dihydrotetrabenazine has been researched along with methylphenidate in 14 studies
| Studies (dihydrotetrabenazine) | Trials (dihydrotetrabenazine) | Recent Studies (post-2010) (dihydrotetrabenazine) | Studies (methylphenidate) | Trials (methylphenidate) | Recent Studies (post-2010) (methylphenidate) |
|---|---|---|---|---|---|
| 234 | 4 | 60 | 7,783 | 1,698 | 2,693 |
| Protein | Taxonomy | dihydrotetrabenazine (IC50) | methylphenidate (IC50) |
|---|---|---|---|
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.061 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.083 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 5.1 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.079 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (71.43) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kilbourn, MR; Kuszpit, K; Sherman, P | 1 |
| Chan, G; Holden, JE; Krzywinski, M; Ruth, TJ; Sossi, V; Stoessl, AJ | 1 |
| Kilbourn, MR; Kuszpit, K; Sherman, PS | 1 |
| Fleckenstein, AE; Hanson, GR; Riddle, EL; Sandoval, V | 1 |
| Calne, DB; De La Fuente-Fernández, R; Furtado, S; Furukawa, Y; Guttman, M; Lee, CS; Ruth, TJ; Stoessl, AJ | 1 |
| Kilbourn, MR | 1 |
| Desmond, TJ; Frey, KA; Kemmerer, ES; Kilbourn, MR; Sherman, PS | 1 |
| Adams, JR; Calne, DB; Farrer, M; Gasser, T; Lee, CS; Mak, E; Mckenzie, J; Ruth, TJ; Schulzer, M; Sossi, V; Stoessl, AJ; Strongosky, A; Uitti, RJ; van Netten, H; Wszolek, ZK | 1 |
| de la Fuente-Fernandez, R; Mak, E; Ruth, TJ; Schulzer, M; Sossi, V; Stoessl, AJ; Troiano, AR | 1 |
| Albin, RL; Frey, KA; Kilbourn, MR; Koeppe, RA; Nichols, T; Wernette, K; Zhuang, W | 1 |
| de la Fuente-Fernandez, R; Mak, E; McCormick, S; McKenzie, J; Ruth, TJ; Schulzer, M; Sossi, V; Stoessl, AJ; Troiano, AR | 1 |
| Rehavi, M; Simchon, Y; Weizman, A | 1 |
| Au, WL; Calne, DB; Cragg, J; de la Fuente-Fernández, R; Kuramoto, L; Lee, CS; Mak, E; McCormick, S; McKenzie, J; Ramachandiran, N; Ruth, TJ; Schulzer, M; Sossi, V; Stoessl, AJ | 1 |
| Aasly, JO; Armaly, J; Furay, AR; Hasegawa, K; Leverenz, JB; Shi, M; Sossi, V; Stoessl, AJ; Uitti, RJ; Wang, Y; Wszolek, ZK; Yokoyama, T; Zabetian, CP; Zhang, J | 1 |
14 other study(ies) available for dihydrotetrabenazine and methylphenidate
| Article | Year |
|---|---|
Rapid and differential losses of in vivo dopamine transporter (DAT) and vesicular monoamine transporter (VMAT2) radioligand binding in MPTP-treated mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Carbon Radioisotopes; Carrier Proteins; Cerebellum; Cerebral Cortex; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Hippocampus; Hypothalamus; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuropeptides; Neurotransmitter Agents; Radioligand Assay; Tetrabenazine; Tissue Distribution; Tritium; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2000 |
Analysis of four dopaminergic tracers kinetics using two different tissue input function methods.
Topics: Adult; Aged; Benzazepines; Carrier Proteins; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Middle Aged; Models, Biological; Nerve Tissue Proteins; Neuropeptides; Raclopride; Receptors, Dopamine D1; Tetrabenazine; Vesicular Biogenic Amine Transport Proteins | 2000 |
In vivo measures of dopaminergic radioligands in the rat brain: equilibrium infusion studies.
Topics: Animals; Binding, Competitive; Brain; Carbon Radioisotopes; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Infusion Pumps; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Nerve Tissue Proteins; Neurons; Neuropeptides; Radioligand Assay; Rats; Rats, Sprague-Dawley; Tetrabenazine; Tritium; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2002 |
Methylphenidate redistributes vesicular monoamine transporter-2: role of dopamine receptors.
