diflunisal has been researched along with tafamidis in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (52.17) | 24.3611 |
| 2020's | 11 (47.83) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, S; Connelly, S; Johnson, SM; Kelly, JW; Mortenson, DE; Powers, ET; Wilson, IA | 1 |
| Albusairi, W; Alhamadsheh, M; Chan, W; Faaij, M; Fox, J; Graef, I; Haque Tuhin, MT; Jampala, R; Joo, H; Khan, J; Kumar, N; Liang, D; Liu, F; Miller, M; Pal, A; Pappas, B; Park, M; Sinha, U; Zamboni, R | 1 |
| Mizuguchi, M; Yokoyama, T | 2 |
| Inui, K; Kanamitsu, K; Katayama, W; Kitakami, R; Mizuguchi, M; Nakagawa, S; Nakagawa, Y; Okada, T; Sawai, Y; Toyooka, N; Yokoyama, T | 1 |
| Kashihara, M; Mizuguchi, M; Yokoyama, T | 1 |
| Adams, D; Cauquil, C; Théaudin, M | 1 |
| Sekijima, Y | 4 |
| Castaño, A; Drachman, BM; Judge, D; Maurer, MS | 1 |
| Adams, D; Algalarrondo, V; Beaudonnet, G; Cauquil, C; Labeyrie, C; Théaudin, M | 1 |
| Andersson, PL; Begum, A; Brännström, K; Iakovleva, I; Nilsson, L; Olofsson, A; Sauer-Eriksson, AE; Wijsekera, A; Zhang, J | 1 |
| Buxbaum, JN | 1 |
| Maurer, MS; Rubin, J | 1 |
| Cavallaro, T; Fabrizi, GM; Magrinelli, F; Manganelli, F; Santoro, L; Tamburin, S; Zanette, G | 1 |
| Hale, C; Lin, H; Marantz, JL; Merkel, M | 1 |
| Cristóbal Gutiérrez, H; Gómez Gómez, D; Martín Vega, MÁ; Pelayo-Negro, AL; Valero Domínguez, M | 1 |
| Kelly, JW; Nelson, LT; Paxman, RJ; Powers, ET; Webb, B; Xu, J | 1 |
| Arsequell, G; Cardoso, I; Cotrina, EY; Gales, L; Leite, JP; Llop, J; Oliveira, Â; Quintana, J | 1 |
| Benbrahim, M; Hughes, D; Norman, K; Sanchorawala, V; Siddiqi, OK | 1 |
| Katsuno, M; Koike, H | 1 |
14 review(s) available for diflunisal and tafamidis
| Article | Year |
|---|---|
Transthyretin Amyloidogenesis Inhibitors: From Discovery to Current Developments.
Topics: Amyloid; Crystallography, X-Ray; Drug Discovery; Humans; Molecular Structure; Prealbumin | 2020 |
[Familial amyloid polyneuropathies: therapeutic issues].
Topics: Amyloid Neuropathies, Familial; Antibodies, Monoclonal; Benzoxazoles; Clinical Trials as Topic; Diflunisal; Disease Progression; Doxycycline; Drug Therapy, Combination; Genetic Therapy; Heart Failure; Heart Transplantation; Humans; Kidney Failure, Chronic; Kidney Transplantation; Liver Transplantation; Myocardium; Oligonucleotides, Antisense; Renal Dialysis; RNA Interference; Serum Amyloid P-Component; Taurochenodeoxycholic Acid | 2012 |
Recent progress in the understanding and treatment of transthyretin amyloidosis.
Topics: Amyloid Neuropathies, Familial; Benzoxazoles; Diflunisal; Genetic Therapy; Humans; Liver Transplantation; Oligonucleotides, Antisense; Prealbumin; RNA, Small Interfering | 2014 |
Natural history and therapy of TTR-cardiac amyloidosis: emerging disease-modifying therapies from organ transplantation to stabilizer and silencer drugs.
