dihydrokainate has been researched along with aspartic acid in 57 studies
| Studies (dihydrokainate) | Trials (dihydrokainate) | Recent Studies (post-2010) (dihydrokainate) | Studies (aspartic acid) | Trials (aspartic acid) | Recent Studies (post-2010) (aspartic acid) |
|---|---|---|---|---|---|
| 180 | 0 | 46 | 23,005 | 417 | 4,018 |
| Protein | Taxonomy | dihydrokainate (IC50) | aspartic acid (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 1.638 | |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | 90.1265 | |
| Excitatory amino acid transporter 2 | Homo sapiens (human) | 11 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 1.638 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 1.638 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 1.638 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 1.638 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 1.638 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 1.638 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (8.77) | 18.7374 |
| 1990's | 21 (36.84) | 18.2507 |
| 2000's | 24 (42.11) | 29.6817 |
| 2010's | 7 (12.28) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Attwell, D; Barbour, B; Brew, H | 1 |
| Hestrin, S; Nicoll, RA; Sah, P | 1 |
| Higashima, M; Sawada, S; Yamamoto, C | 1 |
| Brodin, L; Grillner, S; Ohta, Y; Tossman, U; Ungerstedt, U | 1 |
| Besharse, JC; Spratt, G | 1 |
| Hagberg, H; Hamberger, A; Jacobson, I; Lazarewicz, JW; Lehmann, A | 1 |
| Jhamandas, K; Notman, H; Whitney, R | 1 |
| Larsson, HP; Lecar, H; Picaud, S; Wellis, DP; Werblin, F | 1 |
| Davies, JA; Dickie, BG | 1 |
| Curtis, JT; Sved, AF | 1 |
| Greenberg, DA; Koretz, B; Lustig, HS; von B Ahern, K; Wang, N | 1 |
| Andersson, K; Chen, Y; Espinoza, S; Godukhin, OV; Goiny, M; Herrera-Marschitz, M; Loidl, CF; Lubec, G; Meana, JJ; Nylander, I; Pettersson, E; Silveira, R; Terenius, L; Ungerstedt, U; You, ZB | 1 |
| Massieu, L; Tapia, R; Velasco, I | 1 |
| Lewin, L; Mattsson, MO; Sellström, A | 1 |
| Allan, RD; Balcar, VJ; Bested, A; Blume, GL; Bohart, L; Cooper, B; Dias, LS; Killinger, S | 1 |
| Bouazzaoui, M; Gombos, G; Kannengieser, C; Procksch, O | 1 |
| Wu, SM; Yang, JH | 1 |
| Massieu, L; Tapia, R | 1 |
| Gaal, L; Marc, R; Picaud, SA; Roska, B; Werblin, FS; Wu, SM | 1 |
| Crosson, CE; Ganel, R | 1 |
| Grunewald, M; Kanner, BI; Kavanaugh, MP; Zarbiv, R | 1 |
| Davis, RE | 1 |
| Leza, JC; Lizasoain, I; Lorenzo, P; Moro, MA | 1 |
| Feustel, PJ; Keller, RW; Kimelberg, HK; Seki, Y; Tranmer, BI | 1 |
| Kanner, BI; Zhang, Y | 1 |
| Bridges, RJ; Chamberlin, AR; Koch, HP | 1 |
| Berger, SP; Fox, L; Ho, LB; Reid, MS | 1 |
| Araque, A; Doyle, RT; Haydon, PG; Li, N | 1 |
| Trussell, LO; Turecek, R | 1 |
| Isaac, JT; Kidd, FL | 2 |
| Diamond, JS; Jahr, CE | 1 |
| Bézine, MF; Gaillet, S; Malaval, F; Plachez, C; Récasens, M | 1 |
| Dawson, LA; Djali, S; Gonzales, C; Vinegra, MA; Zaleska, MM | 1 |
| Chatton, JY; Magistretti, PJ; Shimamoto, K | 1 |
| Anderson, CM; Bridges, RJ; Chamberlin, AR; Shimamoto, K; Swanson, RA; Yasuda-Kamatani, Y | 1 |
| Chen, Y; Swanson, RA | 1 |
| Fei, J; Guo, LH; Hu, JH; Jiang, J; Ma, YH; Yang, N; Zhang, JF | 1 |
| Feustel, PJ; Jin, Y; Kimelberg, HK | 1 |
| Grebenyuk, S; Kirichok, Y; Krishtal, O; Lozovaya, N; Melnik, S; Tsintsadze, T | 1 |
| Kettenmann, H; Kresse, W; Rose, C | 1 |
| Foster, AC; Naeve, GS; Poulsen, DJ; Selkirk, JV; Stiefel, TH; Stone, IM | 1 |
| Cechova, S; Zuo, Z | 1 |
| Terman, GW; Thomson, LM; Zeng, J | 1 |
| Bonanno, G; Fedele, E; Milanese, M; Raiteri, L; Raiteri, M; Zappettini, S | 1 |