Topics: Animals; Binding, Competitive; Blotting, Western; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Neuropeptides; Protein Transport; Rats; Receptors, Dopamine; Subcellular Fractions; Synaptosomes; Tetrabenazine; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2002 |
VMAT2 binding is elevated in dopa-responsive dystonia: visualizing empty vesicles by PET.
Topics: Adolescent; Adult; Carbon Radioisotopes; Corpus Striatum; Cytoplasmic Vesicles; Dopamine; Dopamine Agents; Dystonic Disorders; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Middle Aged; Neuropeptides; Parkinson Disease; Raclopride; Tetrabenazine; Tomography, Emission-Computed; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2003 |
Long-term reproducibility of in vivo measures of specific binding of radioligands in rat brain.
Topics: Aging; Animals; Brain; Carbon Radioisotopes; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Nerve Tissue Proteins; Protein Binding; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Sex Factors; Tetrabenazine; Time Factors; Tritium; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2004 |
Differential effects of scopolamine on in vivo binding of dopamine transporter and vesicular monoamine transporter radioligands in rat brain.
Topics: Animals; Binding, Competitive; Brain; Brain Chemistry; Dopamine Plasma Membrane Transport Proteins; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Muscarinic Antagonists; Nerve Tissue Proteins; Neuropeptides; Radioligand Assay; Rats; Scopolamine; Tetrabenazine; Tritium; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2004 |
PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation.
Topics: Adult; Age Factors; Aged; Brain; Carbon Radioisotopes; Carboxy-Lyases; Case-Control Studies; Dopamine Plasma Membrane Transport Proteins; Fluorine Radioisotopes; Humans; Image Processing, Computer-Assisted; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Levodopa; Methylphenidate; Middle Aged; Mutation; Parkinson Disease; Phenotype; Positron-Emission Tomography; Protein Serine-Threonine Kinases; Radiopharmaceuticals; Receptors, Dopamine D2; Regression Analysis; Tetrabenazine | 2005 |
PET demonstrates reduced dopamine transporter expression in PD with dyskinesias.
Topics: Caudate Nucleus; Dopamine Plasma Membrane Transport Proteins; Dyskinesias; Female; Humans; Logistic Models; Male; Methylphenidate; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Putamen; Radiopharmaceuticals; Tetrabenazine | 2009 |
Striatal [11C]dihydrotetrabenazine and [11C]methylphenidate binding in Tourette syndrome.
Topics: Adolescent; Adult; Binding, Competitive; Carbon Radioisotopes; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Humans; Male; Methylphenidate; Middle Aged; Positron-Emission Tomography; Presynaptic Terminals; Substantia Nigra; Tetrabenazine; Tourette Syndrome; Vesicular Monoamine Transport Proteins; Young Adult | 2009 |
Dopamine transporter PET in normal aging: dopamine transporter decline and its possible role in preservation of motor function.
Topics: Adult; Aged; Aging; Brain; Carbon Radioisotopes; Caudate Nucleus; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Methylphenidate; Middle Aged; Motor Activity; Neuropsychological Tests; Positron-Emission Tomography; Putamen; Tetrabenazine | 2010 |
The effect of chronic methylphenidate administration on presynaptic dopaminergic parameters in a rat model for ADHD.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Binding Sites; Brain; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Methylphenidate; Piperazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Dopamine; Synaptosomes; Tetrabenazine; Time Factors; Vesicular Monoamine Transport Proteins | 2010 |
Age-specific progression of nigrostriatal dysfunction in Parkinson's disease.
Topics: Adult; Aged; Aging; Carbon Isotopes; Corpus Striatum; Disease Progression; Female; Fluorodeoxyglucose F18; Humans; Longitudinal Studies; Male; Methylphenidate; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Protein Binding; Substantia Nigra; Tetrabenazine; Tritium; Young Adult | 2011 |
DJ-1 and αSYN in LRRK2 CSF do not correlate with striatal dopaminergic function.
Topics: alpha-Synuclein; Biomarkers; Carbon Isotopes; Corpus Striatum; Dopamine; Female; Fluorodeoxyglucose F18; Humans; Intracellular Signaling Peptides and Proteins; Japan; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Luria-Nebraska Neuropsychological Battery; Male; Methylphenidate; Norway; Oncogene Proteins; Parkinson Disease; Positron-Emission Tomography; Protein Deglycase DJ-1; Protein Serine-Threonine Kinases; Statistics as Topic; Tetrabenazine; United States | 2012 |