Page last updated: 2024-09-03

dihydrotetrabenazine and levodopa

dihydrotetrabenazine has been researched along with levodopa in 7 studies

Compound Research Comparison

Studies
(dihydrotetrabenazine)
Trials
(dihydrotetrabenazine)
Recent Studies (post-2010)
(dihydrotetrabenazine)
Studies
(levodopa)
Trials
(levodopa)
Recent Studies (post-2010) (levodopa)
23446017,7741,9004,946

Protein Interaction Comparison

ProteinTaxonomydihydrotetrabenazine (IC50)levodopa (IC50)
integrase, partialHuman immunodeficiency virus 10.5939
lens epithelium-derived growth factor p75Homo sapiens (human)0.5939
Epidermal growth factor receptorHomo sapiens (human)2.88
Tyrosine-protein kinase LckHomo sapiens (human)3.729
Tyrosine-protein kinase FynHomo sapiens (human)2.146
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)2.258

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Calne, DB; De La Fuente-Fernández, R; Furtado, S; Furukawa, Y; Guttman, M; Lee, CS; Ruth, TJ; Stoessl, AJ1
Kumar, A; Lee, CS; Mann, S; Ruth, TJ; Schulzer, M; Sossi, V; Stoessl, AJ1
Brooks, DJ; Frey, KA; Marek, KL; Oakes, D; Paty, D; Prentice, R; Shults, CW; Stoessl, AJ1
Adams, JR; Calne, DB; Farrer, M; Gasser, T; Lee, CS; Mak, E; Mckenzie, J; Ruth, TJ; Schulzer, M; Sossi, V; Stoessl, AJ; Strongosky, A; Uitti, RJ; van Netten, H; Wszolek, ZK1
de la Fuente-Fernández, R; McCormick, S; Ruth, TJ; Schulzer, M; Sossi, V; Stoessl, AJ1
Bohnen, NI; Dayalu, P; Kwak, Y; Miller, NS; Müller, ML; Seidler, RD1
Appel-Cresswell, S; Dickson, DW; Dinelle, K; Farrer, MJ; McCormick, SE; McKenzie, J; Rajput, A; Rajput, AH; Robinson, CA; Silva, V; Sossi, V; Stoessl, AJ; Thompson, C; Vilariño-Güell, C1

Reviews

1 review(s) available for dihydrotetrabenazine and levodopa

ArticleYear
Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease.
    Experimental neurology, 2003, Volume: 184 Suppl 1

    Topics: Animals; Basal Ganglia; Biomarkers; Cocaine; Diagnostic Imaging; Dihydroxyphenylalanine; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Humans; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Parkinson Disease; Radiopharmaceuticals; Technology Assessment, Biomedical; Tetrabenazine; Tomography, Emission-Computed, Single-Photon; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

2003

Other Studies

6 other study(ies) available for dihydrotetrabenazine and levodopa

ArticleYear
VMAT2 binding is elevated in dopa-responsive dystonia: visualizing empty vesicles by PET.
    Synapse (New York, N.Y.), 2003, Volume: 49, Issue:1

    Topics: Adolescent; Adult; Carbon Radioisotopes; Corpus Striatum; Cytoplasmic Vesicles; Dopamine; Dopamine Agents; Dystonic Disorders; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Middle Aged; Neuropeptides; Parkinson Disease; Raclopride; Tetrabenazine; Tomography, Emission-Computed; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

2003
[11C]DTBZ-PET correlates of levodopa responses in asymmetric Parkinson's disease.
    Brain : a journal of neurology, 2003, Volume: 126, Issue:Pt 12

    Topics: Aged; Antiparkinson Agents; Dopamine; Fingers; Humans; Image Processing, Computer-Assisted; Levodopa; Middle Aged; Movement; Parkinson Disease; Reaction Time; Synaptic Vesicles; Tetrabenazine; Tomography, Emission-Computed

2003
PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation.
    Brain : a journal of neurology, 2005, Volume: 128, Issue:Pt 12

    Topics: Adult; Age Factors; Aged; Brain; Carbon Radioisotopes; Carboxy-Lyases; Case-Control Studies; Dopamine Plasma Membrane Transport Proteins; Fluorine Radioisotopes; Humans; Image Processing, Computer-Assisted; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Levodopa; Methylphenidate; Middle Aged; Mutation; Parkinson Disease; Phenotype; Positron-Emission Tomography; Protein Serine-Threonine Kinases; Radiopharmaceuticals; Receptors, Dopamine D2; Regression Analysis; Tetrabenazine

2005
Visualizing vesicular dopamine dynamics in Parkinson's disease.
    Synapse (New York, N.Y.), 2009, Volume: 63, Issue:8

    Topics: Antiparkinson Agents; Brain Mapping; Carbon Radioisotopes; Dopamine; Female; Humans; Levodopa; Male; Middle Aged; Nonlinear Dynamics; Parkinson Disease; Positron-Emission Tomography; Tetrabenazine

2009
The pattern of striatal dopaminergic denervation explains sensorimotor synchronization accuracy in Parkinson's disease.
    Behavioural brain research, 2013, Nov-15, Volume: 257

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Carbon Isotopes; Cluster Analysis; Corpus Striatum; Dopamine; Female; Humans; Levodopa; Male; Middle Aged; Motor Activity; Parkinson Disease; Positron-Emission Tomography; Psychomotor Performance; Tetrabenazine; Time Factors; Time Perception

2013
Clinical, positron emission tomography, and pathological studies of DNAJC13 p.N855S Parkinsonism.
    Movement disorders : official journal of the Movement Disorder Society, 2014, Volume: 29, Issue:13

    Topics: Aged; Aged, 80 and over; Brain; Carbon Isotopes; Dopamine Agents; Family Health; Fluorodeoxyglucose F18; Humans; Levodopa; Middle Aged; Molecular Chaperones; Mutation; Parkinsonian Disorders; Positron-Emission Tomography; Tetrabenazine

2014