| Campbell, SL; Hablitz, JJ | 1 |
| Bernardinelli, Y; Chatton, JY | 1 |
| Hille, B; Kim, MH; Koh, DS; Moriyama, Y; Muroyama, A; Uehara, S | 1 |
| DeSilva, TM; Goldhoff, PE; Kabakov, AY; Rosenberg, PA; Volpe, JJ | 1 |
| Kardos, J; Lasztóczi, B; Nyitrai, G | 1 |
| Bertsche, A; Bruehl, C; Draguhn, A; Pietz, J | 1 |
| Guan, X; Lu, W; Petralia, RS; Rothstein, JD; Tao, YX; Yaster, M | 1 |
| Barton, SJ; Bunner, KD; Dorner, JL; Gaither, TW; Klein, EL; Miller, BR; Rebec, GV | 1 |
| Jiang, E; Weng, HR; Yan, X | 1 |
| Colbert, CM; Eskin, A; Pita-Almenar, JD; Zou, S | 1 |
| Fischer, KD; Houston, AC; Rebec, GV | 1 |
57 other study(ies) available for dihydrokainate and aspartic acid
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Electrogenic uptake of glutamate and aspartate into glial cells isolated from the salamander (Ambystoma) retina.
Topics: Ambystoma; Animals; Aspartic Acid; Calcium; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Magnesium; Membrane Potentials; Neuroglia; Potassium; Retina; Sodium | 1991 |
Mechanisms generating the time course of dual component excitatory synaptic currents recorded in hippocampal slices.
Topics: Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Ketamine; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Temperature; Time Factors | 1990 |
Inhibitors of high-affinity uptake augment depolarizations of hippocampal neurons induced by glutamate, kainate and related compounds.
Topics: Animals; Aspartic Acid; Drug Synergism; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Homocysteine; In Vitro Techniques; Kainic Acid; Oxadiazoles; Quisqualic Acid; Synaptic Transmission | 1985 |
The effect of an uptake inhibitor (dihydrokainate) on endogenous excitatory amino acids in the lamprey spinal cord as revealed by microdialysis.
Topics: Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Kainic Acid; Lampreys; Neurotransmitter Agents; Reference Values; Spinal Cord | 1988 |
Excitatory amino acids and rod photoreceptor disc shedding: analysis using specific agonists.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; In Vitro Techniques; Kainic Acid; Light; N-Methylaspartate; Oxadiazoles; Phagosomes; Photoreceptor Cells; Pigment Epithelium of Eye; Quisqualic Acid; Rana pipiens; Xenopus laevis | 1988 |
Alterations in extracellular amino acids and Ca2+ following excitotoxin administration and during status epilepticus.
Topics: Amino Acids; Animals; Aspartic Acid; Bicuculline; Calcium; Epilepsy; Ethanolamines; Extracellular Space; Glutamates; Hippocampus; Kainic Acid; N-Methylaspartate; Rabbits; Synaptic Membranes; Synaptosomes; Taurine; Tetrodotoxin | 1986 |
Kainic acid evoked release of D-[3H]aspartate from rat striatum in vitro: characterization and pharmacological modulation.
Topics: Animals; Aspartic Acid; Bromocriptine; Calcium; Corpus Striatum; Female; In Vitro Techniques; Kainic Acid; Potassium; Pyrrolidines; Rats; Rats, Inbred Strains; Sodium; Tritium | 1984 |
Cone photoreceptors respond to their own glutamate release in the tiger salamander.
Topics: Ambystoma; Animals; Aspartic Acid; Calcium; Chloride Channels; Exocytosis; Fluorescent Dyes; Fura-2; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Ion Channel Gating; Kainic Acid; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Retinal Cone Photoreceptor Cells; Synapses; Synaptic Transmission; Time Factors | 1995 |
Modulation of calcium-dependent and -independent components of veratridine-evoked release of glutamate from rat cerebellum.
