dihydrocodeine and morphine

dihydrocodeine has been researched along with morphine in 47 studies

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199013 (27.66)18.7374
1990's15 (31.91)18.2507
2000's8 (17.02)29.6817
2010's10 (21.28)24.3611
2020's1 (2.13)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Antonilli, L; Bianco, A; Guarcini, L; Nencini, P; Nicoletti, R; Sabatini, G; Sanasi, F; Togna, AR; Togna, GI; Venditti, A1
Bellman, K; Knegtel, RM; Settimo, L1
Kamei, J; Kasuya, Y1
Masukawa, Y; Misawa, M; Suzuki, T1
Aitken, HA; Clark, EC; Dimitri, W; Kenny, GN; McArdle, CS1
Kamei, J; Kasuya, Y; Mori, T; Ogawa, M1
Sica, DA; Wolfert, AI1
Bateman, DN; Blain, PG; Lane, RJ; Rawlins, MD1
Rambohul, E; Ruprah, M1
Käferstein, H; Staak, M; Sticht, G1
Bedford, KR; White, PC1
McQuay, H; Moore, A1
Kigoshi, S; Kitajima, K1
Fromm, MF; Hofmann, U; Johnson, S; Mikus, G1
Braithwaite, RA; George, S1
Mignat, C; Wille, U; Ziegler, A1
Käferstein, H; Schmidt, P; Sticht, G1
Fey, P; Moeller, MR; Wennig, R1
Daldrup, T; Musshoff, F1
Denk, R; Raff, I; Sachs, H1
Stoneham, MD; Walters, FJ1
Pötsch, L; Skopp, G1
Alvarez Requejo, A; Caro-Patón, T; Carvajal, A; García del Pozo, J; Martín Arias, LH; Martín de Diego, I; Rueda, AM1
McQuay, HJ; Moore, RA1
Bohrer, A; Koenig, J; Nowatzke, W; Saunders, A; Turk, J; Zeng, J1
Ariniemi, K; Lillsunde, P; Mykkänen, S; Seppälä, J1
Jussila, M; Porras, SP; Riekkola, ML; Sinervo, K1
Benítez Del Rosario, MA; Cabrejas Sánchez, A; Fernández Díaz, R; Pérez Suárez, MC1
Braithwaite, R; George, S; Meadway, C1
BEECHER, HK; GRAVENSTEIN, JS; ISAACS, JP; SMITH, GM; SPHIRE, RD1
BELLVILLE, JW; HOUDE, RW; SEED, JC; WALLENSTEIN, SL1
LUND, I1
FISCHER, E; STAMBURGO, M; SZABO, JL1
Greiner, E; May, EL; Rice, KC; Selley, DE; Thompson, CM; Wojno, H1
Reichel, S; Stimpfl, T1
Fujita, T; Kumamoto, E; Mizuta, K; Nakatsuka, T1
RAPOPORT, H1
Alford, I; Shan, X; Tiscione, NB; Yeatman, DT1
Daldrup, T; Lerch, O; Temme, O1
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M1
Geffe, M; Opatz, T1
Agüera, A; Campos-Mañas, MC; Ferrer, I; Sánchez Pérez, JA; Thurman, EM1
Copeland, CS; Rees, P; Reynolds, LM; Rock, KL1

Reviews

3 review(s) available for dihydrocodeine and morphine

ArticleYear
Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review.
    Health technology assessment (Winchester, England), 1998, Volume: 2, Issue:12

    Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Codeine; Dextropropoxyphene; Diclofenac; Humans; Ibuprofen; Morphine; Ondansetron; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Randomized Controlled Trials as Topic; Reproducibility of Results; Tramadol; Transcutaneous Electric Nerve Stimulation; Treatment Outcome

1998
"Weak" opioid analgesics. Codeine, dihydrocodeine and tramadol: no less risky than morphine.
    Prescrire international, 2016, Volume: 25, Issue:168

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Codeine; Dose-Response Relationship, Drug; Humans; Morphine; Respiration; Tramadol

2016
Highlighting the hidden dangers of a 'weak' opioid: Deaths following use of dihydrocodeine in England (2001-2020).
    Drug and alcohol dependence, 2022, 04-01, Volume: 233

    Topics: Analgesics, Opioid; Codeine; Drug Overdose; England; Heroin; Humans; Morphine; Substance-Related Disorders; Suicide

2022

Trials

1 trial(s) available for dihydrocodeine and morphine

ArticleYear
Evaluation of two formulations of dihydrocodeine using patient-controlled analgesia.
    Anaesthesia, 1990, Volume: 45, Issue:7

    Topics: Adolescent; Adult; Aged; Analgesia; Codeine; Coronary Artery Bypass; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphine; Nausea; Pain, Postoperative; Randomized Controlled Trials as Topic; Self Administration; Vomiting

