dihydroxyphenylalanine and 3-methoxytyrosine

dihydroxyphenylalanine has been researched along with 3-methoxytyrosine in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199010 (22.73)18.7374
1990's13 (29.55)18.2507
2000's11 (25.00)29.6817
2010's10 (22.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lindén, IB; Nissinen, E; Pohto, P; Schultz, E1
Cedarbaum, JM; Diksic, M; Evans, A; Gjedde, A; Guttman, M; Léger, G; Reches, A; Woodward, W1
Adam, MJ; Chan, GL; Hewitt, KA; Pate, BD; Ruth, TJ; Schofield, P1
Abe, T; Kikuchi, T; Nozaki, Y; Takahashi, S; Tohgi, H1
Da Prada, M; Zürcher, G1
De Herdt, P; Maitre, L; Waldmeier, PC1
Antonin, KH; Bieck, PR; Nilsson, E1
Banwart, B; Jones, JD; Miller, TD; Tyce, GM1
Da Prada, M; Haefely, WE; Kettler, R; Schaffner, R; Zürcher, G1
Cramers, CA; de Jong, AP; Haan, E; Kok, RM; Wadman, SK1
Dousa, MK; Tyce, GM1
Bohner, B; Ensor, CR; McCarthy, DA; McLean, JR; Potoczak, D1
Huot, S; Palfreyman, MG; Vitali, P; Wagner, J; Zraika, M1
Aguado, EG; de Yebenes, JG; Mena, MA1
Beers, MF; Hurtig, H; Melvin, G; Scarpa, A; Stern, M1
Hirose, S; Ishimitsu, T1
Fahn, S; Prasad, AL1
Bertrand, A; Weil-Fugazza, J1
Aguirre, J; Armando, I; Barontini, M; Nowicki, S1
Bennett, JP; Schuh, LA1
Kaakkola, S; Wurtman, RJ1
Belakhlef, A; Chaly, T; Dahl, R; Dhawan, V; Eidelberg, D; Ishikawa, T; Mandel, F; Margouleff, C; Robeson, W1
Aguirre, J; Armando, I; Arrizurieta, EE; Barontini, M; Ibarra, FR; Nowicki, S1
Jenner, P; Rose, S; Treseder, SA1
Blandini, F; Fancellu, R; Mangiagalli, A; Martignoni, E; Nappi, G; Pacchetti, C; Samuele, A1
Hainzl, D; Loureiro, AI; Parada, A; Soares-da-Silva, P; Vieira-Coelho, MA1
Buhmann, C; Oechsner, M; Strauss, J; Stuerenburg, HJ1
Fowler, B; Kuhn, W; Müller, T; Woitalla, D1
Almeida, L; Falcão, A; Loureiro, A; Machado, R; Maia, J; Silveira, P; Soares-da-Silva, P; Torrão, L; Vaz-da-Silva, M; Wright, L1
Amirkhani, A; Nilsson, S; Nyholm, L; Nyholm, LM; Törnkvist, A1
Muhlack, S; Müller, T; Przuntek, H; Twiehaus, S; Welnic, J; Woitalla, D1
Allen, RP; Connor, JR; Earley, CJ; Hyland, K1
Kuhn, W; Müller, T1
Muhlack, S; Müller, T1
Area, E; Artuch, R; Cormand, B; Drakaki, K; Garcia-Cazorla, A; Giannakopoulos, A; Kanavakis, E; Orfanou, I; Ormazabal, A; Pons, R; Ribasés, M; Serrano, M; Toma, C; Youroukos, S1
Blau, N; Dill, P; Jakobs, C; Schneider, J; Tekin, M; Thöny, B; Trachsel, D; Weber, P1
Fukui, M; Kang, KS; Wen, Y; Yamabe, N; Zhu, BT1
Chen, PW; Chien, YH; Hwu, WL; Lee, NC; Wang, PC; Wu, JY1
Cardoso, MA; de Carvalho, KA; de Francisco, TM; de Oliveira Vilhena, R; Gasparetto, JC; Guimarães de Francisco, TM; Martins, CA; Pontarolo, R; Ribeiro, RP1
Cao, L; Hao, H; Hao, K; Li, F; Liu, H; Qi, Q; Wang, H1
Bishnoi, P; Charde, SY; Raut, PP1
Asanuma, M; Miyazaki, I1
Akiyama, M; Akiyama, T; Hanaoka, Y; Hayashi, Y; Kobayashi, K; Kubota, M; Nakamura, K; Shibata, T; Tsuyusaki, Y; Yoshinaga, H1
Herrman, L; Kinkel, M; Muhlack, S; Müller, T1