Topics: Amiloride; Animals; Apamin; Aspartic Acid; Calcium; Calcium Channel Blockers; Cerebellum; Cobalt; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Kinetics; omega-Conotoxins; Peptides; Perfusion; Rats; Rats, Wistar; Ruthenium Red; Tetrodotoxin; Verapamil; Veratridine | 1993 |
Amino acid neurotransmitters in nucleus tractus solitarius: an in vivo microdialysis study.
Topics: Afferent Pathways; Amino Acids; Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Electric Stimulation; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Male; Membrane Potentials; Microdialysis; Nerve Endings; Neurotransmitter Agents; Nodose Ganglion; Potassium; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Time Factors; Vagus Nerve | 1993 |
Pre- and post-synaptic modulators of excitatory neurotransmission: comparative effects on hypoxia/hypoglycemia in cortical cultures.
Topics: Animals; Aspartic Acid; Benzopyrans; Calcium Channel Blockers; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Cromakalim; Diazoxide; Embryo, Mammalian; Glutamates; Hypoglycemia; Kainic Acid; Kinetics; L-Lactate Dehydrogenase; Neurons; Potassium Channels; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Time Factors | 1994 |
On the origin of extracellular glutamate levels monitored in the basal ganglia of the rat by in vivo microdialysis.
Topics: Amino Acids; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Aspartic Acid; Basal Ganglia; Calcium; Cerebral Cortex; Dicarboxylic Acids; Glutamic Acid; Halothane; Kainic Acid; Male; Membrane Potentials; Microdialysis; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Potassium; Presynaptic Terminals; Pyrrolidines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Spider Venoms; Substantia Nigra; Tetrodotoxin; Urethane | 1996 |
Inhibition of glutamate uptake induces progressive accumulation of extracellular glutamate and neuronal damage in rat cortical cultures.
Topics: Animals; Anti-Bacterial Agents; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Kainic Acid; L-Lactate Dehydrogenase; Nerve Degeneration; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1996 |
Differences in the release of L-glutamate and D-aspartate from primary neuronal chick cultures.
Topics: Animals; Aspartic Acid; Biological Transport; Cells, Cultured; Chick Embryo; Drug Evaluation, Preclinical; Exocytosis; Glutamates; Glutamic Acid; Kainic Acid; Neurons | 1996 |
Autoradiographic studies indicate regional variations in the characteristics of L-glutamate transporters in the rat brain.
Topics: Amino Acid Transport System X-AG; Animals; Anti-Bacterial Agents; Aspartic Acid; ATP-Binding Cassette Transporters; Autoradiography; Binding Sites; Biological Transport; Brain Chemistry; Cerebral Cortex; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Female; Hippocampus; Kainic Acid; Male; Neostriatum; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Tritium | 1996 |
Kainic acid, AMPA, and dihydrokainic acid effect on uptake and efflux of D-[3H] aspartic acid in cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Kinetics; Quinoxalines; Rats; Rats, Wistar; Tetrodotoxin; Tritium | 1996 |
Characterization of glutamate transporter function in the tiger salamander retina.
Topics: Ambystoma; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Autoradiography; Biological Transport; Glutamates; In Vitro Techniques; Kainic Acid; Membrane Potentials; Microscopy, Electron; Photic Stimulation; Retina; Time Factors | 1997 |
Glutamate uptake impairment and neuronal damage in young and aged rats in vivo.
Topics: Aging; Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Dicarboxylic Acids; Glutamic Acid; Hippocampus; Kainic Acid; Kinetics; Male; Microdialysis; Nerve Degeneration; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar | 1997 |
Postsynaptic response kinetics are controlled by a glutamate transporter at cone photoreceptors.
Topics: Ambystoma; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Calcium; Darkness; Glutamic Acid; Kainic Acid; Kinetics; Light; Magnesium; Membrane Potentials; Patch-Clamp Techniques; Retina; Retinal Cone Photoreceptor Cells; Synapses; Synaptic Transmission | 1998 |
Modulation of human glutamate transporter activity by phorbol ester.
Topics: Amino Acid Transport System X-AG; Anti-Bacterial Agents; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Carcinogens; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamates; Glutamic Acid; Humans; Kainic Acid; Kinetics; Phorbol Esters; Protein Kinase C; Retinoblastoma; Staurosporine; Tumor Cells, Cultured | 1998 |
Cysteine scanning of the surroundings of an alkali-ion binding site of the glutamate transporter GLT-1 reveals a conformationally sensitive residue.
