dihydroguaiaretic acid has been researched along with lignans in 44 studies
| Studies (dihydroguaiaretic acid) | Trials (dihydroguaiaretic acid) | Recent Studies (post-2010) (dihydroguaiaretic acid) | Studies (lignans) | Trials (lignans) | Recent Studies (post-2010) (lignans) |
|---|---|---|---|---|---|
| 50 | 0 | 23 | 7,024 | 95 | 4,172 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.55) | 18.7374 |
| 1990's | 7 (15.91) | 18.2507 |
| 2000's | 15 (34.09) | 29.6817 |
| 2010's | 20 (45.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, MN; Han, GQ; Hwang, SB | 1 |
| Barth, J; Steinmann, D; Wozel, G | 1 |
| Hirose, M; Ito, N; Kimura, J; Shirai, T; Takaba, K; Yoshida, Y | 1 |
| Chamone, DA; D'Amico, EA; Fries, DM; Monteiro, HP; Neiva, TJ | 1 |
| Alali, F; Asuzu, IU; Hopp, DC; McLaughlin, JL; Njoku, CJ | 1 |
| Lee, DK; Park, S; Yang, CH | 1 |
| Kameoka, H; Kasahara, H; Miyazawa, M; Nakamura, S; Okuno, Y; Oshiro, K; Shimamura, H | 1 |
| Brown, PJ; Fenical, W; Hay, ME; Kubanek, J; Lindquist, N | 1 |
| Chen, N; Pan, XF; Wu, AX; Zhao, YR | 1 |
| Chulia, AJ; Duroux, JL; Filleur, F; Le Bail, JC; Simon, A | 1 |
| GRIEPENTROG, F | 1 |
| Kim, SG; Kim, YC; Ma, CJ; Park, EY; Shin, SM | 1 |
| Kim, J; Kim, SR; Kim, YC; Ma, CJ | 1 |
| Chung, JH; Moon, HI | 1 |
| Kim, YC; Lee, MK; Ma, CJ | 1 |
| Ahn, JS; Jang, JP; Kim, BY; Kim, KA; Na, MK; Oh, WK; Sung, NJ; Yang, S | 1 |
| Jung, JC; Moon, H; Moon, HI | 1 |
| Chen, YG; Fang, A; Hai, LN; Halaweish, F; Liao, XR; Lv, YP; Song, XP | 1 |
| Daley, BJ; Enderson, BL; Gillis, RC; Karlstad, MD; Kestler, DP | 1 |
| Cho, JY; Cho, KY; Choi, GJ; Jang, KS; Kim, JC; Lee, SO; Lim, HK; Son, SW; Sung, ND | 1 |
| Chang, HW; Haa, K; Hong, TG; Hwang, NK; Kim, DH; Kim, JC; Kim, JH; Moon, TC; Seo, CS; Son, JK | 1 |
| Akiyama, J; Akiyama, K; Kawaguchi, Y; Kishida, T; Maruyama, M; Masuda, T; Ohuchi, M; Someya, T; Sugahara, T; Tominaga, S; Yamauchi, S; Yamawaki, M | 1 |
| Avery, VM; Barnes, EC; Davis, RA; Healy, PC; Longden, J | 1 |
| Akiyama, K; Kawaguchi, Y; Kishida, T; Koba, Y; Maruyama, M; Masuda, K; Nishiwaki, H; Sugahara, T; Yamauchi, S | 1 |
| Chen, HS; Peng, ZG; Xiao, PG; Xu, LJ; Ye, WC | 1 |
| Akamatsu, M; Hasebe, A; Kawaguchi, Y; Nishiwaki, H; Shuto, Y; Yamauchi, S | 1 |
| Hwang, JK; Kim, D; Kim, KJ; Lee, KE; Lee, MS | 1 |
| Hasebe, A; Nishiwaki, H; Shuto, Y; Wukirsari, T; Yamauchi, S | 1 |
| Akiyama, K; Hasebe, A; Kishida, T; Nishiwaki, H; Sugahara, T; Yamauchi, S | 1 |
| Akiyama, K; Kishida, T; Nishi, K; Nishiwaki, H; Sugahara, T; Wukirsari, T; Yamauchi, S | 1 |
| Choi, YJ; Je, YT; Lee, BH; Lee, KY; Park, HJ; Park, S; Park, SJ; Shin, KJ; Sim, WC; Sung, SH; Yin, HQ | 1 |
| Kim, EC; Kim, TJ; Kim, WJ; Song, MC | 1 |
| Balderas-Rentería, I; Clemente-Soto, AF; del Rayo Camacho-Corona, M; Garza-González, E; Rivera, G; Segura-Cabrera, A | 1 |
| He, QX; Liu, HT; Liu, KC; Qi, YD; Wang, ZM; Xiao, PG; Zhang, BG; Zhang, J | 1 |
| Jeon, JS; Kim, SK; Kim, YM; Lee, BH; Lee, JY; Oh, SJ; Ryu, CS | 1 |
| Kishida, T; Nishi, K; Nishiwaki, H; Shuto, Y; Sugahara, T; Tabara, Y; Yamauchi, S | 1 |
| Cai, Q; Du, SS; Zheng, LS | 1 |
| Choi, MS; Choi, Y; Jeon, S; Jeong, HJ; Kang, TH; Oh, ST; Shin, HM | 1 |