Topics: Amyloid Neuropathies, Familial; Benzoxazoles; Biomarkers; Cardiomyopathies; Cyclooxygenase Inhibitors; Defibrillators, Implantable; Diflunisal; Doxycycline; Heart Failure; Humans; Oligonucleotides, Antisense; Organ Transplantation; Pacemaker, Artificial; RNA, Small Interfering | 2015 |
Transthyretin (ATTR) amyloidosis: clinical spectrum, molecular pathogenesis and disease-modifying treatments.
Topics: Amyloid Neuropathies, Familial; Benzoxazoles; Diflunisal; Humans; Mutation; Prealbumin | 2015 |
[Clinical diversity, diagnosis and treatment of hereditary amyloid neuropathy].
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Amyloid; Amyloid Neuropathies, Familial; Benzoxazoles; Diagnosis, Differential; Diflunisal; Early Diagnosis; Female; Genes, Dominant; Humans; Liver Transplantation; Male; Middle Aged; Mutation; Prealbumin | 2014 |
TTR kinetic stabilizers and TTR gene silencing: a new era in therapy for familial amyloidotic polyneuropathies.
Topics: Amyloid Neuropathies, Familial; Benzoxazoles; Clinical Trials, Phase III as Topic; Diflunisal; Disease Progression; Gene Silencing; Humans; Liver Transplantation; Prealbumin; Receptors, Albumin | 2016 |
Inhibition of the Amyloidogenesis of Transthyretin by Natural Products and Synthetic Compounds.
Topics: Amyloid; Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Benzoxazoles; Biological Products; Diflunisal; Humans; Mutation; Prealbumin | 2018 |
Treatment of hereditary and acquired forms of transthyretin amyloidosis in the era of personalized medicine: the role of randomized controlled trials.
Topics: Amyloid Neuropathies; Amyloid Neuropathies, Familial; Benzoxazoles; Diflunisal; Female; Humans; Male; Oligonucleotides; Prealbumin; Precision Medicine; Randomized Controlled Trials as Topic; RNA, Small Interfering; Treatment Outcome | 2019 |
Cardiac Amyloidosis: Overlooked, Underappreciated, and Treatable.
Topics: Amyloid Neuropathies, Familial; Amyloidosis; Arrhythmias, Cardiac; Benzoates; Benzoxazoles; Biopsy; Cardiac Pacing, Artificial; Cardiomyopathies; Diflunisal; Disease Progression; Early Diagnosis; Early Medical Intervention; Echocardiography; Electrocardiography; Heart Failure; Humans; Immunoglobulin Light-chain Amyloidosis; Immunologic Factors; Magnetic Resonance Imaging; Oligonucleotides; Prealbumin; Prognosis; Proteasome Inhibitors; Pyrazoles; Radionuclide Imaging; RNA, Small Interfering | 2020 |
Pharmacological treatment for familial amyloid polyneuropathy.
Topics: Amyloid Neuropathies, Familial; Benzoxazoles; Diflunisal; Disease Progression; Humans; Oligonucleotides; Patient Dropouts; Quality of Life; Randomized Controlled Trials as Topic; RNA, Small Interfering | 2020 |
Overview of treatments used in transthyretin-related hereditary amyloidosis: a systematic review.
Topics: Amyloid Neuropathies, Familial; Benzoxazoles; Diflunisal; Humans; Liver Transplantation; RNA, Small Interfering | 2020 |
A Review of Novel Agents and Clinical Considerations in Patients With ATTR Cardiac Amyloidosis.
Topics: Amyloid Neuropathies, Familial; Animals; Benzoxazoles; Cardiomyopathies; Cardiovascular Agents; Diflunisal; Genetic Predisposition to Disease; Humans; Mutation; Oligonucleotides; Phenotype; Prealbumin; RNA, Small Interfering; Treatment Outcome | 2021 |
The Ultrastructure of Tissue Damage by Amyloid Fibrils.
