Compounds > diflunisal

diflunisal and tolcapone

diflunisal has been researched along with tolcapone in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (20.00)	29.6817
2010's	5 (50.00)	24.3611
2020's	3 (30.00)	2.80

Authors

Authors	Studies
Chang, TK; Ensom, MH; Kiang, TK	1
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Albusairi, W; Alhamadsheh, M; Chan, W; Faaij, M; Fox, J; Graef, I; Haque Tuhin, MT; Jampala, R; Joo, H; Khan, J; Kumar, N; Liang, D; Liu, F; Miller, M; Pal, A; Pappas, B; Park, M; Sinha, U; Zamboni, R	1
Kashihara, M; Mizuguchi, M; Yokoyama, T	1
Kelly, JW; Nelson, LT; Paxman, RJ; Powers, ET; Webb, B; Xu, J	1
Arsequell, G; Cardoso, I; Cotrina, EY; Gales, L; Leite, JP; Llop, J; Oliveira, Â; Quintana, J	1

Reviews

2 review(s) available for diflunisal and tolcapone

Article	Year
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

8 other study(ies) available for diflunisal and tolcapone

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Enthalpy-Driven Stabilization of Transthyretin by AG10 Mimics a Naturally Occurring Genetic Variant That Protects from Transthyretin Amyloidosis. Journal of medicinal chemistry, 2018, 09-13, Volume: 61, Issue:17 Topics: Administration, Oral; Amyloid Neuropathies, Familial; Animals; Benzoates; Biomimetics; Dogs; Entropy; Female; Humans; Male; Models, Molecular; Mutation; Prealbumin; Protein Conformation; Protein Stability; Pyrazoles; Serum Albumin, Human; Thermodynamics	2018
Repositioning of the Anthelmintic Drugs Bithionol and Triclabendazole as Transthyretin Amyloidogenesis Inhibitors. Journal of medicinal chemistry, 2021, 10-14, Volume: 64, Issue:19 Topics: Amyloid Neuropathies, Familial; Anthelmintics; Bithionol; Crystallography, X-Ray; Drug Repositioning; Humans; Prealbumin; Thermodynamics; Triclabendazole	2021
Blinded potency comparison of transthyretin kinetic stabilisers by subunit exchange in human plasma. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 2021, Volume: 28, Issue:1 Topics: Amyloid; Amyloid Neuropathies, Familial; Benzoates; Benzoxazoles; Cardiomyopathies; Diflunisal; Humans; Kinetics; Prealbumin; Protein Aggregates; Protein Binding; Protein Multimerization; Protein Subunits; Pyrazoles; Tolcapone	2021
Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer Stabilizer. International journal of molecular sciences, 2020, Sep-28, Volume: 21, Issue:19 Topics: Amyloid; Benzbromarone; Benzoxazoles; Binding Sites; Binding, Competitive; Crystallography, X-Ray; Diflunisal; Drug Repositioning; Gene Expression; Humans; Hydrogen Bonding; Kinetics; Molecular Docking Simulation; Neuroprotective Agents; Prealbumin; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Stability; Recombinant Proteins; Thermodynamics; Thyroxine; Tolcapone	2020