| Cho, ES; Kim, TI; Kwon, HJ; Seo, CS; Son, HY; Son, JK; Song, JW; Won, YS | 1 |
| Akiyama, K; Nakazaki, S; Nishiwaki, H; Yamauchi, S | 1 |
| Camacho-Corona, MDR; Favela-Hernández, JMJ; García, A; Garza-González, E; Miranda, LD; Reyes-Melo, K; Rivas-Galindo, VM; Romo-Mancillas, A; Vargas-Villarreal, J | 1 |
| Choi, KM; Hong, JT; Jeong, H; Jung, WB; Kim, GY; Lee, A; Lee, JH; Lee, MK; Roh, YS; Sung, SH; Yoo, HS | 1 |
| Gao, SM; Guo, YJ; Liu, HT; Zhang, BG | 1 |
| Brito, JR; da Costa-Silva, TA; Ferreira, EA; Lago, JHG; Tempone, AG | 1 |
44 other study(ies) available for dihydroguaiaretic acid and lignans
| Article | Year |
|---|---|
[The investigation of lignans from Sargentodoxa cuneata (Oliv) Rehd et Wils].
Topics: Chemical Phenomena; Chemistry; Guaiacol; Lignans; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Plant Extracts; Plants, Medicinal; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1986 |
Anti-inflammatory activity of croconazole, a broad-spectrum antimycotic agent, in the arachidonic acid-induced mouse ear swelling test.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Arachidonic Acid; Ear, External; Edema; Female; Guaiacol; Imidazoles; Lignans; Lipoxygenase Inhibitors; Mice; Mice, Inbred Strains | 1995 |
Effects of n-tritriacontane-16,18-dione, curcumin, chlorphyllin, dihydroguaiaretic acid, tannic acid and phytic acid on the initiation stage in a rat multi-organ carcinogenesis model.
Topics: Aminobiphenyl Compounds; Animals; Antimutagenic Agents; Antineoplastic Agents; Antioxidants; Carcinogens; Chlorophyllides; Curcumin; Diethylnitrosamine; Guaiacol; Hydrolyzable Tannins; Lignans; Liver Neoplasms; Lung Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Paraffin; Phytic Acid; Precancerous Conditions; Rats; Rats, Inbred F344 | 1997 |
Aluminum induces lipid peroxidation and aggregation of human blood platelets.
Topics: Adult; Aluminum; Guaiacol; Humans; L-Lactate Dehydrogenase; Lignans; Lipid Peroxidation; Luminescent Measurements; Platelet Aggregation; Propyl Gallate; Ristocetin; Salicylates | 1997 |
Dihydroguaiaretic acid: a bioactive component of the stem bark of Pycnanthus angolensis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Caenorhabditis elegans; Decapoda; Guaiacol; Humans; Lignans; Plant Stems; Plants, Medicinal; Trees; Tumor Cells, Cultured | 1997 |
Inhibition of fos-jun-DNA complex formation by dihydroguaiaretic acid and in vitro cytotoxic effects on cancer cells.
Topics: Dimerization; Guaiacol; Humans; Lignans; Masoprocol; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Transcription Factor AP-1; Tumor Cells, Cultured | 1998 |
Suppression of the SOS-inducing activity of Trp-P-1 and aflatoxin B1 by meso-dihydroguaiaretic acid from Machilus thunbergii in the Salmonella typhimurium TA1535/pSK1002 umu test.
Topics: Aflatoxin B1; Carbolines; Chloroform; DNA Damage; Gas Chromatography-Mass Spectrometry; Guaiacol; Lauraceae; Lignans; Magnetic Resonance Spectroscopy; Mutagens; Plant Extracts; Salmonella typhimurium; SOS Response, Genetics | 1998 |
Two antifeedant lignans from the freshwater macrophyte Saururus cernuus.
