Page last updated: 2024-08-21

digoxigenin and digitoxigenin

digoxigenin has been researched along with digitoxigenin in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199019 (70.37)18.7374
1990's4 (14.81)18.2507
2000's3 (11.11)29.6817
2010's1 (3.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ball, WJ; Farr, CD; Fishwild, DM; Nair, AC; Tabet, MR; Wang, X; Welsh, WJ1
Korndörfer, IP; Schlehuber, S; Skerra, A1
Austin, CA; Ayuso, MJ; Azrak, SS; Cortés, F; López-Lázaro, M; Pastor, N1
Yoda, A; Yoda, S1
Bossaller, C; Schmoldt, A1
Lenstra, JB; Meilink, JW; Svendsen, AB1
Flasch, H; Heinz, N; Petersen, R1
Budzikiewicz, H; Flaskamp, E1
Cano, JP; de Sousa, G; Durand, A; Lacarelle, B; Placidi, M; Rahmani, R1
Johannes, A; Schmoldt, A; von Meyerinck, L1
Bhandary, KK; Go, KT1
Ahmed, K; Deffo, T; From, AH; Fullerton, DS; Kitatsuji, E; Rohrer, DC1
Pribyl, T; Schreiber, V; Stárka, L; Stĕpán, J1
LeWinn, EB1
Frey, WA; Vallee, BL1
Kanai, S; Kitani, K; Nokubo, M; Sato, Y1
Kitani, K; Sato, Y; van Bezooijen, K1
Dessi, JL; Self, CH; Winger, LA1
Adamczyk, M; Grote, J1
RAND, M; STAFFORD, A1
BROWN, BT; STAFFORD, A; WRIGHT, SE1
FOERSTER, W; STOLZENBURG, U1
BLANKENHORN, DH; JELLIFFE, RW1
KRONEBERG, G1
REPKE, K1
ELDERFIELD, RC; FRIED, J; UHLE, FC1
Kataoka, T; Okina, Y; Takada, Y; Takeuchi, F; Yokomichi, T1

Reviews

1 review(s) available for digoxigenin and digitoxigenin

ArticleYear
The steroidal actions of digitalis.
    Perspectives in biology and medicine, 1984,Winter, Volume: 27, Issue:2

    Topics: Animals; Cardiotonic Agents; Digitalis; Digitoxigenin; Digoxigenin; Estradiol; Estrogens; Female; Gonadal Steroid Hormones; Humans; Male; Plants, Medicinal; Plants, Toxic; Spironolactone; Steroids; Structure-Activity Relationship

1984

Other Studies

26 other study(ies) available for digoxigenin and digitoxigenin

ArticleYear
Three-dimensional quantitative structure-activity relationship analysis of ligand binding to human sequence antidigoxin monoclonal antibodies using comparative molecular field analysis.
    Journal of medicinal chemistry, 2002, Jul-18, Volume: 45, Issue:15

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Binding Sites, Antibody; Binding, Competitive; Carbohydrate Sequence; Digoxin; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin Fab Fragments; Mice; Mice, Transgenic; Models, Molecular; Molecular Sequence Data; Ouabain; Progesterone; Quantitative Structure-Activity Relationship; Radioligand Assay

2002
Structural mechanism of specific ligand recognition by a lipocalin tailored for the complexation of digoxigenin.
    Journal of molecular biology, 2003, Jul-04, Volume: 330, Issue:2

    Topics: Animals; Binding Sites; Carrier Proteins; Crystallography, X-Ray; Digitoxigenin; Digoxigenin; In Vitro Techniques; Lepidoptera; Ligands; Models, Molecular; Molecular Structure; Protein Conformation; Protein Engineering

2003
Digitoxin inhibits the growth of cancer cell lines at concentrations commonly found in cardiac patients.
    Journal of natural products, 2005, Volume: 68, Issue:11

    Topics: Antineoplastic Agents; Cardiotonic Agents; Digitoxin; DNA Damage; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Molecular Structure; Tumor Cells, Cultured

2005
Association and dissociation rate constants of the complexes between various cardiac aglycones and sodium- and potassium-dependent adenosine triphosphatase formed in the presence of magnesium and phosphate.
    Molecular pharmacology, 1977, Volume: 13, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Brain; Cardenolides; Cattle; Chemical Phenomena; Chemistry; Digitoxigenin; Digoxigenin; In Vitro Techniques; Kinetics; Magnesium; Microsomes; Ouabain; Phosphates; Potassium; Proteins; Sodium; Strophanthidin; Time Factors

