dihydroergotoxine and cyanopindolol

dihydroergotoxine has been researched along with cyanopindolol* in 2 studies

Other Studies

2 other study(ies) available for dihydroergotoxine and cyanopindolol

Article	Year
Cocaine selectively inhibits beta-adrenergic receptor binding in pregnant human myometrium. American journal of obstetrics and gynecology, 1993, Volume: 169, Issue:3 This study evaluated the in vitro effects of cocaine on the binding characteristics of alpha- and beta-adrenergic receptors from pregnant human myometrium.. By means of membrane fractions from myometrium obtained from 26 women at term undergoing cesarean section, equilibrium binding assays were performed with tritiated dihydroergocryptine for alpha-adrenergic receptors and iodine 125-cyanopindolol for beta-adrenergic receptors. Equilibrium competition curves were determined with and without cocaine. Results were compared by one-way analysis of variance.. Cocaine inhibited beta-adrenergic receptor binding (inhibition constant = 132 mumol/L) but had little effect on alpha-adrenergic receptor binding (inhibition constant = 1.63 mmol/L). Benzoylecgonine, a stable metabolite of cocaine, had no effect on binding to either receptor.. Cocaine selectively inhibits myometrial beta-adrenergic receptor binding. This may alter the contractile equilibrium of the pregnant uterus and could explain, in part, the association of cocaine abuse with premature delivery. Topics: Adrenergic beta-Antagonists; Binding, Competitive; Cocaine; Dihydroergotoxine; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Isoproterenol; Least-Squares Analysis; Molecular Structure; Myometrium; Pindolol; Pregnancy; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta	1993
Adrenoceptor and imipramine receptor binding during the menstrual cycle. Acta psychiatrica Scandinavica, 1988, Volume: 78, Issue:3 The binding characteristics of platelet alpha 2-adrenoceptors, lymphocyte beta 2-adrenoceptors and platelet imipramine receptors were studied in five women during their menstrual cycle. A significant cyclic variation in the number of beta 2-adrenoceptor sites on intact lymphocytes was found during the menstrual cycle, while binding to alpha 2-adrenoceptors and imipramine receptors remained unchanged. Topics: Adult; Blood Platelets; Carrier Proteins; Dihydroergotoxine; Female; Humans; Imipramine; Lymphocytes; Menstrual Cycle; Pindolol; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Drug; Receptors, Neurotransmitter	1988

Article

Year

Cocaine selectively inhibits beta-adrenergic receptor binding in pregnant human myometrium.

American journal of obstetrics and gynecology, 1993, Volume: 169, Issue:3

This study evaluated the in vitro effects of cocaine on the binding characteristics of alpha- and beta-adrenergic receptors from pregnant human myometrium.. By means of membrane fractions from myometrium obtained from 26 women at term undergoing cesarean section, equilibrium binding assays were performed with tritiated dihydroergocryptine for alpha-adrenergic receptors and iodine 125-cyanopindolol for beta-adrenergic receptors. Equilibrium competition curves were determined with and without cocaine. Results were compared by one-way analysis of variance.. Cocaine inhibited beta-adrenergic receptor binding (inhibition constant = 132 mumol/L) but had little effect on alpha-adrenergic receptor binding (inhibition constant = 1.63 mmol/L). Benzoylecgonine, a stable metabolite of cocaine, had no effect on binding to either receptor.. Cocaine selectively inhibits myometrial beta-adrenergic receptor binding. This may alter the contractile equilibrium of the pregnant uterus and could explain, in part, the association of cocaine abuse with premature delivery.

Topics: Adrenergic beta-Antagonists; Binding, Competitive; Cocaine; Dihydroergotoxine; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Isoproterenol; Least-Squares Analysis; Molecular Structure; Myometrium; Pindolol; Pregnancy; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta

1993

Adrenoceptor and imipramine receptor binding during the menstrual cycle.

Acta psychiatrica Scandinavica, 1988, Volume: 78, Issue:3

The binding characteristics of platelet alpha 2-adrenoceptors, lymphocyte beta 2-adrenoceptors and platelet imipramine receptors were studied in five women during their menstrual cycle. A significant cyclic variation in the number of beta 2-adrenoceptor sites on intact lymphocytes was found during the menstrual cycle, while binding to alpha 2-adrenoceptors and imipramine receptors remained unchanged.

Topics: Adult; Blood Platelets; Carrier Proteins; Dihydroergotoxine; Female; Humans; Imipramine; Lymphocytes; Menstrual Cycle; Pindolol; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Drug; Receptors, Neurotransmitter

1988