramine; Dihydroxyphenylalanine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Levodopa; Male; Motor Activity; Nitriles; Nitrophenols; Rats; Rats, Wistar; Swimming; Tolcapone | 1995 |
Effect of catechol-O-methyl transferase inhibition on peripheral and central metabolism of 6-[18F]fluoro-L-dopa.
Topics: Animals; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Cerebellum; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Fluorine Radioisotopes; Male; Nitriles; Rats; Rats, Wistar | 1994 |
Administration of the new COMT inhibitor OR-611 increases striatal uptake of fluorodopa.
Topics: Animals; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Fluorine Radioisotopes; Levodopa; Macaca fascicularis; Magnetic Resonance Imaging; Male; Nitriles; Parkinson Disease; Tomography, Emission-Computed | 1993 |
Effects of catechol-O-methyltransferase inhibitors and L-3,4-dihydroxyphenylalanine with or without carbidopa on extracellular dopamine in rat striatum.
Topics: Animals; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Extracellular Space; Male; Nitriles; Nitrophenols; Rats; Rats, Sprague-Dawley; Tolcapone; Tyrosine | 1993 |
Positron emission tomography in drug evaluation: influence of three different catechol-O-methyltransferase inhibitors on metabolism of [NCA] 6-[18F]fluoro-L-dopa in rhesus monkey.
Topics: Amidines; Animals; Benzophenones; Biological Availability; Brain; Catechol O-Methyltransferase Inhibitors; Catechols; Dihydroxyphenylalanine; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Fluorine Radioisotopes; Macaca mulatta; Nitriles; Nitrophenols; Pyridones; Tolcapone; Tomography, Emission-Computed | 1995 |
Fluorodopa positron emission tomography with an inhibitor of catechol-O-methyltransferase: effect of the plasma 3-O-methyldopa fraction on data analysis.
Topics: Adult; Aged; Catechol O-Methyltransferase Inhibitors; Catechols; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Enzyme Inhibitors; Female; Fluorine Radioisotopes; Humans; Kinetics; Male; Middle Aged; Nitriles; Occipital Lobe; Parkinson Disease; Quality Control; Sensitivity and Specificity; Tomography, Emission-Computed; Tyrosine | 1996 |
Detection of response to COMT inhibition in FDOPA PET in advanced Parkinson's disease requires prolonged imaging.
Topics: Aged; Antiparkinson Agents; Brain; Catechol O-Methyltransferase; Catechols; Dihydroxyphenylalanine; Female; Humans; Levodopa; Male; Middle Aged; Movement; Nitriles; Parkinson Disease; Time Factors; Tomography, Emission-Computed | 2001 |
Peripheral COMT inhibition prevents levodopa associated homocysteine increase.
Topics: Adult; Aged; Aged, 80 and over; Antiparkinson Agents; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Delayed-Action Preparations; Dihydroxyphenylalanine; Enzyme Inhibitors; Female; Homocysteine; Humans; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Time Factors; Tyrosine | 2009 |
Simultaneous determination of levodopa, carbidopa, entacapone, tolcapone, 3-O-methyldopa and dopamine in human plasma by an HPLC-MS/MS method.
Topics: Benzophenones; Blood Chemical Analysis; Carbidopa; Catechols; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Humans; Levodopa; Nitriles; Nitrophenols; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry; Tolcapone; Tyrosine | 2015 |
3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of L-DOPA.
Topics: Animals; Astrocytes; Catechol O-Methyltransferase Inhibitors; Catechols; Cells, Cultured; Corpus Striatum; Dihydroxyphenylalanine; Dopamine Agents; Dopaminergic Neurons; Dose-Response Relationship, Drug; Glutathione; Levodopa; Mesencephalon; Neuroprotection; Neuroprotective Agents; Nitriles; Rats, Sprague-Dawley; Tyrosine | 2016 |