digitonin and honokiol

digitonin has been researched along with honokiol* in 1 studies

Other Studies

1 other study(ies) available for digitonin and honokiol

Article	Year
Multiple effects of honokiol on catecholamine secretion from adrenal chromaffin cells. Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1989, Volume: 13, Issue:4 The molecular mechanism of honokiol, extracted from the bark of Magnolia obovata, was studied using bovine adrenal chromaffin cells as a model system. Honokiol inhibits catecholamine secretion induced by carbachol and DMPP and that induced by exposure to high K+ and Ba2+ but to a lesser extent. The inhibitory effects of trifluoperazine and honokiol on carbachol-, high K(+)- and Ba2(+)- induced secretion were not additive. The results suggest that honokiol interferes with the interaction between the acetylcholine receptor and its agonists and that honokiol may also affect the steps in exocytosis after intracellular calcium has been raised, possibly at the site(s) where calmodulin acts. Topics: Adrenal Medulla; Animals; Barium; Biphenyl Compounds; Calcium; Carbachol; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Digitonin; Dimethylphenylpiperazinium Iodide; Exocytosis; Lignans; Potassium; Receptors, Cholinergic; Trifluoperazine	1989

Article

Year

Multiple effects of honokiol on catecholamine secretion from adrenal chromaffin cells.

Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1989, Volume: 13, Issue:4

The molecular mechanism of honokiol, extracted from the bark of Magnolia obovata, was studied using bovine adrenal chromaffin cells as a model system. Honokiol inhibits catecholamine secretion induced by carbachol and DMPP and that induced by exposure to high K+ and Ba2+ but to a lesser extent. The inhibitory effects of trifluoperazine and honokiol on carbachol-, high K(+)- and Ba2(+)- induced secretion were not additive. The results suggest that honokiol interferes with the interaction between the acetylcholine receptor and its agonists and that honokiol may also affect the steps in exocytosis after intracellular calcium has been raised, possibly at the site(s) where calmodulin acts.

Topics: Adrenal Medulla; Animals; Barium; Biphenyl Compounds; Calcium; Carbachol; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Digitonin; Dimethylphenylpiperazinium Iodide; Exocytosis; Lignans; Potassium; Receptors, Cholinergic; Trifluoperazine

1989