1977
Dehydro-digitoxosides of digitoxigenin and digoxigenin: binding to beef heart (Na+ + K+)-ATPase in relation to unchanged digitoxosides.
    Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 306, Issue:1

    Topics: Animals; Biotransformation; Cattle; Digitoxigenin; Digoxigenin; Digoxin; In Vitro Techniques; Kinetics; Myocardium; Ouabain; Sodium-Potassium-Exchanging ATPase; Time Factors

1979
Gas-liquid chromatography of digitoxigenin and digoxigenin as acetates of their epoxygeninic acid methyl esters.
    Journal of chromatography, 1979, Feb-11, Volume: 170, Issue:1

    Topics: Acetates; Chromatography, Gas; Digitoxigenin; Digoxigenin; Digoxin; Drug Stability; Epoxy Compounds; Esters

1979
[Synthesis and characterization of some cardenolide glucuronides and sulphates (author's transl)].
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:3

    Topics: Animals; Cardenolides; Cats; Digitoxigenin; Digitoxin; Digoxigenin; Digoxin; Glucuronates; Guinea Pigs; Heart; In Vitro Techniques; Magnetic Resonance Spectroscopy; Solubility; Structure-Activity Relationship; Sulfates

1977
Ring-D fragmentation of cardenolides.
    Biomedical mass spectrometry, 1977, Volume: 4, Issue:6

    Topics: Cardenolides; Deuterium; Digitoxigenin; Digoxigenin; Mass Spectrometry; Oxygen Isotopes

1977
Metabolism of digoxin, digoxigenin digitoxosides and digoxigenin in human hepatocytes and liver microsomes.
    Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:7

    Topics: Biotransformation; Cells, Cultured; Chromatography, High Pressure Liquid; Digitoxigenin; Digoxigenin; Digoxin; Glucuronosyltransferase; Humans; In Vitro Techniques; Liver; Microsomes, Liver

1991
Purification of a rat liver cytosolic sulfotransferase responsible for the conjugation of digitoxigenin.
    Biochemical pharmacology, 1990, Jan-15, Volume: 39, Issue:2

    Topics: Animals; Chromatography, Ion Exchange; Cytosol; Digitoxigenin; Digitoxin; Digoxigenin; Electrophoresis, Polyacrylamide Gel; Female; Kinetics; Liver; Rats; Rats, Inbred Strains; Sulfotransferases; Sulfurtransferases

1990
Structural studies on the biosides of Digitalis lanata: bisdigitoxosides of digitoxigenin, gitoxigenin and digoxigenin.
    Acta crystallographica. Section B, Structural science, 1989, Jun-01, Volume: 45 ( Pt 3)

    Topics: Cardenolides; Cardiac Glycosides; Digitalis; Digitoxigenin; Digoxigenin; Molecular Conformation; Molecular Structure; Plants, Medicinal; Plants, Toxic; Structure-Activity Relationship; X-Ray Diffraction

1989
The inotropic activity of digitalis genins is dependent upon C(17) side-group carbonyl oxygen position.
    Journal of molecular and cellular cardiology, 1984, Volume: 16, Issue:9

    Topics: Animals; Cardiotonic Agents; Cats; Digitoxigenin; Digoxigenin; Digoxin; Dose-Response Relationship, Drug; Myocardial Contraction; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship; X-Ray Diffraction

1984
[Biological and immunological activity similar to digitalis glycosides of synthetic ACTH and some sex hormone 14-hydroxyderivatives (author's transl)].
    Casopis lekaru ceskych, 1981, May-21, Volume: 120, Issue:20

    Topics: Adrenocorticotropic Hormone; Antigens; Digitoxigenin; Digoxigenin; Digoxin; Erythrocytes; Estradiol; Estrone; Hormones; Humans; Hydroxyestrones; Hydroxytestosterones; Immunoenzyme Techniques; Radioisotopes; Rubidium; Testosterone

1981
Digitalis metabolism and human liver alcohol dehydrogenase.
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:2

    Topics: Alcohol Oxidoreductases; Chelating Agents; Digitalis Glycosides; Digitoxigenin; Digoxigenin; Humans; Isoenzymes; Kinetics; Liver; Substrate Specificity

1980
Biliary excretion of digitoxin and its metabolites in young and old male Wistar rats.
    Experimental gerontology, 1982, Volume: 17, Issue:6