Topics: Amino Acid Transport System X-AG; Amino Acids; Aspartic Acid; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport; Conserved Sequence; Cysteine; Ethylmaleimide; HeLa Cells; Humans; Kainic Acid; Mesylates; Mutagenesis, Site-Directed; Potassium; Protein Conformation; Sodium; Sulfhydryl Reagents | 1998 |
Action of excitatory amino acids on hypodermis and the motornervous system of Ascaris suum: pharmacological evidence for a glutamate transporter.
Topics: Amino Acid Transport System X-AG; Animals; Ascaris suum; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport, Active; Calcium; Dose-Response Relationship, Drug; Electric Conductivity; Epithelium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Membrane Potentials; Microelectrodes; Motor Neurons; Quinoxalines; Sodium | 1998 |
Peroxynitrite causes aspartate release from dissociated rat cerebellar granule neurones.
Topics: Animals; Aspartic Acid; Brain Ischemia; Calcium; Cerebellar Cortex; Dithiothreitol; Egtazic Acid; Glutamic Acid; Ion Transport; Kainic Acid; Membrane Proteins; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide; Oxidants; Oxidation-Reduction; Rats; Rats, Wistar; Sodium; Sulfhydryl Compounds; Superoxides; Tetrodotoxin | 1998 |
Inhibition of ischemia-induced glutamate release in rat striatum by dihydrokinate and an anion channel blocker.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Blood Flow Velocity; Brain Ischemia; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Corpus Striatum; Drug Therapy, Combination; Glutamic Acid; Ion Pumps; Kainic Acid; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Stilbenes | 1999 |
Two serine residues of the glutamate transporter GLT-1 are crucial for coupling the fluxes of sodium and the neurotransmitter.
Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Aspartic Acid; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport; Glutamic Acid; Glycine; HeLa Cells; Humans; Kainic Acid; Kinetics; Mutagenesis, Site-Directed; Neurotransmitter Agents; Recombinant Proteins; Serine; Sodium | 1999 |
Nontransportable inhibitors attenuate reversal of glutamate uptake in synaptosomes following a metabolic insult.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Brain; Dicarboxylic Acids; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Pyrrolidines; Rats; Synaptosomes; Tritium | 1999 |
Nicotine stimulation of extracellular glutamate levels in the nucleus accumbens: neuropharmacological characterization.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Denervation; Dicarboxylic Acids; Dopamine; Extracellular Space; Glutamic Acid; Haloperidol; Kainic Acid; Kinetics; Male; Mecamylamine; Microdialysis; Neurotransmitter Uptake Inhibitors; Nicotine; Nucleus Accumbens; Oxidopamine; Pyrrolidines; Rats; Rats, Sprague-Dawley | 2000 |
SNARE protein-dependent glutamate release from astrocytes.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Anti-Bacterial Agents; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Botulinum Toxins; Botulinum Toxins, Type A; Calcium; Cells, Cultured; Coculture Techniques; Dicarboxylic Acids; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Kainic Acid; Macrolides; Membrane Potentials; Membrane Proteins; Nerve Tissue Proteins; Neurons; Proton-Translocating ATPases; Pyrrolidines; Rats; SNARE Proteins; Vesicular Transport Proteins | 2000 |
Control of synaptic depression by glutamate transporters.