Topics: Animals; Astacoidea; Feeding Behavior; Fresh Water; Guaiacol; Lignans; Magnoliopsida; Models, Molecular; Molecular Conformation; Molecular Structure | 2000 |
[Total synthesis of nordihydroguaiaretic acid].
Topics: Furans; Guaiacol; Lignans; Masoprocol; Molecular Structure; Plants, Medicinal | 1997 |
Antiproliferative, anti-aromatase, anti-17beta-HSD and antioxidant activities of lignans isolated from Myristica argentea.
Topics: 17-Hydroxysteroid Dehydrogenases; Antineoplastic Agents, Phytogenic; Antioxidants; Aromatase Inhibitors; Cell Division; Guaiacol; Humans; Lignans; Magnetic Resonance Spectroscopy; Myristicaceae; Plant Extracts; Tumor Cells, Cultured | 2001 |
[Allergy studies with some simple chemical substances. 7. Nor-dihydroguaiaretic acid].
Topics: Guaiac; Guaiacol; Humans; Hypersensitivity; Lignans | 1961 |
meso-dihydroguaiaretic acid from Machilus thunbergii down-regulates TGF-beta1 gene expression in activated hepatic stellate cells via inhibition of AP-1 activity.
Topics: Animals; DNA Primers; Dose-Response Relationship, Drug; Down-Regulation; Guaiacol; Immunoblotting; Immunohistochemistry; Lauraceae; Lignans; Liver; Male; Phytotherapy; Plant Bark; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Meso-dihydroguaiaretic acid and licarin A of Machilus thunbergii protect against glutamate-induced toxicity in primary cultures of a rat cortical cells.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Glutamic Acid; Glutathione; Guaiacol; Lauraceae; Lignans; Nitric Oxide; Peroxides; Rats; Rats, Sprague-Dawley | 2005 |
Meso-dihydroguaiaretic acid from Machilus thunbergii SIEB et ZUCC., and its effects on the expression of matrix metalloproteinase-2, 9 cause by ultraviolet irradiated cultured human keratinocyte cells (HaCaT).
Topics: Cell Line; Gene Expression Regulation, Enzymologic; Glyceraldehyde-3-Phosphate Dehydrogenases; Guaiacol; Humans; Keratinocytes; Lauraceae; Lignans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Nitroblue Tetrazolium; Reverse Transcriptase Polymerase Chain Reaction; RNA; Ultraviolet Rays | 2005 |
meso-Dihydroguaiaretic acid attenuates the neurotoxic effect of staurosporine in primary rat cortical cultures.
Topics: Analysis of Variance; Animals; Apoptosis; Calcium; Caspase 3; Caspases; Cells, Cultured; Cerebral Cortex; Cytochromes c; Dansyl Compounds; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Galactosamine; Guaiacol; Lignans; Neurons; Neurotoxins; Peroxides; Rats; Rats, Sprague-Dawley; Staurosporine | 2006 |
Inhibition of protein tyrosine phosphatase 1B by lignans from Myristica fragrans.
Topics: Animals; Cell Line; Chemical Fractionation; Enzyme Inhibitors; Granulocytes; Guaiacol; Inhibitory Concentration 50; Lignans; Mice; Myristica; Phosphorylation; Plant Extracts; Pollen; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Receptor, Insulin | 2006 |
Effect of meso-dihydroguaiaretic acid from Machilus thunbergii Sieb et Zucc on MMP-1 expression in heat shock-induced cultured primary human fibroblasts.
Topics: Cell Proliferation; Cells, Cultured; Fibroblasts; Guaiacol; Heat-Shock Response; Hot Temperature; Humans; Lauraceae; Lignans; Matrix Metalloproteinase 1; Plant Extracts | 2006 |
Compounds with DNA cleaving activity from Kadsura ananosma.
Topics: Cell Line, Tumor; Chalcones; DNA; DNA, Superhelical; Guaiacol; HeLa Cells; Humans; Kadsura; Leukemia; Lignans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nucleic Acid Conformation; Plant Bark; Plant Stems | 2006 |
Regulation of apoptosis in eicosapentaenoic acid-treated HL-60 cells.