Trials

3 trial(s) available for dihydroxyphenylalanine and 3-methoxytyrosine

ArticleYear
Pharmacokinetic-pharmacodynamic interaction between BIA 3-202, a novel COMT inhibitor, and levodopa/benserazide.
    European journal of clinical pharmacology, 2003, Volume: 59, Issue:8-9

    Topics: Acetophenones; Adolescent; Adult; Antiparkinson Agents; Area Under Curve; Benserazide; Catechol O-Methyltransferase Inhibitors; Cross-Over Studies; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Drug Interactions; Female; Half-Life; Humans; Levodopa; Male; Middle Aged; Tyrosine

2003
Chronic levodopa intake increases levodopa plasma bioavailability in patients with Parkinson's disease.
    Neuroscience letters, 2004, Jun-17, Volume: 363, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Antiparkinson Agents; Area Under Curve; Benserazide; Biological Availability; Dihydroxyphenylalanine; Drug Administration Routes; Drug Administration Schedule; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors; Tyrosine

2004
Homocysteine levels after acute levodopa intake in patients with Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Jul-15, Volume: 24, Issue:9

    Topics: Aged; Analysis of Variance; Antiparkinson Agents; Dihydroxyphenylalanine; Female; Homocysteine; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Severity of Illness Index; Statistics as Topic; Time Factors; Tyrosine

2009

Other Studies

41 other study(ies) available for dihydroxyphenylalanine and 3-methoxytyrosine

ArticleYear
Biochemical and pharmacological properties of a peripherally acting catechol-O-methyltransferase inhibitor entacapone.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Duodenum; Erythrocytes; Homovanillic Acid; In Vitro Techniques; Liver; Male; Nitriles; Rats; Rats, Wistar; Tyrosine

1992
3-O-methyldopa administration does not alter fluorodopa transport into the brain.
    Annals of neurology, 1992, Volume: 31, Issue:6

    Topics: Amino Acid Transport Systems; Amino Acids; Animals; Binding, Competitive; Biological Transport; Blood-Brain Barrier; Brain; Carrier Proteins; Dihydroxyphenylalanine; Macaca fascicularis; Male; Tomography, Emission-Computed; Tyrosine

1992
Routine determination of [18F]-L-6-fluorodopa and its metabolites in blood plasma is essential for accurate positron emission tomography studies.
    Life sciences, 1992, Volume: 50, Issue:4

    Topics: Adsorption; Age Factors; Aluminum Oxide; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Humans; Tomography, Emission-Computed; Tyrosine

1992
Concentrations of tyrosine, L-dihydroxyphenylalanine, dopamine, and 3-O-methyldopa in the cerebrospinal fluid of Parkinson's disease.
    Neuroscience letters, 1991, Jun-24, Volume: 127, Issue:2

    Topics: Aged; Dihydroxyphenylalanine; Dopamine; Humans; Middle Aged; Parkinson Disease; Tyrosine

1991
Simple automated high-performance liquid chromatographic column-switching technique for the measurement of dopa and 3-O-methyldopa in plasma.
    Journal of chromatography, 1990, Sep-14, Volume: 530, Issue:2