Topics: Alzheimer Disease; Amyloid; Amyloid Neuropathies, Familial; Benzoxazoles; Diflunisal; Humans; Immunoglobulin Light Chains; Immunoglobulin Light-chain Amyloidosis; Immunologic Factors; Myocardium; Neuroprotective Agents; Oligonucleotides; Peripheral Nerves; Prealbumin; Prion Diseases; RNA, Small Interfering | 2021 |
1 trial(s) available for diflunisal and tafamidis
| Article | Year |
|---|---|
Experience of patisiran with transthyretin stabilizers in patients with hereditary transthyretin-mediated amyloidosis.
Topics: Adult; Aged; Amyloid Neuropathies, Familial; Benzoxazoles; Diflunisal; Female; Humans; Male; Middle Aged; Quality of Life; RNA, Small Interfering; Surveys and Questionnaires | 2020 |
8 other study(ies) available for diflunisal and tafamidis
| Article | Year |
|---|---|
Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors.
Topics: Amyloid Neuropathies, Familial; Computer Simulation; Drug Design; Humans; Molecular Docking Simulation; Prealbumin; Protein Multimerization; Protein Stability; Small Molecule Libraries | 2017 |
Enthalpy-Driven Stabilization of Transthyretin by AG10 Mimics a Naturally Occurring Genetic Variant That Protects from Transthyretin Amyloidosis.
Topics: Administration, Oral; Amyloid Neuropathies, Familial; Animals; Benzoates; Biomimetics; Dogs; Entropy; Female; Humans; Male; Models, Molecular; Mutation; Prealbumin; Protein Conformation; Protein Stability; Pyrazoles; Serum Albumin, Human; Thermodynamics | 2018 |
Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis.
Topics: Amyloid Neuropathies, Familial; Anthraquinones; Crystallography, X-Ray; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Xanthones | 2021 |
Repositioning of the Anthelmintic Drugs Bithionol and Triclabendazole as Transthyretin Amyloidogenesis Inhibitors.
Topics: Amyloid Neuropathies, Familial; Anthelmintics; Bithionol; Crystallography, X-Ray; Drug Repositioning; Humans; Prealbumin; Thermodynamics; Triclabendazole | 2021 |
[Newly developed drug therapies for familial amyloid polyneuropathy: diflunisal and tafamidis].
Topics: Amyloid Neuropathies, Familial; Benzoxazoles; Diflunisal; Humans; Liver Transplantation; Molecular Targeted Therapy; Prealbumin; Protein Multimerization | 2014 |
Tetrabromobisphenol A Is an Efficient Stabilizer of the Transthyretin Tetramer.
Topics: Amyloid; Amyloidosis; Benzoxazoles; Binding Sites; Cell Line, Tumor; Crystallography, X-Ray; Diflunisal; Drug Design; Excipients; Half-Life; Humans; Ligands; Polybrominated Biphenyls; Prealbumin; Protein Binding; Thyroxine | 2016 |
Blinded potency comparison of transthyretin kinetic stabilisers by subunit exchange in human plasma.
Topics: Amyloid; Amyloid Neuropathies, Familial; Benzoates; Benzoxazoles; Cardiomyopathies; Diflunisal; Humans; Kinetics; Prealbumin; Protein Aggregates; Protein Binding; Protein Multimerization; Protein Subunits; Pyrazoles; Tolcapone | 2021 |
Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer Stabilizer.
Topics: Amyloid; Benzbromarone; Benzoxazoles; Binding Sites; Binding, Competitive; Crystallography, X-Ray; Diflunisal; Drug Repositioning; Gene Expression; Humans; Hydrogen Bonding; Kinetics; Molecular Docking Simulation; Neuroprotective Agents; Prealbumin; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Stability; Recombinant Proteins; Thermodynamics; Thyroxine; Tolcapone | 2020 |