Compounds > dihydrouracil

dihydrouracil and uridine

dihydrouracil has been researched along with uridine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's2 (20.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Engelbrecht, C; Yngner, T1
Kraal, I; Lankelma, J; Laurensse, E; Leyva, A; Peters, GJ; Pinedo, HM; van Groeningen, CJ1
Allerhand, A; Komoroski, RA1
Anderson, DC; Cretton, EM; el Kouni, MH; Kidd, LB; McClure, HM; Sommadossi, JP1
Kulik, W; van Cruchten, A; van Kuilenburg, AB; van Lenthe, H1
Beumer, JH; Covey, JM; Egorin, MJ; Eiseman, JL; Joseph, E1
Beumer, JH; Covey, JM; D'argenio, DZ; Egorin, MJ; Eiseman, JL; Joseph, E; Parker, RS1
Hirano, N; Nakamura, A; Suzuki, T; Tanaka, I; Tanaka, Y; Yamashita, K; Yao, M; Yu, F1
Beijnen, JH; Cats, A; de Vries, N; Guchelaar, HJ; Henricks, LM; Huitema, ADR; Jacobs, BAW; Meulendijks, D; Pluim, D; Rosing, H; Schellens, JHM; van den Broek, D1
Bukhari, SNA; Ejaz, H; Elsherif, MA; Janković, N1

Trials

1 trial(s) available for dihydrouracil and uridine

ArticleYear
Food-effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:12

    Topics: Adult; Biomarkers; Cross-Over Studies; Dihydrouracil Dehydrogenase (NADP); Fasting; Female; Food; Healthy Volunteers; Humans; Male; Middle Aged; Uracil; Uridine

2018

Other Studies

9 other study(ies) available for dihydrouracil and uridine

ArticleYear
Metabolism of uridine and determination of liver ribonucleic acid synthesis in developing and adult mice.
    The International journal of biochemistry, 1985, Volume: 17, Issue:4

    Topics: Aging; Alanine; Animals; beta-Alanine; Liver; Male; Mice; Orotic Acid; RNA; Tritium; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate

1985
Effect of pyrimidine nucleosides on body temperatures of man and rabbit in relation to pharmacokinetic data.
    Pharmaceutical research, 1987, Volume: 4, Issue:2

    Topics: Animals; beta-Alanine; Body Temperature Regulation; Cytidine; Dose-Response Relationship, Drug; Fever; Humans; Pyrimidine Nucleotides; Rabbits; Uracil; Uridine; Uridine Phosphorylase

1987
Observation of resonances from some minor bases in the natural-abundance carbon-13 nuclear magnetic resonance spectrum of unfractionated yeast transfer ribonucleic acid. Evidence for fast internal motion of the dihydrouracil rings.
    Biochemistry, 1974, Jan-15, Volume: 13, Issue:2

    Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Fourier Analysis; Inosine; Magnesium; Magnetic Resonance Spectroscopy; Nucleotides; Pseudouridine; Ribose; RNA, Transfer; Saccharomyces cerevisiae; Thymine; Uracil; Uridine

1974
Effects of 5-benzylacyclouridine, an inhibitor of uridine phosphorylase, on the pharmacokinetics of uridine in rhesus monkeys: implications for chemotherapy.
    Cancer chemotherapy and pharmacology, 1995, Volume: 37, Issue:1-2

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Macaca mulatta; Uracil; Uridine; Uridine Phosphorylase

1995
Quantification of 5,6-dihydrouracil by HPLC-electrospray tandem mass spectrometry.
    Clinical chemistry, 2004, Volume: 50, Issue:1

    Topics: Chromatography, High Pressure Liquid; Humans; Infant, Newborn; Spectrometry, Mass, Electrospray Ionization; Uracil; Uridine

2004
Quantitative determination of zebularine (NSC 309132), a DNA methyltransferase inhibitor, and three metabolites in murine plasma by high-performance liquid chromatography coupled with on-line radioactivity detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Feb-02, Volume: 831, Issue:1-2

    Topics: Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cytidine; DNA Modification Methylases; Drug Stability; Male; Mice; Mice, Inbred Strains; Online Systems; Reproducibility of Results; Sensitivity and Specificity; Specific Pathogen-Free Organisms; Spectrophotometry, Ultraviolet; Uracil; Uridine

2006
A mass balance and disposition study of the DNA methyltransferase inhibitor zebularine (NSC 309132) and three of its metabolites in mice.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Oct-01, Volume: 12, Issue:19

    Topics: Animals; Chromatography, High Pressure Liquid; Cytidine; DNA Modification Methylases; Male; Mice; Uracil; Uridine

2006
Molecular basis of dihydrouridine formation on tRNA.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Dec-06, Volume: 108, Issue:49

    Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Biocatalysis; Crystallography, X-Ray; Electrophoresis, Polyacrylamide Gel; Flavin Mononucleotide; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Oxidation-Reduction; Oxidoreductases; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; RNA, Transfer; Sequence Homology, Amino Acid; Thermus thermophilus; Uracil; Uridine

2011
Synthesis and Characterization of Dihydrouracil Analogs Utilizing Biginelli Hybrids.
    Molecules (Basel, Switzerland), 2022, May-04, Volume: 27, Issue:9

    Topics: Uracil; Uridine

2022