Topics: Apoptosis; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Cyclooxygenase Inhibitors; Eicosapentaenoic Acid; Enzyme Inhibitors; Fatty Acids, Unsaturated; Flavanones; Guaiacol; HL-60 Cells; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indoles; Leukotriene B4; Lignans; Lipoxygenase Inhibitors; Neutrophils; Respiratory Distress Syndrome | 2007 |
Isolation and antifungal activity of lignans from Myristica fragrans against various plant pathogenic fungi.
Topics: Antifungal Agents; Guaiacol; Lignans; Mass Spectrometry; Microbial Sensitivity Tests; Myristica; Plants; Seeds | 2007 |
Meso-dihydroguaiaretic acid isolated from Saururus chinensis inhibits cyclooxygenase-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Bone Marrow Cells; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Guaiacol; Lignans; Lipoxygenase Inhibitors; Male; Mast Cells; Mice; Mice, Inbred BALB C; Saururaceae | 2008 |
Antioxidant activity of butane type lignans, secoisolariciresinol, dihydroguaiaretic acid, and 7,7'-oxodihydroguaiaretic acid.
Topics: Butanes; Butylene Glycols; Free Radical Scavengers; Guaiacol; Lignans; Lipoxygenase Inhibitors; Oxidation-Reduction; Stereoisomerism | 2008 |
Isolation, structure elucidation and cytotoxic evaluation of endiandrin B from the Australian rainforest plant Endiandra anthropophagorum.
Topics: Antineoplastic Agents, Phytogenic; Australia; Cell Line, Tumor; Crystallography, X-Ray; Cyclobutanes; Guaiacol; Humans; Inhibitory Concentration 50; Lauraceae; Lignans; Magnetic Resonance Spectroscopy; Plant Roots; Plants, Medicinal | 2009 |
Antimicrobial activity of stereoisomers of butane-type lignans.
Topics: Anti-Infective Agents; Bacteria; Butanes; Foodborne Diseases; Fungi; Guaiacol; Lignans; Plant Diseases; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 2009 |
[Effective components against HIV-1 replicative enzymes isolated from plants].
Topics: Alkaloids; Anti-HIV Agents; Drugs, Chinese Herbal; Flavones; Guaiacol; HIV Integrase; HIV Protease; HIV Reverse Transcriptase; Lignans; Plants, Medicinal; Ranunculaceae; Rutaceae; Schisandraceae; Triterpenes | 2010 |
Larvicidal activity of (-)-dihydroguaiaretic acid derivatives against Culex pipiens.
Topics: Animals; Butylene Glycols; Culex; Disease Vectors; Guaiacol; Hydrophobic and Hydrophilic Interactions; Hydroxylation; Insect Control; Insecticides; Larva; Lethal Dose 50; Lignans; Stereoisomerism; Structure-Activity Relationship | 2011 |
meso-Dihydroguaiaretic acid inhibits hepatic lipid accumulation by activating AMP-activated protein kinase in human HepG2 cells.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Cell Culture Techniques; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Dyslipidemias; Enzyme Activation; Enzyme Inhibitors; Fatty Liver; Guaiacol; Hep G2 Cells; Humans; Hypolipidemic Agents; Insulin Resistance; Lignans; Lipid Metabolism; Liver; Molecular Targeted Therapy; Myristica; Non-alcoholic Fatty Liver Disease; Phosphorylation; Phytotherapy; Plant Extracts; Pyrazoles; Pyrimidines | 2011 |
First discovery of insecticidal activity of 9,9'-epoxylignane and dihydroguaiaretic acid against houseflies and the structure-activity relationship.
Topics: Animals; Epoxy Compounds; Guaiacol; Houseflies; Insecticides; Lignans; Plant Extracts; Stereoisomerism; Structure-Activity Relationship | 2013 |
Quantitative structure-activity relationship analysis of antifungal (+)-dihydroguaiaretic acid using 7-phenyl derivatives.
Topics: Alternaria; Fungicides, Industrial; Guaiacol; Lignans; Quantitative Structure-Activity Relationship | 2013 |
Cytotoxic activity of dietary lignan and its derivatives: structure-cytotoxic activity relationship of dihydroguaiaretic acid.
Topics: Animals; Cell Proliferation; Cell Survival; Chlorocebus aethiops; Cytotoxins; Guaiacol; HL-60 Cells; Humans; Lignans; Molecular Structure; Structure-Activity Relationship; Vero Cells | 2014 |
LXR-α antagonist meso-dihydroguaiaretic acid attenuates high-fat diet-induced nonalcoholic fatty liver.
