dihydrouracil has been researched along with capecitabine in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Beijnen, JH; Bosch, TM; Jörger, M; Schellens, JH; Sparidans, RW | 1 |
| Gelderblom, H; Guchelaar, HJ; Maring, JG; Opdam, F; van Kuilenburg, AB; van Staveren, MC | 1 |
| Aliev, A; Beijnen, JH; Cats, A; de Boer, A; de Vries, N; Deenen, MJ; Henricks, LM; Jacobs, BAW; Mandigers, CMPW; Meulendijks, D; Rosing, H; Schellens, JHM; Soesan, M; van Werkhoven, E | 1 |
| Beijnen, JH; de Vries, N; Deenen, MJ; Jacobs, BAW; Koopman, M; Rosing, H; Samim, M; Schellens, JHM; Snoeren, N; van Hillegersberg, R | 1 |
| Ciccolini, J; De Victor, B; Hilaire, V; Krache, A; Lacarelle, B; Lucas, M; Marin, C; Palmaro, C; Quaranta, S; Solas, C; Ugdonne, R | 1 |
| Abarca-Zabalía, J; García-Alfonso, P; García-González, X; Kaczmarczyk, B; López-Fernández, LA; Pachón, V; Robles, L; Salvador-Martín, S; Sanjurjo-Sáez, M; Thomas, F; Vaz, Á | 1 |
| Broeren, MAC; Brunsveld, L; Deenen, MJ; Hanrath, MA; Lapré, C; Scharnhorst, V; Streng, AS; van de Kerkhof, D; van den Broek, R; van den Wildenberg, SAH; van Dongen, JLJ | 1 |
1 trial(s) available for dihydrouracil and capecitabine
| Article | Year |
|---|---|
The impact of liver resection on the dihydrouracil:uracil plasma ratio in patients with colorectal liver metastases.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Colorectal Neoplasms; Female; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Uracil | 2018 |
6 other study(ies) available for dihydrouracil and capecitabine
| Article | Year |
|---|---|
Liquid chromatography-tandem mass spectrometric assay for the analysis of uracil, 5,6-dihydrouracil and beta-ureidopropionic acid in urine for the measurement of the activities of the pyrimidine catabolic enzymes.
Topics: beta-Alanine; Biological Assay; Calibration; Capecitabine; Case-Control Studies; Child; Child, Preschool; Chromatography, Liquid; Deoxycytidine; Enzymes; Female; Fluorouracil; Humans; Infant, Newborn; Male; Pyrimidines; Spectrometry, Mass, Electrospray Ionization; Uracil | 2006 |
Influence of metastatic disease on the usefulness of uracil pharmacokinetics as a screening tool for DPD activity in colorectal cancer patients.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Humans; Neoplasm Metastasis; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Uracil | 2015 |
Pretreatment serum uracil concentration as a predictor of severe and fatal fluoropyrimidine-associated toxicity.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Antimetabolites, Antineoplastic; Biomarkers; Capecitabine; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Genotype; Hospitalization; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Neoplasms; Pharmacogenomic Testing; Pharmacogenomic Variants; Phenotype; Predictive Value of Tests; Prospective Studies; Thymidylate Synthase; Uracil; Young Adult | 2017 |
A Simple and Rapid UPLC-UV Method for Detecting DPD Deficiency in Patients With Cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers; Capecitabine; Chromatography, High Pressure Liquid; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Spectrophotometry, Ultraviolet; Uracil | 2020 |
New DPYD variants causing DPD deficiency in patients treated with fluoropyrimidine.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Computer Simulation; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Humans; Male; Middle Aged; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Retrospective Studies; Uracil | 2020 |
Quantification of uracil, dihydrouracil, thymine and dihydrothymine for reliable dihydropyrimidine dehydrogenase (DPD) phenotyping critically depend on blood and plasma storage conditions.
Topics: Biomarkers; Capecitabine; Chromatography, Liquid; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Humans; Tandem Mass Spectrometry; Thymine; Uracil | 2022 |