Topics: Action Potentials; Alanine Transaminase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Anti-Bacterial Agents; Antihypertensive Agents; Aspartic Acid; ATP-Binding Cassette Transporters; Benzothiadiazines; Chick Embryo; Cochlear Nucleus; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Receptors, AMPA; Synaptic Transmission | 2000 |
Glutamate transport blockade has a differential effect on AMPA and NMDA receptor-mediated synaptic transmission in the developing barrel cortex.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Benzothiadiazines; Biological Transport; Dicarboxylic Acids; Diuretics; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Neurotransmitter Uptake Inhibitors; Picrotoxin; Pyrrolidines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Chloride Symporter Inhibitors; Somatosensory Cortex; Synaptic Transmission; Thalamus | 2000 |
Synaptically released glutamate does not overwhelm transporters on hippocampal astrocytes during high-frequency stimulation.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Biological Transport; Cells, Cultured; Drug Synergism; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Synapses; Synaptic Transmission; Theophylline | 2000 |
Transient increase in the high affinity [3H]-L-glutamate uptake activity during in vitro development of hippocampal neurons in culture.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Carrier Proteins; Cell Differentiation; Cells, Cultured; Culture Media, Serum-Free; Dicarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hippocampus; Kainic Acid; Neuroglia; Neurons; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Symporters; Time Factors; Tritium | 2001 |
Characterization of transient focal ischemia-induced increases in extracellular glutamate and aspartate in spontaneously hypertensive rats.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Brain; Brain Ischemia; Extracellular Space; Glutamic Acid; Infarction, Middle Cerebral Artery; Kainic Acid; Male; Rats; Rats, Inbred SHR; Reperfusion Injury; Tetrodotoxin; Time Factors | 2000 |
Effects of glial glutamate transporter inhibitors on intracellular Na+ in mouse astrocytes.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Benzofurans; Binding, Competitive; Cells, Cultured; Dicarboxylic Acids; Dose-Response Relationship, Drug; Ethers, Cyclic; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; Intracellular Fluid; Kainic Acid; Mice; Neurotransmitter Uptake Inhibitors; Protein Isoforms; Pyrrolidines; Sodium; Stereoisomerism | 2001 |
Kinetics and activation of postsynaptic kainate receptors at thalamocortical synapses: role of glutamate clearance.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Central Nervous System Stimulants; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Kainic Acid; Kinetics; Organ Culture Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, Kainic Acid; Synapses; Synaptic Transmission; Temperature; Thalamus | 2001 |
Differing effects of substrate and non-substrate transport inhibitors on glutamate uptake reversal.
Topics: Adenosine Triphosphate; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Biological Transport; Carrier Proteins; Cells, Cultured; Dicarboxylic Acids; Glutamic Acid; Kainic Acid; Mice; Nerve Tissue Proteins; Neurons; Prosencephalon; Pyrrolidines; Substrate Specificity | 2001 |
The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Binding, Competitive; Biological Transport; Cells, Cultured; Cerebral Cortex; Cysteine; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutathione; Kainic Acid; Mice; Neurons; Sodium; Symporters | 2003 |
Identification of glutamate transporters and receptors in mouse testis.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Brain; Cells, Cultured; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; GluK2 Kainate Receptor; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Symporters; Synaptosomes; Testis | 2004 |
Volume-regulated anion channels are the predominant contributors to release of excitatory amino acids in the ischemic cortical penumbra.
Topics: Amino Acid Transport System X-AG; Animals; Anion Transport Proteins; Aspartic Acid; Astrocytes; Brain Ischemia; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; Infarction, Middle Cerebral Artery; Kainic Acid; Microdialysis; Neurons; Rats; Receptors, Glutamate; Tamoxifen; Taurine | 2004 |
Protective cap over CA1 synapses: extrasynaptic glutamate does not reach the postsynaptic density.
Topics: 4-Aminopyridine; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Dizocilpine Maleate; Drug Interactions; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Models, Neurological; N-Methylaspartate; Neural Inhibition; Neurons; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Synapses | 2004 |
Acute insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes, an effect of pH.
Topics: Adenosine Triphosphate; Amino Acid Transport System X-AG; Ammonia; Animals; Aspartic Acid; Astrocytes; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Egtazic Acid; Endoplasmic Reticulum; Fluoresceins; Glutamic Acid; Hydrogen-Ion Concentration; Kainic Acid; Methylamines; Mice; Microscopy, Fluorescence; Spectrometry, Fluorescence; Thapsigargin; Ultraviolet Rays | 2005 |
Over-expression of the human EAAT2 glutamate transporter within neurons of mouse organotypic hippocampal slice cultures leads to increased vulnerability of CA1 pyramidal cells.
Topics: Amino Acid Transport System X-AG; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Blotting, Western; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Transporter 2; Gene Expression; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Humans; Kainic Acid; Mice; Neuroglia; Organ Culture Techniques; Phosphopyruvate Hydratase; Pyramidal Cells; Symporters; Time Factors; Transduction, Genetic; Tritium | 2005 |
Inhibition of glutamate transporters increases the minimum alveolar concentration for isoflurane in rats.
Topics: Amino Acid Transport System X-AG; Anesthetics, Inhalation; Animals; Aspartic Acid; Blood Pressure; Injections, Spinal; Isoflurane; Kainic Acid; Male; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Spinal Cord | 2006 |
Differential effect of glutamate transporter inhibition on EPSCs in the morphine naïve and morphine tolerant neonatal spinal cord slice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Analysis of Variance; Animals; Aspartic Acid; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Kainic Acid; Morphine; Narcotics; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord | 2006 |
Mechanisms of glutamate release elicited in rat cerebrocortical nerve endings by 'pathologically' elevated extraterminal K+ concentrations.