1990

Other Studies

43 other study(ies) available for dihydrocodeine and morphine

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Pivaloylcodeine, a new codeine derivative, for the inhibition of morphine glucuronidation. An in vitro study in the rat.
    Bioorganic & medicinal chemistry, 2013, Dec-15, Volume: 21, Issue:24

    Topics: Animals; Codeine; Dose-Response Relationship, Drug; Hepatocytes; Kinetics; Male; Microsomes, Liver; Molecular Structure; Morphine Derivatives; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Antitussive effects of Ca2+ channel antagonists.
    European journal of pharmacology, 1992, Feb-25, Volume: 212, Issue:1

    Topics: Animals; Antitussive Agents; Calcium Channel Blockers; Capsaicin; Codeine; Cough; Dextromethorphan; Drug Interactions; Drug Synergism; Flunarizine; Guinea Pigs; Male; Morphine; Nifedipine; Verapamil

1992
Drug interactions in the reinforcing effects of over-the-counter cough syrups.
    Psychopharmacology, 1990, Volume: 102, Issue:4

    Topics: Animals; Antitussive Agents; Benzazepines; Chlorpheniramine; Codeine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Male; Morphine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Substance-Related Disorders

1990
Subsensitivity to the cough-depressant effects of opioid and nonopioid antitussives in morphine-dependent rats: relationship to central serotonin function.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:3

    Topics: Animals; Antitussive Agents; Brain Stem; Codeine; Cough; Dextromethorphan; Levorphanol; Male; Morphine; Noscapine; Rats; Rats, Inbred Strains; Receptors, Serotonin

1989
Narcotic usage in renal failure.
    The International journal of artificial organs, 1988, Volume: 11, Issue:6

    Topics: Analgesics, Opioid; Codeine; Humans; Kidney Failure, Chronic; Methadone; Morphine

1988
Opiate-induced rhabdomyolysis.
    Human toxicology, 1985, Volume: 4, Issue:1

    Topics: Acute Kidney Injury; Adult; Aspartate Aminotransferases; Codeine; Creatine Kinase; Creatinine; Cyclizine; Drug Combinations; Female; Humans; Hypocalcemia; Male; Methadone; Middle Aged; Morphine; Myoglobin; Narcotics; Phosphates; Rhabdomyolysis; Suicide, Attempted

1985
Experience with a haemagglutination inhibition test for morphine detection in urine.
    Annals of clinical biochemistry, 1985, Volume: 22 ( Pt 2)

    Topics: Chromatography, Thin Layer; Codeine; Hemagglutination Inhibition Tests; Humans; Morphine; Radioimmunoassay

1985
[Methodology and interpretation of morphiate detection in urine samples].
    Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1985, Volume: 95, Issue:2

    Topics: Codeine; Heroin Dependence; Humans; Kinetics; Morphine

1985
Improved method for the simultaneous determination of morphine, codeine and dihydrocodeine in blood by high-performance liquid chromatography with electrochemical detection.
    Journal of chromatography, 1985, Nov-22, Volume: 347, Issue:3

    Topics: Chromatography, High Pressure Liquid; Codeine; Electrochemistry; Glucuronidase; Humans; Hydrolysis; Indicators and Reagents; Morphine; Nitrates

1985
Metabolism of narcotics.
    British medical journal (Clinical research ed.), 1984, Jan-21, Volume: 288, Issue:6412

    Topics: Codeine; Humans; Kidney; Liver; Morphine

1984
Effect of pentazocine and related compounds on the lipid composition of Ehrlich ascites tumor cells.
    Japanese journal of pharmacology, 1982, Volume: 32, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cholesterol; Chromatography, Gas; Codeine; Fatty Acids; Female; Lipid Metabolism; Mice; Morphine; Neoplasms, Experimental; Pentazocine; Phospholipids; Triglycerides

1982
Simultaneous determination of dihydrocodeine and dihydromorphine in serum by gas chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Biomedical applications, 1995, Jan-06, Volume: 663, Issue:1

    Topics: Codeine; Dihydromorphine; Gas Chromatography-Mass Spectrometry; Humans; Morphine; Reproducibility of Results; Sensitivity and Specificity

1995
Drugs of abuse screening in the West Midlands: a 6 year retrospective survey of results.
    Annals of clinical biochemistry, 1994, Volume: 31 ( Pt 5)

    Topics: Amphetamine; Cannabinoids; Chromatography, Thin Layer; Cocaine; Codeine; Humans; Illicit Drugs; Longitudinal Studies; Methamphetamine; Morphine; Phenobarbital; Retrospective Studies; Substance-Related Disorders; United Kingdom

1994
Affinity profiles of morphine, codeine, dihydrocodeine and their glucuronides at opioid receptor subtypes.
    Life sciences, 1995, Volume: 56, Issue:10