    Topics: Animals; Autoanalysis; Benserazide; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Electrochemistry; Humans; In Vitro Techniques; Indicators and Reagents; Male; Rats; Specimen Handling; Tyrosine

1990
Effects of the COMT inhibitor, CGP 28014, on plasma homovanillic acid and O-methylation of exogenous L-dopa in the rat.
    Journal of neural transmission. Supplementum, 1990, Volume: 32

    Topics: Amidines; Animals; Catechol O-Methyltransferase Inhibitors; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Electrochemistry; Female; Homovanillic Acid; Levodopa; Pyridones; Rats; Rats, Inbred Strains; Tyrosine

1990
Effect of the new selective COMT inhibitor CGP 28014 A on the formation of 3-O-methyldopa (3OMD) in plasma of healthy subjects.
    Journal of neural transmission. Supplementum, 1990, Volume: 32

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amidines; Catechol O-Methyltransferase Inhibitors; Dihydroxyphenylalanine; Homovanillic Acid; Humans; Male; Pyridones; Tyrosine

1990
Plasma dopa and feeding.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1989, Volume: 191, Issue:4

    Topics: Animal Feed; Animals; Dihydroxyphenylalanine; Dogs; Dopamine; Eating; Epinephrine; Norepinephrine; Time Factors; Tyrosine

1989
Inhibition of decarboxylase and levels of dopa and 3-O-methyldopa: a comparative study of benserazide versus carbidopa in rodents and of Madopar standard versus Madopar HBS in volunteers.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Administration, Oral; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Brain; Carbidopa; Delayed-Action Preparations; Dihydroxyphenylalanine; Dogs; Dopa Decarboxylase; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrazines; Kidney; Levodopa; Liver; Male; Mice; Rats; Time Factors; Tyrosine

1987
A new method for the determination of L-dopa and 3-O-methyldopa in plasma and cerebrospinal fluid using gas chromatography and electron capture negative ion mass spectrometry.
    Clinica chimica acta; international journal of clinical chemistry, 1988, Jan-15, Volume: 171, Issue:1

    Topics: Acetylation; Adult; Dihydroxyphenylalanine; Esterification; Gas Chromatography-Mass Spectrometry; Humans; Reference Values; Tyrosine

1988
Free and conjugated plasma catecholamines, DOPA and 3-O-methyldopa in humans and in various animal species.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1988, Volume: 188, Issue:4

    Topics: Adult; Animals; Catecholamines; Cats; Cattle; Chlorocebus aethiops; Dihydroxyphenylalanine; Dogs; Female; Guinea Pigs; Humans; Male; Middle Aged; Rabbits; Rats; Rats, Gunn; Rats, Inbred Strains; Species Specificity; Swine; Tyrosine; Ursidae

1988
Effects of L-dopa and L-3-methoxytyrosine on D-methamphetamine-induced motor activity and seizures induced by electroshock.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 143, Issue:4

    Topics: Animals; Brain; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Electroshock; Male; Methamphetamine; Methyl Ethers; Motor Activity; Norepinephrine; Rats; Seizures; Tyrosine

1973
Simultaneous determination of 3,4-dihydroxyphenylalanine, 5-hydroxytryptophan, dopamine, 4-hydroxy-3-methoxyphenylalanine, norepinephrine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5-hydroxyindoleacetic acid in rat cerebrospinal fl
    Journal of neurochemistry, 1982, Volume: 38, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methyltyrosines; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tyrosine

1982
Monoamine metabolites in human cerebrospinal fluid. HPLC/ED method.
    Acta neurologica Scandinavica, 1984, Volume: 69, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Chromatography, High Pressure Liquid; Depression; Dihydroxyphenylalanine; Electrochemistry; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Parkinson Disease; Phenylacetates; Subarachnoid Hemorrhage; Tryptophan; Tyrosine

1984
Simultaneous determination of L-dopa and 3-O-methyldopa in human serum by high-performance liquid chromatography.
    Journal of chromatography, 1984, Dec-12, Volume: 336, Issue:2

