Page last updated: 2024-09-02

dihydrokainate and morphine

dihydrokainate has been researched along with morphine in 3 studies

Compound Research Comparison

Studies
(dihydrokainate)
Trials
(dihydrokainate)
Recent Studies (post-2010)
(dihydrokainate)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
18004644,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomydihydrokainate (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Terman, GW; Thomson, LM; Zeng, J1
Baron, DA; Patel, D; Patel, H; Rawls, SM; Sacavage, S; Zielinski, M1
Li, J; Lu, XQ; Su, RB; Wu, N; Yan, HT; Zheng, JQ1

Other Studies

3 other study(ies) available for dihydrokainate and morphine

ArticleYear
Differential effect of glutamate transporter inhibition on EPSCs in the morphine naïve and morphine tolerant neonatal spinal cord slice.
    Neuroscience letters, 2006, Oct-16, Volume: 407, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Analysis of Variance; Animals; Aspartic Acid; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Kainic Acid; Morphine; Narcotics; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord

2006
Beta-lactam antibiotic reduces morphine analgesic tolerance in rats through GLT-1 transporter activation.
    Drug and alcohol dependence, 2010, Mar-01, Volume: 107, Issue:2-3

    Topics: Analgesics, Opioid; Animals; Anti-Bacterial Agents; Ceftriaxone; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Transporter 2; Hot Temperature; Injections, Intraperitoneal; Injections, Subcutaneous; Kainic Acid; Male; Morphine; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time

2010
Aquaporin-4 deficiency attenuates opioid dependence through suppressing glutamate transporter-1 down-regulation and maintaining glutamate homeostasis.
    CNS neuroscience & therapeutics, 2013, Volume: 19, Issue:1

    Topics: Animals; Aquaporin 4; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Homeostasis; Kainic Acid; Mice; Mice, Knockout; Microdialysis; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Tritium

2013