Page last updated: 2024-09-02

dihydrokainate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

dihydrokainate has been researched along with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid in 6 studies

Compound Research Comparison

Studies
(dihydrokainate)
Trials
(dihydrokainate)
Recent Studies (post-2010)
(dihydrokainate)
Studies
(alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid)
Trials
(alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid)
Recent Studies (post-2010) (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid)
1800462,89911609
1800462403

Protein Interaction Comparison

ProteinTaxonomydihydrokainate (IC50)alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (IC50)
Glutamate receptor 1Rattus norvegicus (Norway rat)0.157
Glutamate receptor 2Rattus norvegicus (Norway rat)0.1765
Glutamate receptor 3Rattus norvegicus (Norway rat)0.1765
Glutamate receptor 4Rattus norvegicus (Norway rat)0.1765
Glutamate receptor 1Mus musculus (house mouse)0.04
Glutamate receptor 2Mus musculus (house mouse)0.04
Glutamate receptor 1Homo sapiens (human)0.1353
Glutamate receptor 2Homo sapiens (human)0.1353
Glutamate receptor 3Homo sapiens (human)0.1353
Glutamate receptor 4Homo sapiens (human)0.1353
Glutamate receptor 4Mus musculus (house mouse)0.04
Glutamate receptor 3Mus musculus (house mouse)0.04

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bouazzaoui, M; Gombos, G; Kannengieser, C; Procksch, O1
Asztely, F; Erdemli, G; Kullmann, DM1
Trussell, LO; Turecek, R1
Attwell, D; Hamann, M; Marie, H; Rossi, DJ1
Artigas, F; Castañé, A; Gasull-Camós, J; Tarrés-Gatius, M1
Armstrong, N; Gouaux, E1

Other Studies

6 other study(ies) available for dihydrokainate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

ArticleYear
Kainic acid, AMPA, and dihydrokainic acid effect on uptake and efflux of D-[3H] aspartic acid in cerebellar slices.
    Neurochemical research, 1996, Volume: 21, Issue:12

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Kinetics; Quinoxalines; Rats; Rats, Wistar; Tetrodotoxin; Tritium

1996
Extrasynaptic glutamate spillover in the hippocampus: dependence on temperature and the role of active glutamate uptake.
    Neuron, 1997, Volume: 18, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport, Active; Diffusion; Electric Stimulation; Evoked Potentials; Glutamates; Guinea Pigs; Hippocampus; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Temperature

1997
Control of synaptic depression by glutamate transporters.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Mar-01, Volume: 20, Issue:5

    Topics: Action Potentials; Alanine Transaminase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Anti-Bacterial Agents; Antihypertensive Agents; Aspartic Acid; ATP-Binding Cassette Transporters; Benzothiadiazines; Chick Embryo; Cochlear Nucleus; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Receptors, AMPA; Synaptic Transmission

2000
Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia.
    The European journal of neuroscience, 2002, Volume: 15, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate

2002
Glial GLT-1 blockade in infralimbic cortex as a new strategy to evoke rapid antidepressant-like effects in rats.
    Translational psychiatry, 2017, 02-21, Volume: 7, Issue:2

    Topics: Affect; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Citalopram; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Kainic Acid; Limbic Lobe; Male; Neuroglia; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Quinoxalines; Raphe Nuclei; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Veratridine

2017
Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.
    Neuron, 2000, Volume: 28, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Binding Sites; Crystallography, X-Ray; Dimerization; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Kainic Acid; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Tertiary; Quinoxalines; Receptors, AMPA; Structure-Activity Relationship; Zinc

2000