    Topics: Aging; Animals; Bile; Digitoxigenin; Digitoxin; Digoxigenin; Injections, Intravenous; Kidney; Liver; Male; Myocardium; Rats; Rats, Inbred Strains

1982
The effect of age on the biliary excretion of digitoxin and its metabolites in female BN/Bi rats.
    Archives of gerontology and geriatrics, 1982, Volume: 1, Issue:1

    Topics: Aging; Animals; Bile; Digitoxigenin; Digitoxin; Digoxigenin; Female; Rats; Rats, Inbred BN

1982
Ultra-specific immunoassays for small molecules: roles of wash steps and multiple binding formats.
    Clinical chemistry, 1996, Volume: 42, Issue:9

    Topics: Antibodies, Monoclonal; Digitoxigenin; Digitoxin; Digoxigenin; Digoxin; Immunoassay; Sensitivity and Specificity; Strophanthidin

1996
Efficient synthesis of 3-aminodigoxigenin and 3-aminodigitoxigenin probes.
    Bioorganic & medicinal chemistry letters, 1999, Mar-08, Volume: 9, Issue:5

    Topics: Cardiotonic Agents; Chromatography, High Pressure Liquid; Digitalis; Digitoxigenin; Digoxigenin; Immunoassay; Plants, Medicinal; Plants, Toxic

1999
The duration of action of some cardiac glycosides and aglycones in the guinea-pig.
    British journal of pharmacology and chemotherapy, 1959, Volume: 14, Issue:2

    Topics: Biological Transport; Cardiac Glycosides; Digitalis Glycosides; Digitoxigenin; Digitoxin; Digoxigenin; Digoxin; Guinea Pigs; Heart; Humans; Lanatosides; Ouabain

1959
Chemical structure and pharmacological activity of some derivatives of digitoxigenin and digoxigenin.
    British journal of pharmacology and chemotherapy, 1962, Volume: 18

    Topics: Animals; Cardiac Glycosides; Cats; Digitalis; Digitalis Glycosides; Digitoxigenin; Digoxigenin; Guinea Pigs; Heart; Myocardial Contraction; Papillary Muscles

1962
[ON THE STRUCTURE-EFFECT RELATION OF CARDENOLIDES AND BUFADIENOLIDES. III. EFFECT OF RESERPINE PRETREATMENT ON THE EFFECT OF DIGITOXIGENIN AND DIGOXIGENIN ON THE HEART].
    Acta biologica et medica Germanica, 1963, Volume: 11

    Topics: Animals; Bufanolides; Cardenolides; Digitalis Glycosides; Digitoxigenin; Digoxigenin; Guinea Pigs; Heart; Research; Reserpine

1963
GAS CHROMATOGRAPHY OF DIGITOXIGENIN AND DIGOXIGENIN.
    Journal of chromatography, 1963, Volume: 12

    Topics: Chromatography; Chromatography, Gas; Digitalis Glycosides; Digitoxigenin; Digitoxin; Digoxigenin; Digoxin

1963
[Sugar content and the action of digitoxigenin- and digoxigenin digitoxosides].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1959, Volume: 237

    Topics: Digitalis; Digitalis Glycosides; Digitoxigenin; Digoxigenin; Plant Extracts

1959
[The bis- and mono-digitoxosides of digitoxigenin and digoxigenin: metabolites of digitoxin].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1959, Volume: 237

    Topics: Digitalis; Digitalis Glycosides; Digitoxigenin; Digitoxin; Digoxigenin; Humans; Plant Extracts

1959
Synthesis of glucosides of digitoxigenin, digoxigenin and periplogenin.
    Journal of the American Chemical Society, 1947, Volume: 69, Issue:9

    Topics: Digitoxigenin; Digoxigenin; Glucosides

1947
Cardenolide aglycones inhibit tumor necrosis factor α-induced expression of intercellular adhesion molecule-1 at the translation step by blocking Na⁺/K⁺-ATPase.
    Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:1

    Topics: Animals; Cell Line; Cell Line, Tumor; Cell Survival; Digitoxigenin; Digoxigenin; Humans; Intercellular Adhesion Molecule-1; Ouabain; Protein Biosynthesis; Rats; RNA, Messenger; RNA, Small Interfering; Sodium-Potassium-Exchanging ATPase; Tumor Necrosis Factor-alpha

2015