diglycolic acid has been researched along with diethylene glycol in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 5 (55.56) | 2.80 |
| Authors | Studies |
|---|---|
| Landry, GM; Martin, S; McMartin, KE | 1 |
| Bartels, MJ; Flanders, WD; Hunt, DR; Lewis, LS; McGeehin, MA; McMartin, KE; Perala, A; Schier, JG | 1 |
| Abreo, F; Dunning, CL; Landry, GM; Latimer, B; McMartin, KE; Orchard, E | 1 |
| Aw, TY; Conrad, T; Landry, GM; McMartin, KE; Nichols, R | 1 |
| Bordoni, LS; Costa, LM; Goulart, COL; Nascentes, CC | 1 |
| Freeman, DT; Landry, GM; Reed, KJ | 1 |
| Dwyer, D; Landry, GM; Luttrell-Williams, ES; McMartin, KE; Robinson, CN; Tobin, JD | 1 |
| Jamison, CN; McMartin, KE; Robinson, CN; Tobin, JD | 1 |
| Landry, GM; Luttrell-Williams, ES; McMartin, KE; Robinson, CN; Tobin, JD | 1 |
9 other study(ies) available for diglycolic acid and diethylene glycol
| Article | Year |
|---|---|
Diglycolic acid is the nephrotoxic metabolite in diethylene glycol poisoning inducing necrosis in human proximal tubule cells in vitro.
Topics: Acetates; Adenosine Triphosphate; Apoptosis; Cell Culture Techniques; Cells, Cultured; Dose-Response Relationship, Drug; Ethylene Glycols; Glycolates; Humans; Kidney Tubules, Proximal; Necrosis; Succinate Dehydrogenase | 2011 |
Characterizing concentrations of diethylene glycol and suspected metabolites in human serum, urine, and cerebrospinal fluid samples from the Panama DEG mass poisoning.
Topics: Acetates; Biomarkers; Case-Control Studies; Centers for Disease Control and Prevention, U.S.; Ethylene Glycols; Female; Fomepizole; Gas Chromatography-Mass Spectrometry; Glycolates; Humans; Kidney; Logistic Models; Male; Neurotoxicity Syndromes; Panama; Poisoning; Pyrazoles; Renal Dialysis; Specimen Handling; United States | 2013 |
Diethylene glycol-induced toxicities show marked threshold dose response in rats.
Topics: Acidosis; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Creatine; Dose-Response Relationship, Drug; Ethylene Glycols; Glycogen; Glycolates; Kidney; Kidney Diseases; Liver; Male; Rats, Inbred F344; Rats, Wistar | 2015 |
Diglycolic acid, the toxic metabolite of diethylene glycol, chelates calcium and produces renal mitochondrial dysfunction in vitro.
Topics: Acute Kidney Injury; Animals; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Ethylene Glycols; Glutamic Acid; Glycolates; Humans; Kidney; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Malates; Male; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Phosphorylation; Rats; Rats, Wistar | 2016 |
Analysis of Diglycolic Acid after Mass Poisoning by Diethylene Glycol.
Topics: Ethylene Glycols; Glycolates; Humans; Kidney | 2022 |
Diethylene glycol and its metabolites induce cell death in SH-SY5Y neuronal cells in vitro.
Topics: Acetates; Cell Death; Cell Line, Tumor; Ethylene Glycols; Glycolates; Humans; Neurons | 2021 |
Role of Plasma Membrane Dicarboxylate Transporters in the Uptake and Toxicity of Diglycolic Acid, a Metabolite of Diethylene Glycol, in Human Proximal Tubule Cells.
Topics: Animals; Cell Membrane; Dicarboxylic Acid Transporters; Humans; Kidney Tubules, Proximal; Organic Anion Transporters, Sodium-Dependent; Rats; Sodium; Succinates; Succinic Acid; Symporters | 2022 |
Variable sensitivity to diethylene glycol poisoning is related to differences in the uptake transporter for the toxic metabolite diglycolic acid.
Topics: Acute Kidney Injury; Animals; Dicarboxylic Acid Transporters; Ethylene Glycols; Humans; Kidney; Rats; Rats, Wistar | 2023 |
Lack of efflux of diglycolic acid from proximal tubule cells leads to its accumulation and to toxicity of diethylene glycol.
Topics: Animals; Glycolates; Humans; Kidney Tubules, Proximal; Organic Anion Transporters, Sodium-Independent; Rats; Succinates; Succinic Acid | 2023 |