diflunisal glucuronide ester has been researched along with diflunisal in 11 studies
*Diflunisal: A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN. [MeSH]
*Diflunisal: A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN. [MeSH]
| Studies (diflunisal glucuronide ester) | Trials (diflunisal glucuronide ester) | Recent Studies (post-2010) (diflunisal glucuronide ester) | Studies (diflunisal) | Trials (diflunisal) | Recent Studies (post-2010) (diflunisal) |
|---|---|---|---|---|---|
| 11 | 0 | 0 | 605 | 129 | 145 |
| Protein | Taxonomy | diflunisal glucuronide ester (IC50) | diflunisal (IC50) |
|---|---|---|---|
| Carbonic anhydrase 1 | Homo sapiens (human) | 3.38 | |
| Carbonic anhydrase 2 | Homo sapiens (human) | 2.7 | |
| Transthyretin | Homo sapiens (human) | 5.4667 | |
| Solute carrier family 22 member 6 | Homo sapiens (human) | 0.85 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 8 (72.73) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dickinson, RG; King, AR | 4 |
| Dickinson, RG; King, AR; Pond, SM; Restifo, AC; Verbeeck, RK | 1 |
| Dickinson, RG; Watt, JA | 1 |
| Lin, JH; Lyon, KA; Musson, DG; Tocco, DJ; Yeh, KC | 1 |
| Meffin, PJ; Veenendaal, JR | 1 |
| De Jersey, J; Dickinson, RG; Williams, AM; Worrall, S | 1 |
| Dickinson, RG; Williams, AM | 1 |
| Dickinson, RG; Wang, M | 1 |
11 other study(ies) available for diflunisal glucuronide ester and diflunisal
| Article | Year |
|---|---|
Studies on the reactivity of acyl glucuronides--I. Phenolic glucuronidation of isomers of diflunisal acyl glucuronide in the rat.
Topics: Animals; Bile; Chromatography, High Pressure Liquid; Diflunisal; Glucuronates; Glucuronidase; Hydrogen-Ion Concentration; Isomerism; Male; Rats; Rats, Inbred Strains | 1991 |
Studies on the reactivity of acyl glucuronides--II. Interaction of diflunisal acyl glucuronide and its isomers with human serum albumin in vitro.
Topics: Diflunisal; Glucuronates; Half-Life; Humans; In Vitro Techniques; Isomerism; Serum Albumin | 1991 |
Diflunisal and its conjugates in patients with renal failure.
Topics: Adult; Diflunisal; Female; Half-Life; Humans; Kidney Failure, Chronic; Male; Middle Aged | 1991 |
Reactivity of diflunisal acyl glucuronide in human and rat plasma and albumin solutions.
Topics: Adult; Animals; Blood Proteins; Diflunisal; Female; Humans; Hydrolysis; Isomerism; Kidney Failure, Chronic; Male; Middle Aged; Plasma; Protein Binding; Rats; Rats, Inbred Strains; Serum Albumin; Solutions | 1990 |
Assay methodology for quantification of the ester and ether glucuronide conjugates of diflunisal in human urine.
Topics: Chromatography, High Pressure Liquid; Diflunisal; Drug Stability; Humans; Hydrogen-Ion Concentration; Salicylates; Solvents; Spectrophotometry, Ultraviolet | 1985 |
Direct analysis of diflunisal ester and ether glucuronides by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Diflunisal; Glucuronidase; Humans; Salicylates; Sodium Hydroxide | 1984 |
Studies on the reactivity of acyl glucuronides--VIII. Generation of an antiserum for the detection of diflunisal-modified proteins in diflunisal-dosed rats.
Topics: Animals; Cross Reactions; Diflunisal; Immune Sera; Liver; Molecular Weight; Proteins; Rats; Subcellular Fractions | 1995 |
Studies on the reactivity of acyl glucuronides--VI. Modulation of reversible and covalent interaction of diflunisal acyl glucuronide and its isomers with human plasma protein in vitro.
Topics: Diflunisal; Glucuronates; Humans; Hydrogen-Ion Concentration; Isomerism; Kinetics; Serum Albumin | 1994 |
Studies on the reactivity of acyl glucuronides--V. Glucuronide-derived covalent binding of diflunisal to bladder tissue of rats and its modulation by urinary pH and beta-glucuronidase.
Topics: Animals; Diflunisal; Glucuronates; Glucuronidase; Hydrogen-Ion Concentration; Rats; Time Factors; Urinary Bladder | 1993 |
Disposition and covalent binding of diflunisal and diflunisal acyl glucuronide in the isolated perfused rat liver.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diflunisal; Glucuronates; Inactivation, Metabolic; Liver; Male; Molecular Structure; Perfusion; Proteins; Rats; Sulfates | 1998 |
Rearrangement of diflunisal acyl glucuronide into its beta-glucuronidase-resistant isomers facilitates transport through the small intestine to the colon of the rat.
Topics: Animals; Animals, Outbred Strains; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Biological Transport; Colon; Diflunisal; Glucuronidase; Intestinal Absorption; Intestine, Small; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2001 |