Page last updated: 2024-09-02

dihydrokainate and riluzole

dihydrokainate has been researched along with riluzole in 3 studies

Compound Research Comparison

Studies
(dihydrokainate)
Trials
(dihydrokainate)
Recent Studies (post-2010)
(dihydrokainate)
Studies
(riluzole)
Trials
(riluzole)
Recent Studies (post-2010) (riluzole)
1800461,244153572

Protein Interaction Comparison

ProteinTaxonomydihydrokainate (IC50)riluzole (IC50)
Sodium channel protein type 2 subunit alphaRattus norvegicus (Norway rat)4.73
Cytochrome P450 1A2Homo sapiens (human)10
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.733
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.733

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Fumagalli, E; Funicello, M; Gobbi, M; Mennini, T; Rauen, T1
Eisenach, JC; Hayashida, K; Hobo, S1

Other Studies

3 other study(ies) available for dihydrokainate and riluzole

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1.
    European journal of pharmacology, 2008, Jan-14, Volume: 578, Issue:2-3

    Topics: Amino Acid Transport System X-AG; Animals; Cell Line; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamic Acid; Humans; Kainic Acid; Kinetics; Male; Neuroprotective Agents; Rats; Riluzole; Serine; Synaptosomes; Transfection

2008
Up-regulation of spinal glutamate transporters contributes to anti-hypersensitive effects of valproate in rats after peripheral nerve injury.
    Neuroscience letters, 2011, Sep-08, Volume: 502, Issue:1

    Topics: Analgesics; Animals; Disease Models, Animal; Drug Therapy, Combination; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Hyperalgesia; Kainic Acid; Pain Threshold; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Riluzole; Spinal Cord; Up-Regulation; Valproic Acid

2011