Topics: Animals; Aspartic Acid; Calcium Channels; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 2; Exocytosis; Extracellular Fluid; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hyperkalemia; Kainic Acid; Macrolides; Male; Potassium; Presynaptic Terminals; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Synaptosomes | 2007 |
Decreased glutamate transport enhances excitability in a rat model of cortical dysplasia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; Malformations of Cortical Development; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 2008 |
Differential effects of glutamate transporter inhibitors on the global electrophysiological response of astrocytes to neuronal stimulation.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Brain; Kainic Acid; Neurons; Patch-Clamp Techniques; Potassium; Rats; Rats, Sprague-Dawley | 2008 |
Glutamate transporter-mediated glutamate secretion in the mammalian pineal gland.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cesium; Chlorides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exocytosis; Glutamic Acid; In Vitro Techniques; Kainic Acid; Macrolides; Magnesium; Male; Melatonin; Membrane Potentials; Pineal Gland; Potassium Chloride; Rats; Rats, Sprague-Dawley | 2008 |
Regulation of glutamate transport in developing rat oligodendrocytes.
Topics: Animals; Animals, Newborn; Aspartic Acid; Benzodiazepines; Bicuculline; Brain; Cells, Cultured; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Female; Fibroblast Growth Factors; GABA Antagonists; Gangliosides; Gene Expression Regulation, Developmental; Glutamic Acid; Kainic Acid; Membrane Potentials; Neurons; O Antigens; Oligodendroglia; Patch-Clamp Techniques; Platelet-Derived Growth Factor; Pregnancy; Quinoxalines; Rats; Rats, Long-Evans; Sodium Channel Blockers; Tetrodotoxin; Tritium | 2009 |
Glutamate uptake shapes low-[Mg2+] induced epileptiform activity in juvenile rat hippocampal slices.
Topics: Aging; Animals; Aspartic Acid; CA3 Region, Hippocampal; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epilepsy; Glutamic Acid; Hippocampus; Kainic Acid; Magnesium; Magnesium Deficiency; Male; Neurons; Neurotransmitter Transport Proteins; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Pyrrolidines; Rats; Rats, Wistar; Synaptic Transmission | 2010 |
Region- and pattern-specific effects of glutamate uptake blockers on epileptiform activity in rat brain slices.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Aspartic Acid; Electrophysiology; Entorhinal Cortex; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Kainic Acid; Male; Neurons; Neurotransmitter Uptake Inhibitors; Rats; Rats, Wistar; Synaptic Transmission | 2010 |
Effect of inhibition of spinal cord glutamate transporters on inflammatory pain induced by formalin and complete Freund's adjuvant.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting, Western; Disease Models, Animal; Formaldehyde; Freund's Adjuvant; Glutamic Acid; Inflammation; Kainic Acid; Male; Nicotinic Acids; Pain; Phosphoserine; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord | 2011 |
Up-regulation of GLT1 reverses the deficit in cortically evoked striatal ascorbate efflux in the R6/2 mouse model of Huntington's disease.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Aspartic Acid; Ceftriaxone; Cerebral Cortex; Corpus Striatum; Electric Stimulation; Excitatory Amino Acid Transporter 2; Extracellular Fluid; Genotype; Huntington Disease; Kainic Acid; Male; Mice; Mice, Transgenic; Microinjections; Transcription, Genetic; Up-Regulation | 2012 |
Glial glutamate transporter and glutamine synthetase regulate GABAergic synaptic strength in the spinal dorsal horn.
Topics: Animals; Aspartic Acid; Astrocytes; Electric Stimulation; Electrophysiological Phenomena; Excitatory Amino Acid Transporter 1; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamine; Kainic Acid; Male; Neuroglia; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Synapses | 2012 |
Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biophysics; Biotinylation; Cells, Cultured; Colforsin; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; Flow Cytometry; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Indoles; Kainic Acid; Long-Term Potentiation; Male; Neurons; Protein Transport; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Valine | 2012 |
Role of the major glutamate transporter GLT1 in nucleus accumbens core versus shell in cue-induced cocaine-seeking behavior.
Topics: Analysis of Variance; Animals; Aspartic Acid; Behavior, Animal; Blotting, Western; Ceftriaxone; Cocaine-Related Disorders; Conditioning, Operant; Cues; Excitatory Amino Acid Transporter 2; Feeding Behavior; Kainic Acid; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence; Substance Withdrawal Syndrome | 2013 |