    Topics: Adult; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Epinephrine; Humans; Levodopa; Male; Methyltyrosines; Norepinephrine; Parkinson Disease; Tyrosine

1984
Formation of 3-hydroxy-4-methoxyphenylalanine from 3,4-dihydroxyphenylalanine by rat liver homogenate.
    Chemical & pharmaceutical bulletin, 1980, Volume: 28, Issue:7

    Topics: Animals; Catechol O-Methyltransferase; Dihydroxyphenylalanine; In Vitro Techniques; Liver; Male; Methylation; Methyltyrosines; Rats; Tyrosine

1980
A semiautomated method for the rapid determination of dopa: comparison of plasma and erythrocyte-dopa concentration in levodopa-treated patients.
    Biochemical medicine, 1982, Volume: 27, Issue:3

    Topics: Autoanalysis; Dihydroxyphenylalanine; Erythrocytes; Humans; Levodopa; Methyltyrosines; Parkinson Disease; Spectrometry, Fluorescence; Tyrosine

1982
Sympathectomy does not modify the levels of dopa or dopamine in the rat dorsal root ganglion.
    Brain research, 1995, May-29, Volume: 681, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Electrochemistry; Ganglia, Spinal; Guanethidine; Homovanillic Acid; Male; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Tyrosine

1995
A decreased tubular uptake of dopa results in defective renal dopamine production in aged rats.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Biological Transport; Catechol O-Methyltransferase; Dihydroxyphenylalanine; Dopamine; Kidney; Kidney Cortex; Male; Microvilli; Monoamine Oxidase; Norepinephrine; Rats; Rats, Wistar; Regression Analysis; Tyrosine

1995
Suppression of dyskinesias in advanced Parkinson's disease. I. Continuous intravenous levodopa shifts dose response for production of dyskinesias but not for relief of parkinsonism in patients with advanced Parkinson's disease.
    Neurology, 1993, Volume: 43, Issue:8

    Topics: Aged; Antiparkinson Agents; Carbidopa; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Infusions, Intravenous; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Tyrosine

1993
Effects of catechol-O-methyltransferase inhibitors and L-3,4-dihydroxyphenylalanine with or without carbidopa on extracellular dopamine in rat striatum.
    Journal of neurochemistry, 1993, Volume: 60, Issue:1

    Topics: Animals; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Extracellular Space; Male; Nitriles; Nitrophenols; Rats; Rats, Sprague-Dawley; Tolcapone; Tyrosine

1993
Fluorodopa positron emission tomography with an inhibitor of catechol-O-methyltransferase: effect of the plasma 3-O-methyldopa fraction on data analysis.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1996, Volume: 16, Issue:5

    Topics: Adult; Aged; Catechol O-Methyltransferase Inhibitors; Catechols; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Enzyme Inhibitors; Female; Fluorine Radioisotopes; Humans; Kinetics; Male; Middle Aged; Nitriles; Occipital Lobe; Parkinson Disease; Quality Control; Sensitivity and Specificity; Tomography, Emission-Computed; Tyrosine

1996
Demethylation of 3-O-methyldopa in the kidney: a possible source for dopamine in urine.
    The American journal of physiology, 1996, Volume: 270, Issue:5 Pt 2

    Topics: Animals; Catechols; Dihydroxyphenylalanine; Dopamine; Kidney; Kidney Cortex; Kidney Tubules; Male; Methylation; Natriuresis; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tyrosine

1996
The central aromatic amino acid DOPA decarboxylase inhibitor, NSD-1015, does not inhibit L-DOPA-induced circling in unilateral 6-OHDA-lesioned-rats.
    The European journal of neuroscience, 2001, Volume: 13, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Biogenic Monoamines; Brain; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Dopamine Antagonists; Drug Combinations; Enzyme Inhibitors; Haloperidol; Homovanillic Acid; Hydrazines; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Rats; Rats, Wistar; Stereotyped Behavior; Tyrosine