    Topics: Animals; Benzeneacetamides; Binding, Competitive; Brain; Codeine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glucuronates; Guinea Pigs; Morphine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tritium

1995
[Two traffic accidents after heroin consumption with fatal outcome].
    Blutalkohol, 1994, Volume: 31, Issue:4

    Topics: Accidents, Traffic; Cause of Death; Cocaine; Codeine; Fatal Outcome; Heroin; Heroin Dependence; Humans; Morphine; Substance-Related Disorders

1994
Simultaneous determination of drugs of abuse (opiates, cocaine and amphetamine) in human hair by GC/MS and its application to a methadone treatment program.
    Forensic science international, 1993, Volume: 63, Issue:1-3

    Topics: Adult; Amphetamine; Calibration; Cocaine; Codeine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Illicit Drugs; Male; Methadone; Morphine; Morphine Derivatives; Reproducibility of Results; Substance Abuse Detection; Substance-Related Disorders

1993
Evaluation of a method for simultaneous quantification of codeine, dihydrocodeine, morphine, and 6-monoacetylmorphine in serum, blood, and postmortem blood.
    International journal of legal medicine, 1993, Volume: 106, Issue:2

    Topics: Codeine; Gas Chromatography-Mass Spectrometry; Humans; Morphine; Morphine Derivatives; Opioid-Related Disorders; Postmortem Changes

1993
Determination of dihydrocodeine in hair of opiate addicts by GC/MS.
    International journal of legal medicine, 1993, Volume: 105, Issue:5

    Topics: Codeine; Cross Reactions; Gas Chromatography-Mass Spectrometry; Hair; Heroin; Heroin Dependence; Humans; Morphine; Substance Abuse Detection

1993
Post-operative analgesia for craniotomy patients: current attitudes among neuroanaesthetists.
    European journal of anaesthesiology, 1995, Volume: 12, Issue:6

    Topics: Analgesia; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesiology; Attitude of Health Personnel; Codeine; Craniotomy; Humans; Hypnotics and Sedatives; Injections, Intramuscular; Intraoperative Care; Ireland; Morphine; Neurosurgery; Pain, Postoperative; Postoperative Care; Prejudice; Respiration; Surveys and Questionnaires; United Kingdom

1995
Stability of opiates in hair fibers after exposure to cosmetic treatment.
    Forensic science international, 1996, Aug-15, Volume: 81, Issue:2-3

    Topics: Bias; Codeine; Drug Stability; Forensic Medicine; Hair; Hair Preparations; Humans; Morphine; Narcotics; Reproducibility of Results; Substance Abuse Detection; Substance-Related Disorders

1996
[Changes in the pattern of opioid analgesic consumption in Spain].
    Medicina clinica, 1997, Sep-13, Volume: 109, Issue:8

    Topics: Administration, Oral; Administration, Rectal; Analgesics, Opioid; Buprenorphine; Codeine; Databases as Topic; Dextropropoxyphene; Drug Prescriptions; Humans; Injections, Intravenous; Linear Models; Meperidine; Methadone; Morphine; Pentazocine; Spain; Tilidine; Tramadol

1997
Distinction among eight opiate drugs in urine by gas chromatography-mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 1999, Volume: 20, Issue:5

    Topics: Codeine; Gas Chromatography-Mass Spectrometry; Humans; Hydrocodone; Hydromorphone; Molecular Structure; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Oxymorphone

1999
GCD quantitation of opiates as propionyl derivatives in blood.
    Journal of analytical toxicology, 2000, Volume: 24, Issue:2

    Topics: Anhydrides; Codeine; Ethylamines; Ethylmorphine; Gas Chromatography-Mass Spectrometry; Humans; Morphine; Morphine Derivatives; Narcotics; Propionates; Reproducibility of Results; Substance Abuse Detection

2000
Modified liquid junction interface for nonaqueous capillary electrophoresis-mass spectrometry.
    Electrophoresis, 2000, Volume: 21, Issue:15

    Topics: Codeine; Electrophoresis, Capillary; Equipment Design; Indicators and Reagents; Levorphanol; Methadone; Morphine; Pentazocine; Pharmaceutical Preparations; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2000
[Paliative treatment: Treatment of chronic cancer pain (ii): the use of opiates].
    Atencion primaria, 2002, May-15, Volume: 29, Issue:8

    Topics: Administration, Cutaneous; Administration, Oral; Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Codeine; Fentanyl; Humans; Morphine; Narcotics; Neoplasms; Pain; Palliative Care; Time Factors; Tramadol

2002
A rapid GC-MS method for the determination of dihydrocodeine, codeine, norcodeine, morphine, normorphine and 6-MAM in urine.
    Forensic science international, 2002, Jun-25, Volume: 127, Issue:1-2

