dihydroxyphenylalanine has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 33 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (24.24) | 18.7374 |
1990's | 14 (42.42) | 18.2507 |
2000's | 9 (27.27) | 29.6817 |
2010's | 2 (6.06) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Aigner, TG; Cohen, RM; Doudet, DJ; McLellan, CA | 1 |
Björklund, A; Brundin, P; Gustavii, B; Langston, JW; Lindvall, O; Rehncrona, S; Snow, B; Tetrud, J; Widner, H | 1 |
Björklund, A; Bloomfield, PM; Brooks, DJ; Brundin, P; Leenders, KL; Lindvall, O; Marsden, CD; Rehncrona, S; Sawle, GV; Widner, H | 1 |
Barrio, JR; Hoffman, JM; Melega, WP; Phelps, ME; Schneider, JS | 1 |
Barrio, JR; Hoffman, JM; Huang, SC; Mazziotta, JC; Melega, WP; Phelps, ME; Satyamurthy, N; Schneider, JS; Yu, DC | 1 |
Carlsson, A; Clark, D; Fornstedt, B; Pileblad, E | 1 |
Eldrup, E; Fog, R; Pakkenberg, B; Pakkenberg, H | 1 |
Hirata, Y; Nagatsu, T | 2 |
Hamasaki, D; Ishibashi, T; Tucker, G; Wong, C | 1 |
Boyes, BE; Cumming, P; Martin, WR; McGeer, EG | 1 |
Burns, RS; Chirakal, R; Chiueh, CC; Firnau, G; Garnett, ES; Kopin, IJ; Nahmias, C | 1 |
Enz, A; Frick, W; Hefti, F | 1 |
Akunne, HC; Cooke, LW; Davis, MD; DeMattos, SB; Georgic, LM; MacKenzie, RG; Rugsley, TA; Shih, YH; van Leeuwen, DH; Whetzel, SZ | 1 |
Bonuccelli, U; Fariello, R; Garant, DS; Maggio, R | 1 |
Calne, DB; Langston, JW; Schulzer, M; Snow, BJ; Tetrud, JW; Vingerhoets, FJ | 1 |
Lin, JY; Mai, LM; Pan, JT | 1 |
Bédard, PJ; Blanchet, PJ; Gomez-Mancilla, B | 1 |
Schneider, JS | 1 |
Barrio, JR; Huang, SC; Phelps, ME | 1 |
Aigner, TA; Chan, GL; Doudet, DJ; Holden, JE; McGeer, EG; Ruth, TJ; Wyatt, RJ | 1 |
Carson, RE; Cohen, RM; Doudet, DJ; Wyatt, RJ | 1 |
Barrio, JR; DeLanney, LE; Farahani, KF; Huang, SC; Irwin, I; Langston, JW; Phelps, ME; Satyamurthy, N; Shoghi-Jadid, K; Stout, DB; Togaski, DM; Yee, RE | 1 |
Aebischer, P; Bloch, J; Brown, WD; Carvey, P; Chen, EY; Chu, Y; Déglon, N; Emborg, ME; Hantraye, P; Holden, JE; Kordower, JH; Leventhal, L; Ling, Z; Ma, SY; McBride, J; Palfi, S; Pyzalski, R; Roitberg, BZ; Taylor, MD; Trono, D | 1 |
Hadjiconstantinou, M; Neff, NH; Wemlinger, TA | 1 |
Agid, Y; Faucheux, BA; Hartmann, A; Hirsch, EC; Hunot, S; Kikly, K; Mouatt-Prigent, A; Ruberg, M; Troadec, JD | 1 |
Bottlaender, M; Condé, F; Coulon, C; Dollé, F; Frouin, V; Fuseau, C; Grégoire, MC; Hantraye, P; Hinnen, F; Poyot, T | 1 |
Hirata, Y; Kiuchi, K; Nagatsu, T | 1 |
Barrio, JR; Delanney, LE; Delfani, K; Farahani, KF; Huang, SC; Irwin, I; Janson, AM; Langston, JW; Milonas, C; Phelps, ME; Satyamurthy, N; Shoghi-Jadid, K; Stout, DB; Togasaki, DM; Yee, RE | 1 |
Brotchie, JM; Fox, SH; Johnston, TH; Millan, MJ; Visanji, NP | 1 |
Kostrzewa, RM | 1 |
Bakay, RA; Deogaonkar, M; Lieu, CA; Subramanian, T | 1 |
Alter, H; Domanskyi, A; Gass, P; Geissler, C; Parlato, R; Schober, A; Schütz, G; Vinnikov, IA; Vogt, MA | 1 |
3 review(s) available for dihydroxyphenylalanine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Article | Year |
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DOPA-induced "peak dose" dyskinesia: clues implicating D2 receptor-mediated mechanisms using dopaminergic agonists in MPTP monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dihydroxyphenylalanine; Dopamine Agonists; Dyskinesia, Drug-Induced; Haplorhini; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1995 |
Biological imaging and the molecular basis of dopaminergic diseases.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aromatic-L-Amino-Acid Decarboxylases; Brain; Cell Count; Dihydroxyphenylalanine; Dopamine; Haplorhini; Humans; Kinetics; Parkinson Disease; Putamen; Rodentia; Substantia Nigra; Tomography, Emission-Computed | 1997 |
