digoxin and lornoxicam

digoxin has been researched along with lornoxicam* in 1 studies

Reviews

1 review(s) available for digoxin and lornoxicam

ArticleYear
Clinical pharmacological studies of some possible interactions of lornoxicam with other drugs.
    Postgraduate medical journal, 1990, Volume: 66 Suppl 4

    A series of studies in human subjects of potential interactions of lornoxicam with some other drugs is reviewed. No evidence of kinetic interaction was found with the antacids Maalox or Solugastrol, nor was there evidence of influence on antipyrine clearance. Lornoxicam reduced warfarin clearance and enhanced its hypoprothrombinaemic effect. It did not influence glibenclamide kinetics, but plasma insulin concentrations were significantly higher and plasma glucose concentrations significantly lower when lornoxicam and glibenclamide were co-administered. Lornoxicam produced a modest reduction in digoxin clearance, but no other clear evidence of interaction was seen. Lornoxicam significantly antagonized the diuretic and natriuretic actions of frusemide.

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Digoxin; Drug Interactions; Furosemide; Glyburide; Humans; Male; Piroxicam; Warfarin

1990