Page last updated: 2024-09-03

dihydrosanguinarine and berberine

dihydrosanguinarine has been researched along with berberine in 2 studies

*Berberine: An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal. [MeSH]

*Berberine: An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal. [MeSH]

Compound Research Comparison

Studies
(dihydrosanguinarine)
Trials
(dihydrosanguinarine)
Recent Studies (post-2010)
(dihydrosanguinarine)
Studies
(berberine)
Trials
(berberine)
Recent Studies (post-2010) (berberine)
280174,1061022,791

Protein Interaction Comparison

ProteinTaxonomydihydrosanguinarine (IC50)berberine (IC50)
AcetylcholinesteraseElectrophorus electricus (electric eel)0.7827
Lysine-specific histone demethylase 1AHomo sapiens (human)6.97
CholinesteraseHomo sapiens (human)1.09
AcetylcholinesteraseHomo sapiens (human)0.4
Aldo-keto reductase family 1 member C3Homo sapiens (human)4.99
Aldo-keto reductase family 1 member C2 Homo sapiens (human)6.71
CholinesteraseEquus caballus (horse)9.4
Cytochrome P450 1B1Homo sapiens (human)0.9747

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheng, P; Kang, W; Liu, S; Liu, W; Qing, Z; Xie, H; Zeng, J; Zhou, J1
Gao, L; Merz, KH; Schmitz, HJ; Schrenk, D1

Other Studies

2 other study(ies) available for dihydrosanguinarine and berberine

ArticleYear
Synthesis of 5-methyl phenanthridium derivatives: a new class of human DOPA decarboxylase inhibitors.
    Bioorganic & medicinal chemistry letters, 2014, Jun-15, Volume: 24, Issue:12

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Enzyme Activation; Humans; Inhibitory Concentration 50; Molecular Structure; Phenanthridines; Rats

2014
Characterization of the cytotoxicity of selected Chelidonium alkaloids in rat hepatocytes.
    Toxicology letters, 2019, Sep-01, Volume: 311

    Topics: Alkaloids; Animals; Benzophenanthridines; Berberine; Cells, Cultured; Chelidonium; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Glutathione; Hepatocytes; Isoquinolines; Male; Molecular Structure; Primary Cell Culture; Rats, Wistar; Structure-Activity Relationship

2019