2001
Plasma homocysteine and l-dopa metabolism in patients with Parkinson disease.
    Clinical chemistry, 2001, Volume: 47, Issue:6

    Topics: Antiparkinson Agents; Dihydroxyphenylalanine; Dopamine; Female; Homocysteine; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Tyrosine

2001
BIA 3-202, a novel catechol-O-methyltransferase inhibitor, enhances the availability of L-DOPA to the brain and reduces its O-methylation.
    European journal of pharmacology, 2001, May-18, Volume: 420, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetophenones; Animals; Biological Availability; Brain; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Methylation; Rats; Rats, Wistar; Time Factors; Tyrosine

2001
COMT-inhibition increases serum levels of dihydroxyphenylacetic acid (DOPAC) in patients with advanced Parkinson's disease.
    Journal of neural transmission (Vienna, Austria : 1996), 2002, Volume: 109, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aged, 80 and over; Antiparkinson Agents; Benzophenones; Catechol O-Methyltransferase Inhibitors; Dihydroxyphenylalanine; Disease Progression; Dose-Response Relationship, Drug; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Nitrophenols; Parkinson Disease; Tolcapone; Tyrosine

2002
3-OMD and homocysteine plasma levels in parkinsonian patients.
    Journal of neural transmission (Vienna, Austria : 1996), 2002, Volume: 109, Issue:2

    Topics: Dihydroxyphenylalanine; Female; Homocysteine; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Tyrosine

2002
Interference of the electrospray voltage on chromatographic separations using porous graphitic carbon columns.
    Journal of mass spectrometry : JMS, 2004, Volume: 39, Issue:2

    Topics: Chromatography, Liquid; Dihydroxyphenylalanine; Dopamine; Electrochemistry; Graphite; Norepinephrine; Spectrometry, Mass, Electrospray Ionization; Tyrosine

2004
Abnormally increased CSF 3-Ortho-methyldopa (3-OMD) in untreated restless legs syndrome (RLS) patients indicates more severe disease and possibly abnormally increased dopamine synthesis.
    Sleep medicine, 2009, Volume: 10, Issue:1

    Topics: Adult; Aged; Biomarkers; Circadian Rhythm; Dihydroxyphenylalanine; Dopamine; Female; Humans; Linear Models; Male; Middle Aged; Restless Legs Syndrome; Severity of Illness Index; Spinal Puncture; Tyrosine; Tyrosine 3-Monooxygenase

2009
Peripheral COMT inhibition prevents levodopa associated homocysteine increase.
    Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antiparkinson Agents; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Delayed-Action Preparations; Dihydroxyphenylalanine; Enzyme Inhibitors; Female; Homocysteine; Humans; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Time Factors; Tyrosine

2009
Tyrosine hydroxylase deficiency in three Greek patients with a common ancestral mutation.
    Movement disorders : official journal of the Movement Disorder Society, 2010, Jun-15, Volume: 25, Issue:8

    Topics: Child, Preschool; Dihydroxyphenylalanine; DNA Mutational Analysis; Greece; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Leucine; Metabolic Diseases; Methoxyhydroxyphenylglycol; Mutation; Proline; Tyrosine; Tyrosine 3-Monooxygenase; Young Adult

2010
Pyridoxal phosphate-responsive seizures in a patient with cerebral folate deficiency (CFD) and congenital deafness with labyrinthine aplasia, microtia and microdontia (LAMM).
    Molecular genetics and metabolism, 2011, Volume: 104, Issue:3

    Topics: Base Sequence; Child; Codon, Nonsense; Congenital Abnormalities; Congenital Microtia; Dihydroxyphenylalanine; DNA Primers; Ear; Ear, Inner; Electroencephalography; Epilepsy; Fibroblast Growth Factor 3; Folate Receptor 1; Folic Acid Deficiency; Humans; Levodopa; Male; Molecular Sequence Data; Pyridoxal Phosphate; Radiography; Sequence Analysis, DNA; Skull; Syndrome; Tooth Abnormalities; Tyrosine

