Page last updated: 2024-09-04

dihydrobunolol and levobunolol

dihydrobunolol has been researched along with levobunolol in 9 studies

Compound Research Comparison

Studies
(dihydrobunolol)
Trials
(dihydrobunolol)
Recent Studies (post-2010)
(dihydrobunolol)
Studies
(levobunolol)
Trials
(levobunolol)
Recent Studies (post-2010) (levobunolol)
9012527712

Protein Interaction Comparison

ProteinTaxonomydihydrobunolol (IC50)levobunolol (IC50)
Beta-2 adrenergic receptorHomo sapiens (human)0.0008
Beta-1 adrenergic receptorHomo sapiens (human)0.0069
Beta-3 adrenergic receptorHomo sapiens (human)0.34
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)2.901
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)2.901
Sodium-dependent serotonin transporterHomo sapiens (human)4.898
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.773

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's3 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Di Carlo, FJ; Leinweber, FJ; Szpiech, JM1
McGhee, CN; Midgley, JM; Watson, DG1
Ashton, P; Lee, VH; Wang, W1
Nieves, AL; Novack, GD; Potter, DE; Williams, LS; Woodward, DF1
Richman, JB; Shackleton, M; Tang-Liu, DD1
Liu, S; Neff, J; Sandri, R; Tang-Liu, DD1
Hengy, H; Kölle, EU1
Acheampong, AA; Breau, A; Lam, S; Luo, W; Shackleton, M; Tang-Liu, DD1
Argikar, UA; Cirello, AL; Dumouchel, JL; Dunne, CE; Gunduz, M; Saran, C1

Other Studies

9 other study(ies) available for dihydrobunolol and levobunolol

ArticleYear
l-bunolol metabolites in human urine.
    Pharmacology, 1978, Volume: 16, Issue:2

    Topics: Acetates; Administration, Oral; Adult; Biotransformation; Chemical Fractionation; Chromatography, Thin Layer; Glucuronates; Humans; Lactates; Levobunolol; Male; Sulfates

1978
Determination of (-)-bunolol and its metabolite, dihydro-(-)-bunolol, in human aqueous humour by gas chromatography-negative ion chemical ionisation mass spectrometry.
    Journal of chromatography, 1991, Nov-15, Volume: 571, Issue:1-2

    Topics: Aqueous Humor; Gas Chromatography-Mass Spectrometry; Humans; Levobunolol

1991
Location of penetration and metabolic barriers to levobunolol in the corneal epithelium of the pigmented rabbit.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2

    Topics: Animals; Benzalkonium Compounds; Cornea; Edetic Acid; Epithelium; Levobunolol; Male; Pigment Epithelium of Eye; Rabbits; Time Factors

1991
Dihydrolevobunolol is a potent ocular beta-adrenoceptor antagonist.
    Journal of ocular pharmacology, 1987,Spring, Volume: 3, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Chemical Phenomena; Chemistry; Eye; Female; Intraocular Pressure; Isoproterenol; Levobunolol; Male; Rabbits

1987
Ocular metabolism of levobunolol.
    Journal of ocular pharmacology, 1988,Fall, Volume: 4, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Eye; Levobunolol; Rabbits; Stereoisomerism; Tissue Distribution

1988
Disposition of levobunolol after an ophthalmic dose to rabbits.
    Journal of pharmaceutical sciences, 1987, Volume: 76, Issue:10

    Topics: Animals; Aqueous Humor; Eye; Female; Levobunolol; Ophthalmic Solutions; Rabbits; Tissue Distribution

1987
Determination of levobunolol and dihydrolevobunolol in blood and urine by high-performance liquid chromatography using fluorescence detection.
    Journal of chromatography, 1985, Mar-22, Volume: 338, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Humans; Levobunolol; Metoprolol; Spectrometry, Fluorescence; Stereoisomerism; Time Factors

1985
Comparison of concentration-time profiles of levobunolol and timolol in anterior and posterior ocular tissues of albino rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1995,Winter, Volume: 11, Issue:4

    Topics: Absorption; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Biological Availability; Choroid; Ciliary Body; Eye; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Iris; Levobunolol; Ophthalmic Solutions; Optic Nerve; Rabbits; Retina; Timolol; Tissue Distribution; Vitreous Body

1995
Ocular Metabolism of Levobunolol: Historic and Emerging Metabolic Pathways.
    Drug metabolism and disposition: the biological fate of chemicals, 2016, Volume: 44, Issue:8

    Topics: Acetylation; Adrenergic beta-Antagonists; Animals; Biotransformation; Eye; Humans; Kinetics; Levobunolol; Liver; Male; Molecular Structure; Organ Specificity; Rabbits; Rats, Sprague-Dawley

2016