Evolution of neurotoxins: from research modalities to clinical realities.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic Agents; Animals; Benzylamines; Botulinum Toxins, Type A; Dihydroxyphenylalanine; Dihydroxytryptamines; Glutamic Acid; Humans; Models, Animal; Nerve Growth Factor; Neurosciences; Neurotoxins; Oxidopamine; Terminology as Topic | 2009 |
1 trial(s) available for dihydroxyphenylalanine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Article | Year |
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Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adult; Caudate Nucleus; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Fetal Tissue Transplantation; Humans; Immunosuppression Therapy; Levodopa; Male; Mesencephalon; Motor Activity; Parkinson Disease, Secondary; Putamen; Stereotaxic Techniques; Time Factors; Tomography, Emission-Computed | 1992 |
29 other study(ies) available for dihydroxyphenylalanine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Article | Year |
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Positron emission tomography with 18F-dopa: interpretation and biological correlates in nonhuman primates.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Carbidopa; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Macaca mulatta; Methoxyhydroxyphenylglycol; Parkinson Disease, Secondary; Receptors, Dopamine; Tomography, Emission-Computed | 1992 |
Transplantation of fetal dopamine neurons in Parkinson's disease: PET [18F]6-L-fluorodopa studies in two patients with putaminal implants.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Brain Tissue Transplantation; Caudate Nucleus; Dihydroxyphenylalanine; Dopamine; Fetal Tissue Transplantation; Humans; Mesencephalon; Models, Biological; Parkinson Disease; Parkinson Disease, Secondary; Putamen; Tomography, Emission-Computed | 1992 |
6-[18F]fluoro-L-dopa metabolism in MPTP-treated monkeys: assessment of tracer methodologies for positron emission tomography.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Macaca nemestrina; Male; Tomography, Emission-Computed | 1991 |
6-[18F]fluoro-L-dopa probes dopamine turnover rates in central dopaminergic structures.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Fluorescent Dyes; Fluorine Radioisotopes; Macaca nemestrina; Male; Parkinson Disease; Parkinson Disease, Secondary; Putamen; Tomography, Emission-Computed | 1990 |
Acute effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on dopamine metabolism in mouse and rat striatum.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 5-Hydroxytryptophan; Animals; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Pyridines; Rats; Rats, Inbred Strains; Species Specificity; Time Factors; Tryptophan; Tyrosine | 1985 |
The effect of MPTP on uridine uptake in murine nerve cells.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Male; Mice; Mice, Inbred Strains; Organ Specificity; Pyridines; Reference Values; RNA; Selegiline; Substantia Nigra; Uridine | 1988 |
Inhibition of tyrosine hydroxylation in tissue slices of the rat striatum by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Hydroxylation; In Vitro Techniques; Male; Nomifensine; Nucleus Accumbens; Pyridines; Rats; Rats, Inbred Strains; Sulpiride; Tyrosine; Tyrosine 3-Monooxygenase | 1985 |
Responses of the pigmented rabbit retina to NMPTP, a chemical inducer of parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dihydroxyphenylalanine; Dopamine; Electroretinography; Female; Inclusion Bodies; Male; Microscopy, Electron; Pyridines; Rabbits; Retina | 1985 |
Determination of plasma [18F]-6-fluorodopa during positron emission tomography: elimination and metabolism in carbidopa treated subjects.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Age Factors; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dystonia; Humans; Kinetics; Metabolic Clearance Rate; Parkinson Disease; Pyridines; Tomography, Emission-Computed | 1986 |
