digitoxin has been researched along with allose* in 1 studies
1 other study(ies) available for digitoxin and allose
| Article | Year |
|---|---|
De novo approach to 2-deoxy-beta-glycosides: asymmetric syntheses of digoxose and digitoxin.
A highly enantioselective and straightforward route to trisaccharide natural products digoxose and digitoxin has been developed. Key to this approach is the iterative application of the palladium-catalyzed glycosylation reaction, reductive 1,3-transposition, diastereoselective dihydroxylation, and regioselective protection. The first total synthesis of natural product digoxose was accomplished in 19 total steps from achiral 2-acylfuran, and digitoxin was fashioned in 15 steps starting from digitoxigenin 2 and pyranone 8beta. This flexible synthetic strategy also allows for the preparation of mono- and disaccharide analogues of digoxose and digitoxin. Topics: Carbohydrate Conformation; Catalysis; Digitoxin; Disaccharides; Glucose; Glycosylation; Oxygen; Palladium; Stereoisomerism; Trisaccharides | 2007 |