Topics: Animals; Base Sequence; Cell Line, Tumor; Diet, High-Fat; DNA Primers; Fatty Liver; Guaiacol; Humans; Lignans; Lipogenesis; Liver X Receptors; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Non-alcoholic Fatty Liver Disease; Orphan Nuclear Receptors | 2014 |
Meso-dihydroguaiaretic acid inhibits rat aortic vascular smooth muscle cell proliferation by suppressing phosphorylation of platelet-derived growth factor receptor beta.
Topics: Animals; Aorta; Becaplermin; Cell Proliferation; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Guaiacol; JNK Mitogen-Activated Protein Kinases; Lignans; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phospholipase C gamma; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Rats; Signal Transduction | 2014 |
Potential mechanism of action of meso-dihydroguaiaretic acid on Mycobacterium tuberculosis H37Rv.
Topics: Antitubercular Agents; Binding Sites; Down-Regulation; Gene Expression Regulation, Bacterial; Genes, Bacterial; Guaiacol; Lignans; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Up-Regulation | 2014 |
[Chemical constituents of Kadsura oblongifolia and evaluation of their toxicity].
Topics: Animals; Embryo, Nonmammalian; Guaiacol; Kadsura; Lignans; Plant Extracts; Quercetin; Triterpenes; Zebrafish | 2014 |
Metabolic characterization of meso-dihydroguaiaretic acid in liver microsomes and in mice.
Topics: Animals; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 Enzyme System; Glucuronosyltransferase; Guaiacol; Half-Life; Humans; Lauraceae; Lignans; Male; Mice; Mice, Inbred ICR; Microsomes, Liver | 2015 |
Acute larvicidal activity against mosquitoes and oxygen consumption inhibitory activity of dihydroguaiaretic acid derivatives.
Topics: Animals; Culex; Guaiacol; Insecticides; Larva; Lignans; Molecular Structure; Oxygen | 2015 |
[Study on chemical constituents from Schisandra chinensis stem].
Topics: Cyclooctanes; Guaiacol; Lignans; Phytochemicals; Plant Stems; Polycyclic Compounds; Schisandra; Sitosterols | 2014 |
Meso-dihydroguaiaretic acid induces apoptosis and inhibits cell migration via p38 activation and EGFR/Src/intergrin β3 downregulation in breast cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; ErbB Receptors; Female; Genes, src; Guaiacol; Humans; Integrin beta3; Lignans; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; p38 Mitogen-Activated Protein Kinases | 2015 |
meso-Dihydroguaiaretic acid attenuates airway inflammation and mucus hypersecretion in an ovalbumin-induced murine model of asthma.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Cell Movement; Chemokine CCL2; Cytokines; Female; Guaiacol; Humans; Immunoglobulin E; Lignans; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; NF-kappa B; Pneumonia; Saururaceae; Th2 Cells; Vascular Cell Adhesion Molecule-1 | 2016 |
Structure-Antifungal Activity Relationship of Fluorinated Dihydroguaiaretic Acid Derivatives and Preventive Activity against Alternaria alternata Japanese Pear Pathotype.
Topics: Alternaria; Fungicides, Industrial; Guaiacol; Lignans; Plant Diseases; Pyrus; Structure-Activity Relationship | 2017 |
meso-Dihydroguaiaretic acid derivatives with antibacterial and antimycobacterial activity.
Topics: Animals; Anti-Bacterial Agents; Cell Survival; Chlorocebus aethiops; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Gram-Positive Bacteria; Guaiacol; Lignans; Microbial Sensitivity Tests; Molecular Structure; Quantitative Structure-Activity Relationship; Vero Cells | 2017 |
Enhancement of Glucose Uptake by Meso-Dihydroguaiaretic Acid through GLUT4 Up-Regulation in 3T3-L1 Adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Glucose; Glucose Transporter Type 4; Guaiacol; Lignans; Mice; PPAR gamma; Up-Regulation | 2017 |
[Chemical Constituents from Stems of Kadsura longipedunculata].
Topics: Chromatography; Guaiacol; Kadsura; Lignans; Molecular Structure; Plant Extracts; Plant Stems | 2016 |
Dibenzylbutane neolignans from Saururus cernuus L. (Saururaceae) displayed anti-Trypanosoma cruzi activity via alterations in the mitochondrial membrane potential.
Topics: Animals; Brazil; Cells, Cultured; Guaiacol; Lignans; Macrophages, Peritoneal; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Molecular Structure; Phytochemicals; Plant Leaves; Reactive Oxygen Species; Saururaceae; Trypanocidal Agents; Trypanosoma cruzi | 2019 |