Determination and visualization of damage to striatal dopaminergic terminals in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism by [18F]-labeled 6-fluoro-L-dopa and positron emission tomography.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dihydroxyphenylalanine; Macaca mulatta; Parkinson Disease, Secondary; Pyridines; Receptors, Dopamine; Tomography, Emission-Computed | 1987 |
Inhibition of tyrosine hydroxylation in rat striatal tissue slices by 1-methyl-4-phenylpyridinium ion.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dihydroxyphenylalanine; Hydroxylation; In Vitro Techniques; Male; Monoamine Oxidase; Pargyline; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Tyrosine | 1985 |
Acute administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) reduces dopamine and serotonin but accelerates norepinephrine metabolism in the rat brain. Effect of chronic pretreatment with MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Brain Chemistry; Cattle; Dihydroxyphenylalanine; Dopamine; Male; Norepinephrine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Serotonin; Time Factors | 1984 |
CI-1007, a dopamine partial agonist and potential antipsychotic agent. I. Neurochemical effects.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 4-Butyrolactone; Acetylcholine; Adenylyl Cyclases; Animals; Antipsychotic Agents; Autoreceptors; CHO Cells; Cricetinae; Dihydroxyphenylalanine; Dopamine; Dopamine Agonists; Guinea Pigs; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Serotonin | 1995 |
Motor expression of kainic acid seizures is attenuated by dopamine depletion in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Electric Stimulation; Homovanillic Acid; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Seizures | 1994 |
Positron emission tomographic evidence for progression of human MPTP-induced dopaminergic lesions.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adult; Aged; Aged, 80 and over; Corpus Striatum; Dihydroxyphenylalanine; Disease Progression; Dopamine; Female; Humans; Male; Middle Aged; Parkinson Disease, Secondary; Substantia Nigra; Syndrome; Tomography, Emission-Computed | 1994 |
Effects of systemic administration of 6-hydroxydopamine, 6-hydroxydopa and 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine (MPTP) on tuberoinfundibular dopaminergic neurons in the rat.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Arcuate Nucleus of Hypothalamus; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Neurons; Oxidopamine; Rats | 1993 |
Preservation of autoreceptor-mediated increases in dopamine synthesis in aged mice with experimentally-induced parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Autoreceptors; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Haloperidol; Male; Mice; Mice, Inbred C57BL; Neurons; Parkinson Disease, Secondary; Tyrosine 3-Monooxygenase | 1997 |
6-[18F]Fluoro-L-DOPA PET studies of the turnover of dopamine in MPTP-induced parkinsonism in monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Macaca fascicularis; Macaca mulatta; Parkinson Disease, Secondary; Reference Values; Tomography, Emission-Computed | 1998 |
Opiate receptor avidity is reduced bilaterally in rhesus monkeys unilaterally lesioned with MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Basal Ganglia; Brain; Cerebellum; Cerebral Cortex; Dihydroxyphenylalanine; Fluorine Radioisotopes; Functional Laterality; Infusions, Parenteral; Limbic System; Macaca mulatta; Naltrexone; Narcotic Antagonists; Organ Specificity; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tomography, Emission-Computed | 1999 |
