dihydrosanguinarine has been researched along with sanguinarine in 10 studies
| Studies (dihydrosanguinarine) | Trials (dihydrosanguinarine) | Recent Studies (post-2010) (dihydrosanguinarine) | Studies (sanguinarine) | Trials (sanguinarine) | Recent Studies (post-2010) (sanguinarine) |
|---|---|---|---|---|---|
| 28 | 0 | 17 | 675 | 37 | 290 |
| Protein | Taxonomy | dihydrosanguinarine (IC50) | sanguinarine (IC50) |
|---|---|---|---|
| Cholinesterase | Homo sapiens (human) | 7.08 | |
| Nuclear factor NF-kappa-B p105 subunit | Homo sapiens (human) | 2 | |
| Acetylcholinesterase | Homo sapiens (human) | 1.22 | |
| Nuclear factor NF-kappa-B p100 subunit | Homo sapiens (human) | 2 | |
| Transcription factor p65 | Homo sapiens (human) | 2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klejdus, B; Kosina, P; Kubán, V; Psotová, J; Simánek, V; Ulrichová, J; Vecera, R; Vicar, J | 1 |
| Anzenbacher, P; Dvorák, Z; Klejdus, B; Kosina, P; Kubán, V; Orolin, J; Simánek, V; Smrcek, S; Stiborová, M; Ulrichová, J; Vecera, R; Vicar, J | 1 |
| SARKAR, SM | 1 |
| Dolezel, P; Ulrichová, J; Vicar, J; Vrba, J | 1 |
| Janovská, M; Kubala, M; Simánek, V; Ulrichová, J | 2 |
| Hao, X; Meng, F; Wang, G; Xiao, H; Xu, G; Zhang, J; Zuo, G | 1 |
| Li, YJ; Liu, ZY; Sun, ZL; Zhang, DS | 1 |
| Donohoe, TJ; Simpson, I; Tatton, MR | 1 |
| Gao, L; Merz, KH; Schmitz, HJ; Schrenk, D | 1 |
10 other study(ies) available for dihydrosanguinarine and sanguinarine
| Article | Year |
|---|---|
A liquid chromatographic-mass spectrometric evidence of dihydrosanguinarine as a first metabolite of sanguinarine transformation in rat.
Topics: Alkaloids; Animals; Benzophenanthridines; Biotransformation; Chromatography, High Pressure Liquid; Isoquinolines; Male; Phenanthridines; Rats; Rats, Wistar; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2006 |
Disposition of sanguinarine in the rat.
Topics: Acridines; Administration, Oral; Alkaloids; Animals; Anti-Infective Agents; Benzophenanthridines; Isoquinolines; Male; Mass Spectrometry; Rats; Rats, Wistar; Time Factors; Tissue Distribution; Tritium | 2007 |
Isolation from argemone oil of dihydrosanguinarine and sanguinarine; toxicity of sanguinarine.
Topics: Benzophenanthridines; Humans; Isoquinolines; Plant Oils | 1948 |
Cytotoxic activity of sanguinarine and dihydrosanguinarine in human promyelocytic leukemia HL-60 cells.
Topics: Apoptosis; Benzophenanthridines; Caspases; Cell Cycle; Cell Survival; HL-60 Cells; Humans; Isoquinolines; Membrane Potential, Mitochondrial | 2009 |
Fluorescence of sanguinarine: fundamental characteristics and analysis of interconversion between various forms.
Topics: Anti-Infective Agents; Benzophenanthridines; Cardiotonic Agents; Cells, Cultured; Fluorescence; Hepatocytes; Humans; Isoquinolines; Spectrometry, Fluorescence | 2009 |
Antifungal activity of the benzo[c]phenanthridine alkaloids from Chelidonium majus Linn against resistant clinical yeast isolates.
Topics: Alkaloids; Antifungal Agents; Benzophenanthridines; Candida; Chelidonium; Drug Evaluation, Preclinical; Drug Resistance; Heterocyclic Compounds, 4 or More Rings; Humans; Isoquinolines; Microbial Sensitivity Tests; Molecular Structure; Plant Extracts; Plants, Medicinal; Reference Standards | 2009 |
Interaction of sanguinarine and its dihydroderivative with the Na+/K+-ATPase. Complex view on the old problem.
Topics: Benzophenanthridines; Enzyme Inhibitors; Isoquinolines; Sodium-Potassium-Exchanging ATPase | 2010 |
NQO1 involves in the imine bond reduction of sanguinarine and recombinant adeno-associated virus mediated NQO1 overexpression decreases sanguinarine-induced cytotoxicity in rat BRL cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Benzophenanthridines; Biotransformation; Cell Proliferation; Cell Survival; Cytochrome P-450 CYP1A1; Dependovirus; Dose-Response Relationship, Drug; Genetic Vectors; HEK293 Cells; Humans; Isoquinolines; Liver; NAD(P)H Dehydrogenase (Quinone); NADP; Oxidation-Reduction; Proto-Oncogene Proteins c-bcl-2; Rats; Time Factors; Transfection | 2014 |
New methods for the synthesis of naphthyl amines; application to the synthesis of dihydrosanguinarine, sanguinarine, oxysanguinarine and (±)-maclekarpines B and C.
Topics: Amines; Benzodioxoles; Benzophenanthridines; Biological Products; Isoquinolines; Phenanthridines | 2014 |
Characterization of the cytotoxicity of selected Chelidonium alkaloids in rat hepatocytes.
Topics: Alkaloids; Animals; Benzophenanthridines; Berberine; Cells, Cultured; Chelidonium; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Glutathione; Hepatocytes; Isoquinolines; Male; Molecular Structure; Primary Cell Culture; Rats, Wistar; Structure-Activity Relationship | 2019 |