    Topics: Adolescent; Adult; Codeine; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Morphine; Morphine Derivatives; Narcotics

2002
Dihydrocodeine; further development in measurement of analgesic power and appraisal of psychologic side effects of analgesic agents.
    The New England journal of medicine, 1956, May-10, Volume: 254, Issue:19

    Topics: Analgesics; Codeine; Humans; Morphine

1956
A comparison of the analgesic and respiratory effects of dihydrocodeine and morphine in man.
    Archives internationales de pharmacodynamie et de therapie, 1958, Sep-01, Volume: 116, Issue:3-4

    Topics: Analgesics; Cell Respiration; Codeine; Humans; Male; Morphine; Respiration

1958
[Comparison of morphine, pethidine & dihydrocodeine as postoperative analgesics].
    Nordisk medicin, 1959, Jun-04, Volume: 61, Issue:23

    Topics: Analgesia; Analgesics; Analgesics, Non-Narcotic; Anesthesia; Anesthesia and Analgesia; Antipyretics; Codeine; Meperidine; Morphine; Pain Management

1959
Synergetic action of 2(o-methoxyphenoxymethyl)-5-oxazolidone on morphine, dihydrocodeine and aminopyrine analgesia.
    Nature, 1960, Jun-11, Volume: 186

    Topics: Aminopyrine; Analgesia; Anesthesia; Anesthesia and Analgesia; Codeine; Humans; Morphine; Pain Management; Tranquilizing Agents

1960
Activation of G-proteins by morphine and codeine congeners: insights to the relevance of O- and N-demethylated metabolites at mu- and delta-opioid receptors.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:2

    Topics: Animals; CHO Cells; Codeine; Cricetinae; Female; GTP-Binding Proteins; Humans; Male; Morphine; Morphine Derivatives; Narcotics; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship

2004
Distribution of drugs of abuse within specific regions of the human brain.
    Forensic science international, 2007, Aug-06, Volume: 170, Issue:2-3

    Topics: Adolescent; Adult; Aged; Cerebellum; Cocaine; Codeine; Dopamine Uptake Inhibitors; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Medulla Oblongata; Middle Aged; Morphine; Narcotics; Substance Abuse Detection; Substance-Related Disorders; Tissue Distribution

2007
Inhibitory effects of opioids on compound action potentials in frog sciatic nerves and their chemical structures.
    Life sciences, 2008, Aug-01, Volume: 83, Issue:5-6

    Topics: Action Potentials; Analgesics, Opioid; Animals; Calcium Channels; Cocaine; Codeine; Ethylmorphine; Female; Male; Morphine; Naloxone; Potassium Channels, Voltage-Gated; Ranidae; Receptors, Opioid; Sciatic Nerve; Structure-Activity Relationship; Tetrodotoxin

2008
Structure studies in morphine; the degradation of dihydrocodeine to nitrogen free compounds.
    The Journal of organic chemistry, 1948, Volume: 13, Issue:5

    Topics: Codeine; Morphine; Nitrogen; Nitrogen Compounds; Organic Chemicals

1948
Quantitation of opioids in whole blood by electron impact-gas chromatography-mass spectrometry.
    Journal of analytical toxicology, 2011, Volume: 35, Issue:2

    Topics: Analgesics, Opioid; Codeine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Oxycodone; Oxymorphone; Substance Abuse Detection

2011
Comprehensive automation of the solid phase extraction gas chromatographic mass spectrometric analysis (SPE-GC/MS) of opioids, cocaine, and metabolites from serum and other matrices.
    Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:18

    Topics: Acetamides; Analgesics, Opioid; Automation; Cocaine; Codeine; Flunitrazepam; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Methadone; Morphine; Morphine Derivatives; Reproducibility of Results; Robotics; Solid Phase Extraction; Substance Abuse Detection; Trimethylsilyl Compounds

2014
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry

2014
Enantioselective synthesis of (-)-dihydrocodeine and formal synthesis of (-)-thebaine, (-)-codeine, and (-)-morphine from a deprotonated α-aminonitrile.
    Organic letters, 2014, Oct-17, Volume: 16, Issue:20

    Topics: Codeine; Hydrogenation; Molecular Structure; Morphine; Nitriles; Stereoisomerism; Thebaine

2014
Identification of opioids in surface and wastewaters by LC/QTOF-MS using retrospective data analysis.
    The Science of the total environment, 2019, May-10, Volume: 664

    Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Data Analysis; Environmental Monitoring; Fentanyl; Heroin; Hydrocodone; Hydromorphone; Minnesota; Morphine; Morphine Derivatives; Oxycodone; Retrospective Studies; Substance Abuse Detection; Tandem Mass Spectrometry; Tramadol; Wastewater; Water Pollutants, Chemical

2019