Nigrostriatal reduction of aromatic L-amino acid decarboxylase activity in MPTP-treated squirrel monkeys: in vivo and in vitro investigations.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Corpus Striatum; Dihydroxyphenylalanine; Dopamine Agents; Female; Male; Saimiri; Substantia Nigra; Tomography, Emission-Computed | 2000 |
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Antigens, CD; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Female; Gene Expression; Genetic Therapy; Genetic Vectors; Glial Cell Line-Derived Neurotrophic Factor; Lentivirus; Macaca mulatta; Neostriatum; Nerve Degeneration; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Parkinson Disease; Parkinsonian Disorders; Psychomotor Performance; Substantia Nigra; Tyrosine 3-Monooxygenase | 2000 |
SCH 23390 enhances exogenous L-DOPA decarboxylation in nigrostriatal neurons.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic-L-Amino-Acid Decarboxylases; Benzazepines; Corpus Striatum; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Dopamine Antagonists; Levodopa; Male; Mice; Substantia Nigra | 2000 |
Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis; Caspase 8; Caspase 9; Caspases; Dihydroxyphenylalanine; Disease Models, Animal; Humans; Locus Coeruleus; Male; Mice; Neurons; Parkinson Disease; Rats; Substantia Nigra | 2001 |
Anatomic and biochemical correlates of the dopamine transporter ligand 11C-PE2I in normal and parkinsonian primates: comparison with 6-[18F]fluoro-L-dopa.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Brain Chemistry; Carbon Radioisotopes; Carrier Proteins; Caudate Nucleus; Cerebellum; Corpus Striatum; Dihydroxyphenylalanine; Dopamine Plasma Membrane Transport Proteins; Fluorine Radioisotopes; Kinetics; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nortropanes; Papio; Parkinson Disease, Secondary; Putamen; Reserpine; Substantia Nigra; Tomography, Emission-Computed; Tyrosine 3-Monooxygenase | 2001 |
Manganese mimics the action of 1-methyl-4-phenylpyridinium ion, a dopaminergic neurotoxin, in rat striatal tissue slices.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Glycolysis; Hydroxylation; Lactic Acid; Male; Manganese; Manganese Poisoning; MPTP Poisoning; Neostriatum; Neurotoxins; Rats; Rats, Wistar; Tyrosine; Tyrosine 3-Monooxygenase | 2001 |
Novel observations with FDOPA-PET imaging after early nigrostriatal damage.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Female; Fluorine Radioisotopes; Male; Neural Pathways; Neurotoxins; Parkinsonian Disorders; Saimiri; Substantia Nigra; Tomography, Emission-Computed | 2001 |
Alpha1-adrenoceptors mediate dihydroxyphenylalanine-induced activity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaques.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic alpha-Antagonists; Animals; Benserazide; Brain Injuries; Dihydroxyphenylalanine; Female; Levodopa; Macaca fascicularis; Male; Motor Activity; Prazosin; Receptors, Adrenergic, alpha | 2009 |
Dyskinesias do not develop after chronic intermittent levodopa therapy in clinically hemiparkinsonian rhesus monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Behavior, Animal; Carotid Arteries; Conditioning, Operant; Corpus Striatum; Dihydroxyphenylalanine; Dopamine Agents; Dyskinesia, Drug-Induced; Dystonia; Female; Injections, Intravenous; Levodopa; Macaca mulatta; MPTP Poisoning; Parkinson Disease, Secondary; Psychomotor Performance; Radionuclide Imaging; Radiopharmaceuticals; Substantia Nigra | 2011 |
Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Dopamine Agents; Gene Deletion; Gene Expression Regulation; Mice; Mice, Knockout; Neurons; Parkinson Disease; Pol1 Transcription Initiation Complex Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; TOR Serine-Threonine Kinases; Tyrosine 3-Monooxygenase | 2011 |