Page last updated: 2024-09-02

dihydroergocryptine and ergotamine

dihydroergocryptine has been researched along with ergotamine in 2 studies

Compound Research Comparison

Studies
(dihydroergocryptine)
Trials
(dihydroergocryptine)
Recent Studies (post-2010)
(dihydroergocryptine)
Studies
(ergotamine)
Trials
(ergotamine)
Recent Studies (post-2010) (ergotamine)
5022,352103103

Protein Interaction Comparison

ProteinTaxonomydihydroergocryptine (IC50)ergotamine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.056
Tyrosine-protein kinase LckHomo sapiens (human)6.499
Tyrosine-protein kinase FynHomo sapiens (human)3.16
Beta-2 adrenergic receptorHomo sapiens (human)2.761
Beta-1 adrenergic receptorHomo sapiens (human)4.142
Cytochrome P450 3A4Homo sapiens (human)1
Alpha-2A adrenergic receptorHomo sapiens (human)0.0021
D(2) dopamine receptorHomo sapiens (human)0.0043
Alpha-2B adrenergic receptorHomo sapiens (human)0.0038
Alpha-2C adrenergic receptorHomo sapiens (human)0.012
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0008
D(1A) dopamine receptorHomo sapiens (human)1.728
Thromboxane-A synthase Homo sapiens (human)3.064
Alpha-1D adrenergic receptorHomo sapiens (human)0.049
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0065
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.056
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0008
D(3) dopamine receptorHomo sapiens (human)0.0043
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0035
5-hydroxytryptamine receptor 6Homo sapiens (human)0.002

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dantzig, AH; Ekins, S; Kim, RB; Lan, LB; Leake, BF; Schuetz, EG; Schuetz, JD; Shepard, RL; Wikel, JH; Winter, MA; Wrighton, SA; Yasuda, K1
Furuya, K; Lan, LB; Sanglard, D; Schuetz, EG; Schuetz, JD; Yasuda, K1

Other Studies

2 other study(ies) available for dihydroergocryptine and ergotamine

ArticleYear
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein.
    Molecular pharmacology, 2002, Volume: 61, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Ergonovine; Fluoxetine; Humans; Models, Molecular; Oxytocics; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Swine; Transfection; Vinblastine

2002
Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroergocryptine; Drug Interactions; Enzyme Inhibitors; Fluconazole; Humans; Mice; Mice, Knockout; Microsomes, Liver; Oxidoreductases, N-Demethylating; Recombinant Proteins; Reserpine; Swine; Tissue Distribution; Transfection; Vinblastine

2002