Page last updated: 2024-09-02

dihydroergocryptine and levodopa

dihydroergocryptine has been researched along with levodopa in 4 studies

Compound Research Comparison

Studies (dihydroergocryptine)	Trials (dihydroergocryptine)	Recent Studies (post-2010) (dihydroergocryptine)	Studies (levodopa)	Trials (levodopa)	Recent Studies (post-2010) (levodopa)
21	8	2	17,774	1,900	4,946

Protein Interaction Comparison

Protein	Taxonomy	levodopa (IC50)
integrase, partial	Human immunodeficiency virus 1	0.5939
lens epithelium-derived growth factor p75	Homo sapiens (human)	0.5939
Epidermal growth factor receptor	Homo sapiens (human)	2.88
Tyrosine-protein kinase Lck	Homo sapiens (human)	3.729
Tyrosine-protein kinase Fyn	Homo sapiens (human)	2.146
Polyunsaturated fatty acid lipoxygenase ALOX15	Oryctolagus cuniculus (rabbit)	2.258

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gasser, T; Pöpperl, G; Ruzicka, E; Schwarz, J; Storch, A; Tatsch, K	1
Magnani, P; Mailland, E; Ottillinger, B	1
Goetz, CG; Poewe, W; Rascol, O; Sampaio, C	1
Gille, G; Radad, K; Rausch, WD; Reichmann, H	1

Reviews

1 review(s) available for dihydroergocryptine and levodopa

Article	Year
Evidence-based medical review update: pharmacological and surgical treatments of Parkinson's disease: 2001 to 2004. Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:5 Topics: Amantadine; Antiparkinson Agents; Apomorphine; Benzophenones; Benzothiazoles; Bromocriptine; Cabergoline; Catechol O-Methyltransferase Inhibitors; Deep Brain Stimulation; Dihydroergocryptine; Ergolines; Fetal Tissue Transplantation; Globus Pallidus; Humans; Indans; Indoles; Levodopa; Lisuride; Mesencephalon; Monoamine Oxidase Inhibitors; Neurosurgical Procedures; Nitrophenols; Parkinson Disease; Pergolide; Piribedil; Pramipexole; Selegiline; Thiazoles; Tolcapone	2005

Article

Year

Evidence-based medical review update: pharmacological and surgical treatments of Parkinson's disease: 2001 to 2004.

Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:5

Topics: Amantadine; Antiparkinson Agents; Apomorphine; Benzophenones; Benzothiazoles; Bromocriptine; Cabergoline; Catechol O-Methyltransferase Inhibitors; Deep Brain Stimulation; Dihydroergocryptine; Ergolines; Fetal Tissue Transplantation; Globus Pallidus; Humans; Indans; Indoles; Levodopa; Lisuride; Mesencephalon; Monoamine Oxidase Inhibitors; Neurosurgical Procedures; Nitrophenols; Parkinson Disease; Pergolide; Piribedil; Pramipexole; Selegiline; Thiazoles; Tolcapone

2005

Trials

2 trial(s) available for dihydroergocryptine and levodopa

Article	Year
Comparison of alpha-dihydroergocryptine and levodopa monotherapy in Parkinson's disease: assessment of changes in DAT binding with [123I]IPT SPECT. Journal of neural transmission (Vienna, Austria : 1996), 2004, Volume: 111, Issue:8 Topics: Adolescent; Aged; Caudate Nucleus; Dihydroergocryptine; Dopamine Plasma Membrane Transport Proteins; Double-Blind Method; Female; Follow-Up Studies; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Neostriatum; Nerve Tissue Proteins; Parkinson Disease; Putamen; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Tropanes	2004
Alpha-dihydroergocryptine in the long-term therapy of Parkinson's disease. Arzneimittel-Forschung, 2004, Volume: 54, Issue:10 Topics: Aged; Antiparkinson Agents; Dihydroergocryptine; Female; Gait Disorders, Neurologic; Humans; Levodopa; Male; Muscle Rigidity; Parkinson Disease; Posture; Psychomotor Performance; Speech Disorders; Tremor	2004

Article

Year

Comparison of alpha-dihydroergocryptine and levodopa monotherapy in Parkinson's disease: assessment of changes in DAT binding with [123I]IPT SPECT.

Journal of neural transmission (Vienna, Austria : 1996), 2004, Volume: 111, Issue:8

Topics: Adolescent; Aged; Caudate Nucleus; Dihydroergocryptine; Dopamine Plasma Membrane Transport Proteins; Double-Blind Method; Female; Follow-Up Studies; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Neostriatum; Nerve Tissue Proteins; Parkinson Disease; Putamen; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Tropanes

2004

Alpha-dihydroergocryptine in the long-term therapy of Parkinson's disease.

Arzneimittel-Forschung, 2004, Volume: 54, Issue:10

Topics: Aged; Antiparkinson Agents; Dihydroergocryptine; Female; Gait Disorders, Neurologic; Humans; Levodopa; Male; Muscle Rigidity; Parkinson Disease; Posture; Psychomotor Performance; Speech Disorders; Tremor

2004

Other Studies

1 other study(ies) available for dihydroergocryptine and levodopa

Article	Year
Synergistic effect of alpha-dihydroergocryptine and L-dopa or dopamine on dopaminergic neurons in primary culture. Journal of neural transmission (Vienna, Austria : 1996), 2006, Volume: 113, Issue:9 Topics: 1-Methyl-4-phenylpyridinium; Animals; Carbidopa; Cell Count; Cells, Cultured; Dihydroergocryptine; Dopamine; Dopamine Agents; Dopamine Antagonists; Drug Synergism; Female; Lactic Acid; Levodopa; Mice; Neuroglia; Neurons; Pregnancy; Sulpiride; Tyrosine 3-Monooxygenase	2006

Article

Year

Synergistic effect of alpha-dihydroergocryptine and L-dopa or dopamine on dopaminergic neurons in primary culture.

Journal of neural transmission (Vienna, Austria : 1996), 2006, Volume: 113, Issue:9

Topics: 1-Methyl-4-phenylpyridinium; Animals; Carbidopa; Cell Count; Cells, Cultured; Dihydroergocryptine; Dopamine; Dopamine Agents; Dopamine Antagonists; Drug Synergism; Female; Lactic Acid; Levodopa; Mice; Neuroglia; Neurons; Pregnancy; Sulpiride; Tyrosine 3-Monooxygenase

2006