dihydrocodeine and dihydromorphine

dihydrocodeine has been researched along with dihydromorphine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (58.33)18.2507
2000's1 (8.33)29.6817
2010's3 (25.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Bellman, K; Knegtel, RM; Settimo, L1
Fromm, MF; Griese, EU; Hofmann, U; Mikus, G1
Fromm, MF; Hofmann, U; Johnson, S; Mikus, G1
Hufschmid, E; Theurillat, R; Thormann, W; Wilder-Smith, CH1
Kirkwood, LC; Nation, RL; Somogyi, AA1
Hufschmid, E; Thormann, W; Wilder-Smith, CH1
Aderjan, R; Klinder, K; Lutz, R; Mattern, R; Pötsch, L; Skopp, G; Zimmer, G1
Aderjan, R; Klinder, K; Mattern, R; Skopp, G1
Abdul-Manap, R; Hofmann, U; Kamali, F; Mikus, G; Rostami-Hodjegan, A; Webb, JA1
Kamińska, E; Leppert, W; Mikołajczak, P; Szulc, M1
Yamazaki, H1
Cai, H; Chen, M; He, B; Huang, J; Huang, X; Tan, Z; Zhang, B; Zhu, Z1

Reviews

1 review(s) available for dihydrocodeine and dihydromorphine

ArticleYear
[Message from the President of the Japanese Society for the Study of Xenobiotics].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019, Volume: 139, Issue:3

    Topics: Child; Child, Preschool; Codeine; Cytochrome P-450 CYP2D6; Dihydromorphine; Drug Discovery; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Humans; Infant; Japan; Societies, Scientific; Translational Research, Biomedical; Xenobiotics

2019

Trials

4 trial(s) available for dihydrocodeine and dihydromorphine

ArticleYear
Dihydrocodeine: a new opioid substrate for the polymorphic CYP2D6 in humans.
    Clinical pharmacology and therapeutics, 1995, Volume: 58, Issue:4

    Topics: Adult; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Dihydromorphine; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Metabolic Clearance Rate; Mixed Function Oxygenases; Phenotype; Sparteine

1995
The visceral and somatic antinociceptive effects of dihydrocodeine and its metabolite, dihydromorphine. A cross-over study with extensive and quinidine-induced poor metabolizers.
    British journal of clinical pharmacology, 1998, Volume: 45, Issue:6

    Topics: Adult; Analgesics, Opioid; Codeine; Cross-Over Studies; Dihydromorphine; Double-Blind Method; Electric Stimulation; Humans; Male; Pain Measurement; Pain Threshold; Quinidine; Skin Physiological Phenomena

1998
Contribution of dihydrocodeine and dihydromorphine to analgesia following dihydrocodeine administration in man: a PK-PD modelling analysis.
    British journal of clinical pharmacology, 2001, Volume: 52, Issue:1

    Topics: Administration, Oral; Adult; Analgesia; Analgesics, Opioid; Area Under Curve; Codeine; Cross-Over Studies; Dihydromorphine; Double-Blind Method; Female; Humans; Male; Models, Biological; Pain; Pain Measurement; Pain Threshold; Skin Physiological Phenomena

2001
Analgesia and serum assays of controlled-release dihydrocodeine and metabolites in cancer patients with pain.
    Pharmacological reports : PR, 2012, Volume: 64, Issue:1

    Topics: Aged; Aged, 80 and over; Analgesia; Analgesics, Opioid; Codeine; Dihydromorphine; Female; Humans; Male; Middle Aged; Neoplasms; Nociceptive Pain; Pain Management; Pain Measurement

2012

Other Studies

7 other study(ies) available for dihydrocodeine and dihydromorphine

ArticleYear
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Simultaneous determination of dihydrocodeine and dihydromorphine in serum by gas chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Biomedical applications, 1995, Jan-06, Volume: 663, Issue:1

    Topics: Codeine; Dihydromorphine; Gas Chromatography-Mass Spectrometry; Humans; Morphine; Reproducibility of Results; Sensitivity and Specificity

1995
Characterization of the genetic polymorphism of dihydrocodeine O-demethylation in man via analysis of urinary dihydrocodeine and dihydromorphine by micellar electrokinetic capillary chromatography.
    Journal of chromatography. B, Biomedical applications, 1996, Mar-29, Volume: 678, Issue:1

    Topics: Codeine; Dihydromorphine; Electrophoresis, Capillary; Humans; Methylation; Micelles; Phenotype; Polymorphism, Genetic; Quinidine; Reference Values

1996
Determination of the dihydrocodeine metabolites, dihydromorphine and nordihydrocodeine, in hepatic microsomal incubations by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Nov-07, Volume: 701, Issue:1

    Topics: Analgesics, Opioid; Animals; Antitussive Agents; Chromatography, High Pressure Liquid; Codeine; Cytochrome P-450 CYP2D6; Dihydromorphine; Humans; In Vitro Techniques; Microsomes, Liver; Oxidation-Reduction; Rats; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

1997
Postmortem distribution of dihydrocodeine and metabolites in a fatal case of dihydrocodeine intoxication.
    Forensic science international, 1998, Jul-20, Volume: 95, Issue:2

    Topics: Adult; Analgesics, Opioid; Blood Chemical Analysis; Brain Chemistry; Chromatography, High Pressure Liquid; Codeine; Dihydromorphine; Fatal Outcome; Gas Chromatography-Mass Spectrometry; Hair; Humans; Kidney; Liver; Male; Morphine Derivatives; Postmortem Changes

1998
The detection of dihydrocodeine and its main metabolites in cases of fatal overdose.
    International journal of legal medicine, 1999, Volume: 112, Issue:3

    Topics: Adult; Analgesics, Opioid; Chromatography, High Pressure Liquid; Codeine; Dihydromorphine; Drug Overdose; Forensic Medicine; Humans; Male; Poisoning

1999
Development of a Sensitive and Rapid HPLC-MS Method for Dihydrocodeine and Dihydromorphine: Application to Bioequivalence Studies.
    Journal of chromatographic science, 2022, Dec-13, Volume: 60, Issue:10

    Topics: Chromatography, High Pressure Liquid; Dihydromorphine; Humans; Reproducibility of Results; Tandem Mass Spectrometry; Therapeutic Equivalency

2022