Page last updated: 2024-09-03

dihydrotetrabenazine and ketanserin

dihydrotetrabenazine has been researched along with ketanserin in 3 studies

Compound Research Comparison

Studies
(dihydrotetrabenazine)
Trials
(dihydrotetrabenazine)
Recent Studies (post-2010)
(dihydrotetrabenazine)
Studies
(ketanserin)
Trials
(ketanserin)
Recent Studies (post-2010) (ketanserin)
2344603,094335283

Protein Interaction Comparison

ProteinTaxonomydihydrotetrabenazine (IC50)ketanserin (IC50)
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0016
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0021
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.015
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.015
5-hydroxytryptamine receptor 1DHomo sapiens (human)0.265
5-hydroxytryptamine receptor 1BHomo sapiens (human)6.5
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0184
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.0027
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0016
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.29
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.015
D(2) dopamine receptorRattus norvegicus (Norway rat)1.8
Synaptic vesicular amine transporterHomo sapiens (human)0.18
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.001

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eshleman, AJ; Gonzalez, M; Janowsky, A; Johnson, RA; Kryatova, O; Meltzer, PC; Nelson, J; Provencher, BA; Shi, X; Tian, J1
Bertocci, B; Cesura, AM; Da Prada, M1
Darchen, F; Masuo, Y; Rostene, W; Scherman, D; Vial, M1

Other Studies

3 other study(ies) available for dihydrotetrabenazine and ketanserin

ArticleYear
Synthesis and Discovery of Arylpiperidinylquinazolines: New Inhibitors of the Vesicular Monoamine Transporter.
    Journal of medicinal chemistry, 2018, 10-25, Volume: 61, Issue:20

    Topics: Animals; Chemistry Techniques, Synthetic; Drug Design; HEK293 Cells; Humans; Ligands; Mice; Quinazolines; Vesicular Monoamine Transport Proteins

2018
Binding of [3H]dihydrotetrabenazine and [125I]azidoiodoketanserin photoaffinity labeling of the monoamine transporter of platelet 5-HT organelles.
    European journal of pharmacology, 1990, Sep-04, Volume: 186, Issue:1

    Topics: Affinity Labels; Animals; Azides; Biogenic Monoamines; Blood Platelets; Blood Proteins; Cell Membrane; Guinea Pigs; Humans; In Vitro Techniques; Iodine Radioisotopes; Ketanserin; Paroxetine; Photochemistry; Piperidines; Rabbits; Rats; Receptors, Serotonin; Subcellular Fractions; Tetrabenazine

1990
Quantitative autoradiography of the rat brain vesicular monoamine transporter using the binding of [3H]dihydrotetrabenazine and 7-amino-8-[125I]iodoketanserin.
    Neuroscience, 1989, Volume: 33, Issue:2

    Topics: Animals; Biogenic Monoamines; Brain; In Vitro Techniques; Ketanserin; Male; Rats; Rats, Inbred Strains; Tetrabenazine

1989