2011
Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration.
    Brain research, 2013, Feb-25, Volume: 1497

    Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Antiparkinson Agents; Carbidopa; Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Disease Models, Animal; Excitatory Amino Acid Agonists; Fluoresceins; Glial Fibrillary Acidic Protein; Hippocampus; Hydroxybenzoates; In Vitro Techniques; Kainic Acid; Levodopa; Male; Methylation; Mice; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Reserpine; Time Factors; Tyrosine

2013
Diagnosis of aromatic L-amino acid decarboxylase deficiency by measuring 3-O-methyldopa concentrations in dried blood spots.
    Clinica chimica acta; international journal of clinical chemistry, 2014, Apr-20, Volume: 431

    Topics: Amino Acid Metabolism, Inborn Errors; Aromatic-L-Amino-Acid Decarboxylases; Calibration; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dried Blood Spot Testing; Humans; Infant; Infant, Newborn; Neonatal Screening; Quality Control; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry; Tyrosine

2014
Simultaneous determination of levodopa, carbidopa, entacapone, tolcapone, 3-O-methyldopa and dopamine in human plasma by an HPLC-MS/MS method.
    Bioanalysis, 2015, Volume: 7, Issue:2

    Topics: Benzophenones; Blood Chemical Analysis; Carbidopa; Catechols; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Humans; Levodopa; Nitriles; Nitrophenols; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry; Tolcapone; Tyrosine

2015
Salvianolic acid B as a substrate and weak catechol-O-methyltransferase inhibitor in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 2015, Volume: 45, Issue:9

    Topics: Animals; Benzofurans; Benzophenones; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Dihydroxyphenylalanine; Kinetics; Levodopa; Male; Metabolome; Methylation; Nitrophenols; Organ Specificity; Rats, Sprague-Dawley; Reproducibility of Results; Substrate Specificity; Tolcapone; Tyrosine

2015
Simultaneous estimation of levodopa, carbidopa and 3-oxymethyldopa in rat plasma using HPLC-ECD.
    Biomedical chromatography : BMC, 2016, Volume: 30, Issue:10

    Topics: Animals; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Electrochemical Techniques; Levodopa; Limit of Detection; Male; Rats; Rats, Wistar; Tyrosine

2016
3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of L-DOPA.
    BMC neuroscience, 2016, 07-25, Volume: 17, Issue:1

    Topics: Animals; Astrocytes; Catechol O-Methyltransferase Inhibitors; Catechols; Cells, Cultured; Corpus Striatum; Dihydroxyphenylalanine; Dopamine Agents; Dopaminergic Neurons; Dose-Response Relationship, Drug; Glutathione; Levodopa; Mesencephalon; Neuroprotection; Neuroprotective Agents; Nitriles; Rats, Sprague-Dawley; Tyrosine

2016
Simultaneous measurement of monoamine metabolites and 5-methyltetrahydrofolate in the cerebrospinal fluid of children.
    Clinica chimica acta; international journal of clinical chemistry, 2017, Volume: 465

    Topics: Aromatic-L-Amino-Acid Decarboxylases; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dystonic Disorders; Fluorescence; Folate Receptor 1; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Limit of Detection; Methoxyhydroxyphenylglycol; Neuroaxonal Dystrophies; Reference Values; Reproducibility of Results; Tetrahydrofolates; Tyrosine

2017
Levodopa, placebo and rotigotine change biomarker levels for oxidative stress.
    Neurological research, 2017, Volume: 39, Issue:5

    Topics: Aged; Analysis of Variance; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dipeptides; Dopamine Agents; Electrochemical Techniques; Female; Homocysteine; Humans; Levodopa; Male; Middle Aged; Oxidative Stress; Parkinson Disease; Tetrahydronaphthalenes; Thiophenes; Time Factors; Tyrosine

2017